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Volume 22; Issue 3
Main
The AAPS Journal
Volume 22; Issue 3
The AAPS Journal
Volume 22; Issue 3
1
Applying Beta Distribution in Analyzing Bounded Outcome Score Data
Hu, Chuanpu
,
Zhou, Honghui
,
Sharma, Amarnath
Journal:
The AAPS Journal
Year:
2020
Language:
english
File:
PDF, 542 KB
Your tags:
english, 2020
2
Optimal Sampling Strategies for Irinotecan (CPT-11) and its Active Metabolite (SN-38) in Cancer Patients
Karas, Spinel
,
Etheridge, Amy S.
,
Tsakalozou, Eleftheria
,
RamÃrez, Jacqueline
,
Cecchin, Erika
,
van Schaik, Ron H.N.
,
Toffoli, Giuseppe
,
Ratain, Mark J.
,
Mathijssen, Ron H.J.
,
Forrest, Alan
,
Bies, Rob
Journal:
The AAPS Journal
Year:
2020
Language:
english
File:
PDF, 1.80 MB
Your tags:
english, 2020
3
Machine Learning Analysis of Individual Tumor Lesions in Four Metastatic Colorectal Cancer Clinical Studies: Linking Tumor Heterogeneity to Overall Survival
Vera-Yunca, Diego
,
Girard, Pascal
,
Parra-Guillen, Zinnia P.
,
Munafo, Alain
,
Trocóniz, Iñaki F.
,
Terranova, Nadia
Journal:
The AAPS Journal
Year:
2020
Language:
english
File:
PDF, 1.59 MB
Your tags:
english, 2020
4
Correction to: Development and Utility of an ELISA Method for Sensitive and Specific Detection of IgE Antidrug Antibodies
Jiang, Lynn L.
,
Khandelwal, Puneet
,
Clarke, Adam W.
,
Bakhtiar, Ray
,
Zou, Linglong
,
Zhong, Zhandong Don
Journal:
The AAPS Journal
Year:
2020
Language:
english
File:
PDF, 163 KB
Your tags:
english, 2020
5
Clinical Immunogenicity Risk Assessment Strategy for a Low Risk Monoclonal Antibody
Kernstock, Robert
,
Sperinde, Gizette
,
Finco, Deborah
,
Davis, Roslyn
,
Montgomery, Diana
Journal:
The AAPS Journal
Year:
2020
Language:
english
File:
PDF, 405 KB
Your tags:
english, 2020
6
Structure-Based Design and Discovery of a Long-Acting Cocaine Hydrolase Mutant with Improved Binding Affinity to Neonatal Fc Receptor for Treatment of Cocaine Abuse
Zheng, Fang
,
Chen, Xiabin
,
Kim, Kyungbo
,
Zhang, Ting
,
Huang, Haifeng
,
Zhou, Shuo
,
Zhang, Jinling
,
Jin, Zhenyu
,
Zhan, Chang-Guo
Journal:
The AAPS Journal
Year:
2020
Language:
english
File:
PDF, 1.04 MB
Your tags:
english, 2020
7
Subcutaneous Site-of-Absorption Study with the Monoclonal Antibody Tocilizumab in Minipigs: Administration Behind Ear Translates Best to Humans
Richter, Wolfgang F.
,
Grimm, Hans-Peter
,
Gouy, Marie-Hélène
,
Søgaard, Susi
,
Kreuzer, Caroline
,
Wessels, Uwe
,
Draganov, Dragomir
,
Muenzer, Chris
,
Hoche, Tonio
Journal:
The AAPS Journal
Year:
2020
File:
PDF, 565 KB
Your tags:
2020
8
Clinical Immunogenicity Risk Assessment for a Fusion Protein
Sperinde, Gizette
,
Montgomery, Diana
,
Mytych, Daniel T.
Journal:
The AAPS Journal
Year:
2020
File:
PDF, 252 KB
Your tags:
2020
9
Development of a FRET-Based Assay for Analysis of mAbs Internalization and Processing by Dendritic Cells in Preclinical Immunogenicity Risk Assessment
Wen, Yi
,
Cahya, Suntara
,
Zeng, Wei
,
Lin, Joanne
,
Wang, Xiaoli
,
Liu, Ling
,
Malherbe, Laurent
,
Siegel, Robert
,
Ferrante, Andrea
,
Kaliyaperumal, Arunan
Journal:
The AAPS Journal
Year:
2020
File:
PDF, 733 KB
Your tags:
2020
10
Immunogenicity Risk Assessment for an Engineered Human Cytokine Analogue Expressed in Different Cell Substrates
Chamberlain, Paul
,
Rup, Bonita
Journal:
The AAPS Journal
Year:
2020
File:
PDF, 415 KB
Your tags:
2020
11
Comparison of Alternative Population Modeling Approaches for Implementing a Level A IVIVC and for Assessing the Time-Scaling Factor Using Deconvolution and Convolution-Based Methods
Gomeni, Roberto
,
Bressolle-Gomeni, Françoise
Journal:
The AAPS Journal
Year:
2020
File:
PDF, 788 KB
Your tags:
2020
12
A Translational Physiologically Based Pharmacokinetics/Pharmacodynamics Framework of Target-Mediated Disposition, Target Inhibition and DrugâDrug Interactions of Bortezomib
Iwasaki, Shinji
,
Zhu, Andy
,
Hanley, Michael
,
Venkatakrishnan, Karthik
,
Xia, Cindy
Journal:
The AAPS Journal
Year:
2020
File:
PDF, 553 KB
Your tags:
2020
13
Quality by DesignâBased Assessment for Analytical Similarity of Adalimumab Biosimilar HLX03 to Humira®
Zhang, Erhui
,
Xie, Liqi
,
Qin, Peilan
,
Lu, Lihong
,
Xu, Yanpeng
,
Gao, Wenyuan
,
Wang, Linlin
,
Xie, Michael Hongwei
,
Jiang, Weidong
,
Liu, Scott
Journal:
The AAPS Journal
Year:
2020
File:
PDF, 1.89 MB
Your tags:
2020
14
Modeling Temperature-Dependent Dermal Absorption and Clearance for Transdermal and Topical Drug Applications
LaCount, Terri D.
,
Zhang, Qian
,
Hao, Jinsong
,
Ghosh, Priyanka
,
Raney, Sam G
,
Talattof, Arjang
,
Kasting, Gerald B.
,
Li, S. Kevin
Journal:
The AAPS Journal
Year:
2020
File:
PDF, 929 KB
Your tags:
2020
15
Drug Absorption Parameters Obtained Using the Isolated Perfused Rat Lung Model Are Predictive of Rat In Vivo Lung Absorption
Eriksson, Johanna
,
Sjögren, Erik
,
Lennernäs, Hans
,
Thörn, Helena
Journal:
The AAPS Journal
Year:
2020
File:
PDF, 1.70 MB
Your tags:
2020
16
Why Do the Majority of Submissions for Bridging from a Prefilled Syringe to an Autoinjector Include Bioequivalence Studies in Order to Demonstrate Comparability?
Lambert, William J.
Journal:
The AAPS Journal
Year:
2020
File:
PDF, 181 KB
Your tags:
2020
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