Volume 26; Issue 4

Main
Toxicologic Pathology
Volume 26; Issue 4

Toxicologic Pathology

Volume 26; Issue 4

1

The National Toxicology Program Evaluation of Genetically Altered Mice as Predictive Models for Identifying Carcinogens

Eastin, W. C., Haseman, J. K., Mahler, J. F., Bucher, J. R.

Journal:

Toxicologic Pathology

Year:

1998

Language:

english

File:

PDF, 1.42 MB

english, 1998

2

Point Mutations of the c-H-ras Gene in Spontaneous Liver Tumors of Transgenic Mice Carrying the Human c-H-ras Gene

Hayashi, S.-m., Mori, I., Nonoyama, T., Mitsumori, K.

Journal:

Toxicologic Pathology

Year:

1998

Language:

english

File:

PDF, 858 KB

english, 1998

3

Cancer Hazard Identification: Toward Simplification and Interpretability

Journal:

Toxicologic Pathology

Year:

1998

Language:

english

File:

PDF, 344 KB

english, 1998

4

Altered Differentiation of Hepatocytes in a Transgenic Mouse Model of Hepatocarcinogenesis

Enomoto, A., Sandgren, E. P., Maronpot, R. R.

Journal:

Toxicologic Pathology

Year:

1998

Language:

english

File:

PDF, 2.39 MB

english, 1998

5

Pathological Features of Spontaneous and Induced Tumors in Transgenic Mice Carrying a Human Prototype c-Ha-ras Gene Used for Six-Month Carcinogenicity Studies

Mitsumori, K., Koizumi, H., Nomura, T., Yamamoto, S.

Journal:

Toxicologic Pathology

Year:

1998

Language:

english

File:

PDF, 2.53 MB

english, 1998

6

An Evaluation of the Hemizygous Transgenic Tg.AC Mouse for Carcinogenicity Testing of Pharmaceuticals. II. A Genotypic Marker that Predicts Tumorigenic Responsiveness

Thompson, K. L., Rosenzweig, B. A., Sistare, F. D.

Journal:

Toxicologic Pathology

Year:

1998

Language:

english

File:

PDF, 950 KB

english, 1998

7

The International Life Sciences Institute's Role in the Evaluation of Alternative Methodologies for the Assessment of Carcinogenic Risk

Journal:

Toxicologic Pathology

Year:

1998

Language:

english

File:

PDF, 331 KB

english, 1998

8

Phenobarbital Does Not Promote Hepatic Tumorigenesis in a Twenty-Six-Week Bioassay in p53 Heterozygous Mice

Sagartz, J. E., Curtiss, S. W., Bunch, R. T., Davila, J. C., Morris, D. L., Alden, C. L.

Journal:

Toxicologic Pathology

Year:

1998

Language:

english

File:

PDF, 1.24 MB

english, 1998

9

Carcinogenic Responses of Transgenic Heterozygous p53 Knockout Mice to Inhaled 239PuO2 or Metallic Beryllium

Finch, G. L., March, T. H., Hahn, F. E., Barr, E. B., Belinsky, S. A., Hoover, M. D., Lechner, J. E., Nikula, K. J., Hobbs, C. H.

Journal:

Toxicologic Pathology

Year:

1998

Language:

english

File:

PDF, 1.37 MB

english, 1998

10

Morphological Characterization of Spindle Cell Tumors Induced in Transgenic Tg.AC Mouse Skin

Asano, S., Trempus, C. S., Spalding, J. W., Tennant, R. W., Battalora, M. StJ.

Journal:

Toxicologic Pathology

Year:

1998

Language:

english

File:

PDF, 1.58 MB

english, 1998

11

An Evaluation of the Hemizygous Transgenic Tg.AC Mouse for Carcinogenicity Testing of Pharmaceuticals. I. Evidence for a Confounding Nonresponder Phenotype

Weaver, J. L., Contrera, J. F., Rosenzweig, B. A., Thompson, K. L., Faustino, P. J., Strong, J. M., Ellison, C. D., Anderson, L. W., Prasanna, H. R., Long-Bradley, P. E., Lin, K. K., Zhang, J., Sistar

Journal:

Toxicologic Pathology

Year:

1998

Language:

english

File:

PDF, 1.08 MB

english, 1998

12

Dermal Carcinogenicity in Transgenic Mice: Relative Responsiveness of Male and Female Hemizygous and Homozygous Tg.AC Mice to 12-O-Tetradecanoylphorbol 13-Acetate (TPA) and Benzene

Blanchard, K. T., Ball, D. J., Holden, H. E., Furst, S. M., Stoltz, J. H., Stoll, R. E.

Journal:

Toxicologic Pathology

Year:

1998

Language:

english

File:

PDF, 770 KB

english, 1998

13

Tripropylene Glycol Diacrylate but Not Ethyl Acrylate Induces Skin Tumors in a Twenty-Week Short-Term Tumorigenesis Study in Tg.AC (v-Ha-ras) Mice

Nylander-French, L. A., French, J. E.

Journal:

Toxicologic Pathology

Year:

1998

Language:

english

File:

PDF, 889 KB

english, 1998

14

TGF is Dispensable for Skin Tumorigenesis in Tg.AC Mice

Humble, M. C., Szczesniak, C. J., Luetteke, N. C., Spalding, J. W., Cannon, R. E., Hansen, L. A., Lee, D. C., Tennant, R. W.

Journal:

Toxicologic Pathology

Year:

1998

Language:

english

File:

PDF, 861 KB

english, 1998

15

Lifetime Mouse Cancer Tests-The End of an Era?

Journal:

Toxicologic Pathology

Year:

1998

Language:

english

File:

PDF, 207 KB

english, 1998

16

Erratum

Journal:

Toxicologic Pathology

Year:

1998

File:

PDF, 115 KB

1998

17

The Potential of Genetically Altered Mice as Animal Models for Carcinogen Identification

Maronpot, R. R.

Journal:

Toxicologic Pathology

Year:

1998

Language:

english

File:

PDF, 509 KB

english, 1998

18

Spontaneous and Chemically Induced Proliferative Lesions in Tg.AC Transgenic and p53-Heterozygous Mice

Mahler, J. F., Flagler, N. D., Malarkey, D. E., Mann, P. C., Haseman, J. K., Eastin, W.

Journal:

Toxicologic Pathology

Year:

1998

Language:

english

File:

PDF, 1.98 MB

english, 1998