Volume 178; Issue 2

The American Journal of Pathology

Volume 178; Issue 2

1

Regulation of Biliary Proliferation by Neuroendocrine Factors: Implications for the Pathogenesis of Cholestatic Liver Diseases

Md Kamruzzaman Munshi, Sally Priester, Eugenio Gaudio, Fuquan Yang, Gianfranco Alpini, Romina Mancinelli, Candace Wise, Fanyn Meng, Antonio Franchitto, Paolo Onori, Shannon S. Glaser

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 1.20 MB

english, 2011

2

Activation-Induced Cytidine Deaminase and Aberrant Germinal Center Selection in the Development of Humoral Autoimmunities

Ahmad Zaheen, Alberto Martin

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 663 KB

english, 2011

3

Rear Polarization of the Microtubule-Organizing Center in Neointimal Smooth Muscle Cells Depends on PKCα, ARPC5, and RHAMM

Rosalind Silverman-Gavrila, Lorelei Silverman-Gavrila, Guangpei Hou, Ming Zhang, Milton Charlton, Michelle P. Bendeck

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 4.00 MB

english, 2011

4

Arachidonic Acid Pathway Members PLA2G7, HPGD, EPHX2, and CYP4F8 Identified as Putative Novel Therapeutic Targets in Prostate Cancer

Paula Vainio, Santosh Gupta, Kirsi Ketola, Tuomas Mirtti, John-Patrick Mpindi, Pekka Kohonen, Vidal Fey, Merja Perälä, Frank Smit, Gerald Verhaegh, Jack Schalken, Kalle A. Alanen, Olli Kallioniemi, Kr

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 2.78 MB

english, 2011

5

Mast Cells Are an Essential Component of Human Radiation Proctitis and Contribute to Experimental Colorectal Damage in Mice

Karl Blirando, Fabien Milliat, Isabelle Martelly, Jean-Christophe Sabourin, Marc Benderitter, Agnès François

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 3.38 MB

english, 2011

6

A Mouse Model of β-Thalassemia Shows a Liver-Specific Down-Regulation of Abcc6 Expression

Ludovic Martin, Vanessa Douet, Christopher M. VanWart, Matthew B. Heller, Olivier Le Saux

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 1.21 MB

english, 2011

7

Reduced Stathmin-1 Expression in Natural Killer Cells Associated with Spontaneous Abortion

Yi Lin, Cui Li, Bin Shan, Wenjing Wang, Shigeru Saito, Jiehan Xu, Jingfang Di, Yanmin Zhong, Da-Jin Li

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 2.09 MB

english, 2011

8

Elastin Degradation and Vascular Smooth Muscle Cell Phenotype Change Precede Cell Loss and Arterial Medial Calcification in a Uremic Mouse Model of Chronic Kidney Disease

Ashwini Pai, Elizabeth M. Leaf, Mohga El-Abbadi, Cecilia M. Giachelli

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 1.74 MB

english, 2011

9

IGF-1 Has Plaque-Stabilizing Effects in Atherosclerosis by Altering Vascular Smooth Muscle Cell Phenotype

Jan H. von der Thüsen, Keren S. Borensztajn, Silvia Moimas, Sandra van Heiningen, Peter Teeling, Theo J.C. van Berkel, Erik A.L. Biessen

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 2.18 MB

english, 2011

10

Platelet-Activating Factor Blockade Inhibits the T-Helper Type 17 Cell Pathway and Suppresses Psoriasis-Like Skin Disease in K5.hTGF-β1 Transgenic Mice

Tej Pratap Singh, Barbara Huettner, Harald Koefeler, Gerlinde Mayer, Isabella Bambach, Katrin Wallbrecht, Michael P. Schön, Peter Wolf

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 1.79 MB

english, 2011

11

Basigin/CD147 Promotes Renal Fibrosis after Unilateral Ureteral Obstruction

Noritoshi Kato, Tomoki Kosugi, Waichi Sato, Takuji Ishimoto, Hiroshi Kojima, Yuka Sato, Kazuma Sakamoto, Shoichi Maruyama, Yukio Yuzawa, Seiichi Matsuo, Kenji Kadomatsu

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 1.35 MB

english, 2011

12

Expression of Hypoxic Marker CA IX Is Regulated by Site-Specific DNA Methylation and Is Associated with the Histology of Gastric Cancer

Jun Nakamura, Yoshihiko Kitajima, Keita Kai, Kazuyoshi Hashiguchi, Masatsugu Hiraki, Hirokazu Noshiro, Kohji Miyazaki

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 2.23 MB

english, 2011

13

Differential Distribution and Phenotype of Decidual Macrophages in Preeclamptic versus Control Pregnancies

Dorrith Schonkeren, Marie-Louise van der Hoorn, Padmini Khedoe, Godelieve Swings, Els van Beelen, Frans Claas, Cees van Kooten, Emile de Heer, Sicco Scherjon

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 1.44 MB

english, 2011

14

Targeting Endothelium-Pericyte Cross Talk by Inhibiting VEGF Receptor Signaling Attenuates Kidney Microvascular Rarefaction and Fibrosis

Shuei-Liong Lin, Fan-Chi Chang, Claudia Schrimpf, Yi-Ting Chen, Ching-Fang Wu, Vin-Cent Wu, Wen-Chih Chiang, Frank Kuhnert, Calvin J. Kuo, Yung-Ming Chen, Kwan-Dun Wu, Tun-Jun Tsai, Jeremy S. Duffield

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 4.29 MB

english, 2011

15

The IL-27 Receptor Has Biphasic Effects in Crescentic Glomerulonephritis Mediated Through Th1 Responses

Shaun A. Summers, Richard K.S. Phoon, Joshua D. Ooi, Stephen R. Holdsworth, A. Richard Kitching

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 3.61 MB

english, 2011

16

Overexpression of Pigment Epithelium–Derived Factor Inhibits Retinal Inflammation and Neovascularization

Kyoungmin Park, Ji Jin, Yang Hu, Kevin Zhou, Jian-xing Ma

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 2.13 MB

english, 2011

17

Tenascin C Induces Epithelial-Mesenchymal Transition–Like Change Accompanied by SRC Activation and Focal Adhesion Kinase Phosphorylation in Human Breast Cancer Cells

Keiki Nagaharu, Xinhui Zhang, Toshimichi Yoshida, Daisuke Katoh, Noriko Hanamura, Yuji Kozuka, Tomoko Ogawa, Taizo Shiraishi, Kyoko Imanaka-Yoshida

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 3.06 MB

english, 2011

18

IgG Autoantibodies Against Desmocollin 3 in Pemphigus Sera Induce Loss of Keratinocyte Adhesion

David Rafei, Ralf Müller, Norito Ishii, Maria Llamazares, Takashi Hashimoto, Michael Hertl, Rüdiger Eming

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 1.12 MB

english, 2011

19

Gastrin-Releasing Peptide Signaling Alters Colon Cancer Invasiveness via Heterochromatin Protein 1Hsβ

Robert Tell, Claudio A. Rivera, Jillian Eskra, Lauren N. Taglia, Adam Blunier, Q. Tian Wang, Richard V. Benya

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 1.33 MB

english, 2011

20

Administration of Pigment Epithelium-Derived Factor Inhibits Left Ventricular Remodeling and Improves Cardiac Function in Rats with Acute Myocardial Infarction

Shin-ichiro Ueda, Sho-ichi Yamagishi, Takanori Matsui, Yuko Jinnouchi, Tsutomu Imaizumi

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 1.69 MB

english, 2011

21

A Quantitative Approach to Scar Analysis

Hooman Khorasani, Zhong Zheng, Calvin Nguyen, Janette Zara, Xinli Zhang, Joyce Wang, Kang Ting, Chia Soo

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 1.97 MB

english, 2011

22

Genome-Wide Expression Analysis of Middle Eastern Colorectal Cancer Reveals FOXM1 as a Novel Target for Cancer Therapy

Shahab Uddin, Maqbool Ahmed, Azhar Hussain, Jehad Abubaker, Nasser Al-Sanea, Alaa AbdulJabbar, Luai H. Ashari, Samar Alhomoud, Fouad Al-Dayel, Zeenath Jehan, Prashant Bavi, Abdul K. Siraj, Khawla S. A

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 2.34 MB

english, 2011

23

UV-B Radiation Induces Macrophage Migration Inhibitory Factor–Mediated Melanogenesis through Activation of Protease-Activated Receptor-2 and Stem Cell Factor in Keratinocytes

Akiko Enomoto, Yoko Yoshihisa, Takako Yamakoshi, Mati Ur Rehman, Osamu Norisugi, Hiroshi Hara, Kenji Matsunaga, Teruhiko Makino, Jun Nishihira, Tadamichi Shimizu

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 1.56 MB

english, 2011

24

IL-10–Producing Regulatory B10 Cells Inhibit Intestinal Injury in a Mouse Model

Koichi Yanaba, Ayumi Yoshizaki, Yoshihide Asano, Takafumi Kadono, Thomas F. Tedder, Shinichi Sato

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 1.77 MB

english, 2011

25

DNA Methylation Suppresses Expression of the Urea Cycle Enzyme Carbamoyl Phosphate Synthetase 1 (CPS1) in Human Hepatocellular Carcinoma

Hongyan Liu, Huijia Dong, Keith Robertson, Chen Liu

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 2.29 MB

english, 2011

26

Bone Marrow–Derived Progenitor Cells Do Not Contribute to Podocyte Turnover in the Puromycin Aminoglycoside and Renal Ablation Models in Rats

Catherine Meyer-Schwesinger, Claudia Lange, Verena Bröcker, Putri Andina Agustian, Ulrich Lehmann, Annette Raabe, Martina Brinkmeyer, Eiji Kobayashi, Mario Schiffer, Guntram Büsche, Hans H. Kreipe, Fr

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 713 KB

english, 2011

27

CD14 Signaling Reciprocally Controls Collagen Deposition and Turnover to Regulate the Development of Lyme Arthritis

Bikash Sahay, Anju Singh, Arumugam Gnanamani, Rebeca L. Patsey, J. Edwin Blalock, Timothy J. Sellati

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 2.22 MB

english, 2011

28

Isolation and Characterization of Progenitor-Like Cells from Human Renal Proximal Tubules

David Lindgren, Anna-Karin Boström, Kristina Nilsson, Jennifer Hansson, Jonas Sjölund, Christina Möller, Karin Jirström, Elise Nilsson, Göran Landberg, Håkan Axelson, Martin E. Johansson

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 4.74 MB

english, 2011

29

Antigen Presentation and MHC Class II Expression by Human Esophageal Epithelial Cells: Role in Eosinophilic Esophagitis

Daniel J. Mulder, Aman Pooni, Nanette Mak, David J. Hurlbut, Sameh Basta, Christopher J. Justinich

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 1.83 MB

english, 2011

30

Serotonin Activates Dendritic Cell Function in the Context of Gut Inflammation

Nan Li, Jean-Eric Ghia, Huaqing Wang, Jessica McClemens, Francine Cote, Youko Suehiro, Jacques Mallet, Waliul I. Khan

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 1.65 MB

english, 2011

31

Increased Expression of P-Glycoprotein Is Associated with Doxorubicin Chemoresistance in the Metastatic 4T1 Breast Cancer Model

Lili Bao, Aliyya Haque, Kamilah Jackson, Sidhartha Hazari, Krzysztof Moroz, Rachna Jetly, Srikanta Dash

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 4.39 MB

english, 2011

32

Attenuation of the Lysosomal Death Pathway by Lysosomal Cholesterol Accumulation

Hanna Appelqvist, Cathrine Nilsson, Brett Garner, Andrew J. Brown, Katarina Kågedal, Karin Öllinger

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 2.30 MB

english, 2011

33

Mesangial Cell Integrin αvβ8 Provides Glomerular Endothelial Cell Cytoprotection by Sequestering TGF-β and Regulating PECAM-1

Shenaz Khan, Sujata Lakhe-Reddy, Joseph H. McCarty, Christine M. Sorenson, Nader Sheibani, Louis F. Reichardt, Jane H. Kim, Bingcheng Wang, John R. Sedor, Jeffrey R. Schelling

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 2.22 MB

english, 2011

34

Obliterative Airway Remodeling: Molecular Evidence for Shared Pathways in Transplanted and Native Lungs

Danny Jonigk, Marlene Merk, Kais Hussein, Lavinia Maegel, Katharina Theophile, Michaela Muth, Ulrich Lehmann, Clemens L. Bockmeyer, Michael Mengel, Jens Gottlieb, Tobias Welte, Axel Haverich, Heiko Go

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 3.33 MB

english, 2011

35

Deregulation of E2-EPF Ubiquitin Carrier Protein in Papillary Renal Cell Carcinoma

Frederik C. Roos, Andrew J. Evans, Walburgis Brenner, Bill Wondergem, Jeffery Klomp, Pardeep Heir, Olga Roche, Christian Thomas, Heiko Schimmel, Kyle A. Furge, Bin T. Teh, Joachim W. Thüroff, Christia

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 1.17 MB

english, 2011

36

Accelerated Human Mutant Tau Aggregation by Knocking Out Murine Tau in a Transgenic Mouse Model

Kunie Ando, Karelle Leroy, Céline Héraud, Zehra Yilmaz, Michèle Authelet, Valèrie Suain, Robert De Decker, Jean-Pierre Brion

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 2.59 MB

english, 2011

37

Inhibition of Activin Receptor Type IIB Increases Strength and Lifespan in Myotubularin-Deficient Mice

Michael W. Lawlor, Benjamin P. Read, Rachel Edelstein, Nicole Yang, Christopher R. Pierson, Matthew J. Stein, Ariana Wermer-Colan, Anna Buj-Bello, Jennifer L. Lachey, Jasbir S. Seehra, Alan H. Beggs

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 2.32 MB

english, 2011

38

Suppression of Prostate Cancer Cell Rolling and Adhesion to Endothelium by 1α,25-Dihydroxyvitamin D3

Jong-Wei Hsu, Sayeda Yasmin-Karim, Michael R. King, Joel C. Wojciechowski, Deanne Mickelsen, Martha L. Blair, Huei-Ju Ting, Wen-Lung Ma, Yi-Fen Lee

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 1.38 MB

english, 2011

39

Ophthalmic Pterygium: A Stem Cell Disorder with Premalignant Features

Jeanie Chui, Minas T. Coroneo, Lien T. Tat, Roger Crouch, Denis Wakefield, Nick Di Girolamo

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 5.01 MB

english, 2011

40

TGF-β Sequestration by Mesangial Cell Integrin αvβ8: A Novel Mechanism of Glomerular Endothelial Cell Regulation

Ambra Pozzi, Roy Zent

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 536 KB

english, 2011

41

Syntenic Relationships between Genomic Profiles of Fiber-Induced Murine and Human Malignant Mesothelioma

Didier Jean, Emilie Thomas, Elodie Manié, Annie Renier, Aurélien de Reynies, Céline Lecomte, Pascal Andujar, Jocelyne Fleury-Feith, Françoise Galateau-Sallé, Marco Giovannini, Jessica Zucman-Rossi, Ma

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 1.75 MB

english, 2011

42

Gene Expression Patterns Related to Vascular Invasion and Aggressive Features in Endometrial Cancer

Monica Mannelqvist, Ingunn M. Stefansson, Geir Bredholt, Trond Hellem Bø, Anne M. Øyan, Inge Jonassen, Karl-Henning Kalland, Helga B. Salvesen, Lars A. Akslen

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 2.02 MB

english, 2011

43

The Development of Cutaneous Neurofibromas

Eeva-Mari Jouhilahti, Sirkku Peltonen, Tom Callens, Elina Jokinen, Anthony M. Heape, Ludwine Messiaen, Juha Peltonen

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 1.68 MB

english, 2011

44

Identification of a Mechanism Underlying Regulation of the Anti-Angiogenic Forkhead Transcription Factor FoxO1 in Cultured Endothelial Cells and Ischemic Muscle

Malgorzata Milkiewicz, Emilie Roudier, Jennifer L. Doyle, Anastassia Trifonova, Olivier Birot, Tara L. Haas

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 2.06 MB

english, 2011

45

IL-21 and IL-21 Receptor Expression in Lymphocytes and Neurons in Multiple Sclerosis Brain

John S. Tzartos, Matthew J. Craner, Manuel A. Friese, Karen B. Jakobsen, Jia Newcombe, Margaret M. Esiri, Lars Fugger

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 3.27 MB

english, 2011

46

Phosphoproteomic Analysis of Signaling Pathways in Head and Neck Squamous Cell Carcinoma Patient Samples

Mitchell J. Frederick, Amy J. VanMeter, Mayur A. Gadhikar, Ying C. Henderson, Hui Yao, Curtis C. Pickering, Michelle D. Williams, Adel K. El-Naggar, Vlad Sandulache, Emily Tarco, Jeffrey N. Myers, Gar

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 7.10 MB

english, 2011

47

Family Portrait: Renal Progenitor of Bowman's Capsule and Its Tubular Brothers

Paola Romagnani

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 701 KB

english, 2011

48

This Month in AJP

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 70 KB

english, 2011

49

Editorial Board

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 55 KB

english, 2011

50

Table of Contents

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 79 KB

english, 2011

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