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Volume 14; Issue 2
Main
The AAPS Journal
Volume 14; Issue 2
The AAPS Journal
Volume 14; Issue 2
1
Challenges in Development of Targeted Liposomal Therapeutics
Rupa R. Sawant
,
Vladimir P. Torchilin
Journal:
The AAPS Journal
Year:
2012
Language:
english
File:
PDF, 393 KB
Your tags:
english, 2012
2
Pharmacokinetics, Lymph Node Uptake, and Mechanistic PK Model of Near-Infrared Dye-Labeled Bevacizumab After IV and SC Administration in Mice
Fang Wu
,
Mitalee Tamhane
,
Marilyn E. Morris
Journal:
The AAPS Journal
Year:
2012
Language:
english
File:
PDF, 323 KB
Your tags:
english, 2012
3
A mechanism-Based Approach for Absorption Modeling: The Gastro-Intestinal Transit Time (GITT) Model
Emilie Hénin
,
Martin Bergstrand
,
Joseph F. Standing
,
Mats O. Karlsson
Journal:
The AAPS Journal
Year:
2012
Language:
english
File:
PDF, 470 KB
Your tags:
english, 2012
4
Pharmacokinetic Evaluation of Intranasally Administered Vinyl Polymer-Coated Lorazepam Microparticles in Rabbits
Yanjun Zhao
,
Marc B. Brown
,
Rajeshree H. Khengar
,
Matthew J. Traynor
,
Pedro Barata
,
Stuart A. Jones
Journal:
The AAPS Journal
Year:
2012
Language:
english
File:
PDF, 145 KB
Your tags:
english, 2012
5
Benet L Z and Galeazzi R L: Noncompartmental Determination of the Steady-State Volume of Distribution,J Pharm Sci68, 1071–1074, 1979—the Backstory
Leslie Z. Benet
Journal:
The AAPS Journal
Year:
2012
Language:
english
File:
PDF, 96 KB
Your tags:
english, 2012
6
Rapid Sample Size Calculations for a Defined Likelihood Ratio Test-Based Power in Mixed-Effects Models
Camille Vong
,
Martin Bergstrand
,
Joakim Nyberg
,
Mats O. Karlsson
Journal:
The AAPS Journal
Year:
2012
Language:
english
File:
PDF, 602 KB
Your tags:
english, 2012
7
Population Analyses of Efficacy and Safety of ABT-594 in Subjects with Diabetic Peripheral Neuropathic Pain
Sandeep Dutta
,
Balakrishna S. Hosmane
,
Walid M. Awni
Journal:
The AAPS Journal
Year:
2012
Language:
english
File:
PDF, 312 KB
Your tags:
english, 2012
8
Design and Characterization of Novel Peptide-Coated Lipid Nanoparticles for Targeting Anti-HIV Drug to CD4 Expressing Cells
Aaron N. Endsley
,
Rodney J. Y. Ho
Journal:
The AAPS Journal
Year:
2012
Language:
english
File:
PDF, 355 KB
Your tags:
english, 2012
9
Cutaneous Microdialysis: Cytokine Evidence for Altered Innate Reactivity in the Skin of Psoriasis Patients?
Florence Sjögren
,
Karin Davidsson
,
Michael Sjöström
,
Chris D. Anderson
Journal:
The AAPS Journal
Year:
2012
Language:
english
File:
PDF, 531 KB
Your tags:
english, 2012
10
Applications of Human Pharmacokinetic Prediction in First-in-Human Dose Estimation
Peng Zou
,
Yanke Yu
,
Nan Zheng
,
Yongsheng Yang
,
Hayley J. Paholak
,
Lawrence X. Yu
,
Duxin Sun
Journal:
The AAPS Journal
Year:
2012
Language:
english
File:
PDF, 442 KB
Your tags:
english, 2012
11
An Investigation into the Utility of a Multi-compartmental, Dynamic, System of the Upper Gastrointestinal Tract to Support Formulation Development and Establish Bioequivalence of Poorly Soluble Drugs
Paul A. Dickinson
,
Ragheb Abu Rmaileh
,
Lee Ashworth
,
Richard A. Barker
,
Wendy M. Burke
,
Claire M. Patterson
,
Nick Stainforth
,
Mohammed Yasin
Journal:
The AAPS Journal
Year:
2012
Language:
english
File:
PDF, 494 KB
Your tags:
english, 2012
12
Ligand Binding Assays in the 21st Century Laboratory: Recommendations for Characterization and Supply of Critical Reagents
Denise M. O’Hara
,
Valerie Theobald
,
Adrienne Clements Egan
,
Joel Usansky
,
Murli Krishna
,
Julie TerWee
,
Mauricio Maia
,
Frank P. Spriggs
,
John Kenney
,
Afshin Safavi
,
Jeannine Keefe
Journal:
The AAPS Journal
Year:
2012
Language:
english
File:
PDF, 581 KB
Your tags:
english, 2012
13
Issues and Challenges of Subvisible and Submicron Particulate Analysis in Protein Solutions
Thomas M. Scherer
,
Stephenie Leung
,
Laura Owyang
,
Steven J. Shire
Journal:
The AAPS Journal
Year:
2012
Language:
english
File:
PDF, 408 KB
Your tags:
english, 2012
14
Conformational Analysis of Therapeutic Proteins by Hydroxyl Radical Protein Footprinting
Caroline Watson
,
Joshua S. Sharp
Journal:
The AAPS Journal
Year:
2012
Language:
english
File:
PDF, 574 KB
Your tags:
english, 2012
15
The Solubility–Permeability Interplay and Its Implications in Formulation Design and Development for Poorly Soluble Drugs
Arik Dahan
,
Jonathan M. Miller
Journal:
The AAPS Journal
Year:
2012
Language:
english
File:
PDF, 396 KB
Your tags:
english, 2012
16
Role of Metabolism in the Effects of Genistein and Its Phase II Conjugates on the Growth of Human Breast Cell Lines
Bo Yuan
,
Linglan Wang
,
Yi Jin
,
Huijuan Zhen
,
Pingwei Xu
,
Youjun Xu
,
Chibing Li
,
Haiyan Xu
Journal:
The AAPS Journal
Year:
2012
Language:
english
File:
PDF, 1.00 MB
Your tags:
english, 2012
17
Challenges in Development of Nanoparticle-Based Therapeutics
Neil Desai
Journal:
The AAPS Journal
Year:
2012
Language:
english
File:
PDF, 466 KB
Your tags:
english, 2012
18
Immunogenicity to Therapeutic Proteins: Impact on PK/PD and Efficacy
Narendra Chirmule
,
Vibha Jawa
,
Bernd Meibohm
Journal:
The AAPS Journal
Year:
2012
Language:
english
File:
PDF, 187 KB
Your tags:
english, 2012
19
Acarbose Bioequivalence: Exploration of New Pharmacodynamic Parameters
Min Zhang
,
Jin Yang
,
Lei Tao
,
Lingjun Li
,
Pengcheng Ma
,
John Paul Fawcett
Journal:
The AAPS Journal
Year:
2012
Language:
english
File:
PDF, 183 KB
Your tags:
english, 2012
20
Mechanism-Based Pharmacokinetic/Pharmacodynamic Modeling of Rat Prefrontal Cortical Dopamine Response to Dual Acting Norepinephrine Reuptake Inhibitor and 5-HT1APartial Agonist
Cheryl Shuang-wu Li
,
Liming Zhang
,
Taraneh Haske
,
Amy Dounay
,
David Gray
,
Nancy Barta
,
Joanne Brodfuehrer
,
Christopher Lepsy
,
Brian Campbell
Journal:
The AAPS Journal
Year:
2012
Language:
english
File:
PDF, 670 KB
Your tags:
english, 2012
21
A Physiologically Based Pharmacokinetic Model of Mitoxantrone in Mice and Scale-up to Humans: a Semi-Mechanistic Model Incorporating DNA and Protein Binding
Guohua An
,
Marilyn E. Morris
Journal:
The AAPS Journal
Year:
2012
Language:
english
File:
PDF, 559 KB
Your tags:
english, 2012
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