Volume 113

Regulatory Toxicology and Pharmacology

Volume 113

1

Development of improved QSAR models for predicting the outcome of the in vivo micronucleus genetic toxicity assay

Yoo, Jae Wook, Kruhlak, Naomi L., Landry, Curran, Cross, Kevin P., Sedykh, Alexander, Stavitskaya, Lidiya

Journal:

Regulatory Toxicology and Pharmacology

Year:

2020

File:

PDF, 1.10 MB

2020

2

Assessment of the inhibition risk of paris saponins, bioactive compounds from Paris polyphylla, on CYP and UGT enzymes via cocktail inhibition assays

Luo, Han, Xu, Yuan, Sun, Dongyi, Cheng, Yi, Sun, Zhenliang, Gao, Jing, Zhang, Yuanjin, Wang, Xin

Journal:

Regulatory Toxicology and Pharmacology

Year:

2020

Language:

english

File:

PDF, 1.31 MB

english, 2020

3

Chimeric hemagglutinin supra-seasonal universal influenza vaccine candidates administered sequentially by the intramuscular route are locally and systemically well-tolerated in rabbits

Destexhe, Ãric, Grosdidier, Ãmilie, Bouhraoua, AdÃ¨le, Thirion-Delalande, Catherine, Bouzya, Badiaa, Rouxel, Ronan N., Mallett, Corey P., Baumeister, Judith

Journal:

Regulatory Toxicology and Pharmacology

Year:

2020

Language:

english

File:

PDF, 1.65 MB

english, 2020

4

Recommendations for further revisions to improve the International Agency for Research on Cancer (IARC) Monograph program

Goodman, Julie E., Mayfield, David B., Becker, Richard A., Hartigan, Suzanne B., Erraguntla, Neeraja K.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2020

Language:

english

File:

PDF, 241 KB

english, 2020

5

âNaturalâ is not synonymous with âSafeâ: Toxicity of natural products alone and in combination with pharmaceutical agents

Gaston, Tyler E., Mendrick, Donna L., Paine, Mary F., Roe, Amy L., Yeung, Catherine K.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2020

Language:

english

File:

PDF, 440 KB

english, 2020

6

Evaluation of the sub-acute toxicity of Acacia catechu Willd seed extract in a Wistar albino rat model

Thangavelu, Lakshmi, Balusamy, Sri Renukadevi, Shanmugam, Rajeshkumar, Sivanesan, Senthilkumar, Devaraj, Ezhilarasan, Rajagopalan, Vijayaraghavan, Veeraiyan, Deepak Nallaswamy, Chellappan, Dinesh Kuma

Journal:

Regulatory Toxicology and Pharmacology

Year:

2020

File:

PDF, 1.42 MB

2020

7

Acute and repeated dose 28-day oral toxicity of Chrysobalanus icaco L. leaf aqueous extract

Ribeiro, Natalie Emanuelle, Pereira, Pedro Silvino, de Oliveira, Tatiane Bezerra, de Arruda Lima, Sandrine Maria, Silva, Tania Maria Sarmento, Santana, AndrÃ©a Lopes Bandeira Delmiro, do Nascimento, M

Journal:

Regulatory Toxicology and Pharmacology

Year:

2020

File:

PDF, 7.35 MB

2020

8

Safety evaluation of collagenase from Streptomyces violaceoruber

Harazono, Koichi, Atsumi, Yuta, Shirasaka, Naoki

Journal:

Regulatory Toxicology and Pharmacology

Year:

2020

File:

PDF, 400 KB

2020

9

Nonclinical safety assessment of repeated administration and biodistribution of a novel rabies self-amplifying mRNA vaccine in rats

Stokes, Alan, Pion, Johanne, Binazon, Ornella, Laffont, Benoit, Bigras, Maude, Dubois, Guillaume, Blouin, Karine, Young, Jamie K., Ringenberg, Michael A., Ben Abdeljelil, Nawel, Haruna, Julius, Rodrig

Journal:

Regulatory Toxicology and Pharmacology

Year:

2020

File:

PDF, 875 KB

2020

10

Risk assessment implications of site-specific oral relative bioavailability factors and dermal absorption fractions for polycyclic aromatic hydrocarbons in surface soils impacted by clay skeet target fragments

Haney, Joseph T., Forsberg, Norman D., Hoeger, Glenn C., Magee, Brian H., Meyer, Anita K.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2020

File:

PDF, 2.01 MB

2020

11

Cyto-genotoxic evaluation of novel anti-tubercular copper (II) complexes containing isoniazid-based ligands

Fregonezi, NathÃ¡lia Ferreira, Aparecida de Souza, Fabiana, Aleixo, Nadia Andrade, Stefany da Silva Gomes, Pietra, Silvestre, Rafaela Baldassari, De Grandis, Rone Aparecido, Bento da Silva, Patricia,

Journal:

Regulatory Toxicology and Pharmacology

Year:

2020

File:

PDF, 879 KB

2020

12

An analysis of the setting of the acute reference dose (ARfD) for pesticides in Europe

Moxon, Mary, Strupp, Christian, Aggarwal, Manoj, Odum, Jenny, Lewis, Richard, Zedet, StÃ©phanie, Mehta, Jyotigna

Journal:

Regulatory Toxicology and Pharmacology

Year:

2020

File:

PDF, 891 KB

2020

13

The limitations of using the NTP chronic bioassay on vanadium pentoxide in risk assessments

MacGregor, Judith A., White, David J., Williams, Amy Lavin

Journal:

Regulatory Toxicology and Pharmacology

Year:

2020

File:

PDF, 1.62 MB

2020

14

OECD 428 in vitro dermal absorption mass balance performance based on our in-house database of pesticide studies

Journal:

Regulatory Toxicology and Pharmacology

Year:

2020

File:

PDF, 674 KB

2020

15

Comparison of threshold of toxicological concern (TTC) values to oral reference dose (RfD) values

Pham, Ly L., Borghoff, Susan J., Thompson, Chad M.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2020

File:

PDF, 1.19 MB

2020

16

Cell proliferation analysis is a reliable predictor of lack of carcinogenicity: Case study using the pyrethroid imiprothrin on lung tumorigenesis in mice

Kawamoto, Kensuke, Ogata, Keiko, Asano, Hiroyuki, Miyata, Kaori, Sukata, Tokuo, Utsumi, Tooru, Cohen, Samuel M., Yamada, Tomoya

Journal:

Regulatory Toxicology and Pharmacology

Year:

2020

File:

PDF, 4.08 MB

2020

17

Editorial Board

Journal:

Regulatory Toxicology and Pharmacology

Year:

2020

File:

PDF, 28 KB

2020

18

Short-term toxicogenomics as an alternative approach to chronic in vivo studies for derivation of points of departure: A case study in the rat with a triazole fungicide

LaRocca, Jessica, Costa, Eduardo, Sriram, Shreedharan, Hannas, Bethany R., Johnson, Kamin J.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2020

File:

PDF, 1.74 MB

2020

19

Is there a rationale for direct dosing of chemicals to nursing pups in the EOGRTS (OECD 443)?

Arts, Josje, Beekhuijzen, Manon

Journal:

Regulatory Toxicology and Pharmacology

Year:

2020

File:

PDF, 165 KB

2020

20

Use of toxicokinetic data for afidopyropen to determine the dose levels in developmental toxicity studies

Loccisano, Anne E., Bus, James, Gollapudi, Bhaskar, Riffle, Brandy, Frericks, Markus, Fegert, Ivana, Fabian, Eric

Journal:

Regulatory Toxicology and Pharmacology

Year:

2020

File:

PDF, 790 KB

2020

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