Regulatory Toxicology and Pharmacology

1

Assessment of undesirable events in cosmetic market surveillance: Background, description and use of a causality assessment method in cosmetovigilance

B. Bons, F. Audebert, C. Bitaudeau, N. Cachin, L. Colson, C. Farr, L.A. Fix, N. Gilmour, R. Gorni, M. Griffiths, B. Harris, V. Holle, S. Kirk, E. Meredith, C. Pari, P. Poinsot, G. Renner

Journal:

Year:

2010

Language:

english

File:

PDF, 646 KB

english, 2010

2

The value of acute toxicity studies to support the clinical management of overdose and poisoning: A cross-discipline consensus

Kathryn Chapman, Stuart Creton, Hugo Kupferschmidt, G. Randall Bond, Martin F. Wilks, Sally Robinson

Journal:

Regulatory Toxicology and Pharmacology

Year:

2010

Language:

english

File:

PDF, 222 KB

english, 2010

3

The antipsychotics haloperidol and chlorpromazine increase bone metabolism and induce osteopenia in female rats

Takeshi Kunimatsu, Juki Kimura, Hitoshi Funabashi, Tadashi Inoue, Takaki Seki

Journal:

Regulatory Toxicology and Pharmacology

Year:

2010

Language:

english

File:

PDF, 1.27 MB

english, 2010

4

Toxicogenomics and cancer risk assessment: A framework for key event analysis and dose–response assessment for nongenotoxic carcinogens

Joel P. Bercu, Robert A. Jolly, Kelly M. Flagella, Thomas K. Baker, Pedro Romero, James L. Stevens

Journal:

Regulatory Toxicology and Pharmacology

Year:

2010

Language:

english

File:

PDF, 1021 KB

english, 2010

5

An enhanced tiered toxicity testing framework with triggers for assessing hazards and risks of commodity chemicals

Laura M. Plunkett, A. Michael Kaplan, Richard A. Becker

Journal:

Regulatory Toxicology and Pharmacology

Year:

2010

Language:

english

File:

PDF, 757 KB

english, 2010

6

Acute oral toxicity: Variability, reliability, relevance and interspecies comparison of rodent LD50 data from literature surveyed for the ACuteTox project

Sebastian Hoffmann, Agnieszka Kinsner-Ovaskainen, Pilar Prieto, Inge Mangelsdorf, Christian Bieler, Thomas Cole

Journal:

Regulatory Toxicology and Pharmacology

Year:

2010

Language:

english

File:

PDF, 887 KB

english, 2010

7

Exposure-based waiving under REACH

Theo Vermeire, Marja van de Bovenkamp, Yuri Bruinen de Bruin, Christiaan Delmaar, Jacqueline van Engelen, Sylvia Escher, Hans Marquart, Tim Meijster

Journal:

Regulatory Toxicology and Pharmacology

Year:

2010

Language:

english

File:

PDF, 682 KB

english, 2010

8

Acute and sub-chronic oral toxicological evaluations of quinocetone in Wistar rats

Xu Wang, Wei Zhang, Yulian Wang, Dapeng Peng, Awais Ihsan, Xianju Huang, Lingli Huang, Zhenli Liu, Menghong Dai, Wen Zhou, Zong-Hui Yuan

Journal:

Regulatory Toxicology and Pharmacology

Year:

2010

Language:

english

File:

PDF, 635 KB

english, 2010

9

Cytotoxicity of eight cigarette smoke condensates in three test systems: Comparisons between assays and condensates

Patricia A. Richter, Albert P. Li, Gregory Polzin, Shambhu K. Roy

Journal:

Regulatory Toxicology and Pharmacology

Year:

2010

Language:

english

File:

PDF, 345 KB

english, 2010

10

Risk assessment of thujone in foods and medicines containing sage and wormwood – Evidence for a need of regulatory changes?

Dirk W. Lachenmeier, Michael Uebelacker

Journal:

Regulatory Toxicology and Pharmacology

Year:

2010

Language:

english

File:

PDF, 285 KB

english, 2010

11

Respiratory safety pharmacology: Concurrent validation of volume, rate, time, flow and ratio variables in conscious male Sprague–Dawley rats

Margarita Legaspi, Simon Authier, Dominique Gauvin, Maxim Moreau, Guy Beauchamp, Fernando Chaurand, Eric Troncy

Journal:

Regulatory Toxicology and Pharmacology

Year:

2010

Language:

english

File:

PDF, 844 KB

english, 2010

12

Benchmark dose approaches in chemical health risk assessment in relation to number and distress of laboratory animals

Mattias Öberg

Journal:

Regulatory Toxicology and Pharmacology

Year:

2010

Language:

english

File:

PDF, 164 KB

english, 2010

13

Review of fullerene toxicity and exposure – Appraisal of a human health risk assessment, based on open literature

Karin Aschberger, Helinor J. Johnston, Vicki Stone, Robert J. Aitken, C. Lang Tran, Steven M. Hankin, Sheona A.K. Peters, Frans M. Christensen

Journal:

Regulatory Toxicology and Pharmacology

Year:

2010

Language:

english

File:

PDF, 357 KB

english, 2010

14

Safety assessment of Cry1C protein from genetically modified rice according to the national standards of PR China for a new food resource

Sishuo Cao, Xiaoyun He, Wentao Xu, Wenjun Ran, Lixing Liang, YunBo Luo, Yanfang Yuan, Nan Zhang, Xin Zhou, Kunlun Huang

Journal:

Regulatory Toxicology and Pharmacology

Year:

2010

Language:

english

File:

PDF, 319 KB

english, 2010

15

Integrating variability in half-lives and dietary intakes to predict mercury concentration in hair

Isabelle Albert, Grégory Villeret, Alain Paris, Philippe Verger

Journal:

Regulatory Toxicology and Pharmacology

Year:

2010

Language:

english

File:

PDF, 358 KB

english, 2010

16

Safety assessment of EPA-rich oil produced from yeast: Results of a 90-day subchronic toxicity study

Susan A. MacKenzie, Leigh A. Belcher, Greg P. Sykes, Steven R. Frame, Pushkor Mukerji, Peter J. Gillies

Journal:

Regulatory Toxicology and Pharmacology

Year:

2010

Language:

english

File:

PDF, 284 KB

english, 2010

17

Limitations in the characterisation of cigarette products using different machine smoking regimes

Stephen W. Purkis, Valerie Troude, Gerald Duputié, Christian Tessier

Journal:

Regulatory Toxicology and Pharmacology

Year:

2010

Language:

english

File:

PDF, 925 KB

english, 2010

18

Predicted critical environmental concentrations for 500 pharmaceuticals

Jerker Fick, Richard H. Lindberg, Mats Tysklind, D.G. Joakim Larsson

Journal:

Regulatory Toxicology and Pharmacology

Year:

2010

Language:

english

File:

PDF, 190 KB

english, 2010

19

Corrigendum to ‘A tiered approach to the use of alternatives to animal testing for the safety assessment of cosmetics: Genotoxicity. A COLIPA analysis’ [Regulatory Toxicology and Pharmacology 57 (2010) 315–324]

Stefan Pfuhler, Annette Kirst, Marilyn Aardema, Norbert Banduhn, Carsten Goebel, Daisuke Araki, Margit Costabel-Farkas, Eric Dufour, Rolf Fautz, James Harvey, Nicola J. Hewitt, Jalila Hibatallah, Paul

Journal:

Regulatory Toxicology and Pharmacology

Year:

2010

Language:

english

File:

PDF, 127 KB

english, 2010

20

A cross-sectional analysis of reported corporate environmental sustainability practices

Dallas M. Cowan, Pamela Dopart, Tyler Ferracini, Jennifer Sahmel, Kimberly Merryman, Shannon Gaffney, Dennis J. Paustenbach

Journal:

Regulatory Toxicology and Pharmacology

Year:

2010

Language:

english

File:

PDF, 1.19 MB

english, 2010

21

The evaluation of drug rechallenge: The casopitant Phase III program

Christine M. Hunt, Julie I. Papay, Donna S. Rich, Christopher J. Abissi, Mark W. Russo

Journal:

Regulatory Toxicology and Pharmacology

Year:

2010

Language:

english

File:

PDF, 223 KB

english, 2010

22

Cover 2–Editorial Board

Journal:

Regulatory Toxicology and Pharmacology

Year:

2010

Language:

english

File:

PDF, 35 KB

english, 2010

23

Volume 58; Issue 3

Regulatory Toxicology and Pharmacology

Assessment of undesirable events in cosmetic market surveillance: Background, description and use of a causality assessment method in cosmetovigilance

The value of acute toxicity studies to support the clinical management of overdose and poisoning: A cross-discipline consensus

The antipsychotics haloperidol and chlorpromazine increase bone metabolism and induce osteopenia in female rats

Toxicogenomics and cancer risk assessment: A framework for key event analysis and dose–response assessment for nongenotoxic carcinogens

An enhanced tiered toxicity testing framework with triggers for assessing hazards and risks of commodity chemicals

Acute oral toxicity: Variability, reliability, relevance and interspecies comparison of rodent LD50 data from literature surveyed for the ACuteTox project

Exposure-based waiving under REACH

Acute and sub-chronic oral toxicological evaluations of quinocetone in Wistar rats

Cytotoxicity of eight cigarette smoke condensates in three test systems: Comparisons between assays and condensates

Risk assessment of thujone in foods and medicines containing sage and wormwood – Evidence for a need of regulatory changes?

Respiratory safety pharmacology: Concurrent validation of volume, rate, time, flow and ratio variables in conscious male Sprague–Dawley rats

Benchmark dose approaches in chemical health risk assessment in relation to number and distress of laboratory animals

Review of fullerene toxicity and exposure – Appraisal of a human health risk assessment, based on open literature

Safety assessment of Cry1C protein from genetically modified rice according to the national standards of PR China for a new food resource

Integrating variability in half-lives and dietary intakes to predict mercury concentration in hair

Safety assessment of EPA-rich oil produced from yeast: Results of a 90-day subchronic toxicity study

Limitations in the characterisation of cigarette products using different machine smoking regimes

Predicted critical environmental concentrations for 500 pharmaceuticals

Corrigendum to ‘A tiered approach to the use of alternatives to animal testing for the safety assessment of cosmetics: Genotoxicity. A COLIPA analysis’ [Regulatory Toxicology and Pharmacology 57 (2010) 315–324]

A cross-sectional analysis of reported corporate environmental sustainability practices

The evaluation of drug rechallenge: The casopitant Phase III program

Cover 2–Editorial Board

Table of Contents