Regulatory Toxicology and Pharmacology

1

Carcinogenicity assessment of the pan-caspase inhibitor, emricasan, in Tg.rasH2 mice

Elbekai, R.H., Paranjpe, M.G., Contreras, P.C., Spada, A.

Journal:

Year:

2015

Language:

english

File:

PDF, 442 KB

english, 2015

2

Safety and compliance of a complex homeopathic drug (Contramutan N Saft) in the treatment of acute respiratory tract infections: A large observational (non-interventional) study in children and adults focussing on homeopathy specific adverse reactions versus adverse drug reactions

Michalsen, Andreas, Uehleke, Bernhard, Stange, Rainer

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 395 KB

english, 2015

3

Comparative endpoint sensitivity of in vitro estrogen agonist assays

Dreier, David A., Connors, Kristin A., Brooks, Bryan W.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 457 KB

english, 2015

4

Pronamide: Weight of evidence for potential estrogen, androgen or thyroid effects

Marty, Mary Sue, Papineni, Sabitha, Coady, Katherine K., Rasoulpour, Reza J., Pottenger, Lynn H., Eisenbrandt, David L.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 633 KB

english, 2015

5

Toxicological risk assessment of elemental gold following oral exposure to sheets and nanoparticles – A review

Hadrup, Niels, Sharma, Anoop K., Poulsen, Morten, Nielsen, Elsa

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 557 KB

english, 2015

6

Method for the determination of ammonium in cigarette tobacco using ion chromatography

Watson, Christina Vaughan, Valentin-Blasini, Liza, Damian, Maria, Watson, Clifford H.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 847 KB

english, 2015

7

Development of a risk management tool for prioritizing chemical hazard-food pairs and demonstration for selected mycotoxins

Stornetta, Alessia, Engeli, Barbara E., Zarn, Jürg A., Gremaud, Gérard, Sturla, Shana J.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.49 MB

english, 2015

8

A strategy for safety assessment of chemicals with data gaps for developmental and/or reproductive toxicity

Blackburn, Karen, Daston, George, Fisher, Joan, Lester, Cathy, Naciff, Jorge M., Rufer, Echoleah S., Stuard, Sharon B., Woeller, Kara

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.20 MB

english, 2015

9

Allergenicity characteristics of germinated soybean proteins in a BALB/c mouse model

Yang, Hui, Gao, Jinyan, Yang, Anshu, Lu, Jun, Chen, Hongbing

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.76 MB

english, 2015

10

Pronamide: Human relevance of liver-mediated rat leydig cell tumors

Rasoulpour, Reza J., Andrus, Amanda K., Marty, M. Sue, Zhang, Fagen, Thomas, Johnson, LeBaron, Matthew J., Papineni, Sabitha, Pottenger, Lynn H., Eisenbrandt, David L.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.06 MB

english, 2015

11

Acute and repeated doses (28 days) oral toxicity study of glycosides based standardized fenugreek seed extract in laboratory mice

Kandhare, Amit D., Bodhankar, Subhash L., Mohan, V., Thakurdesai, Prasad A.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 5.53 MB

english, 2015

12

Improving the power of long term rodent carcinogenicity bioassays by adjusting the experimental design

Jackson, Matthew T.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 630 KB

english, 2015

13

Nanoparticles skin absorption: New aspects for a safety profile evaluation

Larese Filon, Francesca, Mauro, Marcella, Adami, Gianpiero, Bovenzi, Massimo, Crosera, Matteo

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.27 MB

english, 2015

14

Technical guide for applications of gene expression profiling in human health risk assessment of environmental chemicals

Bourdon-Lacombe, Julie A., Moffat, Ivy D., Deveau, Michelle, Husain, Mainul, Auerbach, Scott, Krewski, Daniel, Thomas, Russell S., Bushel, Pierre R., Williams, Andrew, Yauk, Carole L.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 955 KB

english, 2015

15

A practical application of two in silico systems for identification of potentially mutagenic impurities

Greene, Nigel, Dobo, Krista L., Kenyon, Michelle O., Cheung, Jennifer, Munzner, Jennifer, Sobol, Zhanna, Sluggett, Gregory, Zelesky, Todd, Sutter, Andreas, Wichard, Joerg

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 2.08 MB

english, 2015

16

Hepatotoxicity induced by acute and chronic paracetamol overdose in adults. Where do we stand?

Tong, Hoi Y., Medrano, Nicolás, Borobia, Alberto M., Martínez, Ana M., Martín, Julia, Ruiz, José A., García, Santos, Quintana, Manuel, Carcas, Antonio J., Frías, Jesús, Ramírez, Elena

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 889 KB

english, 2015

17

Rethinking guideline toxicity testing

Saghir, Shakil Ahmed

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 990 KB

english, 2015

18

An approach to ingredient screening and toxicological risk assessment of flavours in e-liquids

Costigan, S., Meredith, C.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 566 KB

english, 2015

19

Implications of dose-dependent target tissue absorption for linear and non-linear/threshold approaches in development of a cancer-based oral toxicity factor for hexavalent chromium

Haney, J.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.05 MB

english, 2015

20

Changes in levels of biomarkers of exposure and biological effect in a controlled study of smokers switched from conventional cigarettes to reduced-toxicant-prototype cigarettes

Shepperd, Christopher J., Newland, Nik, Eldridge, Alison, Haswell, Linsey, Lowe, Frazer, Papadopoulou, Ermioni, Camacho, Oscar, Proctor, Christopher J., Graff, Don, Meyer, Ingo

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 2.14 MB

english, 2015

21

Consumer exposure modelling under REACH: Assessing the defaults

Oltmanns, J., Neisel, F., Heinemeyer, G., Kaiser, E., Schneider, K.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 813 KB

english, 2015

22

Evaluation of subchronic (13week) toxicity and genotoxicity potential of vinegar-processed Genkwa Flos

Yun, Jun-Won, Kim, Seung-Hyun, Kim, Yun-Soon, You, Ji-Ran, Kwon, Euna, Jang, Ja-June, Park, In Ae, Kim, Hee Chan, Kim, Hyeon Hoe, Che, Jeong-Hwan, Kang, Byeong-Cheol

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 498 KB

english, 2015

23

Cover 2–Editorial Board

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 33 KB

english, 2015

24

Corrigendum to “Use of dose-dependent absorption into target tissues to more accurately predict cancer risk at low oral doses of hexavalent chromium” [Regul. Toxicol. Pharmacol. 71 (1) (2015) 93–100]

Haney, J.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 194 KB

english, 2015

26

Developmental immunotoxicity testing of 4-methyl anisole

Tonk, Elisa C.M., Verhoef, Aart, Gremmer, Eric R., van Loveren, Henk, Piersma, Aldert H.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.24 MB

english, 2015

27

Corrigendum to “Assessment of three approaches for regulatory decision making on pesticides with endocrine disrupting properties” [Regul. Toxicol. Pharmacol. 70 (3) (2014) 590–604]

Marx-Stoelting, P., Niemann, L., Ritz, V., Ulbrich, B., Gall, A., Hirsch-Ernst, K.I., Pfeil, R., Solecki, R.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 188 KB

english, 2015

28

Regulatory action and moderate decrease in methylphenidate use among ADHD diagnosed patients aged five and under in Korea

Shin, Ju-Young, Lee, Shin Haeng, Shin, Sun Mi, Shin, Han Na, Park, Byung-Joo

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 437 KB

english, 2015

29

Application of the KeratinoSens™ assay for assessing the skin sensitization potential of agrochemical active ingredients and formulations

Settivari, Raja S., Gehen, Sean C., Amado, Ricardo Acosta, Visconti, Nicolo R., Boverhof, Darrell R., Carney, Edward W.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 953 KB

english, 2015

Volume 72; Issue 2

Regulatory Toxicology and Pharmacology

Carcinogenicity assessment of the pan-caspase inhibitor, emricasan, in Tg.rasH2 mice

Safety and compliance of a complex homeopathic drug (Contramutan N Saft) in the treatment of acute respiratory tract infections: A large observational (non-interventional) study in children and adults focussing on homeopathy specific adverse reactions versus adverse drug reactions

Comparative endpoint sensitivity of in vitro estrogen agonist assays

Pronamide: Weight of evidence for potential estrogen, androgen or thyroid effects

Toxicological risk assessment of elemental gold following oral exposure to sheets and nanoparticles – A review

Method for the determination of ammonium in cigarette tobacco using ion chromatography

Development of a risk management tool for prioritizing chemical hazard-food pairs and demonstration for selected mycotoxins

A strategy for safety assessment of chemicals with data gaps for developmental and/or reproductive toxicity

Allergenicity characteristics of germinated soybean proteins in a BALB/c mouse model

Pronamide: Human relevance of liver-mediated rat leydig cell tumors

Acute and repeated doses (28 days) oral toxicity study of glycosides based standardized fenugreek seed extract in laboratory mice

Improving the power of long term rodent carcinogenicity bioassays by adjusting the experimental design

Nanoparticles skin absorption: New aspects for a safety profile evaluation

Technical guide for applications of gene expression profiling in human health risk assessment of environmental chemicals

A practical application of two in silico systems for identification of potentially mutagenic impurities

Hepatotoxicity induced by acute and chronic paracetamol overdose in adults. Where do we stand?

Rethinking guideline toxicity testing

An approach to ingredient screening and toxicological risk assessment of flavours in e-liquids

Implications of dose-dependent target tissue absorption for linear and non-linear/threshold approaches in development of a cancer-based oral toxicity factor for hexavalent chromium

Changes in levels of biomarkers of exposure and biological effect in a controlled study of smokers switched from conventional cigarettes to reduced-toxicant-prototype cigarettes

Consumer exposure modelling under REACH: Assessing the defaults

Evaluation of subchronic (13week) toxicity and genotoxicity potential of vinegar-processed Genkwa Flos

Cover 2–Editorial Board

Table of Contents

Corrigendum to “Use of dose-dependent absorption into target tissues to more accurately predict cancer risk at low oral doses of hexavalent chromium” [Regul. Toxicol. Pharmacol. 71 (1) (2015) 93–100]

Developmental immunotoxicity testing of 4-methyl anisole

Corrigendum to “Assessment of three approaches for regulatory decision making on pesticides with endocrine disrupting properties” [Regul. Toxicol. Pharmacol. 70 (3) (2014) 590–604]

Regulatory action and moderate decrease in methylphenidate use among ADHD diagnosed patients aged five and under in Korea

Application of the KeratinoSens™ assay for assessing the skin sensitization potential of agrochemical active ingredients and formulations