Volume 7; Issue 12

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PLoS Genetics
Volume 7; Issue 12

PLoS Genetics

Volume 7; Issue 12

1

Azospirillum Genomes Reveal Transition of Bacteria from Aquatic to Terrestrial Environments

Wisniewski-Dyé, Florence, Borziak, Kirill, Khalsa-Moyers, Gurusahai, Alexandre, Gladys, Sukharnikov, Leonid O., Wuichet, Kristin, Hurst, Gregory B., McDonald, W. Hayes, Robertson, Jon S., Barbe, Valér

Journal:

Year:

2011

Language:

english

File:

PDF, 2.62 MB

english, 2011

2

Genomic Distribution and Inter-Sample Variation of Non-CpG Methylation across Human Cell Types

Ziller, Michael J., Müller, Fabian, Liao, Jing, Zhang, Yingying, Gu, Hongcang, Bock, Christoph, Boyle, Patrick, Epstein, Charles B., Bernstein, Bradley E., Lengauer, Thomas, Gnirke, Andreas, Meissner,

Journal:

Year:

2011

Language:

english

File:

PDF, 938 KB

english, 2011

3

The RNA Silencing Enzyme RNA Polymerase V Is Required for Plant Immunity

López, Ana, Ramírez, Vicente, García-Andrade, Javier, Flors, Victor, Vera, Pablo, Pikaard, Craig S.

Journal:

Year:

2011

Language:

english

File:

PDF, 750 KB

english, 2011

4

A Comprehensive Analysis of Shared Loci between Systemic Lupus Erythematosus (SLE) and Sixteen Autoimmune Diseases Reveals Limited Genetic Overlap

Ramos, Paula S., Criswell, Lindsey A., Moser, Kathy L., Comeau, Mary E., Williams, Adrienne H., Pajewski, Nicholas M., Chung, Sharon A., Graham, Robert R., Zidovetzki, Raphael, Kelly, Jennifer A., Kau

Journal:

Year:

2011

Language:

english

File:

PDF, 332 KB

english, 2011

5

Histone H3K9 Trimethylase Eggless Controls Germline Stem Cell Maintenance and Differentiation

Wang, Xiaoxi, Pan, Lei, Wang, Su, Zhou, Jian, McDowell, William, Park, Jungeun, Haug, Jeff, Staehling, Karen, Tang, Hong, Xie, Ting, Perrimon, Norbert

Journal:

Year:

2011

Language:

english

File:

PDF, 10.09 MB

english, 2011

6

DNA Methylation of the Gonadal Aromatase (cyp19a) Promoter Is Involved in Temperature-Dependent Sex Ratio Shifts in the European Sea Bass

Navarro-Martín, Laia, Viñas, Jordi, Ribas, Laia, Díaz, Noelia, Gutiérrez, Arantxa, Di Croce, Luciano, Piferrer, Francesc, Whitelaw, Emma

Journal:

Year:

2011

Language:

english

File:

PDF, 1.66 MB

english, 2011

7

Candidate Gene Screen in the Red Flour Beetle Tribolium Reveals Six3 as Ancient Regulator of Anterior Median Head and Central Complex Development

Posnien, Nico, Koniszewski, Nikolaus Dieter Bernhard, Hein, Hendrikje Jeannette, Bucher, Gregor, Desplan, Claude

Journal:

Year:

2011

Language:

english

File:

PDF, 6.92 MB

english, 2011

8

MAPK/ERK Signaling Regulates Insulin Sensitivity to Control Glucose Metabolism in Drosophila

Zhang, Wei, Thompson, Barry J., Hietakangas, Ville, Cohen, Stephen M., Rulifson, Eric

Journal:

Year:

2011

Language:

english

File:

PDF, 2.21 MB

english, 2011

9

Targeted Proteolysis of Plectin Isoform 1a Accounts for Hemidesmosome Dysfunction in Mice Mimicking the Dominant Skin Blistering Disease EBS-Ogna

Walko, Gernot, Vukasinovic, Nevena, Gross, Karin, Fischer, Irmgard, Sibitz, Sabrina, Fuchs, Peter, Reipert, Siegfried, Jungwirth, Ute, Berger, Walter, Salzer, Ulrich, Carugo, Oliviero, Castañón, Maria

Journal:

Year:

2011

Language:

english

File:

PDF, 5.69 MB

english, 2011

10

Drosophila Ribosomal Protein Mutants Control Tissue Growth Non-Autonomously via Effects on the Prothoracic Gland and Ecdysone

Lin, Jane I., Mitchell, Naomi C., Kalcina, Marina, Tchoubrieva, Elly, Stewart, Mary J., Marygold, Steven J., Walker, Cherryl D., Thomas, George, Leevers, Sally J., Pearson, Richard B., Quinn, Leonie M

Journal:

Year:

2011

Language:

english

File:

PDF, 4.91 MB

english, 2011

11

A Population Genetics-Phylogenetics Approach to Inferring Natural Selection in Coding Sequences

Wilson, Daniel J., Hernandez, Ryan D., Andolfatto, Peter, Przeworski, Molly, Nachman, Michael W.

Journal:

Year:

2011

Language:

english

File:

PDF, 602 KB

english, 2011

12

Identification of Evolutionarily Conserved Exons as Regulated Targets for the Splicing Activator Tra2β in Development

Grellscheid, Sushma, Dalgliesh, Caroline, Storbeck, Markus, Best, Andrew, Liu, Yilei, Jakubik, Miriam, Mende, Ylva, Ehrmann, Ingrid, Curk, Tomaz, Rossbach, Kristina, Bourgeois, Cyril F., Stévenin, Jam

Journal:

Year:

2011

Language:

english

File:

PDF, 5.57 MB

english, 2011

13

Mechanisms Establishing TLR4-Responsive Activation States of Inflammatory Response Genes

Escoubet-Lozach, Laure, Benner, Christopher, Kaikkonen, Minna U., Lozach, Jean, Heinz, Sven, Spann, Nathan J., Crotti, Andrea, Stender, Josh, Ghisletti, Serena, Reichart, Donna, Cheng, Christine S., L

Journal:

Year:

2011

Language:

english

File:

PDF, 2.08 MB

english, 2011

14

A Densely Interconnected Genome-Wide Network of MicroRNAs and Oncogenic Pathways Revealed Using Gene Expression Signatures

Ooi, Chia Huey, Oh, Hue Kian, Wang, Hannah Zhu'Ai, Tan, Angie Lay Keng, Wu, Jeanie, Lee, Minghui, Rha, Sun Young, Chung, Hyun Cheol, Virshup, David Marc, Tan, Patrick, Kim, Stuart K.

Journal:

Year:

2011

Language:

english

File:

PDF, 2.03 MB

english, 2011

15

Interspecific Sex in Grass Smuts and the Genetic Diversity of Their Pheromone-Receptor System

Kellner, Ronny, Vollmeister, Evelyn, Feldbrügge, Michael, Begerow, Dominik, Heitman, Joseph

Journal:

Year:

2011

Language:

english

File:

PDF, 2.88 MB

english, 2011

16

Target Site Recognition by a Diversity-Generating Retroelement

Guo, Huatao, Tse, Longping V., Nieh, Angela W., Czornyj, Elizabeth, Williams, Steven, Oukil, Sabrina, Liu, Vincent B., Miller, Jeff F., Burkholder, William F.

Journal:

Year:

2011

Language:

english

File:

PDF, 1.29 MB

english, 2011

17

Substitutions in the Amino-Terminal Tail of Neurospora Histone H3 Have Varied Effects on DNA Methylation

Adhvaryu, Keyur K., Berge, Emanuela, Tamaru, Hisashi, Freitag, Michael, Selker, Eric U., Bickmore, Wendy A.

Journal:

Year:

2011

Language:

english

File:

PDF, 918 KB

english, 2011

18

A High-Resolution Whole-Genome Map of Key Chromatin Modifications in the Adult Drosophila melanogaster

Yin, Hang, Sweeney, Sarah, Raha, Debasish, Snyder, Michael, Lin, Haifan, Reik, Wolf

Journal:

Year:

2011

Language:

english

File:

PDF, 2.96 MB

english, 2011

19

Charcot-Marie-Tooth–Linked Mutant GARS Is Toxic to Peripheral Neurons Independent of Wild-Type GARS Levels

Motley, William W., Seburn, Kevin L., Nawaz, Mir Hussain, Miers, Kathy E., Cheng, Jun, Antonellis, Anthony, Green, Eric D., Talbot, Kevin, Yang, Xiang-Lei, Fischbeck, Kenneth H., Burgess, Robert W., B

Journal:

Year:

2011

Language:

english

File:

PDF, 8.93 MB

english, 2011

20

A Complex Genomic Rearrangement Involving the Endothelin 3 Locus Causes Dermal Hyperpigmentation in the Chicken

Dorshorst, Ben, Molin, Anna-Maja, Rubin, Carl-Johan, Johansson, Anna M., Strömstedt, Lina, Pham, Manh-Hung, Chen, Chih-Feng, Hallböök, Finn, Ashwell, Chris, Andersson, Leif, Kos, Lidia

Journal:

Year:

2011

Language:

english

File:

PDF, 2.89 MB

english, 2011

21

A Novel Checkpoint and RPA Inhibitory Pathway Regulated by Rif1

Xue, Yuan, Rushton, Michael D., Maringele, Laura, Biggins, Sue

Journal:

Year:

2011

Language:

english

File:

PDF, 1.18 MB

english, 2011

22

The Major Roles of DNA Polymerases Epsilon and Delta at the Eukaryotic Replication Fork Are Evolutionarily Conserved

Miyabe, Izumi, Kunkel, Thomas A., Carr, Antony M., Copenhaver, Gregory P.

Journal:

Year:

2011

Language:

english

File:

PDF, 1.13 MB

english, 2011

23

An Anti-Checkpoint Activity for Rif1

Harari, Yaniv, Rubinstein, Linda, Kupiec, Martin, Biggins, Sue

Journal:

Year:

2011

Language:

english

File:

PDF, 132 KB

english, 2011

24

Age-Related Neuronal Degeneration: Complementary Roles of Nucleotide Excision Repair and Transcription-Coupled Repair in Preventing Neuropathology

Jaarsma, Dick, van der Pluijm, Ingrid, de Waard, Monique C., Haasdijk, Elize D., Brandt, Renata, Vermeij, Marcel, Rijksen, Yvonne, Maas, Alex, van Steeg, Harry, Hoeijmakers, Jan H. J., van der Horst,

Journal:

Year:

2011

Language:

english

File:

PDF, 1.30 MB

english, 2011

25

HIF-1 Regulates Iron Homeostasis in Caenorhabditis elegans by Activation and Inhibition of Genes Involved in Iron Uptake and Storage

Romney, Steven Joshua, Newman, Ben S., Thacker, Colin, Leibold, Elizabeth A., Johnson, Randall S.

Journal:

Year:

2011

Language:

english

File:

PDF, 867 KB

english, 2011

26

A Genetic Screening Strategy Identifies Novel Regulators of the Proteostasis Network

Silva, M. Catarina, Fox, Susan, Beam, Monica, Thakkar, Happy, Amaral, Margarida D., Morimoto, Richard I., Serio, Tricia R.

Journal:

Year:

2011

Language:

english

File:

PDF, 1.89 MB

english, 2011

27

Genome Instability and Transcription Elongation Impairment in Human Cells Depleted of THO/TREX

Domínguez-Sánchez, María S., Barroso, Sonia, Gómez-González, Belén, Luna, Rosa, Aguilera, Andrés, Pearson, Christopher E.

Journal:

Year:

2011

Language:

english

File:

PDF, 4.40 MB

english, 2011

28

Integrating Genome-Wide Genetic Variations and Monocyte Expression Data Reveals Trans-Regulated Gene Modules in Humans

Rotival, Maxime, Zeller, Tanja, Wild, Philipp S., Maouche, Seraya, Szymczak, Silke, Schillert, Arne, Castagné, Raphaele, Deiseroth, Arne, Proust, Carole, Brocheton, Jessy, Godefroy, Tiphaine, Perret,

Journal:

Year:

2011

Language:

english

File:

PDF, 1.19 MB

english, 2011

29

SREBP Coordinates Iron and Ergosterol Homeostasis to Mediate Triazole Drug and Hypoxia Responses in the Human Fungal Pathogen Aspergillus fumigatus

Blatzer, Michael, Barker, Bridget M., Willger, Sven D., Beckmann, Nicola, Blosser, Sara J., Cornish, Elizabeth J., Mazurie, Aurelien, Grahl, Nora, Haas, Hubertus, Cramer, Robert A., Madhani, Hiten D.

Journal:

Year:

2011

Language:

english

File:

PDF, 7.01 MB

english, 2011

30

Hierarchical Generalized Linear Models for Multiple Groups of Rare and Common Variants: Jointly Estimating Group and Individual-Variant Effects

Yi, Nengjun, Liu, Nianjun, Zhi, Degui, Li, Jun, Schork, Nicholas J.

Journal:

Year:

2011

Language:

english

File:

PDF, 983 KB

english, 2011

31

Mining the LIPG Allelic Spectrum Reveals the Contribution of Rare and Common Regulatory Variants to HDL Cholesterol

Khetarpal, Sumeet A., Edmondson, Andrew C., Raghavan, Avanthi, Neeli, Hemanth, Jin, Weijun, Badellino, Karen O., Demissie, Serkalem, Manning, Alisa K., DerOhannessian, Stephanie L., Wolfe, Megan L., C

Journal:

Year:

2011

Language:

english

File:

PDF, 574 KB

english, 2011

32

Widespread Cotranslational Formation of Protein Complexes

Duncan, Caia D. S., Mata, Juan, Wolf, Dieter A.

Journal:

Year:

2011

Language:

english

File:

PDF, 364 KB

english, 2011

33

The FGFR4-G388R Polymorphism Promotes Mitochondrial STAT3 Serine Phosphorylation to Facilitate Pituitary Growth Hormone Cell Tumorigenesis

Tateno, Toru, Asa, Sylvia L., Zheng, Lei, Mayr, Thomas, Ullrich, Axel, Ezzat, Shereen, Low, Malcolm J.

Journal:

Year:

2011

Language:

english

File:

PDF, 8.79 MB

english, 2011

34

Acute Multiple Organ Failure in Adult Mice Deleted for the Developmental Regulator Wt1

Chau, You-Ying, Brownstein, David, Mjoseng, Heidi, Lee, Wen-Chin, Buza-Vidas, Natalija, Nerlov, Claus, Jacobsen, Sten Eirik, Perry, Paul, Berry, Rachel, Thornburn, Anna, Sexton, David, Morton, Nik, Ho

Journal:

Year:

2011

Language:

english

File:

PDF, 7.35 MB

english, 2011

35

Ancestral Components of Admixed Genomes in a Mexican Cohort

Johnson, Nicholas A., Coram, Marc A., Shriver, Mark D., Romieu, Isabelle, Barsh, Gregory S., London, Stephanie J., Tang, Hua, Copenhaver, Gregory P.

Journal:

Year:

2011

Language:

english

File:

PDF, 552 KB

english, 2011

36

An Assessment of the Individual and Collective Effects of Variants on Height Using Twins and a Developmentally Informative Study Design

Vrieze, Scott I., McGue, Matt, Miller, Michael B., Legrand, Lisa N., Schork, Nicholas J., Iacono, William G., Gibson, Greg

Journal:

Year:

2011

Language:

english

File:

PDF, 561 KB

english, 2011

37

Duox, Flotillin-2, and Src42A Are Required to Activate or Delimit the Spread of the Transcriptional Response to Epidermal Wounds in Drosophila

Juarez, Michelle T., Patterson, Rachel A., Sandoval-Guillen, Efren, McGinnis, William, Krasnow, Mark

Journal:

Year:

2011

Language:

english

File:

PDF, 3.31 MB

english, 2011

38

Repetitive Elements May Comprise Over Two-Thirds of the Human Genome

de Koning, A. P. Jason, Gu, Wanjun, Castoe, Todd A., Batzer, Mark A., Pollock, David D., Copenhaver, Gregory P.

Journal:

Year:

2011

Language:

english

File:

PDF, 1.32 MB

english, 2011

39

The Caenorhabditis elegans Synthetic Multivulva Genes Prevent Ras Pathway Activation by Tightly Repressing Global Ectopic Expression of lin-3 EGF

Saffer, Adam M., Kim, Dong Hyun, van Oudenaarden, Alexander, Horvitz, H. Robert, Chisholm, Andrew D.

Journal:

Year:

2011

Language:

english

File:

PDF, 3.17 MB

english, 2011

40

The Fission Yeast Stress-Responsive MAPK Pathway Promotes Meiosis via the Phosphorylation of Pol II CTD in Response to Environmental and Feedback Cues

Sukegawa, Yuko, Yamashita, Akira, Yamamoto, Masayuki, Lichten, Michael

Journal:

Year:

2011

Language:

english

File:

PDF, 4.15 MB

english, 2011

41

Genome-Wide Meta-Analysis of Five Asian Cohorts Identifies PDGFRA as a Susceptibility Locus for Corneal Astigmatism

Fan, Qiao, Zhou, Xin, Khor, Chiea-Chuen, Cheng, Ching-Yu, Goh, Liang-Kee, Sim, Xueling, Tay, Wan-Ting, Li, Yi-Ju, Ong, Rick Twee-Hee, Suo, Chen, Cornes, Belinda, Ikram, Mohammad Kamran, Chia, Kee-Seng

Journal:

Year:

2011

Language:

english

File:

PDF, 302 KB

english, 2011

42

The RNA–Methyltransferase Misu (NSun2) Poises Epidermal Stem Cells to Differentiate

Blanco, Sandra, Kurowski, Agata, Nichols, Jennifer, Watt, Fiona M., Benitah, Salvador Aznar, Frye, Michaela, Oro, Tony

Journal:

Year:

2011

Language:

english

File:

PDF, 3.36 MB

english, 2011

43

Plasticity of BRCA2 Function in Homologous Recombination: Genetic Interactions of the PALB2 and DNA Binding Domains

Siaud, Nicolas, Barbera, Maria A., Egashira, Akinori, Lam, Isabel, Christ, Nicole, Schlacher, Katharina, Xia, Bing, Jasin, Maria, Maizels, Nancy

Journal:

Year:

2011

Language:

english

File:

PDF, 2.12 MB

english, 2011

44

Transcription Is Required to Establish Maternal Imprinting at the Prader-Willi Syndrome and Angelman Syndrome Locus

Smith, Emily Y., Futtner, Christopher R., Chamberlain, Stormy J., Johnstone, Karen A., Resnick, James L., Ferguson-Smith, Anne C.

Journal:

Year:

2011

Language:

english

File:

PDF, 717 KB

english, 2011

45

Common Variants Show Predicted Polygenic Effects on Height in the Tails of the Distribution, Except in Extremely Short Individuals

Chan, Yingleong, Holmen, Oddgeir L., Dauber, Andrew, Vatten, Lars, Havulinna, Aki S., Skorpen, Frank, Kvaløy, Kirsti, Silander, Kaisa, Nguyen, Thutrang T., Willer, Cristen, Boehnke, Michael, Perola, M

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Year:

2011

Language:

english

File:

PDF, 576 KB

english, 2011

46

The Connection between Space and Thinking: An Interview with Rafael Viñoly

Gitschier, Jane

Journal:

Year:

2011

Language:

english

File:

PDF, 258 KB

english, 2011

47

A Functional Phylogenomic View of the Seed Plants

Lee, Ernest K., Cibrian-Jaramillo, Angelica, Kolokotronis, Sergios-Orestis, Katari, Manpreet S., Stamatakis, Alexandros, Ott, Michael, Chiu, Joanna C., Little, Damon P., Stevenson, Dennis Wm., McCombi

Journal:

Year:

2011

Language:

english

File:

PDF, 772 KB

english, 2011

48

Autosomal Recessive Dilated Cardiomyopathy due to DOLK Mutations Results from Abnormal Dystroglycan O-Mannosylation

Lefeber, Dirk J., de Brouwer, Arjan P. M., Morava, Eva, Riemersma, Moniek, Schuurs-Hoeijmakers, Janneke H. M., Absmanner, Birgit, Verrijp, Kiek, van den Akker, Willem M. R., Huijben, Karin, Steenberge

Journal:

Year:

2011

Language:

english

File:

PDF, 2.55 MB

english, 2011

49

Ror2 Enhances Polarity and Directional Migration of Primordial Germ Cells

Laird, Diana J., Altshuler-Keylin, Svetlana, Kissner, Michael D., Zhou, Xin, Anderson, Kathryn V., Tam, Patrick P. L.

Journal:

Year:

2011

Language:

english

File:

PDF, 6.37 MB

english, 2011

50

Identification of a Genomic Reservoir for New TRIM Genes in Primate Genomes

Han, Kyudong, Lou, Dianne I., Sawyer, Sara L., Worobey, Michael

Journal:

Year:

2011

Language:

english

File:

PDF, 2.01 MB

english, 2011

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