Volume 30; Issue 1

Main
Reproductive Toxicology
Volume 30; Issue 1

Reproductive Toxicology

Volume 30; Issue 1

1

Assessment of a recombinant androgen receptor binding assay: Initial steps towards validation

Alexius Freyberger, Marc Weimer, Hoai-Son Tran, Hans-Jürgen Ahr

Journal:

Reproductive Toxicology

Year:

2010

Language:

english

File:

PDF, 293 KB

english, 2010

2

Screening for (anti)androgenic properties using a standard operation protocol based on the human stably transfected androgen sensitive PALM cell line. First steps towards validation

A. Freyberger, H. Witters, M. Weimer, W. Lofink, P. Berckmans, H.-J. Ahr

Journal:

Reproductive Toxicology

Year:

2010

Language:

english

File:

PDF, 394 KB

english, 2010

3

Evaluation of a modified comet assay to detect DNA damage in mammalian sperm exposed in vitro to different mutagenic compounds

Paola Villani, Marcello Spanò, Francesca Pacchierotti, Marc Weimer, Eugenia Cordelli

Journal:

Reproductive Toxicology

Year:

2010

Language:

english

File:

PDF, 595 KB

english, 2010

4

Short-term dynamic culture of rat testicular fragments as a model to assess effects on steroidogenesis—Potential use and limitations

Alexius Freyberger, Marc Weimer, Wibke Lofink, Hans-Jürgen Ahr

Journal:

Reproductive Toxicology

Year:

2010

Language:

english

File:

PDF, 185 KB

english, 2010

5

ReProGlo: A new stem cell-based reporter assay aimed to predict embryotoxic potential of drugs and chemicals

Frederik Uibel, Annette Mühleisen, Christoph Köhle, Marc Weimer, Tina C. Stummann, Susanne Bremer, Michael Schwarz

Journal:

Reproductive Toxicology

Year:

2010

Language:

english

File:

PDF, 1.28 MB

english, 2010

6

Integrating (Q)SAR models, expert systems and read-across approaches for the prediction of developmental toxicity

M. Hewitt, C.M. Ellison, S.J. Enoch, J.C. Madden, M.T.D. Cronin

Journal:

Reproductive Toxicology

Year:

2010

Language:

english

File:

PDF, 214 KB

english, 2010

7

Assessment of a robust model protocol with accelerated throughput for a human recombinant full length estrogen receptor-α binding assay: Protocol optimization and intralaboratory assay performance as initial steps towards validation

Alexius Freyberger, Vickie Wilson, Marc Weimer, Shirlee Tan, Hoai-Son Tran, Hans-Jürgen Ahr

Journal:

Reproductive Toxicology

Year:

2010

Language:

english

File:

PDF, 527 KB

english, 2010

8

Quality assessment of a placental perfusion protocol

Line Mathiesen, Tina Mose, Thit Juul Mørck, Jeanette Kolstrup Søgaard Nielsen, Leif Kofoed Nielsen, Lisa Leth Maroun, Morten Hanefeld Dziegiel, Lise Grupe Larsen, Lisbeth Ehlert Knudsen

Journal:

Reproductive Toxicology

Year:

2010

Language:

english

File:

PDF, 455 KB

english, 2010

9

Transferability and inter-laboratory variability assessment of the in vitro bovine oocyte maturation (IVM) test within ReProTect

Alberto M. Luciano, Federica Franciosi, Valentina Lodde, Davide Corbani, Giovanna Lazzari, Gabriella Crotti, Cesare Galli, Cristian Pellizzer, Susanne Bremer, Marc Weimer, Silvia C. Modina

Journal:

Reproductive Toxicology

Year:

2010

Language:

english

File:

PDF, 342 KB

english, 2010

10

In vitro-Ishikawa cell test for assessing tissue-specific chemical effects on human endometrium

W.R. Schaefer, L. Fischer, W.R. Deppert, A. Hanjalic-Beck, L. Seebacher, M. Weimer, H.P. Zahradnik

Journal:

Reproductive Toxicology

Year:

2010

Language:

english

File:

PDF, 322 KB

english, 2010

11

Placental transport and in vitro effects of Bisphenol A

Thit J. Mørck, Giuseppina Sorda, Nicoletta Bechi, Brian S. Rasmussen, Jesper B. Nielsen, Francesca Ietta, Erik Rytting, Line Mathiesen, Luana Paulesu, Lisbeth E. Knudsen

Journal:

Reproductive Toxicology

Year:

2010

Language:

english

File:

PDF, 449 KB

english, 2010

12

The assessment of estrogenic or anti-estrogenic activity of chemicals by the human stably transfected estrogen sensitive MELN cell line: Results of test performance and transferability

H. Witters, A. Freyberger, K. Smits, C. Vangenechten, W. Lofink, M. Weimer, S. Bremer, P.H.-J. Ahr, P. Berckmans

Journal:

Reproductive Toxicology

Year:

2010

Language:

english

File:

PDF, 933 KB

english, 2010

13

Cell viability and PSA secretion assays in LNCaP cells: A tiered in vitro approach to screen chemicals with a prostate-mediated effect on male reproduction within the ReProTect project

Stefano Lorenzetti, Daniele Marcoccia, Laura Narciso, Alberto Mantovani

Journal:

Reproductive Toxicology

Year:

2010

Language:

english

File:

PDF, 1.15 MB

english, 2010

14

The test chemical selection procedure of the European Centre for the Validation of Alternative Methods for the EU Project ReProTect

Patricia Pazos, Cristian Pellizzer, Tina C. Stummann, Lars Hareng, Susanne Bremer

Journal:

Reproductive Toxicology

Year:

2010

Language:

english

File:

PDF, 689 KB

english, 2010

15

Preliminary interlaboratory comparison of the ex vivo dual human placental perfusion system

Päivi Myllynen, Line Mathiesen, Marc Weimer, Kirsi Annola, Elina Immonen, Vesa Karttunen, Maria Kummu, Thit Juul Mørck, Jeanette Kolstrup Søgaard Nielsen, Lisbeth Ehlert Knudsen, Kirsi Vähäkangas

Journal:

Reproductive Toxicology

Year:

2010

Language:

english

File:

PDF, 610 KB

english, 2010

16

Optimization and prevalidation of the in vitro ERα CALUX method to test estrogenic and antiestrogenic activity of compounds

Bart van der Burg, Roos Winter, Marc Weimer, Pascale Berckmans, Go Suzuki, Linda Gijsbers, Arjen Jonas, Sander van der Linden, Hilda Witters, Jac Aarts, Juliette Legler, Annette Kopp-Schneider, Susann

Journal:

Reproductive Toxicology

Year:

2010

Language:

english

File:

PDF, 651 KB

english, 2010

17

Optimization and prevalidation of the in vitro AR CALUX method to test androgenic and antiandrogenic activity of compounds

Bart van der Burg, Roos Winter, Hai-yen Man, Clea Vangenechten, Pascale Berckmans, Marc Weimer, Hilda Witters, Sander van der Linden

Journal:

Reproductive Toxicology

Year:

2010

Language:

english

File:

PDF, 407 KB

english, 2010

18

Unexpected common mechanistic pathways for embryotoxicity of warfarin and lovastatin

Karlfried Groebe, Katrin Hayess, Martina Klemm-Manns, Gerhard Schwall, Woijciech Wozny, Margino Steemans, Annelieke K. Peters, Chaturvedala Sastri, Petra Jaeckel, Werner Stegmann, Helmut Zengerling, R

Journal:

Reproductive Toxicology

Year:

2010

Language:

english

File:

PDF, 762 KB

english, 2010

19

Editorial

Aldert H. Piersma

Journal:

Reproductive Toxicology

Year:

2010

Language:

english

File:

PDF, 87 KB

english, 2010

20

The ReProTect Feasibility Study, a novel comprehensive in vitro approach to detect reproductive toxicants

Barbara Schenk, Marc Weimer, Susanne Bremer, Bart van der Burg, Rita Cortvrindt, Alexius Freyberger, Giovanna Lazzari, Cristian Pellizzer, Aldert Piersma, Wolfgang R. Schäfer, Andrea Seiler, Hilda Wit

Journal:

Reproductive Toxicology

Year:

2010

Language:

english

File:

PDF, 1.04 MB

english, 2010

21

Editorial Board Members

Journal:

Reproductive Toxicology

Year:

2010

Language:

english

File:

PDF, 56 KB

english, 2010

22

Metabolic activation capacity by primary hepatocytes expands the applicability of the embryonic stem cell test as alternative to experimental animal testing

Michael Hettwer, Marcos A. Reis-Fernandes, Marcus Iken, Michael Ott, Pablo Steinberg, Heinz Nau

Journal:

Reproductive Toxicology

Year:

2010

Language:

english

File:

PDF, 960 KB

english, 2010

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