Volume 45; Issue 2

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The Journal of Antibiotics
Volume 45; Issue 2

The Journal of Antibiotics

Volume 45; Issue 2

1

A new series of natural antifungals that inhibit P450 lanosterol C-14 demethylase. I. Taxonomy, fermentation, isolation and structural elucidation.

MATSUKUMA, SHOKO, OHTSUKA, TATSUO, KOTAKI, HIROMICHI, SHIRAI, HARUYOSHI, SANO, TAKASHI, WATANABE, KIMIHIRO, NAKAYAMA, NOBORU, ITEZONO, YOSHIKO, FUJIU, MORIO, SHIMMA, NOBUO, YOKOSE, KAZUTERU, OKUDA, TO

Journal:

The Journal of Antibiotics

Year:

1992

Language:

english

File:

PDF, 555 KB

english, 1992

2

44-Homooligomycins A and B, new antitumor antibiotics from Streptomyces bottropensis. Producing organism, fermentation, isolation, structure elucidation and biological properties.

YAMAZAKI, MASANORI, YAMASHITA, TAKUMI, HARADA, TAKASHI, NISHIKIORI, TAKAAKI, SAITO, SEIICHI, SHIMADA, NOBUYOSHI, FUJII, AKIO

Journal:

The Journal of Antibiotics

Year:

1992

Language:

english

File:

PDF, 434 KB

english, 1992

3

A new inhibitor of protein kinase C, RK-1409 (7-oxostaurosporine). I. Taxonomy and biological activity.

OSADA, HIROYUKI, KOSHINO, HIROYUKI, KUDO, TAKUJI, ONOSE, RIE, ISONO, KIYOSHI

Journal:

The Journal of Antibiotics

Year:

1992

Language:

english

File:

PDF, 337 KB

english, 1992

4

A new inhibitor of protein kinase C, RK-1409 (7-oxostaurosporine). II. Fermentation, isolation, physico-chemical properties and structure.

KOSHINO, HIROYUKI, OSADA, HIROYUKI, ISONO, KIYOSHI

Journal:

The Journal of Antibiotics

Year:

1992

Language:

english

File:

PDF, 216 KB

english, 1992

5

Metabolic products of microorganisms. 263 Nikkomycins Sz, Sx, Soz and Sox, new intermediates associated to the nikkomycin biosynthesis of Streptomyces tendae.

SCHÜZ, TRAUGOTT C., FIEDLER, HANS-PETER, ZÄHNER, HANS, RIECK, MATTHIAS, KÖNIG, WILFRIED A.

Journal:

The Journal of Antibiotics

Year:

1992

Language:

english

File:

PDF, 361 KB

english, 1992

6

New cholesterol biosynthesis inhibitors MC-031 (O-demethylchlorothricin), -032 (O-demethylhydroxychlorothricin), -033 and -034.

KAWASHIMA, AKIRA, NAKAMURA, YOSHIKUNI, OHTA, YOSHIE, AKAMA, TOMOKO, YAMAGISHI, MICHIO, HANADA, KAZUNORI

Journal:

The Journal of Antibiotics

Year:

1992

Language:

english

File:

PDF, 323 KB

english, 1992

7

N-Acyl 3-alkylidenyl- and 3-alkyl azetidin-2-ones: A new class of monocyclic .BETA.-lactam antibacterial agents. 1. Structure-activity relationships of 3-isopropylidene and 3-isopropyl analogs.

BRICKNER, STEVEN J., GAIKEMA, JEFFREY J., ZURENKO, GARY E., GREENFIELD, LAURA J., MANNINEN, PETER R., ULANOWICZ, DEBRA A.

Journal:

The Journal of Antibiotics

Year:

1992

Language:

english

File:

PDF, 676 KB

english, 1992

8

Transformation of streptonigrin into streptonigrone; synthesis and biological evaluation of antibiotics streptonigrin and streptonigrone alkyl ethers.

PREOBRAZHENSKAYA, M. N., HOLPNE-KOZLOVA, N. V., LAZHKO, E. I.

Journal:

The Journal of Antibiotics

Year:

1992

Language:

english

File:

PDF, 438 KB

english, 1992

9

Four diastereoisomers of cyclo(-Asp-Val-): inconsistency of their properties with the proposed structure of cairomycin A.

UEDA, TOSHIHISA, KIYOHARA, KUMIKO, LEE, SANNAMU, AOYAGI, HARUHIKO, IZUMIYA, NOBUO

Journal:

The Journal of Antibiotics

Year:

1992

Language:

english

File:

PDF, 247 KB

english, 1992

10

The synthesis, antibacterial, and .BETA.-lactamase inhibitory activity of a novel asparenomycin analog.

BOUTHILLIER, GILLES, MASTALERZ, HAROLD, MENARD, MARCEL, FUNG-TOMC, JOAN, GRADELSKI, ELIZABETH

Journal:

The Journal of Antibiotics

Year:

1992

Language:

english

File:

PDF, 398 KB

english, 1992

11

Effects of tautomycin, a protein phosphatase inhibitor, on recycling of mammalian cell surface molecules.

KURISAKI, TOMOHIRO, MAGAE, JUNJI, ISONO, KIYOSHI, NAGAI, KAZUO, YAMASAKI, MAKARI

Journal:

The Journal of Antibiotics

Year:

1992

Language:

english

File:

PDF, 361 KB

english, 1992

12

A seventeen kilodaltons peptidyl-prolyl cis-trans isomerase of the cyclosporin-producer Tolypocladium inflatum is sensitive to cyclosporin A.

ZOCHER, RAINER, KELLER, ULLRICH, LEE, CHAN, HOFFMANN, KAI

Journal:

The Journal of Antibiotics

Year:

1992

Language:

english

File:

PDF, 303 KB

english, 1992

13

A new indolocarbazole antibiotic, RK-286D.

OSADA, HIROYUKI, SATAKE, MASAYUKI, KOSHINO, HIROYUKI, ONOSE, RIE, ISONO, KIYOSHI

Journal:

The Journal of Antibiotics

Year:

1992

Language:

english

File:

PDF, 129 KB

english, 1992

14

Inhibition of herpes simplex virus type 1 DNA polymerase by the natural product oosporein.

TERRY, BRIAN J., LIU, WEN-CHIH, CIANCI, CHRISTOPHER W., PROSZYNSKI, ELIZABETH, FERNANDES, PRABHAVATHI, BUSH, KAREN, MEYERS, EDWARD

Journal:

The Journal of Antibiotics

Year:

1992

Language:

english

File:

PDF, 225 KB

english, 1992

15

Characterization of sannamycin A-nonproducing mutants of streptomyces sannanensis.

OHTA, TOSHIO, HASHIMOTO, ERI, HASEGAWA, MAMORU

Journal:

The Journal of Antibiotics

Year:

1992

Language:

english

File:

PDF, 173 KB

english, 1992

16

Novel antibiotics, cochleamycins A and B.

SHINDO, KAZUTOSHI, KAWAI, HIROYUKI

Journal:

The Journal of Antibiotics

Year:

1992

Language:

english

File:

PDF, 167 KB

english, 1992

17

Quartromicin, a complex of novel antiviral antibiotics. I. Production, isolation, physico-chemical properties and antiviral activity.

TSUNAKAWA, MITSUAKI, TENMYO, OSAMU, TOMITA, KOJI, NARUSE, NOBUAKI, KOTAKE, CHIKAKO, MIYAKI, TAKEO, KONISHI, MASATAKA, OKI, TOSHIKAZU

Journal:

The Journal of Antibiotics

Year:

1992

Language:

english

File:

PDF, 507 KB

english, 1992

18

Inhibition of tyrosine kinase and src oncogene functions by stable erbstatin analogues.

HORI, TAKASHI, KONDO, TETSURO, TSUJI, TOMOKO, IMOTO, MASAYA, UMEZAWA, KAZUO

Journal:

The Journal of Antibiotics

Year:

1992

Language:

english

File:

PDF, 152 KB

english, 1992

19

Nannochelins A, B and C, new iron-chelating compounds from Nannocystis exedens (myxobacteria). Production, isolation,physico-chemical and biological properties.

KUNZE, BRIGITTE, TROWITZSCH-KIENAST, WOLFRAM, HÖFLE, GERHARD, REICHENBACH, HANS

Journal:

The Journal of Antibiotics

Year:

1992

Language:

english

File:

PDF, 212 KB

english, 1992

20

A new series of natural antifungals that inhibit P450 lanosterol C-14 demethylase. II. mode of Action.

AOKI, YUHKO, YAMAZAKI, TOSHIKAZU, KONDOH, MASUMI, SUDOH, YURI, NAKAYAMA, NOBORU, SEKINE, YUZURU, SHIMADA, HISAO, ARISAWA, MIKIO

Journal:

The Journal of Antibiotics

Year:

1992

Language:

english

File:

PDF, 553 KB

english, 1992

21

Respiratory burst induced by phorbol ester in the presence of tautomycin, a novel inhibitor of protein phosphatases.

MAGAE, JUNJI, HINO, AYAKO, ISONO, KIYOSHI, NAGAI, KAZUO

Journal:

The Journal of Antibiotics

Year:

1992

Language:

english

File:

PDF, 300 KB

english, 1992

22

Protective effects of immunoactive peptide, FK565 against systemic and local infections with herpes simplex virus and murine cytomegalovirus and respiratory tract infection with influenza virus in mice.

YOKOTA, YOSHIKO, WATANABE, YUJI, WAKAI, YOSHIMI, MINE, YASUHIRO

Journal:

The Journal of Antibiotics

Year:

1992

Language:

english

File:

PDF, 450 KB

english, 1992

23

Characterization of an inducible transport system for glycerol in Streptomyces clavuligerus. Repression by L-serine.

MIÑAMBRES, BALTASAR, REGLERO, ANGEL, LUENGO, JOSÉ M.

Journal:

The Journal of Antibiotics

Year:

1992

Language:

english

File:

PDF, 616 KB

english, 1992

24

Synergism between 5-fluorouracil and oxanosine in inhibiting growth of ras-expressed cells in vitro and in vivo.

TSUCHIYA, KAYOKO S., MORIYA, YUKARI, HORI, MAKOTO, ITOH, OSAMU, TAKEUCHI, TOMIO, EKIMOTO, HISAO, HIRATSUKA, MASAHARU

Journal:

The Journal of Antibiotics

Year:

1992

Language:

english

File:

PDF, 154 KB

english, 1992

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