Regulatory Toxicology and Pharmacology

1

Evaluation of vinyl laurate in a battery of in vitro and in vivo tests for genotoxicity

van Acker, Frédérique, Messinger, Horst, Bär, Albert

Journal:

Year:

2015

Language:

english

File:

PDF, 687 KB

english, 2015

2

Human urine and plasma concentrations of bisphenol A extrapolated from pharmacokinetics established in in vivo experiments with chimeric mice with humanized liver and semi-physiological pharmacokinetic modeling

Miyaguchi, Takamori, Suemizu, Hiroshi, Shimizu, Makiko, Shida, Satomi, Nishiyama, Sayako, Takano, Ryohji, Murayama, Norie, Yamazaki, Hiroshi

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 814 KB

english, 2015

3

A feasibility study: Can information collected to classify for mutagenicity be informative in predicting carcinogenicity?

Petkov, Petko I., Patlewicz, Grace, Schultz, Terry W., Honma, Masamitsu, Todorov, Milen, Kotov, Stefan, Dimitrov, Sabcho D., Donner, E. Maria, Mekenyan, Ovanes G.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.18 MB

english, 2015

4

Safety evaluation of the human-identical milk monosaccharide, l-fucose

Choi, Sharon S.H., Lynch, Barry S., Baldwin, Nigel, Dakoulas, Emily W., Roy, Shambhu, Moore, Carey, Thorsrud, Bjorn A., Röhrig, Christoph H.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 509 KB

english, 2015

5

Opinion on environmental risks and indirect health effects of mercury from dental amalgam

Scientific Committee SCHER,, Linders, Jan, Janssen, Colin, Testai, Emanuela, Vighi, Marco, Dekant, Wolfgang, Munth, John, Pirrone, Nicola, Richardson, Mark

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 210 KB

english, 2015

6

MRL calculations based on both intra- and inter-trial residue variability

Hamilton, Denis J.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 647 KB

english, 2015

7

Biomonitoring Equivalents for interpretation of urinary fluoride

Aylward, L.L., Hays, S.M., Vezina, A., Deveau, M., St-Amand, A., Nong, A.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.29 MB

english, 2015

8

An improved method for the isolation of rat alveolar type II lung cells: Use in the Comet assay to determine DNA damage induced by cigarette smoke

Dalrymple, Annette, Ordoñez, Patricia, Thorne, David, Dillon, Debbie, Meredith, Clive

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 741 KB

english, 2015

9

Are the elements of the proposed ozone National Ambient Air Quality Standards informed by the best available science?

Goodman, Julie E., Sax, Sonja N., Lange, Sabine, Rhomberg, Lorenz R.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 395 KB

english, 2015

10

Pre-clinical toxicity evaluation of MB-102, a novel fluorescent tracer agent for real-time measurement of glomerular filtration rate

Bugaj, Joseph E., Dorshow, Richard B.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 841 KB

english, 2015

11

Relevance of the mouse skin initiation–promotion model for the classification of carcinogenic substances encountered at the workplace

Schwarz, Michael, Thielmann, Heinz W., Meischner, Veronika, Fartasch, Manigé

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 356 KB

english, 2015

12

Building scientific confidence in the development and evaluation of read-across

Patlewicz, G., Ball, N., Boogaard, P.J., Becker, R.A., Hubesch, B.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 2.48 MB

english, 2015

13

Evaluation of the ToxRTool’s ability to rate the reliability of toxicological data for human health hazard assessments

Segal, D., Makris, S.L., Kraft, A.D., Bale, A.S., Fox, J., Gilbert, M., Bergfelt, D.R., Raffaele, K.C., Blain, R.B., Fedak, K.M., Selgrade, M.K., Crofton, K.M.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 701 KB

english, 2015

14

Assessment of an extended dataset of in vitro human dermal absorption studies on pesticides to determine default values, opportunities for read-across and influence of dilution on absorption

Aggarwal, M., Fisher, P., Hüser, A., Kluxen, F.M., Parr-Dobrzanski, R., Soufi, M., Strupp, C., Wiemann, C., Billington, R.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.52 MB

english, 2015

15

Genomics in the land of regulatory science

Tong, Weida, Ostroff, Stephen, Blais, Burton, Silva, Primal, Dubuc, Martine, Healy, Marion, Slikker, William

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 409 KB

english, 2015

16

Is the shape of the decline in risk following quitting smoking similar for squamous cell carcinoma and adenocarcinoma of the lung? A quantitative review using the negative exponential model

Fry, John S., Lee, Peter N., Forey, Barbara A., Coombs, Katharine J.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 345 KB

english, 2015

18

Cover 2–Editorial Board

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 34 KB

english, 2015

19

A longitudinal study of smokers’ exposure to cigarette smoke and the effects of spontaneous product switching

Cunningham, Anthony, Sommarström, Johan, Camacho, Oscar M., Sisodiya, Ajit S., Prasad, Krishna

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 584 KB

english, 2015

20

Providing perspective for interpreting cardiovascular mortality risks associated with ozone exposures

Petito Boyce, Catherine, Goodman, Julie E., Sax, Sonja N., Loftus, Christine T.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 869 KB

english, 2015

21

A novel approach to assess the population health impact of introducing a Modified Risk Tobacco Product

Weitkunat, Rolf, Lee, Peter N., Baker, Gizelle, Sponsiello-Wang, Zheng, González-Zuloeta Ladd, Angela M., Lüdicke, Frank

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 435 KB

english, 2015

Volume 72; Issue 1

Regulatory Toxicology and Pharmacology

Evaluation of vinyl laurate in a battery of in vitro and in vivo tests for genotoxicity

Human urine and plasma concentrations of bisphenol A extrapolated from pharmacokinetics established in in vivo experiments with chimeric mice with humanized liver and semi-physiological pharmacokinetic modeling

A feasibility study: Can information collected to classify for mutagenicity be informative in predicting carcinogenicity?

Safety evaluation of the human-identical milk monosaccharide, l-fucose

Opinion on environmental risks and indirect health effects of mercury from dental amalgam

MRL calculations based on both intra- and inter-trial residue variability

Biomonitoring Equivalents for interpretation of urinary fluoride

An improved method for the isolation of rat alveolar type II lung cells: Use in the Comet assay to determine DNA damage induced by cigarette smoke

Are the elements of the proposed ozone National Ambient Air Quality Standards informed by the best available science?

Pre-clinical toxicity evaluation of MB-102, a novel fluorescent tracer agent for real-time measurement of glomerular filtration rate

Relevance of the mouse skin initiation–promotion model for the classification of carcinogenic substances encountered at the workplace

Building scientific confidence in the development and evaluation of read-across

Evaluation of the ToxRTool’s ability to rate the reliability of toxicological data for human health hazard assessments

Assessment of an extended dataset of in vitro human dermal absorption studies on pesticides to determine default values, opportunities for read-across and influence of dilution on absorption

Genomics in the land of regulatory science

Table of Contents

Is the shape of the decline in risk following quitting smoking similar for squamous cell carcinoma and adenocarcinoma of the lung? A quantitative review using the negative exponential model

Cover 2–Editorial Board

A longitudinal study of smokers’ exposure to cigarette smoke and the effects of spontaneous product switching

Providing perspective for interpreting cardiovascular mortality risks associated with ozone exposures

A novel approach to assess the population health impact of introducing a Modified Risk Tobacco Product