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Volume 21; Issue 4
Main
The AAPS Journal
Volume 21; Issue 4
The AAPS Journal
Volume 21; Issue 4
1
Fetal Concentrations of Budesonide and Fluticasone Propionate: a Study in Mice
Zaidi, Syedsaoud
,
Chen, Mong-Jen
,
Lee, Daniel T.
,
Neubart, Elsa
,
Ewing, Pär
,
Miller-Larsson, Anna
,
Hochhaus, Günther
Journal:
The AAPS Journal
Year:
2019
Language:
english
File:
PDF, 945 KB
Your tags:
english, 2019
2
In Vitro and In Vivo Co-delivery of siRNA and Doxorubicin by Folate-PEG-Appended Dendrimer/Glucuronylglucosyl-β-Cyclodextrin Conjugate
Mohammed, Ahmed Fouad Abdelwahab
,
Higashi, Taishi
,
Motoyama, Keiichi
,
Ohyama, Ayumu
,
Onodera, Risako
,
Khaled, Khaled Ali
,
Sarhan, Hatem Abdelmonsef
,
Hussein, Amal Kamal
,
Arima, Hidetoshi
Journal:
The AAPS Journal
Year:
2019
Language:
english
File:
PDF, 1.60 MB
Your tags:
english, 2019
3
Towards Improved Pharmacokinetic Models for the Analysis of Transporter-Mediated Hepatic Disposition of Drug Molecules with Positron Emission Tomography
Hernández Lozano, Irene
,
Karch, Rudolf
,
Bauer, Martin
,
Blaickner, Matthias
,
Matsuda, Akihiro
,
Wulkersdorfer, Beatrix
,
Hacker, Marcus
,
Zeitlinger, Markus
,
Langer, Oliver
Journal:
The AAPS Journal
Year:
2019
Language:
english
File:
PDF, 2.26 MB
Your tags:
english, 2019
4
Targeting Cancer Via Resveratrol-Loaded Nanoparticles Administration: Focusing on In Vivo Evidence
Santos, Ana Cláudia
,
Pereira, Irina
,
Magalhães, Mariana
,
Pereira-Silva, Miguel
,
Caldas, Mariana
,
Ferreira, Laura
,
Figueiras, Ana
,
Ribeiro, António J.
,
Veiga, Francisco
Journal:
The AAPS Journal
Year:
2019
File:
PDF, 1.69 MB
Your tags:
2019
5
Fc-Fusion Drugs Have FcγR/C1q Binding and Signaling Properties That May Affect Their Immunogenicity
Lagassé, H. A. Daniel
,
Hengel, Hartmut
,
Golding, Basil
,
Sauna, Zuben E.
Journal:
The AAPS Journal
Year:
2019
Language:
english
File:
PDF, 2.52 MB
Your tags:
english, 2019
6
A Novel Method for Analysing Frequent Observations from Questionnaires in Order to Model Patient-Reported Outcomes: Application to EXACT® Daily Diary Data from COPD Patients
Germovsek, Eva
,
Ambery, Claire
,
Yang, Shuying
,
Beerahee, Misba
,
Karlsson, Mats O.
,
Plan, Elodie L.
Journal:
The AAPS Journal
Year:
2019
Language:
english
File:
PDF, 1.42 MB
Your tags:
english, 2019
7
In Vitro Metabolism and Hepatic Intrinsic Clearance of the Synthetic Cannabinoid Receptor Agonist JWH-122 and Its Four ω-Halogenated Analogues
Davidsen, Anders Bork
,
Mardal, Marie
,
Linnet, Kristian
Journal:
The AAPS Journal
Year:
2019
Language:
english
File:
PDF, 1.18 MB
Your tags:
english, 2019
8
Application of Mechanistic Ocular Absorption Modeling and Simulation to Understand the Impact of Formulation Properties on Ophthalmic Bioavailability in Rabbits: a Case Study Using Dexamethasone Suspension
Le Merdy, Maxime
,
Fan, Jianghong
,
Bolger, Michael B.
,
Lukacova, Viera
,
Spires, Jessica
,
Tsakalozou, Eleftheria
,
Patel, Vikram
,
Xu, Lin
,
Stewart, Sharron
,
Chockalingam, Ashok
,
Narayanasamy, Suresh
,
Rou
Journal:
The AAPS Journal
Year:
2019
Language:
english
File:
PDF, 3.51 MB
Your tags:
english, 2019
9
Population Pharmacokinetic Modeling in the Presence of Missing Time-Dependent Covariates: Impact of Body Weight on Pharmacokinetics of Paracetamol in Neonates
Krzyzanski, Wojciech
,
Cook, Sarah F.
,
Wilbaux, Melanie
,
Sherwin, Catherine M. T.
,
Allegaert, Karel
,
Vermeulen, An
,
van den Anker, John N.
Journal:
The AAPS Journal
Year:
2019
Language:
english
File:
PDF, 1.25 MB
Your tags:
english, 2019
10
Mind the Gaps: Ontogeny of Human Brain P-gp and Its Impact on Drug Toxicity
Nicolas, Jean-Marie
,
de Lange, Elizabeth C. M.
Journal:
The AAPS Journal
Year:
2019
Language:
english
File:
PDF, 921 KB
Your tags:
english, 2019
11
Translational Quantitative Systems Pharmacology in Drug Development: from Current Landscape to Good Practices
Bai, Jane P. F.
,
Earp, Justin C.
,
Pillai, Venkateswaran C.
Journal:
The AAPS Journal
Year:
2019
Language:
english
File:
PDF, 899 KB
Your tags:
english, 2019
12
Anti-drug Antibody Assay Conditions Significantly Impact Assay Screen and Confirmatory Cut-Points
Gorovits, Boris
,
Wang, Ying
,
Zhu, Liang
,
Araya, Marcela
,
Kamerud, John
,
Lepsy, Christopher
Journal:
The AAPS Journal
Year:
2019
Language:
english
File:
PDF, 1.19 MB
Your tags:
english, 2019
13
Estimating In Vivo Fractional Contribution of OATP1B1 to Human Hepatic Active Uptake by Mechanistically Modeling Pharmacogenetic Data
Li, Rui
Journal:
The AAPS Journal
Year:
2019
Language:
english
File:
PDF, 900 KB
Your tags:
english, 2019
14
Correction to: A Translational Quantitative Systems Pharmacology Model for CD3 Bispecific Molecules: Application to Quantify T Cell-Mediated Tumor Cell Killing by P-Cadherin LP DART®
Betts, Alison
,
Haddish-Berhane, Nahor
,
Shah, Dhaval K.
,
van der Graaf, Piet H.
,
Barletta, Frank
,
King, Lindsay
,
Clark, Tracey
,
Kamperschroer, Cris
,
Root, Adam
,
Hooper, Andrea
,
Chen, Xiaoying
Journal:
The AAPS Journal
Year:
2019
Language:
english
File:
PDF, 717 KB
Your tags:
english, 2019
15
Application of Mechanistic Ocular Absorption Modeling and Simulation to Understand the Impact of Formulation Properties on Ophthalmic Bioavailability in Rabbits: a Case Study Using Dexamethasone Suspension
Le Merdy, Maxime
,
Fan, Jianghong
,
Bolger, Michael B.
,
Lukacova, Viera
,
Spires, Jessica
,
Tsakalozou, Eleftheria
,
Patel, Vikram
,
Xu, Lin
,
Stewart, Sharron
,
Chockalingam, Ashok
,
Narayanasamy, Suresh
,
Rou
Journal:
The AAPS Journal
Year:
2019
File:
PDF, 3.51 MB
Your tags:
2019
16
Population Pharmacokinetic Modeling in the Presence of Missing Time-Dependent Covariates: Impact of Body Weight on Pharmacokinetics of Paracetamol in Neonates
Krzyzanski, Wojciech
,
Cook, Sarah F.
,
Wilbaux, Melanie
,
Sherwin, Catherine M. T.
,
Allegaert, Karel
,
Vermeulen, An
,
van den Anker, John N.
Journal:
The AAPS Journal
Year:
2019
File:
PDF, 1.25 MB
Your tags:
2019
17
Mind the Gaps: Ontogeny of Human Brain P-gp and Its Impact on Drug Toxicity
Nicolas, Jean-Marie
,
de Lange, Elizabeth C. M.
Journal:
The AAPS Journal
Year:
2019
File:
PDF, 921 KB
Your tags:
2019
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