Regulatory Toxicology and Pharmacology

1

Principles for identification of High Potency Category Chemicals for which the Dermal Sensitisation Threshold (DST) approach should not be applied

Roberts, David W., Api, Anne Marie, Safford, Robert J., Lalko, Jon F.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.06 MB

english, 2015

2

Extension of the Dermal Sensitisation Threshold (DST) approach to incorporate chemicals classified as reactive

Safford, Robert J., Api, Anne Marie, Roberts, David W., Lalko, Jon F.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 966 KB

english, 2015

3

Modernizing problem formulation for risk assessment necessitates articulation of mode of action

Borgert, Christopher J., Wise, Kimberly, Becker, Richard A.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.77 MB

english, 2015

4

Comedications alter drug-induced liver injury reporting frequency: Data mining in the WHO VigiBase™

Suzuki, Ayako, Yuen, Nancy A., Ilic, Katarina, Miller, Richard T., Reese, Melinda J., Brown, H. Roger, Ambroso, Jeffrey I., Falls, J. Gregory, Hunt, Christine M.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.50 MB

english, 2015

5

Novel database for exposure to fragrance ingredients in cosmetics and personal care products

Comiskey, D., Api, A.M., Barratt, C., Daly, E.J., Ellis, G., McNamara, C., O’Mahony, C., Robison, S.H., Safford, B., Smith, B., Tozer, S.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.74 MB

english, 2015

6

Increasing Scientific Confidence in Adverse Outcome Pathways: Application of Tailored Bradford-Hill Considerations for Evaluating Weight of Evidence

Becker, Richard A., Ankley, Gerald T., Edwards, Stephen W., Kennedy, Sean W., Linkov, Igor, Meek, Bette, Sachana, Magdalini, Segner, Helmut, Van Der Burg, Bart, Villeneuve, Daniel L., Watanabe, Haruna

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 3.44 MB

english, 2015

7

Evaluation of Human Exposure to metals from some popular brands of underarm cosmetics in Nigeria

Iwegbue, Chukwujindu M.A.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 701 KB

english, 2015

8

Safety evaluation of Angelica gigas: Genotoxicity and 13-weeks oral subchronic toxicity in rats

Yun, Jun-Won, Che, Jeong-Hwan, Kwon, Euna, Kim, Yun-Soon, Kim, Seung-Hyun, You, Ji-Ran, Kim, Woo Ho, Kim, Hyeon Hoe, Kang, Byeong-Cheol

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 790 KB

english, 2015

9

Clinical and anatomic pathology effects of serial blood sampling in rat toxicology studies, using conventional or microsampling methods

Caron, Alexis, Lelong, Christine, Bartels, T., Dorchies, O., Gury, T., Chalier, Catherine, Benning, Véronique

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.67 MB

english, 2015

10

Developmental toxicity assessment of the new turf herbicide, methiozolin ([5-(2,6-difluorobenzyl)oxymethyl-5-methyl-3,3(3-methylthiophen-2-yl)-1,2-isoxazoline]), in rabbits

Lee, Jinsoo, Song, Jeongah, Jeong, Eun Ju, Chung, Moon-Koo, Hwang, Ki-Hwan, Koo, Suk-Jin, Yu, Wook-Joon

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 799 KB

english, 2015

11

Classification of dermal sensitizers in pharmaceutical manufacturing

Winkler, Gian C., Perino, Christopher, Araya, Selene H., Bechter, Rudolf, Kuster, Martin, Lovsin Barle, Ester

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 285 KB

english, 2015

12

Mutagenicity and chemopreventive activities of Astronium species assessed by Ames test

Resende, Flávia Aparecida, Campos, Debora Leite, da Silva, Viviane Cândida, De Grandis, Rone Aparecido, Souza, Leonardo Perez, Leonardo Junior, Carlos Sérgio, da Rocha, Cláudia Quintino, dos Santos, L

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 384 KB

english, 2015

13

A strategy for structuring and reporting a read-across prediction of toxicity

Schultz, T.W., Amcoff, P., Berggren, E., Gautier, F., Klaric, M., Knight, D.J., Mahony, C., Schwarz, M., White, A., Cronin, M.T.D.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.02 MB

english, 2015

14

Non-animal photosafety screening for complex cosmetic ingredients with photochemical and photobiochemical assessment tools

Nishida, Hayato, Hirota, Morihiko, Seto, Yoshiki, Suzuki, Gen, Kato, Masashi, Kitagaki, Masato, Sugiyama, Mariko, Kouzuki, Hirokazu, Onoue, Satomi

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.23 MB

english, 2015

15

In vitro metabolism of rebaudioside E under anaerobic conditions: Comparison with rebaudioside A

Purkayastha, Sidd, Bhusari, Sachin, Pugh, George, Teng, Xiaowei, Kwok, David, Tarka, Stanley M.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.10 MB

english, 2015

16

Bioaccessibility of micron-sized powder particles of molybdenum metal, iron metal, molybdenum oxides and ferromolybdenum – Importance of surface oxides

Mörsdorf, Alexander, Odnevall Wallinder, Inger, Hedberg, Yolanda

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.40 MB

english, 2015

17

Novel analytical method to measure formaldehyde release from heated hair straightening cosmetic products: Impact on risk assessment

Galli, Corrado Lodovico, Bettin, Federico, Metra, Pierre, Fidente, Paola, De Dominicis, Emiliano, Marinovich, Marina

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 627 KB

english, 2015

18

Threshold of toxicological concern (TTC) for developmental and reproductive toxicity of anticancer compounds

Stanard, Brad, Dolan, David G., Hanneman, William, Legare, Marie, Bercu, Joel P.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.05 MB

english, 2015

19

Sameness: The regulatory crux with nanomaterial identity and grouping schemes for hazard assessment

Walser, Tobias, Studer, Christoph

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 564 KB

english, 2015

20

Challenges in using the ToxRefDB as a resource for toxicity prediction modeling

Plunkett, Laura M., Kaplan, A. Michael, Becker, Richard A.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 265 KB

english, 2015

21

Use of an aggregate exposure model to estimate consumer exposure to fragrance ingredients in personal care and cosmetic products

Safford, B., Api, A.M., Barratt, C., Comiskey, D., Daly, E.J., Ellis, G., McNamara, C., O’Mahony, C., Robison, S., Smith, B., Thomas, R., Tozer, S.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.47 MB

english, 2015

22

Empirical characterisation of ranges of mainstream smoke toxicant yields from contemporary cigarette products using quantile regression methodology

Camacho, Oscar M., Eldridge, Alison, Proctor, Christopher J., McAdam, Kevin

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 4.08 MB

english, 2015

23

The molecular mechanisms of sodium metabisulfite on the expression of KATP and L-Ca2+ channels in rat hearts

Zhang, Quanxi, Bai, Yunlong, Yang, Zhenhua, Tian, Jingjing, Meng, Ziqiang

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.44 MB

english, 2015

24

Opinion of the Scientific Committee on Consumer Safety (SCCS) – The safety of the use of formaldehyde in nail hardeners

Bernauer, Ulrike, Coenraads, Pieter-Jan, Degen, Gisela H., Dusinska, Maria, Lilienblum, Werner, Luch, Andreas, Nielsen, Elsa, Platzek, Thomas, Rastogi, Suresh, Rousselle, Christophe, van Benthem, Jan,

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 203 KB

english, 2015

25

Impact of study design and database parameters on NOAEL distributions used for toxicological concern (TTC) values

Zarn, Jürg A., Hänggi, Emanuel, Engeli, Barbara E.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 800 KB

english, 2015

26

Adverse drug reactions for medicine newly approved in Japan from 1999 to 2013: Syncope/loss of consciousness and seizures/convulsions

Nagayama, Takashi

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 481 KB

english, 2015

27

Re the article “Incorporating potency into the EU classification for carcinogenicity and reproductive toxicity” by Hennes C et al. (Regulatory toxicology and Pharmacology, 70 (1024), 457–67)

Kelsey, J.R., Davison, P.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 191 KB

english, 2015

28

Analysis of workplace compliance measurements of asbestos by the U.S. Occupational Safety and Health Administration (1984–2011)

Cowan, Dallas M., Cheng, Thales J., Ground, Matthew, Sahmel, Jennifer, Varughese, Allysha, Madl, Amy K.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 840 KB

english, 2015

29

Analysis of EPA’s endocrine screening battery and recommendations for further review

Schapaugh, Adam W., McFadden, Lisa G., Zorrilla, Leah M., Geter, David R., Stuchal, Leah D., Sunger, Neha, Borgert, Christopher J.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 336 KB

english, 2015

30

Cover 2–Editorial Board

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 33 KB

english, 2015

31

Volume 72; Issue 3

Regulatory Toxicology and Pharmacology

Principles for identification of High Potency Category Chemicals for which the Dermal Sensitisation Threshold (DST) approach should not be applied

Extension of the Dermal Sensitisation Threshold (DST) approach to incorporate chemicals classified as reactive

Modernizing problem formulation for risk assessment necessitates articulation of mode of action

Comedications alter drug-induced liver injury reporting frequency: Data mining in the WHO VigiBase™

Novel database for exposure to fragrance ingredients in cosmetics and personal care products

Increasing Scientific Confidence in Adverse Outcome Pathways: Application of Tailored Bradford-Hill Considerations for Evaluating Weight of Evidence

Evaluation of Human Exposure to metals from some popular brands of underarm cosmetics in Nigeria

Safety evaluation of Angelica gigas: Genotoxicity and 13-weeks oral subchronic toxicity in rats

Clinical and anatomic pathology effects of serial blood sampling in rat toxicology studies, using conventional or microsampling methods

Developmental toxicity assessment of the new turf herbicide, methiozolin ([5-(2,6-difluorobenzyl)oxymethyl-5-methyl-3,3(3-methylthiophen-2-yl)-1,2-isoxazoline]), in rabbits

Classification of dermal sensitizers in pharmaceutical manufacturing

Mutagenicity and chemopreventive activities of Astronium species assessed by Ames test

A strategy for structuring and reporting a read-across prediction of toxicity

Non-animal photosafety screening for complex cosmetic ingredients with photochemical and photobiochemical assessment tools

In vitro metabolism of rebaudioside E under anaerobic conditions: Comparison with rebaudioside A

Bioaccessibility of micron-sized powder particles of molybdenum metal, iron metal, molybdenum oxides and ferromolybdenum – Importance of surface oxides

Novel analytical method to measure formaldehyde release from heated hair straightening cosmetic products: Impact on risk assessment

Threshold of toxicological concern (TTC) for developmental and reproductive toxicity of anticancer compounds

Sameness: The regulatory crux with nanomaterial identity and grouping schemes for hazard assessment

Challenges in using the ToxRefDB as a resource for toxicity prediction modeling

Use of an aggregate exposure model to estimate consumer exposure to fragrance ingredients in personal care and cosmetic products

Empirical characterisation of ranges of mainstream smoke toxicant yields from contemporary cigarette products using quantile regression methodology

The molecular mechanisms of sodium metabisulfite on the expression of KATP and L-Ca2+ channels in rat hearts

Opinion of the Scientific Committee on Consumer Safety (SCCS) – The safety of the use of formaldehyde in nail hardeners

Impact of study design and database parameters on NOAEL distributions used for toxicological concern (TTC) values

Adverse drug reactions for medicine newly approved in Japan from 1999 to 2013: Syncope/loss of consciousness and seizures/convulsions

Re the article “Incorporating potency into the EU classification for carcinogenicity and reproductive toxicity” by Hennes C et al. (Regulatory toxicology and Pharmacology, 70 (1024), 457–67)

Analysis of workplace compliance measurements of asbestos by the U.S. Occupational Safety and Health Administration (1984–2011)

Analysis of EPA’s endocrine screening battery and recommendations for further review

Cover 2–Editorial Board

Table of Contents