Volume 8; Issue 6

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PLoS Genetics
Volume 8; Issue 6

PLoS Genetics

Volume 8; Issue 6

1

Adaptive Introgression across Species Boundaries in Heliconius Butterflies

Pardo-Diaz, Carolina, Salazar, Camilo, Baxter, Simon W., Merot, Claire, Figueiredo-Ready, Wilsea, Joron, Mathieu, McMillan, W. Owen, Jiggins, Chris D., R. Kronforst, Marcus

Journal:

Year:

2012

Language:

english

File:

PDF, 628 KB

english, 2012

2

The Histone Demethylase Jhdm1a Regulates Hepatic Gluconeogenesis

Pan, Dongning, Mao, Chunxiao, Zou, Tie, Yao, Annie Y., Cooper, Marcus P., Boyartchuk, Victor, Wang, Yong-Xu, Zierath, Juleen R.

Journal:

Year:

2012

Language:

english

File:

PDF, 835 KB

english, 2012

3

The Mechanism for RNA Recognition by ANTAR Regulators of Gene Expression

Ramesh, Arati, DebRoy, Sruti, Goodson, Jonathan R., Fox, Kristina A., Faz, Herbey, Garsin, Danielle A., Winkler, Wade C., Burkholder, William F.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.23 MB

english, 2012

4

Extensive Evolutionary Changes in Regulatory Element Activity during Human Origins Are Associated with Altered Gene Expression and Positive Selection

Shibata, Yoichiro, Sheffield, Nathan C., Fedrigo, Olivier, Babbitt, Courtney C., Wortham, Matthew, Tewari, Alok K., London, Darin, Song, Lingyun, Lee, Bum-Kyu, Iyer, Vishwanath R., Parker, Stephen C.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.56 MB

english, 2012

5

Selection-Driven Gene Loss in Bacteria

Koskiniemi, Sanna, Sun, Song, Berg, Otto G., Andersson, Dan I., Casadesús, Josep

Journal:

Year:

2012

Language:

english

File:

PDF, 391 KB

english, 2012

6

Phylogenomic Analysis Reveals Dynamic Evolutionary History of the Drosophila Heterochromatin Protein 1 (HP1) Gene Family

Levine, Mia T., McCoy, Connor, Vermaak, Danielle, Lee, Yuh Chwen G., Hiatt, Mary Alice, Matsen, Frederick A., Malik, Harmit S., Jones, Corbin D.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.07 MB

english, 2012

7

The CCR4-NOT Complex Is Implicated in the Viability of Aneuploid Yeasts

Tange, Yoshie, Kurabayashi, Atsushi, Goto, Bunshiro, Hoe, Kwang-Lae, Kim, Dong-Uk, Park, Han-Oh, Hayles, Jacqueline, Chikashige, Yuji, Tsutumi, Chihiro, Hiraoka, Yasushi, Yamao, Fumiaki, Nurse, Paul,

Journal:

Year:

2012

Language:

english

File:

PDF, 7.82 MB

english, 2012

8

Stimulation of Host Immune Defenses by a Small Molecule Protects C. elegans from Bacterial Infection

Pukkila-Worley, Read, Feinbaum, Rhonda, Kirienko, Natalia V., Larkins-Ford, Jonah, Conery, Annie L., Ausubel, Frederick M., Ashrafi, Kaveh

Journal:

Year:

2012

Language:

english

File:

PDF, 1.13 MB

english, 2012

9

Rare Copy Number Variants Observed in Hereditary Breast Cancer Cases Disrupt Genes in Estrogen Signaling and TP53 Tumor Suppression Network

Pylkäs, Katri, Vuorela, Mikko, Otsukka, Meeri, Kallioniemi, Anne, Jukkola-Vuorinen, Arja, Winqvist, Robert, Horwitz, Marshall S.

Journal:

Year:

2012

Language:

english

File:

PDF, 290 KB

english, 2012

10

The Regulatory Network of Natural Competence and Transformation of Vibrio cholerae

Lo Scrudato, Mirella, Blokesch, Melanie, Casadesús, Josep

Journal:

Year:

2012

Language:

english

File:

PDF, 2.45 MB

english, 2012

11

Synaptonemal Complex Components Persist at Centromeres and Are Required for Homologous Centromere Pairing in Mouse Spermatocytes

Bisig, C. Gaston, Guiraldelli, Michel F., Kouznetsova, Anna, Scherthan, Harry, Höög, Christer, Dawson, Dean S., Pezza, Roberto J., Hawley, R. Scott

Journal:

Year:

2012

Language:

english

File:

PDF, 4.34 MB

english, 2012

12

In Vivo Effects of Histone H3 Depletion on Nucleosome Occupancy and Position in Saccharomyces cerevisiae

Gossett, Andrea J., Lieb, Jason D., Rando, Oliver J.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.60 MB

english, 2012

13

A SEL1L Mutation Links a Canine Progressive Early-Onset Cerebellar Ataxia to the Endoplasmic Reticulum–Associated Protein Degradation (ERAD) Machinery

Kyöstilä, Kaisa, Cizinauskas, Sigitas, Seppälä, Eija H., Suhonen, Esko, Jeserevics, Janis, Sukura, Antti, Syrjä, Pernilla, Lohi, Hannes, Leeb, Tosso

Journal:

Year:

2012

Language:

english

File:

PDF, 2.07 MB

english, 2012

14

Gustatory Perception and Fat Body Energy Metabolism Are Jointly Affected by Vitellogenin and Juvenile Hormone in Honey Bees

Wang, Ying, Brent, Colin S., Fennern, Erin, Amdam, Gro V., Rulifson, Eric

Journal:

Year:

2012

Language:

english

File:

PDF, 392 KB

english, 2012

15

Interplay between Synaptonemal Complex, Homologous Recombination, and Centromeres during Mammalian Meiosis

Qiao, Huanyu, Chen, Jefferson K., Reynolds, April, Höög, Christer, Paddy, Michael, Hunter, Neil, Hawley, R. Scott

Journal:

Year:

2012

Language:

english

File:

PDF, 5.78 MB

english, 2012

16

Patterns of Evolutionary Conservation of Essential Genes Correlate with Their Compensability

Bergmiller, Tobias, Ackermann, Martin, Silander, Olin K., Matic, Ivan

Journal:

Year:

2012

Language:

english

File:

PDF, 2.61 MB

english, 2012

17

Decreased Mitochondrial DNA Mutagenesis in Human Colorectal Cancer

Ericson, Nolan G., Kulawiec, Mariola, Vermulst, Marc, Sheahan, Kieran, O'Sullivan, Jacintha, Salk, Jesse J., Bielas, Jason H., Rosenberg, Susan M.

Journal:

Year:

2012

Language:

english

File:

PDF, 547 KB

english, 2012

18

TERRA Promotes Telomere Shortening through Exonuclease 1–Mediated Resection of Chromosome Ends

Pfeiffer, Verena, Lingner, Joachim, Marcand, Stephane

Journal:

Year:

2012

Language:

english

File:

PDF, 4.03 MB

english, 2012

19

Protective Coupling of Mitochondrial Function and Protein Synthesis via the eIF2α Kinase GCN-2

Baker, Brooke M., Nargund, Amrita M., Sun, Tiffany, Haynes, Cole M., Larsson, Nils-Göran

Journal:

Year:

2012

Language:

english

File:

PDF, 2.24 MB

english, 2012

20

Found: The Elusive ANTAR Transcription Antiterminator

Stewart, Valley, van Tilbeurgh, Herman, Burkholder, William F.

Journal:

Year:

2012

Language:

english

File:

PDF, 252 KB

english, 2012

21

Global Regulatory Functions of the Staphylococcus aureus Endoribonuclease III in Gene Expression

Lioliou, Efthimia, Sharma, Cynthia M., Caldelari, Isabelle, Helfer, Anne-Catherine, Fechter, Pierre, Vandenesch, François, Vogel, Jörg, Romby, Pascale, Hughes, Diarmaid

Journal:

Year:

2012

Language:

english

File:

PDF, 3.33 MB

english, 2012

22

Gene Expression Profiles in Parkinson Disease Prefrontal Cortex Implicate FOXO1 and Genes under Its Transcriptional Regulation

Dumitriu, Alexandra, Latourelle, Jeanne C., Hadzi, Tiffany C., Pankratz, Nathan, Garza, Dan, Miller, John P., Vance, Jeffery M., Foroud, Tatiana, Beach, Thomas G., Myers, Richard H., Gibson, Greg

Journal:

Year:

2012

Language:

english

File:

PDF, 469 KB

english, 2012

23

Genome-Wide Identification of Ampicillin Resistance Determinants in Enterococcus faecium

Zhang, Xinglin, Paganelli, Fernanda L., Bierschenk, Damien, Kuipers, Annemarie, Bonten, Marc J. M., Willems, Rob J. L., van Schaik, Willem, Hughes, Diarmaid

Journal:

Year:

2012

Language:

english

File:

PDF, 925 KB

english, 2012

24

Mimetic Butterflies Introgress to Impress

Kronforst, Marcus R., Barsh, Gregory S.

Journal:

Year:

2012

Language:

english

File:

PDF, 198 KB

english, 2012

25

Stretching the Rules: Monocentric Chromosomes with Multiple Centromere Domains

Neumann, Pavel, Navrátilová, Alice, Schroeder-Reiter, Elizabeth, Koblížková, Andrea, Steinbauerová, Veronika, Chocholová, Eva, Novák, Petr, Wanner, Gerhard, Macas, Jiří, Sullivan, Beth A.

Journal:

Year:

2012

Language:

english

File:

PDF, 920 KB

english, 2012

26

Rumors of Its Disassembly Have Been Greatly Exaggerated: The Secret Life of the Synaptonemal Complex at the Centromeres

Takeo, Satomi, Hawley, R. Scott, Copenhaver, Gregory P.

Journal:

Year:

2012

Language:

english

File:

PDF, 116 KB

english, 2012

27

Fuzzy Tandem Repeats Containing p53 Response Elements May Define Species-Specific p53 Target Genes

Simeonova, Iva, Lejour, Vincent, Bardot, Boris, Bouarich-Bourimi, Rachida, Morin, Aurélie, Fang, Ming, Charbonnier, Laure, Toledo, Franck, Barsh, Gregory S.

Journal:

Year:

2012

Language:

english

File:

PDF, 771 KB

english, 2012

28

Parallel Evolution of Auditory Genes for Echolocation in Bats and Toothed Whales

Shen, Yong-Yi, Liang, Lu, Li, Gui-Sheng, Murphy, Robert W., Zhang, Ya-Ping, Zhang, Jianzhi

Journal:

Year:

2012

Language:

english

File:

PDF, 588 KB

english, 2012

29

In Vivo Control of CpG and Non-CpG DNA Methylation by DNA Methyltransferases

Arand, Julia, Spieler, David, Karius, Tommy, Branco, Miguel R., Meilinger, Daniela, Meissner, Alexander, Jenuwein, Thomas, Xu, Guoliang, Leonhardt, Heinrich, Wolf, Verena, Walter, Jörn, Schübeler, Dir

Journal:

Year:

2012

Language:

english

File:

PDF, 1.38 MB

english, 2012

30

MicroRNA93 Regulates Proliferation and Differentiation of Normal and Malignant Breast Stem Cells

Liu, Suling, Patel, Shivani H., Ginestier, Christophe, Ibarra, Ingrid, Martin-Trevino, Rachel, Bai, Shoumin, McDermott, Sean P., Shang, Li, Ke, Jia, Ou, Sing J., Heath, Amber, Zhang, Kevin J., Korkaya

Journal:

Year:

2012

Language:

english

File:

PDF, 2.11 MB

english, 2012

31

Preferential Genome Targeting of the CBP Co-Activator by Rel and Smad Proteins in Early Drosophila melanogaster Embryos

Holmqvist, Per-Henrik, Boija, Ann, Philip, Philge, Crona, Filip, Stenberg, Per, Mannervik, Mattias, Perrimon, Norbert

Journal:

Year:

2012

Language:

english

File:

PDF, 1.29 MB

english, 2012

32

Genome-Wide Location Analysis Reveals Distinct Transcriptional Circuitry by Paralogous Regulators Foxa1 and Foxa2

Bochkis, Irina M., Schug, Jonathan, Ye, Diana Z., Kurinna, Svitlana, Stratton, Sabrina A., Barton, Michelle C., Kaestner, Klaus H., Snyder, Michael

Journal:

Year:

2012

Language:

english

File:

PDF, 1.14 MB

english, 2012

33

The NSL Complex Regulates Housekeeping Genes in Drosophila

Lam, Kin Chung, Mühlpfordt, Friederike, Vaquerizas, Juan M., Raja, Sunil Jayaramaiah, Holz, Herbert, Luscombe, Nicholas M., Manke, Thomas, Akhtar, Asifa, Carroll, Jason

Journal:

Year:

2012

Language:

english

File:

PDF, 2.38 MB

english, 2012

34

Genome-Wide Functional Profiling Identifies Genes and Processes Important for Zinc-Limited Growth of Saccharomyces cerevisiae

North, Matthew, Steffen, Janet, Loguinov, Alex V., Zimmerman, Ginelle R., Vulpe, Chris D., Eide, David J., Philpott, Caroline C.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.61 MB

english, 2012

35

Brain Expression Genome-Wide Association Study (eGWAS) Identifies Human Disease-Associated Variants

Zou, Fanggeng, Chai, High Seng, Younkin, Curtis S., Allen, Mariet, Crook, Julia, Pankratz, V. Shane, Carrasquillo, Minerva M., Rowley, Christopher N., Nair, Asha A., Middha, Sumit, Maharjan, Sooraj, N

Journal:

Year:

2012

Language:

english

File:

PDF, 430 KB

english, 2012

36

Genetic Variants on Chromosome 1q41 Influence Ocular Axial Length and High Myopia

Fan, Qiao, Barathi, Veluchamy A., Cheng, Ching-Yu, Zhou, Xin, Meguro, Akira, Nakata, Isao, Khor, Chiea-Chuen, Goh, Liang-Kee, Li, Yi-Ju, Lim, Wan'e, Ho, Candice E. H., Hawthorne, Felicia, Zheng, Yingf

Journal:

Year:

2012

Language:

english

File:

PDF, 2.80 MB

english, 2012

37

Polymorphisms in the Mitochondrial Ribosome Recycling Factor EF-G2mt/MEF2 Compromise Cell Respiratory Function and Increase Atorvastatin Toxicity

Callegari, Sylvie, Gregory, Philip A., Sykes, Matthew J., Bellon, Jennifer, Andrews, Stuart, McKinnon, Ross A., de Barros Lopes, Miguel A., Tomita-Takeuchi, Nono

Journal:

Year:

2012

Language:

english

File:

PDF, 1.67 MB

english, 2012

38

G Protein Activation without a GEF in the Plant Kingdom

Urano, Daisuke, Jones, Janice C., Wang, Hao, Matthews, Melissa, Bradford, William, Bennetzen, Jeffrey L., Jones, Alan M., Malik, Harmit S.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.87 MB

english, 2012

39

Tipping the Balance in the Powerhouse of the Cell to “Protect” Colorectal Cancer

Kidane, Dawit, Sweasy, Joann B., Rosenberg, Susan M.

Journal:

Year:

2012

Language:

english

File:

PDF, 173 KB

english, 2012

40

Attenuation of Notch and Hedgehog Signaling Is Required for Fate Specification in the Spinal Cord

Huang, Peng, Xiong, Fengzhu, Megason, Sean G., Schier, Alexander F., Mullins, Mary C.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.92 MB

english, 2012

41

Geographic Differences in Genetic Susceptibility to IgA Nephropathy: GWAS Replication Study and Geospatial Risk Analysis

Kiryluk, Krzysztof, Li, Yifu, Sanna-Cherchi, Simone, Rohanizadegan, Mersedeh, Suzuki, Hitoshi, Eitner, Frank, Snyder, Holly J., Choi, Murim, Hou, Ping, Scolari, Francesco, Izzi, Claudia, Gigante, Madd

Journal:

Year:

2012

Language:

english

File:

PDF, 1.24 MB

english, 2012

42

An Engineering Approach to Extending Lifespan in C. elegans

Sagi, Dror, Kim, Stuart K., Ruvkun, Gary

Journal:

Year:

2012

Language:

english

File:

PDF, 1.73 MB

english, 2012

43

Incompatibility and Competitive Exclusion of Genomic Segments between Sibling Drosophila Species

Fang, Shu, Yukilevich, Roman, Chen, Ying, Turissini, David A., Zeng, Kai, Boussy, Ian A., Wu, Chung-I., Akey, Joshua M.

Journal:

Year:

2012

Language:

english

File:

PDF, 339 KB

english, 2012

44

A Broad Requirement for TLS Polymerases η and κ, and Interacting Sumoylation and Nuclear Pore Proteins, in Lesion Bypass during C. elegans Embryogenesis

Roerink, Sophie F., Koole, Wouter, Stapel, L. Carine, Romeijn, Ron J., Tijsterman, Marcel, Jinks-Robertson, Sue

Journal:

Year:

2012

Language:

english

File:

PDF, 2.86 MB

english, 2012

45

The Rad4TopBP1 ATR-Activation Domain Functions in G1/S Phase in a Chromatin-Dependent Manner

Lin, Su-Jiun, Wardlaw, Christopher P., Morishita, Takashi, Miyabe, Izumi, Chahwan, Charly, Caspari, Thomas, Schmidt, Ulrike, Carr, Antony M., Garcia, Valerie, Jinks-Robertson, Sue

Journal:

Year:

2012

Language:

english

File:

PDF, 2.69 MB

english, 2012

46

The Rose-comb Mutation in Chickens Constitutes a Structural Rearrangement Causing Both Altered Comb Morphology and Defective Sperm Motility

Imsland, Freyja, Feng, Chungang, Boije, Henrik, Bed'hom, Bertrand, Fillon, Valérie, Dorshorst, Ben, Rubin, Carl-Johan, Liu, Ranran, Gao, Yu, Gu, Xiaorong, Wang, Yanqiang, Gourichon, David, Zody, Micha

Journal:

Year:

2012

Language:

english

File:

PDF, 985 KB

english, 2012

47

Limits to the Rate of Adaptive Substitution in Sexual Populations

Weissman, Daniel B., Barton, Nicholas H., McVean, Gil

Journal:

Year:

2012

Language:

english

File:

PDF, 1.36 MB

english, 2012

48

sox9b Is a Key Regulator of Pancreaticobiliary Ductal System Development

Delous, Marion, Yin, Chunyue, Shin, Donghun, Ninov, Nikolay, Debrito Carten, Juliana, Pan, Luyuan, Ma, Taylur P., Farber, Steven A., Moens, Cecilia B., Stainier, Didier Y. R., Mullins, Mary C.

Journal:

Year:

2012

Language:

english

File:

PDF, 5.96 MB

english, 2012

49

Base-Pair Resolution DNA Methylation Sequencing Reveals Profoundly Divergent Epigenetic Landscapes in Acute Myeloid Leukemia

Akalin, Altuna, Garrett-Bakelman, Francine E., Kormaksson, Matthias, Busuttil, Jennifer, Zhang, Lu, Khrebtukova, Irina, Milne, Thomas A., Huang, Yongsheng, Biswas, Debabrata, Hess, Jay L., Allis, C. D

Journal:

Year:

2012

Language:

english

File:

PDF, 1.29 MB

english, 2012

50

Diverse CRISPRs Evolving in Human Microbiomes

Rho, Mina, Wu, Yu-Wei, Tang, Haixu, Doak, Thomas G., Ye, Yuzhen, Guttman, David S.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.04 MB

english, 2012

51

RNA Methylation by the MIS Complex Regulates a Cell Fate Decision in Yeast

Agarwala, Sudeep D., Blitzblau, Hannah G., Hochwagen, Andreas, Fink, Gerald R., Lichten, Michael

Journal:

Year:

2012

Language:

english

File:

PDF, 2.88 MB

english, 2012

52

Divergence of the Yeast Transcription Factor FZF1 Affects Sulfite Resistance

Engle, Elizabeth K., Fay, Justin C., Malik, Harmit S.

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Year:

2012

Language:

english

File:

PDF, 665 KB

english, 2012

53

Cohesin Proteins Promote Ribosomal RNA Production and Protein Translation in Yeast and Human Cells

Bose, Tania, Lee, Kenneth K., Lu, Shuai, Xu, Baoshan, Harris, Bethany, Slaughter, Brian, Unruh, Jay, Garrett, Alexander, McDowell, William, Box, Andrew, Li, Hua, Peak, Allison, Ramachandran, Sree, Sei

Journal:

Year:

2012

Language:

english

File:

PDF, 3.30 MB

english, 2012

54

Uracil-Containing DNA in Drosophila: Stability, Stage-Specific Accumulation, and Developmental Involvement

Muha, Villő, Horváth, András, Békési, Angéla, Pukáncsik, Mária, Hodoscsek, Barbara, Merényi, Gábor, Róna, Gergely, Batki, Júlia, Kiss, István, Jankovics, Ferenc, Vilmos, Péter, Erdélyi, Miklós, Vértes

Journal:

Year:

2012

Language:

english

File:

PDF, 1.67 MB

english, 2012

55

Dual-Level Regulation of ACC Synthase Activity by MPK3/MPK6 Cascade and Its Downstream WRKY Transcription Factor during Ethylene Induction in Arabidopsis

Li, Guojing, Meng, Xiangzong, Wang, Ruigang, Mao, Guohong, Han, Ling, Liu, Yidong, Zhang, Shuqun, Kieber, Joseph

Journal:

Year:

2012

Language:

english

File:

PDF, 1.03 MB

english, 2012

56

A Mouse Model of Acrodermatitis Enteropathica: Loss of Intestine Zinc Transporter ZIP4 (Slc39a4) Disrupts the Stem Cell Niche and Intestine Integrity

Geiser, Jim, Venken, Koen J. T., De Lisle, Robert C., Andrews, Glen K., Küry, Sébastien

Journal:

Year:

2012

Language:

english

File:

PDF, 4.39 MB

english, 2012

57

Quantifying the Adaptive Potential of an Antibiotic Resistance Enzyme

Schenk, Martijn F., Szendro, Ivan G., Krug, Joachim, de Visser, J. Arjan G. M., Hughes, Diarmaid

Journal:

Year:

2012

Language:

english

File:

PDF, 581 KB

english, 2012

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