Volume 9; Issue 1

Assay and Drug Development Technologies

Volume 9; Issue 1

1

Use of Base Modifications in Primers and Amplicons to Improve Nucleic Acids Detection in the Real-Time Snake Polymerase Chain Reaction

Kutyavin, Igor V.

Journal:

Assay and Drug Development Technologies

Year:

2011

Language:

english

File:

PDF, 692 KB

english, 2011

2

Virtual Ligand Screening of the National Cancer Institute (NCI) Compound Library Leads to the Allosteric Inhibitory Scaffolds of the West Nile Virus NS3 Proteinase

Shiryaev, Sergey A., Cheltsov, Anton V., Gawlik, Katarzyna, Ratnikov, Boris I., Strongin, Alex Y.

Journal:

Assay and Drug Development Technologies

Year:

2011

Language:

english

File:

PDF, 476 KB

english, 2011

3

Development of Cell-Based High-Throughput Assays for the Identification of Inhibitors of Receptor Activator of Nuclear Factor-Kappa B Signaling

Ashley, Jason W., McCoy, Erin M., Clements, Daniel A., Shi, Zhenqi, Chen, Taosheng, Feng, Xu

Journal:

Assay and Drug Development Technologies

Year:

2011

Language:

english

File:

PDF, 750 KB

english, 2011

4

Exchange Protein Directly Activated by Cyclic AMP Isoform 2 Is Not a Direct Target of Sulfonylurea Drugs

Tsalkova, Tamara, Gribenko, Alexey V., Cheng, Xiaodong

Journal:

Assay and Drug Development Technologies

Year:

2011

Language:

english

File:

PDF, 263 KB

english, 2011

5

Application of G Protein-Coupled Receptor-Heteromer Identification Technology to Monitor β -Arrestin Recruitment to G Protein-Coupled Receptor Heteromers

See, Heng B., Seeber, Ruth M., Kocan, Martina, Eidne, Karin A., Pfleger, Kevin D.G.

Journal:

Assay and Drug Development Technologies

Year:

2011

Language:

english

File:

PDF, 778 KB

english, 2011

6

Cell-Based Screening Using High-Throughput Flow Cytometry

Black, Christopher B., Duensing, Thomas D., Trinkle, Linda S., Dunlay, R. Terry

Journal:

Assay and Drug Development Technologies

Year:

2011

Language:

english

File:

PDF, 1.03 MB

english, 2011

7

Bioluminescence Assay for Detecting Cell Surface Membrane Protein Expression

Kato, Mieko, Chiba, Tomoki, Li, Min, Hanyu, Yoshiro

Journal:

Assay and Drug Development Technologies

Year:

2011

Language:

english

File:

PDF, 412 KB

english, 2011

8

Using a Genetically Encoded Fluorescent Amino Acid as a Site-Specific Probe to Detect Binding of Low-Molecular-Weight Compounds

Ugwumba, Isaac N., Ozawa, Kiyoshi, de la Cruz, Laura, Xu, Zhi-Qiang, Herlt, Anthony J., Hadler, Kieran S., Coppin, Chris, Brown, Susan E., Schenk, Gerhard, Oakeshott, John G., Otting, Gottfried

Journal:

Assay and Drug Development Technologies

Year:

2011

Language:

english

File:

PDF, 483 KB

english, 2011

9

Literature Search and Review

Auld, Doug, Simeonov, Anton, Thomas, Craig, Lea, Wendy

Journal:

Assay and Drug Development Technologies

Year:

2011

Language:

english

File:

PDF, 1.17 MB

english, 2011

10

A Predictive Nuclear Translocation Assay for Spliced X-Box–Binding Protein 1 Identifies Compounds with Known Organ Toxicities

Hahmann, Christa, Weiser, Amiee, Duckett, Derek, Schroeter, Thomas

Journal:

Assay and Drug Development Technologies

Year:

2011

Language:

english

File:

PDF, 488 KB

english, 2011