Toxicology and Applied Pharmacology

1

Methylmercury-induced toxicity is mediated by enhanced intracellular calcium through activation of phosphatidylcholine-specific phospholipase C

Mi Sun Kang, Ju Yeon Jeong, Ji Heui Seo, Hyung Jun Jeon, Kwang Mook Jung, Mi-Reyoung Chin, Chang-Kiu Moon, Joseph V. Bonventre, Sung Yun Jung, Dae Kyong Kim

Journal:

Year:

2006

Language:

english

File:

PDF, 574 KB

english, 2006

2

Genetic damage caused by methyl–parathion in mouse spermatozoa is related to oxidative stress

B. Piña-Guzmán, M.J. Solís-Heredia, A.E. Rojas-García, M. Urióstegui-Acosta, B. Quintanilla-Vega

Journal:

Toxicology and Applied Pharmacology

Year:

2006

Language:

english

File:

PDF, 426 KB

english, 2006

3

Potentiation of lead-induced cell death in PC12 cells by glutamate: Protection by N-acetylcysteine amide (NACA), a novel thiol antioxidant

Suman Penugonda, Suneetha Mare, P. Lutz, William A. Banks, Nuran Ercal

Journal:

Toxicology and Applied Pharmacology

Year:

2006

Language:

english

File:

PDF, 404 KB

english, 2006

4

Metabolic basis of ethanol-induced cytotoxicity in recombinant HepG2 cells: Role of nonoxidative metabolism

Hai Wu, Ping Cai, Dahn L. Clemens, Thomas R. Jerrells, G.A. Shakeel Ansari, Bhupendra S. Kaphalia

Journal:

Toxicology and Applied Pharmacology

Year:

2006

Language:

english

File:

PDF, 729 KB

english, 2006

5

Protection against oxidant-induced apoptosis by mitochondrial thioredoxin in SH-SY5Y neuroblastoma cells

Yan Chen, Min Yu, Dean P. Jones, J. Timothy Greenamyre, Jiyang Cai

Journal:

Toxicology and Applied Pharmacology

Year:

2006

Language:

english

File:

PDF, 562 KB

english, 2006

6

In vitro effects of brominated flame retardants and metabolites on CYP17 catalytic activity: A novel mechanism of action?

Rocío F. Cantón, J. Thomas Sanderson, Sandra Nijmeijer, Åke Bergman, Robert J. Letcher, Martin van den Berg

Journal:

Toxicology and Applied Pharmacology

Year:

2006

Language:

english

File:

PDF, 280 KB

english, 2006

7

Baicalein inhibition of oxidative-stress-induced apoptosis via modulation of ERKs activation and induction of HO-1 gene expression in rat glioma cells C6

Yen-Chou Chen, Jyh-Ming Chow, Cheng-Wei Lin, Chin-Yen Wu, Shing-Chuan Shen

Journal:

Toxicology and Applied Pharmacology

Year:

2006

Language:

english

File:

PDF, 2.60 MB

english, 2006

8

Methyl-β-cyclodextrin enhances the susceptibility of human breast cancer cells to carboplatin and 5-fluorouracil: Involvement of Akt, NF-κB and Bcl-2

Ankur Kumar Upadhyay, Sandeep Singh, Rishi Raj Chhipa, Maleppillil Vavachan Vijayakumar, Amrendra Kumar Ajay, Manoj Kumar Bhat

Journal:

Toxicology and Applied Pharmacology

Year:

2006

Language:

english

File:

PDF, 657 KB

english, 2006

9

Autoimmune response in MRL+/+ mice following treatment with dichloroacetyl chloride or dichloroacetic anhydride

Ping Cai, Rolf König, M. Firoze Khan, Suimin Qiu, Bhupendra S. Kaphalia, G.A.S. Ansari

Journal:

Toxicology and Applied Pharmacology

Year:

2006

Language:

english

File:

PDF, 533 KB

english, 2006

10

Kinetics of 3-(4-methylbenzylidene)camphor in rats and humans after dermal application

Ute M.D. Schauer, Wolfgang Völkel, Alexander Heusener, Thomas Colnot, Thomas H. Broschard, Friedrich von Landenberg, Wolfgang Dekant

Journal:

Toxicology and Applied Pharmacology

Year:

2006

Language:

english

File:

PDF, 355 KB

english, 2006

11

Toxicokinetics and biotransformation of 3-(4-methylbenzylidene)camphor in rats after oral administration

Wolfgang Völkel, Thomas Colnot, Ute M.D. Schauer, Thomas H. Broschard, Wolfgang Dekant

Journal:

Toxicology and Applied Pharmacology

Year:

2006

Language:

english

File:

PDF, 446 KB

english, 2006

12

Role of oxidative stress in thuringiensin-induced pulmonary toxicity

San-Fu Tsai, Chi Yang, Bing-Lan Liu, Jenn-Sheng Hwang, Shu-Peng Ho

Journal:

Toxicology and Applied Pharmacology

Year:

2006

Language:

english

File:

PDF, 343 KB

english, 2006

13

Gender-specific induction of cytochrome P450s in nonylphenol-treated FVB/NJ mice

Juan P. Hernandez, Laura M. Chapman, Xiomara C. Kretschmer, William S. Baldwin

Journal:

Toxicology and Applied Pharmacology

Year:

2006

Language:

english

File:

PDF, 595 KB

english, 2006

14

Energy metabolism and biotransformation as endpoints to pre-screen hepatotoxicity using a liver spheroid model

Jinsheng Xu, Wendy M. Purcell

Journal:

Toxicology and Applied Pharmacology

Year:

2006

Language:

english

File:

PDF, 813 KB

english, 2006

15

Distribution and reuse of 76Se-selenosugar in selenium-deficient rats

Kazuo T. Suzuki, Layla Somekawa, Noriyuki Suzuki

Journal:

Toxicology and Applied Pharmacology

Year:

2006

Language:

english

File:

PDF, 386 KB

english, 2006

16

Nitric oxide donors prevent while the nitric oxide synthase inhibitor l-NAME increases arachidonic acid plus CYP2E1-dependent toxicity

Defeng Wu, Arthur Cederbaum

Journal:

Toxicology and Applied Pharmacology

Year:

2006

Language:

english

File:

PDF, 957 KB

english, 2006

17

St. John's wort attenuates irinotecan-induced diarrhea via down-regulation of intestinal pro-inflammatory cytokines and inhibition of intestinal epithelial apoptosis

Ze-Ping Hu, Xiao-Xia Yang, Sui Yung Chan, An-Long Xu, Wei Duan, Yi-Zhun Zhu, Fwu-Shan Sheu, Urs Alex Boelsterli, Eli Chan, Qiang Zhang, Jian-Cheng Wang, Pui Lai Rachel Ee, Hwee Ling Koh, Min Huang, Sh

Journal:

Toxicology and Applied Pharmacology

Year:

2006

Language:

english

File:

PDF, 1.02 MB

english, 2006

18

4-Hydroxynonenal induces mitochondrial oxidative stress, apoptosis and expression of glutathione S-transferase A4-4 and cytochrome P450 2E1 in PC12 cells

Haider Raza, Annie John

Journal:

Toxicology and Applied Pharmacology

Year:

2006

Language:

english

File:

PDF, 1007 KB

english, 2006

19

Changes in gene expression in human renal proximal tubule cells exposed to low concentrations of S-(1,2-dichlorovinyl)-l-cysteine, a metabolite of trichloroethylene

Edward A. Lock, Jeremy L. Barth, Scott W. Argraves, Rick G. Schnellmann

Journal:

Toxicology and Applied Pharmacology

Year:

2006

Language:

english

File:

PDF, 682 KB

english, 2006

20

The effects of combined exposure to the pyrethroids deltamethrin and S-bioallethrin on hippocampal inhibition and skeletal muscle hyperexcitability in rats

David E. Ray, Steven A. Burr, Timothy Lister

Journal:

Toxicology and Applied Pharmacology

Year:

2006

Language:

english

File:

PDF, 368 KB

english, 2006

21

Editorial Board

Journal:

Toxicology and Applied Pharmacology

Year:

2006

Language:

english

File:

PDF, 32 KB

english, 2006

22

Volume 216; Issue 2

Methylmercury-induced toxicity is mediated by enhanced intracellular calcium through activation of phosphatidylcholine-specific phospholipase C

Genetic damage caused by methyl–parathion in mouse spermatozoa is related to oxidative stress

Potentiation of lead-induced cell death in PC12 cells by glutamate: Protection by N-acetylcysteine amide (NACA), a novel thiol antioxidant

Metabolic basis of ethanol-induced cytotoxicity in recombinant HepG2 cells: Role of nonoxidative metabolism

Protection against oxidant-induced apoptosis by mitochondrial thioredoxin in SH-SY5Y neuroblastoma cells

In vitro effects of brominated flame retardants and metabolites on CYP17 catalytic activity: A novel mechanism of action?

Baicalein inhibition of oxidative-stress-induced apoptosis via modulation of ERKs activation and induction of HO-1 gene expression in rat glioma cells C6

Methyl-β-cyclodextrin enhances the susceptibility of human breast cancer cells to carboplatin and 5-fluorouracil: Involvement of Akt, NF-κB and Bcl-2

Autoimmune response in MRL+/+ mice following treatment with dichloroacetyl chloride or dichloroacetic anhydride

Kinetics of 3-(4-methylbenzylidene)camphor in rats and humans after dermal application

Toxicokinetics and biotransformation of 3-(4-methylbenzylidene)camphor in rats after oral administration

Role of oxidative stress in thuringiensin-induced pulmonary toxicity

Gender-specific induction of cytochrome P450s in nonylphenol-treated FVB/NJ mice

Energy metabolism and biotransformation as endpoints to pre-screen hepatotoxicity using a liver spheroid model

Distribution and reuse of 76Se-selenosugar in selenium-deficient rats

Nitric oxide donors prevent while the nitric oxide synthase inhibitor l-NAME increases arachidonic acid plus CYP2E1-dependent toxicity

St. John's wort attenuates irinotecan-induced diarrhea via down-regulation of intestinal pro-inflammatory cytokines and inhibition of intestinal epithelial apoptosis

4-Hydroxynonenal induces mitochondrial oxidative stress, apoptosis and expression of glutathione S-transferase A4-4 and cytochrome P450 2E1 in PC12 cells

Changes in gene expression in human renal proximal tubule cells exposed to low concentrations of S-(1,2-dichlorovinyl)-l-cysteine, a metabolite of trichloroethylene

The effects of combined exposure to the pyrethroids deltamethrin and S-bioallethrin on hippocampal inhibition and skeletal muscle hyperexcitability in rats

Editorial Board

Contents

Contents