Volume 97; Issue 10

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Proceedings of the National Academy of Sciences
Volume 97; Issue 10

Proceedings of the National Academy of Sciences

Volume 97; Issue 10

1

A universal scaling law between gray matter and white matter of cerebral cortex

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 137 KB

english, 2000

2

Crystal structure of a Staphylococcus aureus protein A domain complexed with the Fab fragment of a human IgM antibody: Structural basis for recognition of B-cell receptors and superantigen activity

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 549 KB

english, 2000

3

The phylogeny of closely related species as revealed by the genealogy of a speciation gene, Odysseus

Ting, C.-T., Tsaur, S.-C., Wu, C.-I

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 87 KB

english, 2000

4

Coexistence of linear zones and pinwheels within orientation maps in cat visual cortex

Shmuel, A., Grinvald, A.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 939 KB

english, 2000

5

Computation, prediction, and experimental tests of fitness for bacteriophage T7 mutants with permuted genomes

Endy, D., You, L., Yin, J., Molineux, I. J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 353 KB

english, 2000

6

Peptide interfacial adsorption is kinetically limited by the thermodynamic stability of self association

Middelberg, A. P. J., Radke, C. J., Blanch, H. W.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 139 KB

english, 2000

7

Early-life exposure to endotoxin alters hypothalamic-pituitary-adrenal function and predisposition to inflammation

Shanks, N., Windle, R. J., Perks, P. A., Harbuz, M. S., Jessop, D. S., Ingram, C. D., Lightman, S. L.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 168 KB

english, 2000

8

Separation of the glucose-stimulated cytoplasmic and mitochondrial NAD(P)H responses in pancreatic islet beta cells

Patterson, G. H., Knobel, S. M., Arkhammar, P., Thastrup, O., Piston, D. W.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 131 KB

english, 2000

9

The Escherichia coli MG1655 in silico metabolic genotype: Its definition, characteristics, and capabilities

Edwards, J. S., Palsson, B. O.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 348 KB

english, 2000

10

Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a

Ramsahoye, B. H., Biniszkiewicz, D., Lyko, F., Clark, V., Bird, A. P., Jaenisch, R.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 329 KB

english, 2000

11

Signals transducers and activators of transcription (STAT)-induced STAT inhibitor-1 (SSI-1)/suppressor of cytokine signaling-1 (SOCS-1) suppresses tumor necrosis factor alpha -induced cell death in fibroblasts

Morita, Y., Naka, T., Kawazoe, Y., Fujimoto, M., Narazaki, M., Nakagawa, R., Fukuyama, H., Nagata, S., Kishimoto, T.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 150 KB

english, 2000

12

D-beta -Hydroxybutyrate protects neurons in models of Alzheimer's and Parkinson's disease

Kashiwaya, Y., Takeshima, T., Mori, N., Nakashima, K., Clarke, K., Veech, R. L.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 1.20 MB

english, 2000

13

Potent and nontoxic antisense oligonucleotides containing locked nucleic acids

Wahlestedt, C., Salmi, P., Good, L., Kela, J., Johnsson, T., Hokfelt, T., Broberger, C., Porreca, F., Lai, J., Ren, K., Ossipov, M., Koshkin, A., Jakobsen, N., Skouv, J., Oerum, H., Jacobsen, M. H., W

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 486 KB

english, 2000

14

Rapid evolution in plant chitinases: Molecular targets of selection in plant-pathogen coevolution

Bishop, J. G., Dean, A. M., Mitchell-Olds, T.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 463 KB

english, 2000

15

A deletion in a photoreceptor-specific nuclear receptor mRNA causes retinal degeneration in the rd7 mouse

Akhmedov, N. B., Piriev, N. I., Chang, B., Rapoport, A. L., Hawes, N. L., Nishina, P. M., Nusinowitz, S., Heckenlively, J. R., Roderick, T. H., Kozak, C. A., Danciger, M., Davisson, M. T., Farber, D.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 508 KB

english, 2000

16

Microcolumns in the cerebral cortex

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 443 KB

english, 2000

17

Gene therapy for the hemoglobin disorders: Past, present, and future

Persons, D. A., Nienhuis, A. W.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 94 KB

english, 2000

18

(4-Aminomethyl)phenylguanidine derivatives as nonpeptidic highly selective inhibitors of human urokinase

Sperl, S., Jacob, U., Arroyo de Prada, N., Sturzebecher, J., Wilhelm, O. G., Bode, W., Magdolen, V., Huber, R., Moroder, L.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 291 KB

english, 2000

19

Ultrasensitive detection of pathological prion protein aggregates by dual-color scanning for intensely fluorescent targets

Bieschke, J., Giese, A., Schulz-Schaeffer, W., Zerr, I., Poser, S., Eigen, M., Kretzschmar, H.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 383 KB

english, 2000

20

Estrogen receptor specificity in the regulation of skeletal growth and maturation in male mice

Vidal, O., Lindberg, M. K., Hollberg, K., Baylink, D. J., Andersson, G., Lubahn, D. B., Mohan, S., Gustafsson, J.-A., Ohlsson, C.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 169 KB

english, 2000

21

Exceptionally potent inhibitors of fatty acid amide hydrolase: The enzyme responsible for degradation of endogenous oleamide and anandamide

Boger, D. L., Sato, H., Lerner, A. E., Hedrick, M. P., Fecik, R. A., Miyauchi, H., Wilkie, G. D., Austin, B. J., Patricelli, M. P., Cravatt, B. F.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 154 KB

english, 2000

22

Gene content phylogeny of herpesviruses

Montague, M. G., Hutchison, C. A.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 629 KB

english, 2000

23

Sodium channel Nav1.6 is localized at nodes of Ranvier, dendrites, and synapses

Caldwell, J. H., Schaller, K. L., Lasher, R. S., Peles, E., Levinson, S. R.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 573 KB

english, 2000

24

AIS is an oncogene amplified in squamous cell carcinoma

Hibi, K., Trink, B., Patturajan, M., Westra, W. H., Caballero, O. L., Hill, D. E., Ratovitski, E. A., Jen, J., Sidransky, D.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 267 KB

english, 2000

25

A highly digestible sorghum mutant cultivar exhibits a unique folded structure of endosperm protein bodies

Oria, M. P., Hamaker, B. R., Axtell, J. D., Huang, C.-P.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 572 KB

english, 2000

26

Production of infectious bovine papillomavirus from cloned viral DNA by using an organotypic raft/xenograft technique

McBride, A. A., Dlugosz, A., Baker, C. C.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 286 KB

english, 2000

27

Assembly of tau protein into Alzheimer paired helical filaments depends on a local sequence motif (306VQIVYK311) forming beta structure

von Bergen, M., Friedhoff, P., Biernat, J., Heberle, J., Mandelkow, E.-M., Mandelkow, E.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 262 KB

english, 2000

28

c-Abl is required for development and optimal cell proliferation in the context of p53 deficiency

Whang, Y. E., Tran, C., Henderson, C., Syljuasen, R. G., Rozengurt, N., McBride, W. H., Sawyers, C. L.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 284 KB

english, 2000

29

Supramolecular complexes in photosynthetic bacteria

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 198 KB

english, 2000

30

Binding of bisubstrate analog promotes large structural changes in the unregulated catalytic trimer of aspartate transcarbamoylase: Implications for allosteric regulation

Endrizzi, J. A., Beernink, P. T., Alber, T., Schachman, H. K.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 543 KB

english, 2000

31

Staphylococcus aureus sortase mutants defective in the display of surface proteins and in the pathogenesis of animal infections

Mazmanian, S. K., Liu, G., Jensen, E. R., Lenoy, E., Schneewind, O.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 264 KB

english, 2000

32

Long-term kinetics of T cell production in HIV-infected subjects treated with highly active antiretroviral therapy

Fleury, S., Rizzardi, G. P., Chapuis, A., Tambussi, G., Knabenhans, C., Simeoni, E., Meuwly, J.-Y., Corpataux, J.-M., Lazzarin, A., Miedema, F., Pantaleo, G.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 157 KB

english, 2000

33

Noninvasive measurement of gene expression in skeletal muscle

Walter, G., Barton, E. R., Sweeney, H. L.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 112 KB

english, 2000

34

Neonatal lead exposure impairs development of rodent barrel field cortex

Wilson, M. A., Johnston, M. V., Goldstein, G. W., Blue, M. E.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 349 KB

english, 2000

35

Detection and selective dissociation of intact ribosomes in a mass spectrometer

Rostom, A. A., Fucini, P., Benjamin, D. R., Juenemann, R., Nierhaus, K. H., Hartl, F. U., Dobson, C. M., Robinson, C. V.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 122 KB

english, 2000

36

Accumulation of protease-resistant prion protein (PrP) and apoptosis of cerebellar granule cells in transgenic mice expressing a PrP insertional mutation

Chiesa, R., Drisaldi, B., Quaglio, E., Migheli, A., Piccardo, P., Ghetti, B., Harris, D. A.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 358 KB

english, 2000

37

Behavioral alterations associated with apoptosis and down-regulation of presenilin 1 in the brains of p53-deficient mice

Amson, R., Lassalle, J.-M., Halley, H., Prieur, S., Lethrosne, F., Roperch, J.-P., Israeli, D., Gendron, M.-C., Duyckaerts, C., Checler, F., Dausset, J., Cohen, D., Oren, M., Telerman, A.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 227 KB

english, 2000

38

Aberrant B cell receptor signaling from B29 (Igbeta , CD79b) gene mutations of chronic lymphocytic leukemia B cells

Gordon, M. S., Kato, R. M., Lansigan, F., Thompson, A. A., Wall, R., Rawlings, D. J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 296 KB

english, 2000

39

5-Lipoxygenase is phosphorylated by p38 kinase-dependent MAPKAP kinases

Werz, O., Klemm, J., Samuelsson, B., Radmark, O.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 231 KB

english, 2000

40

Uracil-DNA glycosylase-DNA substrate and product structures: Conformational strain promotes catalytic efficiency by coupled stereoelectronic effects

Parikh, S. S., Walcher, G., Jones, G. D., Slupphaug, G., Krokan, H. E., Blackburn, G. M., Tainer, J. A.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 409 KB

english, 2000

41

Cell signaling pathways as control modules: Complexity for simplicity?

Lauffenburger, D. A.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 59 KB

english, 2000

42

Cyclin A activates the DNA polymerase delta -dependent elongation machinery in vitro: A parvovirus DNA replication model

Bashir, T., Horlein, R., Rommelaere, J., Willwand, K.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 247 KB

english, 2000

43

Selective disruption of protein aggregation by cyclodextrin dimers

Leung, D. K., Yang, Z., Breslow, R.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 234 KB

english, 2000

44

MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration

Xia, Y., Makris, C., Su, B., Li, E., Yang, J., Nemerow, G. R., Karin, M.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 390 KB

english, 2000

45

Engineering the largest RNA virus genome as an infectious bacterial artificial chromosome

Almazan, F., Gonzalez, J. M., Penzes, Z., Izeta, A., Calvo, E., Plana-Duran, J., Enjuanes, L.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 255 KB

english, 2000

46

Why are angles misperceived?

Nundy, S., Lotto, B., Coppola, D., Shimpi, A., Purves, D.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 771 KB

english, 2000

47

Xenopus Kielin: A dorsalizing factor containing multiple chordin-type repeats secreted from the embryonic midline

Matsui, M., Mizuseki, K., Nakatani, J., Nakanishi, S., Sasai, Y.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 351 KB

english, 2000

48

Automated parallel DNA sequencing on multiple channel microchips

Liu, S., Ren, H., Gao, Q., Roach, D. J., Loder, R. T., Armstrong, T. M., Mao, Q., Blaga, I., Barker, D. L., Jovanovich, S. B.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 429 KB

english, 2000

49

Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-gamma target genes

Ouchi, T., Lee, S. W., Ouchi, M., Aaronson, S. A., Horvath, C. M.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 174 KB

english, 2000

50

Distinct roles of the NH2- and COOH-terminal domains of the protein inhibitor of activated signal transducer and activator of transcription (STAT) 1 (PIAS1) in cytokine-induced PIAS1-Stat1 interaction

Liao, J., Fu, Y., Shuai, K.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 249 KB

english, 2000

51

Glutathione synthesis is essential for mouse development but not for cell growth in culture

Shi, Z.-Z., Osei-Frimpong, J., Kala, G., Kala, S. V., Barrios, R. J., Habib, G. M., Lukin, D. J., Danney, C. M., Matzuk, M. M., Lieberman, M. W.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 365 KB

english, 2000

52

Deficits in memory and motor performance in synaptotagmin IV mutant mice

Ferguson, G. D., Anagnostaras, S. G., Silva, A. J., Herschman, H. R.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 159 KB

english, 2000

53

Uncompensated polyuria in a mouse model of Bartter's syndrome

Takahashi, N., Chernavvsky, D. R., Gomez, R. A., Igarashi, P., Gitelman, H. J., Smithies, O.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 272 KB

english, 2000

54

10.1073/pnas.97.10.5679-b

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 345 KB

english, 2000

55

5-Methylcytosine-DNA glycosylase activity is present in a cloned G/T mismatch DNA glycosylase associated with the chicken embryo DNA demethylation complex

Zhu, B., Zheng, Y., Hess, D., Angliker, H., Schwarz, S., Siegmann, M., Thiry, S., Jost, J.-P.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 188 KB

english, 2000

56

Molecular basis for a link between complement and the vascular complications of diabetes

Acosta, J., Hettinga, J., Fluckiger, R., Krumrei, N., Goldfine, A., Angarita, L., Halperin, J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 274 KB

english, 2000

57

Direct nitric oxide signal transduction via nitrosylation of iron-sulfur centers in the SoxR transcription activator

Ding, H., Demple, B.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 161 KB

english, 2000

58

DNA polymerase active site is highly mutable: Evolutionary consequences

Patel, P. H., Loeb, L. A.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 248 KB

english, 2000

59

A neuronal beta subunit (KCNMB4) makes the large conductance, voltage- and Ca2+-activated K+ channel resistant to charybdotoxin and iberiotoxin

Meera, P., Wallner, M., Toro, L.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 381 KB

english, 2000

60

Inhibition of calcium/calmodulin kinase II alpha subunit expression results in epileptiform activity in cultured hippocampal neurons

Churn, S. B., Sombati, S., Jakoi, E. R., Severt, L., DeLorenzo, R. J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 753 KB

english, 2000

61

Myogenic stem cell function is impaired in mice lacking the forkhead/winged helix protein MNF

Garry, D. J., Meeson, A., Elterman, J., Zhao, Y., Yang, P., Bassel-Duby, R., Williams, R. S.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 552 KB

english, 2000

62

Critical contribution of liver natural killer T cells to a murine model of hepatitis

Takeda, K., Hayakawa, Y., Van Kaer, L., Matsuda, H., Yagita, H., Okumura, K.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 207 KB

english, 2000

63

Misactivated amino acids translocate at similar rates across surface of a tRNA synthetase

Nomanbhoy, T. K., Schimmel, P. R.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 104 KB

english, 2000

64

The myosin motor, Myo4p, binds Ash1 mRNA via the adapter protein, She3p

Takizawa, P. A., Vale, R. D.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 256 KB

english, 2000

65

Cortical cell death induced by IL-1 is mediated via actions in the hypothalamus of the rat

Allan, S. M., Parker, L. C., Collins, B., Davies, R., Luheshi, G. N., Rothwell, N. J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 185 KB

english, 2000

66

Sid4p is required to localize components of the septation initiation pathway to the spindle pole body in fission yeast

Chang, L., Gould, K. L.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 333 KB

english, 2000

67

The tomato ethylene receptors NR and LeETR4 are negative regulators of ethylene response and exhibit functional compensation within a multigene family

Tieman, D. M., Taylor, M. G., Ciardi, J. A., Klee, H. J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 337 KB

english, 2000

68

Sortase, a universal target for therapeutic agents against Gram-positive bacteria?

Cossart, P., Jonquieres, R.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 194 KB

english, 2000

69

Chromosomal breakage-fusion-bridge events cause genetic intratumor heterogeneity

Gisselsson, D., Pettersson, L., Hoglund, M., Heidenblad, M., Gorunova, L., Wiegant, J., Mertens, F., Dal Cin, P., Mitelman, F., Mandahl, N.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 424 KB

english, 2000

70

Rescue of dystrophin expression in mdx mouse muscle by RNA/DNA oligonucleotides

Rando, T. A., Disatnik, M.-H., Zhou, L. Z.-H.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 407 KB

english, 2000

71

Epithelial and endothelial expression of the green fluorescent protein reporter gene under the control of bovine prion protein (PrP) gene regulatory sequences in transgenic mice

Lemaire-Vieille, C., Schulze, T., Podevin-Dimster, V., Follet, J., Bailly, Y., Blanquet-Grossard, F., Decavel, J.-P., Heinen, E., Cesbron, J.-Y.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 385 KB

english, 2000

72

Inverse radiation dose-rate effects on somatic and germ-line mutations and DNA damage rates

Vilenchik, M. M., Knudson, A. G.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 107 KB

english, 2000

73

Increased IGF-II protein affects p57kip2 expression in vivo and in vitro: Implications for Beckwith-Wiedemann syndrome

Grandjean, V., Smith, J., Schofield, P. N., Ferguson-Smith, A. C.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 212 KB

english, 2000

74

A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5

Dragic, T., Trkola, A., Thompson, D. A. D., Cormier, E. G., Kajumo, F. A., Maxwell, E., Lin, S. W., Ying, W., Smith, S. O., Sakmar, T. P., Moore, J. P.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 274 KB

english, 2000

75

The fourth chromosome of Drosophila melanogaster: Interspersed euchromatic and heterochromatic domains

Sun, F.-L., Cuaycong, M. H., Craig, C. A., Wallrath, L. L., Locke, J., Elgin, S. C. R.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 459 KB

english, 2000

76

National security and scientific communication

Panofsky, W. K. H.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 50 KB

english, 2000

77

Nuclear structure in normal and Bloom syndrome cells

Yankiwski, V., Marciniak, R. A., Guarente, L., Neff, N. F.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 416 KB

english, 2000

78

The making of infectious viral RNA: No size limit in sight

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 60 KB

english, 2000

79

An autologous oral DNA vaccine protects against murine melanoma

Xiang, R., Lode, H. N., Chao, T.-H., Ruehlmann, J. M., Dolman, C. S., Rodriguez, F., Whitton, J. L., Overwijk, W. W., Restifo, N. P., Reisfeld, R. A.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 169 KB

english, 2000

80

Somatic polyploidization and cellular proliferation drive body size evolution in nematodes

Flemming, A. J., Shen, Z.-Z., Cunha, A., Emmons, S. W., Leroi, A. M.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 248 KB

english, 2000

81

Description of microcolumnar ensembles in association cortex and their disruption in Alzheimer and Lewy body dementias

Buldyrev, S. V., Cruz, L., Gomez-Isla, T., Gomez-Tortosa, E., Havlin, S., Le, R., Stanley, H. E., Urbanc, B., Hyman, B. T.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 526 KB

english, 2000

82

LexA chimeras reveal the function of Drosophila Fos as a context-dependent transcriptional activator

Szuts, D., Bienz, M.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 177 KB

english, 2000

83

A functional R domain from cystic fibrosis transmembrane conductance regulator is predominantly unstructured in solution

Ostedgaard, L. S., Baldursson, O., Vermeer, D. W., Welsh, M. J., Robertson, A. D.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 226 KB

english, 2000

84

New patterns of centrifugally driven thermal convection

Jaletzky, M., Busse, F. H.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 504 KB

english, 2000

85

Role of Rac in controlling the actin cytoskeleton and chemotaxis in motile cells

Chung, C. Y., Lee, S., Briscoe, C., Ellsworth, C., Firtel, R. A.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 215 KB

english, 2000

86

Characterization of PDZ-binding kinase, a mitotic kinase

Gaudet, S., Branton, D., Lue, R. A.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 313 KB

english, 2000

87

Preservation of myocardial beta -adrenergic receptor signaling delays the development of heart failure after myocardial infarction

White, D. C., Hata, J. A., Shah, A. S., Glower, D. D., Lefkowitz, R. J., Koch, W. J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 199 KB

english, 2000

88

Bepridil opens the regulatory N-terminal lobe of cardiac troponin C

Li, Y., Love, M. L., Putkey, J. A., Cohen, C.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 513 KB

english, 2000

89

A green fluorescent protein-reporter mammalian two-hybrid system with extrachromosomal maintenance of a prey expression plasmid: Application to interaction screening

Shioda, T., Andriole, S., Yahata, T., Isselbacher, K. J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 442 KB

english, 2000

90

NMR and mutagenesis evidence for an I domain allosteric site that regulates lymphocyte function-associated antigen 1 ligand binding

Huth, J. R., Olejniczak, E. T., Mendoza, R., Liang, H., Harris, E. A. S., Lupher, M. L., Wilson, A. E., Fesik, S. W., Staunton, D. E.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 520 KB

english, 2000

91

The role of members of the pertussis toxin-sensitive family of G proteins in coupling receptors to the activation of the G protein-gated inwardly rectifying potassium channel

Leaney, J. L., Tinker, A.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 171 KB

english, 2000

92

New Members and Foreign Associates Elected to the National Academy of Sciences on May 2, 2000. 60 New Members Chosen by the Academy

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 40 KB

english, 2000

93

The crystal structure of the Rev binding element of HIV-1 reveals novel base pairing and conformational variability

Hung, L.-W., Holbrook, E. L., Holbrook, S. R.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 355 KB

english, 2000

94

Single-molecule protein folding: Diffusion fluorescence resonance energy transfer studies of the denaturation of chymotrypsin inhibitor 2

Deniz, A. A., Laurence, T. A., Beligere, G. S., Dahan, M., Martin, A. B., Chemla, D. S., Dawson, P. E., Schultz, P. G., Weiss, S.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 133 KB

english, 2000

95

Establishment and persistence of photoperiodic memory in hamsters

Prendergast, B. J., Gorman, M. R., Zucker, I.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 158 KB

english, 2000

96

Blood glutathione synthesis rates in healthy adults receiving a sulfur amino acid-free diet

Lyons, J., Rauh-Pfeiffer, A., Yu, Y. M., Lu, X.-M., Zurakowski, D., Tompkins, R. G., Ajami, A. M., Young, V. R., Castillo, L.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 108 KB

english, 2000

97

An ancestral MADS-box gene duplication occurred before the divergence of plants and animals

Alvarez-Buylla, E. R., Pelaz, S., Liljegren, S. J., Gold, S. E., Burgeff, C., Ditta, G. S., Ribas de Pouplana, L., Martinez-Castilla, L., Yanofsky, M. F.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 519 KB

english, 2000

98

The long-range supraorganization of the bacterial photosynthetic unit: A key role for PufX

Frese, R. N., Olsen, J. D., Branvall, R., Westerhuis, W. H. J., Hunter, C. N., van Grondelle, R.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 330 KB

english, 2000

99

Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemic-induced apoptosis in a murine model of acute myocardial infarction

Kurrelmeyer, K. M., Michael, L. H., Baumgarten, G., Taffet, G. E., Peschon, J. J., Sivasubramanian, N., Entman, M. L., Mann, D. L.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 265 KB

english, 2000

100

Nitric oxide inhibits tumor necrosis factor-alpha -induced apoptosis by reducing the generation of ceramide

De Nadai, C., Sestili, P., Cantoni, O., Lievremont, J.-P., Sciorati, C., Barsacchi, R., Moncada, S., Meldolesi, J., Clementi, E.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 202 KB

english, 2000

101

In vitro evolution of a T cell receptor with high affinity for peptide/MHC

Holler, P. D., Holman, P. O., Shusta, E. V., O'Herrin, S., Wittrup, K. D., Kranz, D. M.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 241 KB

english, 2000

102

Gain of imprinting at chromosome 11p15: A pathogenetic mechanism identified in human hepatocarcinomas

Schwienbacher, C., Gramantieri, L., Scelfo, R., Veronese, A., Calin, G. A., Bolondi, L., Croce, C. M., Barbanti-Brodano, G., Negrini, M.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 198 KB

english, 2000

103

Conversion of a c type cytochrome to a b type that spontaneously forms in vitro from apo protein and heme: Implications for c type cytochrome biogenesis and folding

Tomlinson, E. J., Ferguson, S. J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 107 KB

english, 2000

104

The Gcd10p/Gcd14p complex is the essential two-subunit tRNA(1-methyladenosine) methyltransferase of Saccharomyces cerevisiae

Anderson, J., Phan, L., Hinnebusch, A. G.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 245 KB

english, 2000

105

Rapid transition in the structure of a coral reef community: The effects of coral bleaching and physical disturbance

Ostrander, G. K., Armstrong, K. M., Knobbe, E. T., Gerace, D., Scully, E. P.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 191 KB

english, 2000

106

Rapid regulated dense-core vesicle exocytosis requires the CAPS protein

Rupnik, M., Kreft, M., Sikdar, S. K., Grilc, S., Romih, R., Zupancic, G., Martin, T. F. J., Zorec, R.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 205 KB

english, 2000

107

Phosphorylation of protein kinase N by phosphoinositide-dependent protein kinase-1 mediates insulin signals to the actin cytoskeleton

Dong, L. Q., Landa, L. R., Wick, M. J., Zhu, L., Mukai, H., Ono, Y., Liu, F.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 230 KB

english, 2000

108

Mapping the interface between calmodulin and MARCKS-related protein by fluorescence spectroscopy

Ulrich, A., Schmitz, A. A. P., Braun, T., Yuan, T., Vogel, H. J., Vergeres, G.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 130 KB

english, 2000

109

Estimating the probability for a protein to have a new fold: A statistical computational model

Portugaly, E., Linial, M.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 144 KB

english, 2000

110

Growth of new brainstem connections in adult monkeys with massive sensory loss

Jain, N., Florence, S. L., Qi, H.-X., Kaas, J. H.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 388 KB

english, 2000

111

Preselection of retrovirally transduced bone marrow avoids subsequent stem cell gene silencing and age-dependent extinction of expression of human beta -globin in engrafted mice

Kalberer, C. P., Pawliuk, R., Imren, S., Bachelot, T., Takekoshi, K. J., Fabry, M., Eaves, C. J., London, I. M., Humphries, R. K., Leboulch, P.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 142 KB

english, 2000

112

Noise in neurons is message dependent

Cecchi, G. A., Sigman, M., Alonso, J.-M., Martinez, L., Chialvo, D. R., Magnasco, M. O.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 126 KB

english, 2000

113

Asparagine-proline sequence within membrane-spanning segment of SREBP triggers intramembrane cleavage by Site-2 protease

Ye, J., Dave, U. P., Grishin, N. V., Goldstein, J. L., Brown, M. S.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 337 KB

english, 2000

114

Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa

Camerer, E., Huang, W., Coughlin, S. R.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 148 KB

english, 2000

115

Novel gene conversion between X-Y homologues located in the nonrecombining region of the Y chromosome in Felidae (Mammalia)

Pecon Slattery, J., Sanner-Wachter, L., O'Brien, S. J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 377 KB

english, 2000

116

Permanence or change? The meaning of genetic variation

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 87 KB

english, 2000

117

Postgerminative growth and lipid catabolism in oilseeds lacking the glyoxylate cycle

Eastmond, P. J., Germain, V., Lange, P. R., Bryce, J. H., Smith, S. M., Graham, I. A.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 275 KB

english, 2000

118

Nas-Walras equilibria of a large economy

Minelli, E., Polemarchakis, H. M.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 94 KB

english, 2000

119

10.1073/pnas.97.10.5679-a

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 345 KB

english, 2000

120

10.1073/pnas.97.10.5679-c

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 345 KB

english, 2000

121

Correlation between the structure of the bacterial peptidoglycan monomer unit, the specificity of transpeptidation, and susceptibility to beta -lactams

van Heijenoort, J., Gutmann, L.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 66 KB

english, 2000

122

Density-dependent decline of host abundance resulting from a new infectious disease

Hochachka, W. M., Dhondt, A. A.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 141 KB

english, 2000

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