Volume 290; Issue 2-3

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Toxicology
Volume 290; Issue 2-3

Toxicology

Volume 290; Issue 2-3

1

Corrigendum to “Perillyl alcohol protects against ethanol induced acute liver injury in Wistar rats by inhibiting oxidative stress, NFκ-B activation and proinflammatory cytokine production” [Toxicology 279 (2011) 108–114]

Abdul Quaiyoom Khan, Sana Nafees, Sarwat Sultana

Journal:

Year:

2011

Language:

english

File:

PDF, 63 KB

english, 2011

2

A single mid-gestation exposure to TCDD yields a postnatal autoimmune signature, differing by sex, in early geriatric C57BL/6 mice

A. Mustafa, S.D. Holladay, S. Witonsky, D.P. Sponenberg, E. Karpuzoglu, R.M. Gogal Jr.

Journal:

Year:

2011

Language:

english

File:

PDF, 988 KB

english, 2011

3

Toxicogenomic investigation on rat testicular toxicity elicited by 1,3-dinitrobenzene

Takuya Matsuyama, Noriyo Niino, Naoki Kiyosawa, Kiyonori Kai, Munehiro Teranishi, Atsushi Sanbuissho

Journal:

Year:

2011

Language:

english

File:

PDF, 647 KB

english, 2011

4

Corrigendum to “TCDD adsorbed on silica as a model for TCDD contaminated soils: Evidence for suppression of humoral immunity in mice” [Toxicology 282 (2011) 82–87]

Barbara L.F. Kaplan, Robert B. Crawford, Natalia Kovalova, Amaya Arencibia, Seong Su Kim, Thomas J. Pinnavaia, Stephen A. Boyd, Brian J. Teppen, Norbert E. Kaminski

Journal:

Year:

2011

Language:

english

File:

PDF, 75 KB

english, 2011

5

Modulation of the expression of ABC transporters in murine (J774) macrophages exposed to large concentrations of the fluoroquinolone antibiotic moxifloxacin

Coralie M. Vallet, Béatrice Marquez, Naïma Nhiri, Ahalieyah Anantharajah, Marie-Paule Mingeot-Leclercq, Paul M. Tulkens, Jean-Yves Lallemand, Eric Jacquet, Françoise Van Bambeke

Journal:

Year:

2011

Language:

english

File:

PDF, 579 KB

english, 2011

6

Multifunctional drugs as novel antidotes for organophosphates’ poisoning

Ben Avi Weissman, Lily Raveh

Journal:

Year:

2011

Language:

english

File:

PDF, 280 KB

english, 2011

7

Gene expression and phosphoprotein profile of certain key neuronal signaling proteins following soman intoxication

G. RamaRao, B.K. Bhattacharya, Subodh Kumar, C.K. Waghmare

Journal:

Year:

2011

Language:

english

File:

PDF, 478 KB

english, 2011

8

Dose-dependent behavioral disturbances after a single neonatal Bisphenol A dose

Henrik Viberg, Anders Fredriksson, Sonja Buratovic, Per Eriksson

Journal:

Year:

2011

Language:

english

File:

PDF, 705 KB

english, 2011

9

Aryl hydrocarbon receptor-mediated Cyp1a1 expression is modulated in a CLOCK-dependent circadian manner

Naomi Tanimura, Naoki Kusunose, Naoya Matsunaga, Satoru Koyanagi, Shigehiro Ohdo

Journal:

Year:

2011

Language:

english

File:

PDF, 277 KB

english, 2011

10

Effects of temperature on rate constants of inhibition of organophosphorus and carbamate compounds

Kasim Abass Askar, Caleb Kudi, John Moody

Journal:

Year:

2011

Language:

english

File:

PDF, 124 KB

english, 2011

11

Histochemical localization of acetylcholinesterase

Kasim Abass Askar, Caleb Kudi, John Moody

Journal:

Year:

2011

Language:

english

File:

PDF, 91 KB

english, 2011

12

Explant culture of gastrointestinal tissue: Developing a tool for toxicology

Kevin J. Randall, John Turton, John R. Foster, John Masters

Journal:

Year:

2011

Language:

english

File:

PDF, 101 KB

english, 2011

13

Prolonged exposure of mice to 2,4-dinitrochlorobenzene (DNCB) results in a Th1/Th17 cytokine fingerprint

Mark D. Hayes, Ian Kimber, Rebecca J. Dearman

Journal:

Year:

2011

Language:

english

File:

PDF, 60 KB

english, 2011

14

A genomic approach to overcoming temozolomide resistance in glioblastoma multiforme

Joshua L. Smalley, Sarah K. Smalley, Shu-Dong Zhang, Simon J. Morley, Timothy W. Gant

Journal:

Year:

2011

Language:

english

File:

PDF, 88 KB

english, 2011

15

Dio3 mRNA is translationally down-regulated with drug-induced liver damage

Kate M. Dudek, Emma L. Marczylo, Laura Suter-Dick, Anne E. Willis, Timothy W. Gant

Journal:

Year:

2011

Language:

english

File:

PDF, 129 KB

english, 2011

16

Measurement of the urinary biomarker KIM-1 identifies the potential for aminoglycoside-induced nephrotoxicity in premature neonates

D.J. Antoine, S. McWilliam, V. Sabbisetti, M. Turner, R. Smyth, M. Pirmohamed, J.V. Bonventre, B.K. Park

Journal:

Year:

2011

Language:

english

File:

PDF, 91 KB

english, 2011

17

Platelet toxicity induced by the BCL2-inhibitor ABT-263, a novel anti-cancer agent

Meike Vogler, Hassan A. Hamali, Edward T.W. Bampton, David Dinsdale, Xiao-Ming Sun, Martin J.S. Dyer, Alison H. Goodall, Gerald M. Cohen

Journal:

Year:

2011

Language:

english

File:

PDF, 92 KB

english, 2011

18

Deficiency of regulatory heme causes an early synaptic failure in cultured neurons

Tatyana Chernova, Joern R. Steinert, Paul Richards, Rajendra Mistry, R.A. John Challiss, Andrew G. Smith, Ian D. Forsythe

Journal:

Year:

2011

Language:

english

File:

PDF, 155 KB

english, 2011

19

Primordial germ cells differentiated from embryonic stem cells as a system for investigating transgenerational epigenetic toxicity in vitro

Emma L. Marczylo, Justyna Janus, Kate M. Dudek, Timothy W. Gant

Journal:

Year:

2011

Language:

english

File:

PDF, 182 KB

english, 2011

20

The effect of four non-genotoxic carcinogens and four non-carcinogens on NRK-52E cells using a transcriptomics approach

Kate M. Bloch, Andrew Evans, Joost van Delft, Edward A. Lock

Journal:

Year:

2011

Language:

english

File:

PDF, 119 KB

english, 2011

21

REMOVED: Molecular mechanisms involved in resistance of CLL cells towards ABT-737, a specific BCL-2 inhibitor

Xiao-Ming Sun, Martin J. Dyer, Gerald. M. Cohen

Journal:

Year:

2011

File:

PDF, 17 KB

2011

22

BDE-99 causes down regulation of BDNF and Bcl-2 in primary rat neuronal culture

Jordi Blanco, José L. Domingo, Domènec J. Sánchez

Journal:

Year:

2011

Language:

english

File:

PDF, 182 KB

english, 2011

23

Cross-species characterisation of intestinal drug transporters

Ciaran Fisher, Tanya Coleman, Nick Plant

Journal:

Year:

2011

Language:

english

File:

PDF, 132 KB

english, 2011

24

The role of homologous recombination in the cellular response to sulphur mustard

Paul A. Jowsey, Faith M. Williams, Peter G. Blain

Journal:

Year:

2011

Language:

english

File:

PDF, 60 KB

english, 2011

25

Development of human embryonic stem cell-derived hepatic cells for toxicology analysis

Kat Czysz, Stephen Minger, Nick Thomas, Pat Doherty

Journal:

Year:

2011

Language:

english

File:

PDF, 150 KB

english, 2011

26

Polyamine–anthracene conjugates show promise in delivery of cytotoxic agents to human solid tumour cells

Xue Xiao, Otto Phanstiel, Heather M. Wallace

Journal:

Year:

2011

Language:

english

File:

PDF, 151 KB

english, 2011

27

Genotoxicity of orthopaedic wear debris: A patient study

Martin Figgitt, Michael Parry, Angus Maclean, Ashley Blom, Gordon Bannister, Steve Eastaugh-Waring, Ian Learmonth, Wilson Li, Charles Case

Journal:

Year:

2011

Language:

english

File:

PDF, 61 KB

english, 2011

28

Genomic instability induced by orthopaedic wear debris in cultured human fibroblasts

Martin Figgitt, Roger Newson, Ian Leslie, John Fisher, Eileen Ingham, Charles Case

Journal:

Year:

2011

Language:

english

File:

PDF, 75 KB

english, 2011

29

Behavioural effects of low level exposure to organophosphate pesticides

Claire Y. Savy, Christopher M. Morris, Peter G. Blain, Sarah J. Judge

Journal:

Year:

2011

Language:

english

File:

PDF, 64 KB

english, 2011

30

Evaluation of urinary biomarkers to assess degeneration and necrosis of ascending loop of Henle (ALH) in the rat

A. Spencer, T. Elsom, T. Gury, A. Jarecki, J.-C. Gautier

Journal:

Year:

2011

Language:

english

File:

PDF, 64 KB

english, 2011

31

Translational profiling of multiple myeloma cell lines RPMI8226 and 8226/R5 to discover novel markers of disease and drug resistance

Lindsay A. Wilson, Laura C. Cobbold, Anne E. Willis

Journal:

Year:

2011

Language:

english

File:

PDF, 79 KB

english, 2011

32

An investigation into the mechanism of trichloroethylene neurotoxicity in relation to Parkinsonism

Paul C. Keane, Sarah J. Judge, Peter G. Blain, Christopher M. Morris

Journal:

Year:

2011

Language:

english

File:

PDF, 63 KB

english, 2011

33

REMOVED: A polymorphism in the 5′ untranslated region of ERCC5 determines effectiveness of platinum-based chemotherapeutics

Joanna Somers, Ian G. Cannell, Alexander A. Kondrashov, Laura C. Cobbold, Lucy Young, Lindsay Wilson, Emilie Horvilleur, John-Paul Kilday, Keith A. Spriggs, Richard Grundy, Martin Bushell, Anne E. Wil

Journal:

Year:

2011

Language:

english

File:

PDF, 36 KB

english, 2011

34

The chemopreventive properties of cruciferous vegetables: Is oxidative stress in cancer cell cytotoxicity induced by glucosinolate hydrolysis products?

Nurul Huda Abd Kadir, John T. Rossiter, Nigel J. Gooderham

Journal:

Year:

2011

Language:

english

File:

PDF, 151 KB

english, 2011

35

Release of soluble metal ions from copper based dental alloys measured by ICPMS

Grace A. Afolaranmi, Hassan Al-Mufti, M. Helen Grant

Journal:

Year:

2011

Language:

english

File:

PDF, 61 KB

english, 2011

36

Effect of ascorbic acid on the distribution of Cr(VI) and Co(II) in the blood and organs of rats

Grace A. Afolaranmi, M. Helen Grant

Journal:

Year:

2011

Language:

english

File:

PDF, 61 KB

english, 2011

37

The role of AKR1A1 in GHB biosynthesis and breakdown in HEPG2 cells

Samar Alzeer, Elizabeth M. Ellis

Journal:

Year:

2011

Language:

english

File:

PDF, 112 KB

english, 2011

38

The role of Bcl-2 family proteins in an in vitro model of stroke

Dalbir Dhiraj, Martin Bushell, Giovanna Mallucci

Journal:

Year:

2011

Language:

english

File:

PDF, 116 KB

english, 2011

39

Motor activity is a sensitive behavioural biomarker of low level exposure to the shellfish toxin, domoic acid, in male and female rats

Andrew W. Baron, Rachel Steeg, Christopher M. Morris, Peter G. Blain, Sarah J. Judge

Journal:

Year:

2011

Language:

english

File:

PDF, 65 KB

english, 2011

40

Molecular toxicology and signal transduction pathways: Why not monitor directly!?

Riet Hilhorst, Rene Houtman, Rob Ruijtenbeek, Piet Boender, Michael McMillian, Peter Lord

Journal:

Year:

2011

Language:

english

File:

PDF, 94 KB

english, 2011

41

Spermidine/spermine N1-acetyltransferase (SSAT) induction as a marker of response to therapy in prostate cancer

Jun Li, Heather M. Wallace

Journal:

Year:

2011

Language:

english

File:

PDF, 106 KB

english, 2011

42

Insulin-like growth factor binding protein-5 as a biomarker for the detection of early liver disease

Emma M. Large, Anne Pryde, John N. Plevris, David J. Flint, M. Helen Grant

Journal:

Year:

2011

Language:

english

File:

PDF, 76 KB

english, 2011

43

Acute depletion of the prion protein may abrogate Aβ oligomer toxicity

Helois E. Radford, Nick C. Verity, Maria Guerra Martin, Giovanna R. Mallucci

Journal:

Year:

2011

Language:

english

File:

PDF, 102 KB

english, 2011

44

Impairment of synaptic assembly in prion disease

Julie Moreno, Helois Radford, Nick Verity, Maria Guerra Martin, Paul Glynn, David Dinsdale, Joern Steinert, Ian Forsythe, Giovanna Mallucci

Journal:

Year:

2011

Language:

english

File:

PDF, 76 KB

english, 2011

45

Screening for DDIs in the prophylactic treatment of aminoglycoside induced nephrotoxicity with statins

Alison V.M. Rodrigues, B. Kevin Park, Daniel J. Antoine

Journal:

Year:

2011

Language:

english

File:

PDF, 109 KB

english, 2011

46

Nrf2-mediated induction of antioxidant response element-driven gene expression by flavonoids is dependent on their chemical structure

Han Xiao, John M. Hourihan, Laura J. Brown, Michael McMahon, Derek Stewart, John D. Hayes

Journal:

Year:

2011

Language:

english

File:

PDF, 111 KB

english, 2011

47

Development and optimisation of a suitable method to generate soluble recombinant high mobility group box 1 protein

Hannah L. Aucott, Daniel J. Antoine, Robert Gibson, Dominic P. Williams, Lu-Yun Lian, B. Kevin Park

Journal:

Year:

2011

Language:

english

File:

PDF, 80 KB

english, 2011

48

Transporter mediated uptake and efflux of antiretroviral drugs: Potential for drug–drug interactions

Zoe Riches, Gary A. Cameron, Gabrielle M. Hawksworth

Journal:

Year:

2011

Language:

english

File:

PDF, 102 KB

english, 2011

49

Transcriptional regulation of the rat Ntcp and Bsep by PXR and FXR in vivo

Muhammad Farooq, Richard J. Weaver, Colin J. Henderson, Gabrielle M. Hawksworth

Journal:

Year:

2011

Language:

english

File:

PDF, 74 KB

english, 2011

50

Differential sensitivity to toxicity of statins: A comparison of liver and muscle cell lines

Rowena H. Gee, Nick J. Plant, Jonathan D. Johnston, Kate E. Plant

Journal:

Year:

2011

Language:

english

File:

PDF, 87 KB

english, 2011

51

Tcap: A novel biomarker of troglitazone induced cardiotoxicity

Harsharon K. Bahia, Julie C. Holder, Timothy W. Gant

Journal:

Year:

2011

Language:

english

File:

PDF, 67 KB

english, 2011

52

Non-catalytic mechanisms involved in glutathione S-transferase Pi mediated cytoprotection

David J. McGarry, C. Roland Wolf, Colin J. Henderson

Journal:

Year:

2011

Language:

english

File:

PDF, 81 KB

english, 2011

53

Radiation-induced transgenerational alterations in MicroRNA expression

Ruth C. Barber, Yuri E. Dubrova, Timothy W. Gant

Journal:

Year:

2011

Language:

english

File:

PDF, 115 KB

english, 2011

54

A systems biology approach towards understanding nuclear receptor interactions: Implications at the endocrine–xenobiotic signalling interface

Alexey N. Kolodkin, Anna Phillips, Steve Hood, Frank J. Bruggeman, Hans V. Westerhoff, Nick Plant

Journal:

Year:

2011

Language:

english

File:

PDF, 84 KB

english, 2011

55

Design principles of nuclear receptor signalling: How complex networking improves signal transduction

Alexey N. Kolodkin, Frank J. Bruggeman, Nick Plant, Martijn J. Moné, Barbara M. Bakker, Moray J. Campbell, Johannes P.T.M. van Leeuwen, Carsten Carlberg, Jacky L. Snoep, Hans V. Westerhoff

Journal:

Year:

2011

Language:

english

File:

PDF, 108 KB

english, 2011

56

Regulation of nuclear import pathways by vitamin D signalling: Potential biological implications

Supaporn Yimthaing, Nick Plant, Kate Plant

Journal:

Year:

2011

Language:

english

File:

PDF, 74 KB

english, 2011

57

Establishment of an HLA-typed cohort to elucidate the cellular and chemical basis of drug hypersensitivity reactions

Catherine Bell, Klara Martinsson, Lee Faulkner, Ana Alfirevic, Neil French, Jonathan Tugwood, Ina Schuppe-Koistinen, Karin Cederbrant, Munir Pirmohamed, Dean Naisbitt, B. Kevin Park

Journal:

Year:

2011

Language:

english

File:

PDF, 107 KB

english, 2011

58

Relationship between cell toxicity and interleukin (IL) 8 production for chemical contact allergens

I. Kimber, C. Portsmouth, G. Maxwell, R Pendlington, R.J. Dearman

Journal:

Year:

2011

Language:

english

File:

PDF, 93 KB

english, 2011

59

Changes in the level of expression and frequency of B220 positive lymphocytes may discriminate more accurately between contact allergens and skin irritants

Rebecca J. Dearman, Ian Kimber, Anne Marie Api, Jon Lalko

Journal:

Year:

2011

Language:

english

File:

PDF, 105 KB

english, 2011

60

PPARα and PPARδ nuclear receptor regulation of body weight and hepatic steatosis

Wojciech Garbacz, Larry Higgins, Colin Palmer

Journal:

Year:

2011

Language:

english

File:

PDF, 94 KB

english, 2011

61

Culture of 3T3 fibroblasts in collagen gels in the presence of ACE inhibitors

Grahame A. Busby, Simon MacKay, Phil Riches, M. Helen Grant

Journal:

Year:

2011

Language:

english

File:

PDF, 130 KB

english, 2011

62

Validation of methods involving miRNA isolation, purification and quantification and the potential of miRNAs to be used as biomarkers of nephrotoxicity

Jack W. Sharkey, Daniel J. Antoine, B. Kevin Park

Journal:

Year:

2011

Language:

english

File:

PDF, 106 KB

english, 2011

63

Differential activation of the aryl hydrocarbon receptor and regulation of differentiation in the epidermal equivalent model

Alison R. Forrester, Penny E. Lovat, Mark Graham, Faith M. Williams, Nick J. Reynolds

Journal:

Year:

2011

Language:

english

File:

PDF, 70 KB

english, 2011

64

Analytical methodologies for determining the metabolism and disposition of PEGylated biopharmaceuticals

George T. Edge, Victoria L. Elliott, Neil R. Kitteringham, Marie Phelan, Lu-Yun Lian, Rob Webster, B. Kevin Park

Journal:

Year:

2011

Language:

english

File:

PDF, 84 KB

english, 2011

65

Assessing the cytotoxic profile of novel endoperoxide derivatives

James W. Firman, Marion MacFarlane, B. Kevin Park, Amy E. Mercer

Journal:

Year:

2011

Language:

english

File:

PDF, 65 KB

english, 2011

66

Urinary biomarkers of renal injury in the hexachloro-1:3-butadiene treated male Hanover Wistar rat; a dose-response study at low dose levels

Ines Pereira, Aubrey Swain, John Turton, Cheryl L. Scudamore, David Maguire, Rosemary Smyth, Sofia Freitas, Michael Munday, Clare Stamp, Mitul Gandhi, Surjit Sondh, Holly Ashall, Ian Francis, Jennifer

Journal:

Year:

2011

Language:

english

File:

PDF, 108 KB

english, 2011

67

Using miRNA ‘fingerprints’ to investigate androgen-mediated phenotypic change

Corrinne V. Segal, Christopher J. Powell, Nigel J. Gooderham

Journal:

Year:

2011

Language:

english

File:

PDF, 109 KB

english, 2011

68

The elucidation of the mechanisms of bleomycin-induced cytotoxicity in alveolar type II cells in vitro

Bhavana Jagota, Amy E. Mercer, B. Kevin Park

Journal:

Year:

2011

Language:

english

File:

PDF, 67 KB

english, 2011

69

The role of the transcription factor Nrf2 in lipid metabolism in the liver

Joanne Walsh, Neil R. Kitteringham, Jules L. Griffin, Christopher E.P. Goldring, Samantha Williams, Helen Powell, B. Kevin Park

Journal:

Year:

2011

Language:

english

File:

PDF, 91 KB

english, 2011

70

Exploiting Drosophila melanogaster in toxicological studies: Analysis of drug uptake and excretion

Emanuela Zaharieva, Kevin Chipman, Matthias Soller

Journal:

Year:

2011

Language:

english

File:

PDF, 77 KB

english, 2011

71

Doxorubicin synergises with a TRAIL-R1-specific ligand to selectively target TRAIL-resistant breast tumour cells for apoptosis

Shambhavi Naik, Davina Twiddy, Roshna Mistry, Jennifer M. Edwards, Gerald M. Cohen, Rosemary A. Walker, Marion MacFarlane

Journal:

Year:

2011

Language:

english

File:

PDF, 109 KB

english, 2011

72

In vitro assessment of the interactions between diclofenac and tolmetin acyl glucuronide drug metabolites and human serum albumin

Thomas G. Hammond, Sophie L. Regan, Xiaoli Meng, James L. Maggs, Rosalind E. Jenkins, J. Gerry Kenna, Jean G. Sathish, Dominic P. Williams, B. Kevin Park

Journal:

Year:

2011

Language:

english

File:

PDF, 97 KB

english, 2011

73

Dissecting the mechanism of DNA damage induced photoreceptor cell death

Izabel Villela, Barbara Heidenreich, Manraj Cheema, Tiziana di Martino, Leona D. Samson, Lisiane B. Meira

Journal:

Year:

2011

Language:

english

File:

PDF, 62 KB

english, 2011

74

Novel OCT1 and OCT2 genetic variations—Potential link to metformin associated vitamin B12 deficiency during diabetes

Lewis A. Green, Daniel J. Antoine, Tracy Mills, Glynis Nicholls, B. Kevin Park, Munir Pirmohamed

Journal:

Year:

2011

Language:

english

File:

PDF, 75 KB

english, 2011

75

Reproductive, neuro- and immuno-toxicity in an extended one generation toxicity test with lead acetate

David J. Esdaile, Raluca Kubaszky, Peter Maslej, Judit Hargitai, Thomas Hanley, Daniel Minnema, Jayne Wright, Lewis Richard

Journal:

Year:

2011

Language:

english

File:

PDF, 63 KB

english, 2011

76

A possible role for BCRP in steroid hormone metabolism in endocrine organs

Anita C.A. Dankers, Jorien W.H. Sanderink, Jeanne C.L.M. Pertijs, Fred C.G.J. Sweep, Frans G.M. Russel, Rosalinde Masereeuw

Journal:

Year:

2011

Language:

english

File:

PDF, 76 KB

english, 2011

77

Urine proteomic profiling for biomarkers of acetaminophen-induced acute liver injury in mice and humans

Rachel P.L. van Swelm, Coby M.M. Laarakkers, Rosalinde Masereeuw, Frans G.M. Russel

Journal:

Year:

2011

Language:

english

File:

PDF, 65 KB

english, 2011

78

Genistein induces breast cancer-associated aromatase and stimulates estrogen-dependent tumor cell growth in in vitro breast cancer model

Majorie B.M. van Duursen, Evelien E.J.W. Smeets, Sandra M. Nijmeijer, Paul Chr de Jong, Martin van den Berg

Journal:

Year:

2011

Language:

english

File:

PDF, 78 KB

english, 2011

79

MDMA (Ecstasy)-induced liver toxicity in a HepG2 and immune cell co-culture model

Irene Antolino-Lobo, Irene S. Ludwig, Wirginia Strach, Fiona M.J. Wijnolts, Jolanda A.M. van den Brink, Daniëlle A. Fiechter, Martin van den Berg, Jan Meulenbelt, Majorie van Duursen

Journal:

Year:

2011

Language:

english

File:

PDF, 65 KB

english, 2011

80

Ultrasonic vocalisations and position distributions in rat pups: Animal friendly markers to test developmental (neuro)toxicity

Didima M.G. de Groot, Roderick Slieker, Jasper Swierstra, Luke Blauw, Lianne Damsteegt, Linda vd Horst, Marlies Otto, Ronald Bulthuis, Herma vd Wiel, Carina Rubingh

Journal:

Year:

2011

Language:

english

File:

PDF, 78 KB

english, 2011

81

Integrative Wireless Monitoring for Animal Wellbeing In Safety Pharmacology Studies

Didima De Groot, Roderick Slieker, Pascalle Van Loo, Elwin Verheij, Helle Lorentsen, Fabien Masse, Frank Bouwens

Journal:

Year:

2011

Language:

english

File:

PDF, 63 KB

english, 2011

82

Matrix modulation of the bioactivation of estragole by different alkenylbenzenes-containing herbs and spices and physiologically-based biokinetic modeling of possible in vivo effects

W. Alhusainy, S. van den Berg, A. Campana, A. Paini, A. Spenkelink, A. Punt, G. Scholz, B. Schilter, T. Adams, P.J. van Bladeren, I.M.C.M. Rietjens

Journal:

Year:

2011

Language:

english

File:

PDF, 68 KB

english, 2011

83

Fetal Alcohol Syndrome (FAS): Animal Friendly Markers In A Rat Model With Ethanol

Roderick C. Slieker, Rianne Nederlof, Linda J.M.L. vd Horst, Marlies Otto, Ruud Woutersen, Didima M.G. de Groot

Journal:

Year:

2011

Language:

english

File:

PDF, 53 KB

english, 2011

84

Microcystin-LR induces cytoskeleton system reorganization through hyperphosphorylation of tau and HSP27 via PP2A inhibition and subsequent activation of the p38 MAPK signaling pathway in neuroendocrine (PC12) cells

Guanmin Meng, Yu Sun, Wenyu Fu, Zonglou Guo, Lihong Xu

Journal:

Year:

2011

Language:

english

File:

PDF, 1.57 MB

english, 2011

85

Nano-copper induces oxidative stress and apoptosis in kidney via both extrinsic and intrinsic pathways

Abhijit Sarkar, Joydeep Das, Prasenjit Manna, Parames C. Sil

Journal:

Year:

2011

Language:

english

File:

PDF, 1.36 MB

english, 2011

86

Mechanism of Alternariol monomethyl ether-induced mitochondrial apoptosis in human colon carcinoma cells

Fatma Bensassi, Cindy Gallerne, Ossama Sharaf el dein, Mohamed Rabeh Hajlaoui, Hassen Bacha, Christophe Lemaire

Journal:

Year:

2011

Language:

english

File:

PDF, 1.14 MB

english, 2011

87

Comprehensive toxicity study of safrole using a medium-term animal model with gpt delta rats

M. Jin, A. Kijima, Y. Suzuki, D. Hibi, T. Inoue, Y. Ishii, T. Nohmi, A. Nishikawa, K. Ogawa, T. Umemura

Journal:

Year:

2011

Language:

english

File:

PDF, 664 KB

english, 2011

88

Decrease in urinary creatinine in acute kidney injury influences diagnostic value of urinary biomarker-to-creatinine ratio in rats

Yutaka Tonomura, Takeki Uehara, Emi Yamamoto, Mikinori Torii, Mitsunobu Matsubara

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Year:

2011

Language:

english

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PDF, 730 KB

english, 2011

89

The genotoxic potential of methapyrilene using the alkaline Comet assay in vitro and in vivo

Catherine C. Priestley, Sophie Regan, B. Kevin Park, Dominic P. Williams

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Year:

2011

Language:

english

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PDF, 847 KB

english, 2011

90

P. Frank, M. Alice Ottoboni, ,The Dose makes the Poison. A Plain-Language Guide to Toxicology third ed. (2011) John Wiley & Sons Inc. 978-0-470-38112-0 Paperback, 262 pp., GBP 20, 50.

Journal:

Year:

2011

Language:

english

File:

PDF, 84 KB

english, 2011

91

2,3,7,8-Tetrachlorodibenzo-p-dioxin induced autophagy in a bovine kidney cell line

Filomena Fiorito, Roberto Ciarcia, Giovanna Elvira Granato, Gabriella Marfe, Valentina Iovane, Salvatore Florio, Luisa De Martino, Ugo Pagnini

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Year:

2011

Language:

english

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PDF, 1.66 MB

english, 2011

92

Neutrophil–cytokine interactions in a rat model of sulindac-induced idiosyncratic liver injury

Wei Zou, Robert A. Roth, Husam S. Younis, Ernst Malle, Patricia E. Ganey

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Year:

2011

Language:

english

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PDF, 832 KB

english, 2011

93

Induction of DNA damage in human urothelial cells by the brominated flame retardant 2,2-bis(bromomethyl)-1,3-propanediol: Role of oxidative stress

Weixi Kong, Robert K. Kuester, Alfred Gallegos, I. Glenn Sipes

Journal:

Year:

2011

Language:

english

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PDF, 610 KB

english, 2011

94

Deprenyl prevents MPP+-induced oxidative damage in PC12 cells by the upregulation of Nrf2-mediated NQO1 expression through the activation of PI3K/Akt and Erk

Haibing Xiao, Feng Lv, Wuping Xu, Linhong Zhang, Ping Jing, Xu Cao

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Year:

2011

Language:

english

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PDF, 1.04 MB

english, 2011

95

Prenatal exposure to di-n-butyl phthalate induces anorectal malformations in male rat offspring

Jun-Tao Jiang, Wen-Lan Sun, Yi-Feng Jing, Shi-Bo Liu, Zheng Ma, Yan Hong, Long Ma, Chao Qin, Qiang Liu, Harrison J. Stratton, Shu-Jie Xia

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Year:

2011

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english

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PDF, 680 KB

english, 2011

96

Ionic mechanisms underlying cardiac toxicity of the organochloride solvent trichloromethane

Yuan Zhou, Hui-Jun Wu, Yan-Hui Zhang, Hai-Ying Sun, Tak-Ming Wong, Gui-Rong Li

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Year:

2011

Language:

english

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PDF, 1.35 MB

english, 2011

97

BDE-99 deregulates BDNF, Bcl-2 and the mRNA expression of thyroid receptor isoforms in rat cerebellar granular neurons

Jordi Blanco, Miquel Mulero, Marta López, José L. Domingo, Domènec J. Sánchez

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Year:

2011

Language:

english

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PDF, 759 KB

english, 2011

98

MeCP2 controls the expression of RASAL1 in the hepatic fibrosis in rats

Hui Tao, Cheng Huang, Jing-Jing Yang, Tao-Tao Ma, Er-Bao Bian, Lei Zhang, Xiong-Wen Lv, Yong Jin, Jun Li

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Year:

2011

Language:

english

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english, 2011

99

4-Nonylphenol triggers apoptosis and affects 17-β-Estradiol receptors in calvarial osteoblasts

Maria Giovanna Sabbieti, Dimitrios Agas, Francesco Palermo, Gilberto Mosconi, Giorgio Santoni, Consuelo Amantini, Valerio Farfariello, Luigi Marchetti

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2011

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english

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PDF, 712 KB

english, 2011

100

S-Adenosylhomocysteine enhances DNA damage through increased β-amyloid formation and inhibition of the DNA-repair enzyme OGG1b in microglial BV-2 cells

Hung-Chi Lin, Tuzz-Ying Song, Miao-Lin Hu

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Year:

2011

Language:

english

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PDF, 706 KB

english, 2011

101

Maternal quercetin intake during pregnancy results in an adapted iron homeostasis at adulthood

Kimberly Vanhees, Roger W. Godschalk, Anneke Sanders, Sahar Barjesteh van Waalwijk van Doorn-Khosrovani, Frederik J. van Schooten

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Year:

2011

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english

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PDF, 315 KB

english, 2011

102

Editorial Board

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2011

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english

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PDF, 44 KB

english, 2011

103

Contents

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2011

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english

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PDF, 45 KB

english, 2011

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