Volume 7; Issue 4

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PLoS Genetics
Volume 7; Issue 4

PLoS Genetics

Volume 7; Issue 4

1

Does Positive Selection Drive Transcription Factor Binding Site Turnover? A Test with Drosophila Cis-Regulatory Modules

He, Bin Z., Holloway, Alisha K., Maerkl, Sebastian J., Kreitman, Martin, Petrov, Dmitri A.

Journal:

Year:

2011

Language:

english

File:

PDF, 382 KB

english, 2011

2

Reciprocal Sign Epistasis between Frequently Experimentally Evolved Adaptive Mutations Causes a Rugged Fitness Landscape

Kvitek, Daniel J., Sherlock, Gavin, Zhang, Jianzhi

Journal:

Year:

2011

Language:

english

File:

PDF, 4.31 MB

english, 2011

3

GWAS of Follicular Lymphoma Reveals Allelic Heterogeneity at 6p21.32 and Suggests Shared Genetic Susceptibility with Diffuse Large B-cell Lymphoma

Smedby, Karin E., Foo, Jia Nee, Skibola, Christine F., Darabi, Hatef, Conde, Lucia, Hjalgrim, Henrik, Kumar, Vikrant, Chang, Ellen T., Rothman, Nathaniel, Cerhan, James R., Brooks-Wilson, Angela R., R

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Year:

2011

Language:

english

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PDF, 651 KB

english, 2011

4

Quantitative Fitness Analysis Shows That NMD Proteins and Many Other Protein Complexes Suppress or Enhance Distinct Telomere Cap Defects

Addinall, Stephen Gregory, Holstein, Eva-Maria, Lawless, Conor, Yu, Min, Chapman, Kaye, Banks, A. Peter, Ngo, Hien-Ping, Maringele, Laura, Taschuk, Morgan, Young, Alexander, Ciesiolka, Adam, Lister, A

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Year:

2011

Language:

english

File:

PDF, 4.10 MB

english, 2011

5

Evolution Meets Disease: Penetrance and Functional Epistasis of Mitochondrial tRNA Mutations

Moreno-Loshuertos, Raquel, Ferrín, Gustavo, Acín-Pérez, Rebeca, Gallardo, M. Esther, Viscomi, Carlo, Pérez-Martos, Acisclo, Zeviani, Massimo, Fernández-Silva, Patricio, Enríquez, José Antonio, Larsson

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Year:

2011

Language:

english

File:

PDF, 2.63 MB

english, 2011

6

Genome-Wide Association Study Using Extreme Truncate Selection Identifies Novel Genes Affecting Bone Mineral Density and Fracture Risk

Duncan, Emma L., Danoy, Patrick, Kemp, John P., Leo, Paul J., McCloskey, Eugene, Nicholson, Geoffrey C., Eastell, Richard, Prince, Richard L., Eisman, John A., Jones, Graeme, Sambrook, Philip N., Reid

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Year:

2011

Language:

english

File:

PDF, 322 KB

english, 2011

7

Dynamic Regulation of H3K27 Trimethylation during Arabidopsis Differentiation

Lafos, Marcel, Kroll, Phillip, Hohenstatt, Mareike L., Thorpe, Frazer L., Clarenz, Oliver, Schubert, Daniel, Kakutani, Tetsuji

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Year:

2011

Language:

english

File:

PDF, 1.59 MB

english, 2011

8

Identification and Functional Validation of the Novel Antimalarial Resistance Locus PF10_0355 in Plasmodium falciparum

Van Tyne, Daria, Park, Daniel J., Schaffner, Stephen F., Neafsey, Daniel E., Angelino, Elaine, Cortese, Joseph F., Barnes, Kayla G., Rosen, David M., Lukens, Amanda K., Daniels, Rachel F., Milner, Dan

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Year:

2011

Language:

english

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PDF, 1.12 MB

english, 2011

9

The Phylogenetic Origin of oskar Coincided with the Origin of Maternally Provisioned Germ Plasm and Pole Cells at the Base of the Holometabola

Lynch, Jeremy A., Özüak, Orhan, Khila, Abderrahman, Abouheif, Ehab, Desplan, Claude, Roth, Siegfried, Kopp, Artyom

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Year:

2011

Language:

english

File:

PDF, 394 KB

english, 2011

10

Eight Common Genetic Variants Associated with Serum DHEAS Levels Suggest a Key Role in Ageing Mechanisms

Zhai, Guangju, Teumer, Alexander, Stolk, Lisette, Perry, John R. B., Vandenput, Liesbeth, Coviello, Andrea D., Koster, Annemarie, Bell, Jordana T., Bhasin, Shalender, Eriksson, Joel, Eriksson, Anna, E

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Year:

2011

Language:

english

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PDF, 833 KB

english, 2011

11

Chromatin Organization in Sperm May Be the Major Functional Consequence of Base Composition Variation in the Human Genome

Vavouri, Tanya, Lehner, Ben, Lieb, Jason D.

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Year:

2011

Language:

english

File:

PDF, 1.48 MB

english, 2011

12

Fluctuations in spo0A Transcription Control Rare Developmental Transitions in Bacillus subtilis

Mirouze, Nicolas, Prepiak, Peter, Dubnau, David, Burkholder, William F.

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Year:

2011

Language:

english

File:

PDF, 416 KB

english, 2011

13

Alkylation Base Damage Is Converted into Repairable Double-Strand Breaks and Complex Intermediates in G2 Cells Lacking AP Endonuclease

Ma, Wenjian, Westmoreland, Jim W., Gordenin, Dmitry A., Resnick, Mike A., Maizels, Nancy

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Year:

2011

Language:

english

File:

PDF, 429 KB

english, 2011

14

An Evolutionary Genomic Approach to Identify Genes Involved in Human Birth Timing

Plunkett, Jevon, Doniger, Scott, Orabona, Guilherme, Morgan, Thomas, Haataja, Ritva, Hallman, Mikko, Puttonen, Hilkka, Menon, Ramkumar, Kuczynski, Edward, Norwitz, Errol, Snegovskikh, Victoria, Paloti

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Year:

2011

Language:

english

File:

PDF, 675 KB

english, 2011

15

Genome Analysis Reveals Interplay between 5′UTR Introns and Nuclear mRNA Export for Secretory and Mitochondrial Genes

Cenik, Can, Chua, Hon Nian, Zhang, Hui, Tarnawsky, Stefan P., Akef, Abdalla, Derti, Adnan, Tasan, Murat, Moore, Melissa J., Palazzo, Alexander F., Roth, Frederick P., Snyder, Michael

Journal:

Year:

2011

Language:

english

File:

PDF, 1.36 MB

english, 2011

16

14-3-3 Proteins Regulate Exonuclease 1–Dependent Processing of Stalled Replication Forks

Engels, Kim, Giannattasio, Michele, Muzi-Falconi, Marco, Lopes, Massimo, Ferrari, Stefano, Pearson, Christopher E.

Journal:

Year:

2011

Language:

english

File:

PDF, 1.59 MB

english, 2011

17

Adaptations to Climate-Mediated Selective Pressures in Humans

Hancock, Angela M., Witonsky, David B., Alkorta-Aranburu, Gorka, Beall, Cynthia M., Gebremedhin, Amha, Sukernik, Rem, Utermann, Gerd, Pritchard, Jonathan K., Coop, Graham, Di Rienzo, Anna, Nachman, Mi

Journal:

Year:

2011

Language:

english

File:

PDF, 2.23 MB

english, 2011

18

The Complete Spectrum of Yeast Chromosome Instability Genes Identifies Candidate CIN Cancer Genes and Functional Roles for ASTRA Complex Components

Stirling, Peter C., Bloom, Michelle S., Solanki-Patil, Tejomayee, Smith, Stephanie, Sipahimalani, Payal, Li, Zhijian, Kofoed, Megan, Ben-Aroya, Shay, Myung, Kyungjae, Hieter, Philip, Snyder, Michael

Journal:

Year:

2011

Language:

english

File:

PDF, 283 KB

english, 2011

19

Transferability of Type 2 Diabetes Implicated Loci in Multi-Ethnic Cohorts from Southeast Asia

Sim, Xueling, Ong, Rick Twee-Hee, Suo, Chen, Tay, Wan-Ting, Liu, Jianjun, Ng, Daniel Peng-Keat, Boehnke, Michael, Chia, Kee-Seng, Wong, Tien-Yin, Seielstad, Mark, Teo, Yik-Ying, Tai, E-Shyong, Gibson,

Journal:

Year:

2011

Language:

english

File:

PDF, 1.05 MB

english, 2011

20

Tissue-Autonomous Function of Drosophila Seipin in Preventing Ectopic Lipid Droplet Formation

Tian, Yuan, Bi, Junfeng, Shui, Guanghou, Liu, Zhonghua, Xiang, Yanhui, Liu, Yuan, Wenk, Markus R., Yang, Hongyuan, Huang, Xun, Ashrafi, Kaveh

Journal:

Year:

2011

Language:

english

File:

PDF, 5.71 MB

english, 2011

21

Survival Motor Neuron Protein Regulates Stem Cell Division, Proliferation, and Differentiation in Drosophila

Grice, Stuart J., Liu, Ji-Long, Rulifson, Eric

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Year:

2011

Language:

english

File:

PDF, 13.84 MB

english, 2011

22

Evolution of Vertebrate Transient Receptor Potential Vanilloid 3 Channels: Opposite Temperature Sensitivity between Mammals and Western Clawed Frogs

Saito, Shigeru, Fukuta, Naomi, Shingai, Ryuzo, Tominaga, Makoto, Zhang, Jianzhi

Journal:

Year:

2011

Language:

english

File:

PDF, 1.28 MB

english, 2011

23

Genomic Instability, Defective Spermatogenesis, Immunodeficiency, and Cancer in a Mouse Model of the RIDDLE Syndrome

Bohgaki, Toshiyuki, Bohgaki, Miyuki, Cardoso, Renato, Panier, Stephanie, Zeegers, Dimphy, Li, Li, Stewart, Grant S., Sanchez, Otto, Hande, M. Prakash, Durocher, Daniel, Hakem, Anne, Hakem, Razqallah,

Journal:

Year:

2011

Language:

english

File:

PDF, 534 KB

english, 2011

24

Loss-of-Function Mutations in PTPN11 Cause Metachondromatosis, but Not Ollier Disease or Maffucci Syndrome

Bowen, Margot E., Boyden, Eric D., Holm, Ingrid A., Campos-Xavier, Belinda, Bonafé, Luisa, Superti-Furga, Andrea, Ikegawa, Shiro, Cormier-Daire, Valerie, Bovée, Judith V., Pansuriya, Twinkal C., de So

Journal:

Year:

2011

Language:

english

File:

PDF, 1.05 MB

english, 2011

25

Epigenetic Regulation of Cell Type–Specific Expression Patterns in the Human Mammary Epithelium

Maruyama, Reo, Choudhury, Sibgat, Kowalczyk, Adam, Bessarabova, Marina, Beresford-Smith, Bryan, Conway, Thomas, Kaspi, Antony, Wu, Zhenhua, Nikolskaya, Tatiana, Merino, Vanessa F., Lo, Pang-Kuo, Liu,

Journal:

Year:

2011

Language:

english

File:

PDF, 339 KB

english, 2011

26

Variable Pathogenicity Determines Individual Lifespan in Caenorhabditis elegans

Sánchez-Blanco, Adolfo, Kim, Stuart K., Copenhaver, Gregory P.

Journal:

Year:

2011

Language:

english

File:

PDF, 2.51 MB

english, 2011

27

Incorporating Biological Pathways via a Markov Random Field Model in Genome-Wide Association Studies

Chen, Min, Cho, Judy, Zhao, Hongyu, Allison, David B.

Journal:

Year:

2011

Language:

english

File:

PDF, 659 KB

english, 2011

28

Protein Phosphatase 2A Controls Ethylene Biosynthesis by Differentially Regulating the Turnover of ACC Synthase Isoforms

Skottke, Kyle R., Yoon, Gyeong Mee, Kieber, Joseph J., DeLong, Alison, Ecker, Joseph R.

Journal:

Year:

2011

Language:

english

File:

PDF, 345 KB

english, 2011

29

Enhanced Statistical Tests for GWAS in Admixed Populations: Assessment using African Americans from CARe and a Breast Cancer Consortium

Pasaniuc, Bogdan, Zaitlen, Noah, Lettre, Guillaume, Chen, Gary K., Tandon, Arti, Kao, W. H. Linda, Ruczinski, Ingo, Fornage, Myriam, Siscovick, David S., Zhu, Xiaofeng, Larkin, Emma, Lange, Leslie A.,

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Year:

2011

Language:

english

File:

PDF, 652 KB

english, 2011

30

Genome-Wide Association Analysis of Soluble ICAM-1 Concentration Reveals Novel Associations at the NFKBIK, PNPLA3, RELA, and SH2B3 Loci

Paré, Guillaume, Ridker, Paul M., Rose, Lynda, Barbalic, Maja, Dupuis, Josée, Dehghan, Abbas, Bis, Joshua C., Benjamin, Emelia J., Shiffman, Dov, Parker, Alexander N., Chasman, Daniel I., Georges, Mic

Journal:

Year:

2011

Language:

english

File:

PDF, 310 KB

english, 2011

31

Ribosomal DNA Deletions Modulate Genome-Wide Gene Expression: “rDNA–Sensitive” Genes and Natural Variation

Paredes, Silvana, Branco, Alan T., Hartl, Daniel L., Maggert, Keith A., Lemos, Bernardo, Clark, Andrew G.

Journal:

Year:

2011

Language:

english

File:

PDF, 517 KB

english, 2011

32

A Sustained Dietary Change Increases Epigenetic Variation in Isogenic Mice

Li, Cheryl C. Y., Cropley, Jennifer E., Cowley, Mark J., Preiss, Thomas, Martin, David I. K., Suter, Catherine M., Copenhaver, Gregory P.

Journal:

Year:

2011

Language:

english

File:

PDF, 1.21 MB

english, 2011

33

The Liberation of Embryonic Stem Cells

Blair, Kathryn, Wray, Jason, Smith, Austin, Beier, David R.

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Year:

2011

Language:

english

File:

PDF, 184 KB

english, 2011

34

PTG Depletion Removes Lafora Bodies and Rescues the Fatal Epilepsy of Lafora Disease

Turnbull, Julie, DePaoli-Roach, Anna A., Zhao, Xiaochu, Cortez, Miguel A., Pencea, Nela, Tiberia, Erica, Piliguian, Mark, Roach, Peter J., Wang, Peixiang, Ackerley, Cameron A., Minassian, Berge A., Fr

Journal:

Year:

2011

Language:

english

File:

PDF, 231 KB

english, 2011

35

Mouse Genome-Wide Association and Systems Genetics Identify Asxl2 As a Regulator of Bone Mineral Density and Osteoclastogenesis

Farber, Charles R., Bennett, Brian J., Orozco, Luz, Zou, Wei, Lira, Ana, Kostem, Emrah, Kang, Hyun Min, Furlotte, Nicholas, Berberyan, Ani, Ghazalpour, Anatole, Suwanwela, Jaijam, Drake, Thomas A., Es

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Year:

2011

Language:

english

File:

PDF, 3.62 MB

english, 2011

36

DNA Damage, Somatic Aneuploidy, and Malignant Sarcoma Susceptibility in Muscular Dystrophies

Schmidt, Wolfgang M., Uddin, Mohammed H., Dysek, Sandra, Moser-Thier, Karin, Pirker, Christine, Höger, Harald, Ambros, Inge M., Ambros, Peter F., Berger, Walter, Bittner, Reginald E., Orr, Harry T.

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Year:

2011

Language:

english

File:

PDF, 5.67 MB

english, 2011

37

Deficiency of Huntingtin Has Pleiotropic Effects in the Social Amoeba Dictyostelium discoideum

Myre, Michael A., Lumsden, Amanda L., Thompson, Morgan N., Wasco, Wilma, MacDonald, Marcy E., Gusella, James F., Barsh, Gregory S.

Journal:

Year:

2011

Language:

english

File:

PDF, 545 KB

english, 2011

38

A Large-Scale Complex Haploinsufficiency-Based Genetic Interaction Screen in Candida albicans: Analysis of the RAM Network during Morphogenesis

Bharucha, Nike, Chabrier-Roselló, Yeissa, Xu, Tao, Johnson, Cole, Sobczynski, Sarah, Song, Qingxuan, Dobry, Craig J., Eckwahl, Matthew J., Anderson, Christopher P., Benjamin, Andrew J., Kumar, Anuj, K

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Year:

2011

Language:

english

File:

PDF, 457 KB

english, 2011

39

The Exocyst Protein Sec10 Interacts with Polycystin-2 and Knockdown Causes PKD-Phenotypes

Fogelgren, Ben, Lin, Shin-Yi, Zuo, Xiaofeng, Jaffe, Kimberly M., Park, Kwon Moo, Reichert, Ryan J., Bell, P. Darwin, Burdine, Rebecca D., Lipschutz, Joshua H., Dutcher, Susan K.

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Year:

2011

Language:

english

File:

PDF, 5.61 MB

english, 2011

40

The History of African Gene Flow into Southern Europeans, Levantines, and Jews

Moorjani, Priya, Patterson, Nick, Hirschhorn, Joel N., Keinan, Alon, Hao, Li, Atzmon, Gil, Burns, Edward, Ostrer, Harry, Price, Alkes L., Reich, David, McVean, Gil

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Year:

2011

Language:

english

File:

PDF, 525 KB

english, 2011

41

ESR1 Is Co-Expressed with Closely Adjacent Uncharacterised Genes Spanning a Breast Cancer Susceptibility Locus at 6q25.1

Dunbier, Anita K., Anderson, Helen, Ghazoui, Zara, Lopez-Knowles, Elena, Pancholi, Sunil, Ribas, Ricardo, Drury, Suzanne, Sidhu, Kally, Leary, Alexandra, Martin, Lesley-Ann, Dowsett, Mitch, Horwitz, M

Journal:

Year:

2011

Language:

english

File:

PDF, 317 KB

english, 2011

42

Towards Establishment of a Rice Stress Response Interactome

Seo, Young-Su, Chern, Mawsheng, Bartley, Laura E., Han, Muho, Jung, Ki-Hong, Lee, Insuk, Walia, Harkamal, Richter, Todd, Xu, Xia, Cao, Peijian, Bai, Wei, Ramanan, Rajeshwari, Amonpant, Fawn, Arul, Log

Journal:

Year:

2011

Language:

english

File:

PDF, 1.17 MB

english, 2011

43

NK Cell Receptor/H2-Dk–Dependent Host Resistance to Viral Infection Is Quantitatively Modulated by H2q Inhibitory Signals

Fodil-Cornu, Nassima, Loredo-Osti, J. Concepción, Vidal, Silvia M., Roopenian, Derry C.

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Year:

2011

Language:

english

File:

PDF, 417 KB

english, 2011

44

PDP-1 Links the TGF-β and IIS Pathways to Regulate Longevity, Development, and Metabolism

Narasimhan, Sri Devi, Yen, Kelvin, Bansal, Ankita, Kwon, Eun-Soo, Padmanabhan, Srivatsan, Tissenbaum, Heidi A., Kim, Stuart K.

Journal:

Year:

2011

Language:

english

File:

PDF, 2.18 MB

english, 2011

45

Long-Lost Relative Claims Orphan Gene: oskar in a Wasp

Extavour, Cassandra G., Kopp, Artyom

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Year:

2011

Language:

english

File:

PDF, 86 KB

english, 2011

46

Phosphorylation-Dependent Differential Regulation of Plant Growth, Cell Death, and Innate Immunity by the Regulatory Receptor-Like Kinase BAK1

Schwessinger, Benjamin, Roux, Milena, Kadota, Yasuhiro, Ntoukakis, Vardis, Sklenar, Jan, Jones, Alexandra, Zipfel, Cyril, Guttman, David S.

Journal:

Year:

2011

Language:

english

File:

PDF, 515 KB

english, 2011

47

Arabidopsis HDA6 Regulates Locus-Directed Heterochromatin Silencing in Cooperation with MET1

To, Taiko Kim, Kim, Jong-Myong, Matsui, Akihiro, Kurihara, Yukio, Morosawa, Taeko, Ishida, Junko, Tanaka, Maho, Endo, Takaho, Kakutani, Tetsuji, Toyoda, Tetsuro, Kimura, Hiroshi, Yokoyama, Shigeyuki,

Journal:

Year:

2011

Language:

english

File:

PDF, 379 KB

english, 2011

48

Beyond Missing Heritability: Prediction of Complex Traits

Makowsky, Robert, Pajewski, Nicholas M., Klimentidis, Yann C., Vazquez, Ana I., Duarte, Christine W., Allison, David B., de los Campos, Gustavo, Gibson, Greg

Journal:

Year:

2011

Language:

english

File:

PDF, 366 KB

english, 2011

49

Genome-Wide Meta-Analysis Identifies Regions on 7p21 (AHR) and 15q24 (CYP1A2) As Determinants of Habitual Caffeine Consumption

Cornelis, Marilyn C., Monda, Keri L., Yu, Kai, Paynter, Nina, Azzato, Elizabeth M., Bennett, Siiri N., Berndt, Sonja I., Boerwinkle, Eric, Chanock, Stephen, Chatterjee, Nilanjan, Couper, David, Curhan

Journal:

Year:

2011

Language:

english

File:

PDF, 281 KB

english, 2011

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