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Volume 142; Issue 1
Main
Toxicological Sciences
Volume 142; Issue 1
Toxicological Sciences
Volume 142; Issue 1
1
Human Hepatocytes Support the Hypertrophic but not the Hyperplastic Response to the Murine Nongenotoxic Hepatocarcinogen Sodium Phenobarbital in an In Vivo Study Using a Chimeric Mouse with Humanized Liver
Yamada, T.
,
Okuda, Y.
,
Kushida, M.
,
Sumida, K.
,
Takeuchi, H.
,
Nagahori, H.
,
Fukuda, T.
,
Lake, B. G.
,
Cohen, S. M.
,
Kawamura, S.
Journal:
Toxicological Sciences
Year:
2014
Language:
english
File:
PDF, 9.71 MB
Your tags:
english, 2014
2
SLC19A1, SLC46A1 and SLCO1B1 Polymorphisms as Predictors of Methotrexate-Related Toxicity in Portuguese Rheumatoid Arthritis Patients
Lima, A.
,
Bernardes, M.
,
Azevedo, R.
,
Monteiro, J.
,
Sousa, H.
,
Medeiros, R.
,
Seabra, V.
Journal:
Toxicological Sciences
Year:
2014
Language:
english
File:
PDF, 2.14 MB
Your tags:
english, 2014
3
P450-Mediated O-Demethylated Metabolite Is Responsible for Rat Hepatobiliary Toxicity of Pyridyltriazine-Containing PI3K Inhibitors
Subramanian, R.
,
Aidasani, D.
,
Bailey, K.
,
Branstetter, D.
,
Everds, N.
,
Jiang, J.
,
Norman, M. H.
,
Primack, R.
,
Skiles, G. L.
,
Soto, I.
,
Stec, M. M.
,
Wagner, M.
,
Wu, T.
,
Zhu, X.
,
Lebrec, H.
Journal:
Toxicological Sciences
Year:
2014
Language:
english
File:
PDF, 6.74 MB
Your tags:
english, 2014
4
A Systematic Assessment of Mitochondrial Function Identified Novel Signatures for Drug-Induced Mitochondrial Disruption in Cells
Li, N.
,
Oquendo, E.
,
Capaldi, R. A.
,
Robinson, J. P.
,
He, Y. D.
,
Hamadeh, H. K.
,
Afshari, C. A.
,
Lightfoot-Dunn, R.
,
Narayanan, P. K.
Journal:
Toxicological Sciences
Year:
2014
Language:
english
File:
PDF, 2.46 MB
Your tags:
english, 2014
5
Melatonin Improves Mitochondrial Function by Promoting MT1/SIRT1/PGC-1 Alpha-Dependent Mitochondrial Biogenesis in Cadmium-Induced Hepatotoxicity In Vitro
Guo, P.
,
Pi, H.
,
Xu, S.
,
Zhang, L.
,
Li, Y.
,
Li, M.
,
Cao, Z.
,
Tian, L.
,
Xie, J.
,
Li, R.
,
He, M.
,
Lu, Y.
,
Liu, C.
,
Duan, W.
,
Yu, Z.
,
Zhou, Z.
Journal:
Toxicological Sciences
Year:
2014
Language:
english
File:
PDF, 8.42 MB
Your tags:
english, 2014
6
Normalization of Nano-Sized TiO2-Induced Clastogenicity, Genotoxicity and Mutagenicity by Chlorophyllin Administration in Mice Brain, Liver, and Bone Marrow Cells
A. El-Ghor, A.
,
Noshy, M. M.
,
Galal, A.
,
Mohamed, H. R. H.
Journal:
Toxicological Sciences
Year:
2014
Language:
english
File:
PDF, 5.17 MB
Your tags:
english, 2014
7
The Role of Autophagy in Usnic Acid-Induced Toxicity in Hepatic Cells
Chen, S.
,
Dobrovolsky, V. N.
,
Liu, F.
,
Wu, Y.
,
Zhang, Z.
,
Mei, N.
,
Guo, L.
Journal:
Toxicological Sciences
Year:
2014
Language:
english
File:
PDF, 1.13 MB
Your tags:
english, 2014
8
Stable Isotope Labeling Method for the Investigation of Protein Haptenation by Electrophilic Skin Sensitizers
Parkinson, E.
,
Boyd, P.
,
Aleksic, M.
,
Cubberley, R.
,
O'Connor, D.
,
Skipp, P.
Journal:
Toxicological Sciences
Year:
2014
Language:
english
File:
PDF, 502 KB
Your tags:
english, 2014
9
Autoantibodies Associated with Prenatal and Childhood Exposure to Environmental Chemicals in Faroese Children
Osuna, C. E.
,
Grandjean, P.
,
Weihe, P.
,
El-Fawal, H. A. N.
Journal:
Toxicological Sciences
Year:
2014
Language:
english
File:
PDF, 430 KB
Your tags:
english, 2014
10
Comparison of Anorectic and Emetic Potencies of Deoxynivalenol (Vomitoxin) to the Plant Metabolite Deoxynivalenol-3-Glucoside and Synthetic Deoxynivalenol Derivatives EN139528 and EN139544
Wu, W.
,
Zhou, H.-R.
,
Bursian, S. J.
,
Pan, X.
,
Link, J. E.
,
Berthiller, F.
,
Adam, G.
,
Krantis, A.
,
Durst, T.
,
Pestka, J. J.
Journal:
Toxicological Sciences
Year:
2014
Language:
english
File:
PDF, 6.51 MB
Your tags:
english, 2014
11
Homologous Recombination Repair Signaling in Chemical Carcinogenesis: Prolonged Particulate Hexavalent Chromium Exposure Suppresses the Rad51 Response in Human Lung Cells
Qin, Q.
,
Xie, H.
,
Wise, S. S.
,
Browning, C. L.
,
Thompson, K. N.
,
Holmes, A. L.
,
Wise, J. P.
Journal:
Toxicological Sciences
Year:
2014
Language:
english
File:
PDF, 2.58 MB
Your tags:
english, 2014
12
Increased Susceptibility to Methotrexate-Induced Toxicity in Nonalcoholic Steatohepatitis
Hardwick, R. N.
,
Clarke, J. D.
,
Lake, A. D.
,
Canet, M. J.
,
Anumol, T.
,
Street, S. M.
,
Merrell, M. D.
,
Goedken, M. J.
,
Snyder, S. A.
,
Cherrington, N. J.
Journal:
Toxicological Sciences
Year:
2014
Language:
english
File:
PDF, 18.56 MB
Your tags:
english, 2014
13
Characterization of Nuclear Receptor-Mediated Murine Hepatocarcinogenesis of the Herbicide Pronamide and Its Human Relevance
LeBaron, M. J.
,
Rasoulpour, R. J.
,
Gollapudi, B. B.
,
Sura, R.
,
Kan, H. L.
,
Schisler, M. R.
,
Pottenger, L. H.
,
Papineni, S.
,
Eisenbrandt, D. L.
Journal:
Toxicological Sciences
Year:
2014
Language:
english
File:
PDF, 2.43 MB
Your tags:
english, 2014
14
Arsenic Exposure Disrupts the Normal Function of the FA/BRCA Repair Pathway
Peremarti, J.
,
Ramos, F.
,
Marcos, R.
,
Hernandez, A.
Journal:
Toxicological Sciences
Year:
2014
Language:
english
File:
PDF, 4.92 MB
Your tags:
english, 2014
15
Incorporating Population Variability and Susceptible Subpopulations into Dosimetry for High-Throughput Toxicity Testing
Wetmore, B. A.
,
Allen, B.
,
Clewell, H. J.
,
Parker, T.
,
Wambaugh, J. F.
,
Almond, L. M.
,
Sochaski, M. A.
,
Thomas, R. S.
Journal:
Toxicological Sciences
Year:
2014
Language:
english
File:
PDF, 1.98 MB
Your tags:
english, 2014
16
Impairment of Glutamate Signaling in Mouse Central Nervous System Neurons In Vitro by Tri-Ortho-Cresyl Phosphate at Noncytotoxic Concentrations
Hausherr, V.
,
van Thriel, C.
,
Krug, A.
,
Leist, M.
,
Schobel, N.
Journal:
Toxicological Sciences
Year:
2014
Language:
english
File:
PDF, 3.14 MB
Your tags:
english, 2014
17
Novel Hg2+-Induced Nephropathy in Rats and Mice Lacking Mrp2: Evidence of Axial Heterogeneity in the Handling of Hg2+ Along the Proximal Tubule
Zalups, R. K.
,
Joshee, L.
,
Bridges, C. C.
Journal:
Toxicological Sciences
Year:
2014
Language:
english
File:
PDF, 10.09 MB
Your tags:
english, 2014
18
Altered Surfactant Homeostasis and Alveolar Epithelial Cell Stress in Amiodarone-Induced Lung Fibrosis
Mahavadi, P.
,
Henneke, I.
,
Ruppert, C.
,
Knudsen, L.
,
Venkatesan, S.
,
Liebisch, G.
,
Chambers, R. C.
,
Ochs, M.
,
Schmitz, G.
,
Vancheri, C.
,
Seeger, W.
,
Korfei, M.
,
Guenther, A.
Journal:
Toxicological Sciences
Year:
2014
Language:
english
File:
PDF, 23.84 MB
Your tags:
english, 2014
19
Tissue Sensitivity of the Rat Upper and Lower Extrapulmonary Airways to the Inhaled Electrophilic Air Pollutants Diacetyl and Acrolein
Cichocki, J. A.
,
Smith, G. J.
,
Morris, J. B.
Journal:
Toxicological Sciences
Year:
2014
Language:
english
File:
PDF, 2.93 MB
Your tags:
english, 2014
20
Contemporary Reviews in Toxicology
Johnson, J. A.
,
Miller, G. W.
Journal:
Toxicological Sciences
Year:
2014
Language:
english
File:
PDF, 120 KB
Your tags:
english, 2014
21
From the Editor's Desk
Journal:
Toxicological Sciences
Year:
2014
Language:
english
File:
PDF, 173 KB
Your tags:
english, 2014
22
AMP-Activated Protein Kinase Deficiency Rescues Paraquat-Induced Cardiac Contractile Dysfunction Through an Autophagy-Dependent Mechanism
Wang, Q.
,
Yang, L.
,
Hua, Y.
,
Nair, S.
,
Xu, X.
,
Ren, J.
Journal:
Toxicological Sciences
Year:
2014
Language:
english
File:
PDF, 12.98 MB
Your tags:
english, 2014
23
Cardiac Epithelial-Mesenchymal Transition Is Blocked by Monomethylarsonous Acid (III)
Huang, T.
,
Barnett, J. V.
,
Camenisch, T. D.
Journal:
Toxicological Sciences
Year:
2014
Language:
english
File:
PDF, 6.72 MB
Your tags:
english, 2014
24
Profiling Dose-Dependent Activation of p53-Mediated Signaling Pathways by Chemicals with Distinct Mechanisms of DNA Damage
Clewell, R. A.
,
Sun, B.
,
Adeleye, Y.
,
Carmichael, P.
,
Efremenko, A.
,
McMullen, P. D.
,
Pendse, S.
,
Trask, O. J.
,
White, A.
,
Andersen, M. E.
Journal:
Toxicological Sciences
Year:
2014
Language:
english
File:
PDF, 2.84 MB
Your tags:
english, 2014
25
Systems Level Metabolic Phenotype of Methotrexate Administration in the Context of Non-alcoholic Steatohepatitis in the Rat
Kyriakides, M.
,
Hardwick, R. N.
,
Jin, Z.
,
Goedken, M. J.
,
Holmes, E.
,
Cherrington, N. J.
,
Coen, M.
Journal:
Toxicological Sciences
Year:
2014
Language:
english
File:
PDF, 4.34 MB
Your tags:
english, 2014
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