Regulatory Toxicology and Pharmacology

1

Further investigations into the genotoxicity of 2,6-xylidine and one of its key metabolites

David Kirkland, Mark Ballantyne, Stefanie Harlfinger, Olaf Will, Ulrich Jahnel, Alexander Kraus, Corinne van Dorp

Journal:

Year:

2012

Language:

english

File:

PDF, 370 KB

english, 2012

2

Correlation of chemical structure with reproductive and developmental toxicity as it relates to the use of the threshold of toxicological concern

Michael C. Laufersweiler, Bernard Gadagbui, Irene M. Baskerville-Abraham, Andrew Maier, Alison Willis, Anthony R. Scialli, Gregory J. Carr, Susan P. Felter, Karen Blackburn, George Daston

Journal:

Regulatory Toxicology and Pharmacology

Year:

2012

Language:

english

File:

PDF, 880 KB

english, 2012

3

Safety evaluation of Mucor rouxii CFR-G15 biomass containing ω-6 fatty acids in rats

S.S. Mamatha, S.P. Muthukumar, G. Venkateswaran

Journal:

Regulatory Toxicology and Pharmacology

Year:

2012

Language:

english

File:

PDF, 328 KB

english, 2012

4

Development of a unit risk factor for nickel and inorganic nickel compounds based on an updated carcinogenic toxicity assessment

Joseph T. Haney Jr., Darrell D. McCant, Robert L. Sielken Jr., Ciriaco Valdez-Flores, Roberta L. Grant

Journal:

Regulatory Toxicology and Pharmacology

Year:

2012

Language:

english

File:

PDF, 401 KB

english, 2012

5

A review of current smoke constituent measurement activities and aspects of yield variability

Stephen W. Purkis, Michael Meger, Roland Wuttke

Journal:

Regulatory Toxicology and Pharmacology

Year:

2012

Language:

english

File:

PDF, 1006 KB

english, 2012

6

CYP2F2-generated metabolites, not styrene oxide, are a key event mediating the mode of action of styrene-induced mouse lung tumors

G. Cruzan, J. Bus, J. Hotchkiss, J. Harkema, M. Banton, S. Sarang

Journal:

Regulatory Toxicology and Pharmacology

Year:

2012

Language:

english

File:

PDF, 970 KB

english, 2012

7

Design and chemical evaluation of reduced machine-yield cigarettes

K.G. McAdam, E.O. Gregg, M. Bevan, D.J. Dittrich, S. Hemsley, C. Liu, C.J. Proctor

Journal:

Regulatory Toxicology and Pharmacology

Year:

2012

Language:

english

File:

PDF, 337 KB

english, 2012

8

Chitosan induced hepato-nephrotoxicity in mice with special reference to gender effect in glycolytic enzymes activities

Enayat A. Omara, Hanan F. Aly, Somaia A. Nada

Journal:

Regulatory Toxicology and Pharmacology

Year:

2012

Language:

english

File:

PDF, 4.22 MB

english, 2012

9

Assessment of the health risks related to the presence of drug residues in water for human consumption: Application to carbamazepine

Paul Houeto, Aude Carton, Michel Guerbet, Anne-Cécile Mauclaire, Chantal Gatignol, Philippe Lechat, Dominique Masset

Journal:

Regulatory Toxicology and Pharmacology

Year:

2012

Language:

english

File:

PDF, 345 KB

english, 2012

10

In vitro enrofloxacin binding in human fecal slurries

Youngbeom Ahn, Sean W. Linder, Brian T. Veach, S. Steve Yan, A. Haydée Fernández, Silvia A. Pineiro, Carl E. Cerniglia

Journal:

Regulatory Toxicology and Pharmacology

Year:

2012

Language:

english

File:

PDF, 432 KB

english, 2012

11

A consistent and transparent approach for calculation of Derived No-Effect Levels (DNELs) for petroleum substances

Peter J. Boogaard, Marcy I. Banton, Walden Dalbey, Anna S. Hedelin, Anthony J. Riley, Erik K. Rushton, Mathieu Vaissière, Gary D. Minsavage

Journal:

Regulatory Toxicology and Pharmacology

Year:

2012

Language:

english

File:

PDF, 285 KB

english, 2012

12

Discriminatory power of standard toxicity assays used to evaluate ingredients added to cigarettes

Michael J. Oldham, Hans-Juergen Haussmann, Willy Gomm, Lonnie T. Rimmer, Michael J. Morton, Willie J. McKinney Jr.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.14 MB

english, 2012

13

Predicting blood:air partition coefficients using basic physicochemical properties

Harrie E. Buist, Lianne de Wit-Bos, Tialda Bouwman, Wouter H.J. Vaes

Journal:

Regulatory Toxicology and Pharmacology

Year:

2012

Language:

english

File:

PDF, 503 KB

english, 2012

14

Biomonitoring Equivalents for benzene

Sean M. Hays, David W. Pyatt, Chris R. Kirman, Lesa L. Aylward

Journal:

Regulatory Toxicology and Pharmacology

Year:

2012

Language:

english

File:

PDF, 625 KB

english, 2012

15

In vivo genotoxicity study of titanium dioxide nanoparticles using comet assay following intratracheal instillation in rats

Masato Naya, Norihiro Kobayashi, Makoto Ema, Sawako Kasamoto, Masahito Fukumuro, Shigeaki Takami, Madoka Nakajima, Makoto Hayashi, Junko Nakanishi

Journal:

Regulatory Toxicology and Pharmacology

Year:

2012

Language:

english

File:

PDF, 917 KB

english, 2012

16

Subacute toxicity assessment of carotenoids extracted from citrus peel (Nanfengmiju, Citrus reticulata Blanco) in rats

Feng Xue, Chen Li, Siyi Pan

Journal:

Regulatory Toxicology and Pharmacology

Year:

2012

Language:

english

File:

PDF, 183 KB

english, 2012

17

Naphthalene animal carcinogenicity and human relevancy: Overview of industries with naphthalene-containing streams

R. Jeffrey Lewis

Journal:

Regulatory Toxicology and Pharmacology

Year:

2012

Language:

english

File:

PDF, 203 KB

english, 2012

18

A refined approach to estimate exposure for use in calculating the Maximum Residue Limit of veterinary drugs

Dugald J. MacLachlan, Utz Mueller

Journal:

Regulatory Toxicology and Pharmacology

Year:

2012

Language:

english

File:

PDF, 211 KB

english, 2012

19

Assessing the non-cancer risk for RDX (hexahydro-1,3,5-trinitro-1,3,5-triazine) using physiologically based pharmacokinetic (PBPK) modeling

Lisa M. Sweeney, Chester P. Gut Jr., Michael L. Gargas, Gunda Reddy, Larry R. Williams, Mark S. Johnson

Journal:

Regulatory Toxicology and Pharmacology

Year:

2012

Language:

english

File:

PDF, 385 KB

english, 2012

20

Development of safety profile evaluating pharmacokinetics, pharmacodynamics and toxicity of a combination of pioglitazone and olmesartan medoxomil in Wistar albino rats

Pinaki Sengupta, Utpal Nandi, Tapan Kumar Pal

Journal:

Regulatory Toxicology and Pharmacology

Year:

2012

Language:

english

File:

PDF, 918 KB

english, 2012

21

Risk assessment of chlorpyrifos on rice and cabbage in China

Chen Chen, Yongzhong Qian, Xianjin Liu, Chuanjiang Tao, Ying Liang, Yun Li

Journal:

Regulatory Toxicology and Pharmacology

Year:

2012

Language:

english

File:

PDF, 185 KB

english, 2012

22

A nonclinical safety and pharmacokinetic evaluation of N6022: A first-in-class S-nitrosoglutathione reductase inhibitor for the treatment of asthma

Dorothy B. Colagiovanni, Daniel W. Drolet, Emilie Langlois-Forget, Marie-Pier Piché, Doug Looker, Gary J. Rosenthal

Journal:

Regulatory Toxicology and Pharmacology

Year:

2012

Language:

english

File:

PDF, 680 KB

english, 2012

23

Cover 2–Editorial Board

Journal:

Regulatory Toxicology and Pharmacology

Year:

2012

Language:

english

File:

PDF, 36 KB

english, 2012

24

Volume 62; Issue 1

Regulatory Toxicology and Pharmacology

Further investigations into the genotoxicity of 2,6-xylidine and one of its key metabolites

Correlation of chemical structure with reproductive and developmental toxicity as it relates to the use of the threshold of toxicological concern

Safety evaluation of Mucor rouxii CFR-G15 biomass containing ω-6 fatty acids in rats

Development of a unit risk factor for nickel and inorganic nickel compounds based on an updated carcinogenic toxicity assessment

A review of current smoke constituent measurement activities and aspects of yield variability

CYP2F2-generated metabolites, not styrene oxide, are a key event mediating the mode of action of styrene-induced mouse lung tumors

Design and chemical evaluation of reduced machine-yield cigarettes

Chitosan induced hepato-nephrotoxicity in mice with special reference to gender effect in glycolytic enzymes activities

Assessment of the health risks related to the presence of drug residues in water for human consumption: Application to carbamazepine

In vitro enrofloxacin binding in human fecal slurries

A consistent and transparent approach for calculation of Derived No-Effect Levels (DNELs) for petroleum substances

Discriminatory power of standard toxicity assays used to evaluate ingredients added to cigarettes

Predicting blood:air partition coefficients using basic physicochemical properties

Biomonitoring Equivalents for benzene

In vivo genotoxicity study of titanium dioxide nanoparticles using comet assay following intratracheal instillation in rats

Subacute toxicity assessment of carotenoids extracted from citrus peel (Nanfengmiju, Citrus reticulata Blanco) in rats

Naphthalene animal carcinogenicity and human relevancy: Overview of industries with naphthalene-containing streams

A refined approach to estimate exposure for use in calculating the Maximum Residue Limit of veterinary drugs

Assessing the non-cancer risk for RDX (hexahydro-1,3,5-trinitro-1,3,5-triazine) using physiologically based pharmacokinetic (PBPK) modeling

Development of safety profile evaluating pharmacokinetics, pharmacodynamics and toxicity of a combination of pioglitazone and olmesartan medoxomil in Wistar albino rats

Risk assessment of chlorpyrifos on rice and cabbage in China

A nonclinical safety and pharmacokinetic evaluation of N6022: A first-in-class S-nitrosoglutathione reductase inhibitor for the treatment of asthma

Cover 2–Editorial Board

Table of Contents