Volume 274; Issue 1

Toxicology and Applied Pharmacology

Volume 274; Issue 1

1

Keap1 redox-dependent regulation of doxorubicin-induced oxidative stress response in cardiac myoblasts

Nordgren, Kendra K.S., Wallace, Kendall B.

Journal:

Toxicology and Applied Pharmacology

Year:

2014

Language:

english

File:

PDF, 2.48 MB

english, 2014

2

Cytotoxicity of synthetic cannabinoids on primary neuronal cells of the forebrain: the involvement of cannabinoid CB1 receptors and apoptotic cell death

Tomiyama, Ken-ichi, Funada, Masahiko

Journal:

Toxicology and Applied Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.62 MB

english, 2014

3

Short-term calorie restriction feminizes the mRNA profiles of drug metabolizing enzymes and transporters in livers of mice

Fu, Zidong Donna, Klaassen, Curtis D.

Journal:

Toxicology and Applied Pharmacology

Year:

2014

Language:

english

File:

PDF, 2.68 MB

english, 2014

4

Iron supplementation at high altitudes induces inflammation and oxidative injury to lung tissues in rats

Salama, Samir A., Omar, Hany A., Maghrabi, Ibrahim A., AlSaeed, Mohammed S., EL-Tarras, Adel E.

Journal:

Toxicology and Applied Pharmacology

Year:

2014

Language:

english

File:

PDF, 1018 KB

english, 2014

5

Analysis of changes in hepatic gene expression in a murine model of tolerance to acetaminophen hepatotoxicity (autoprotection)

O'Connor, Meeghan A., Koza-Taylor, Petra, Campion, Sarah N., Aleksunes, Lauren M., Gu, Xinsheng, Enayetallah, Ahmed E., Lawton, Michael P., Manautou, José E.

Journal:

Toxicology and Applied Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.80 MB

english, 2014

6

Hepatocyte-based in vitro model for assessment of drug-induced cholestasis

Chatterjee, Sagnik, Richert, Lysiane, Augustijns, Patrick, Annaert, Pieter

Journal:

Toxicology and Applied Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.31 MB

english, 2014

7

Natural indoles, indole-3-carbinol and 3,3′-diindolymethane, inhibit T cell activation by staphylococcal enterotoxin B through epigenetic regulation involving HDAC expression

Busbee, Philip B., Nagarkatti, Mitzi, Nagarkatti, Prakash S.

Journal:

Toxicology and Applied Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.76 MB

english, 2014

8

The induction of heme oxygenase-1 suppresses heat shock protein 90 and the proliferation of human breast cancer cells through its byproduct carbon monoxide

Lee, Wen-Ying, Chen, Yen-Chou, Shih, Chwen-Ming, Lin, Chun-Mao, Cheng, Chia-Hsiung, Chen, Ku-Chung, Lin, Cheng-Wei

Journal:

Toxicology and Applied Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.16 MB

english, 2014

9

Pre-treatment with cardamonin protects against cisplatin-induced nephrotoxicity in rats: Impact on NOX-1, inflammation and apoptosis

El-Naga, Reem N.

Journal:

Toxicology and Applied Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.68 MB

english, 2014

10

Urinary arsenic metabolism in a Western Chinese population exposed to high-dose inorganic arsenic in drinking water: Influence of ethnicity and genetic polymorphisms

Fu, Songbo, Wu, Jie, Li, Yuanyuan, Liu, Yan, Gao, Yanhui, Yao, Feifei, Qiu, Chuanying, Song, Li, Wu, Yu, Liao, Yongjian, Sun, Dianjun

Journal:

Toxicology and Applied Pharmacology

Year:

2014

Language:

english

File:

PDF, 283 KB

english, 2014

11

Intake of high-fat diet stimulates the risk of ultraviolet radiation-induced skin tumors and malignant progression of papillomas to carcinoma in SKH-1 hairless mice

Vaid, Mudit, Singh, Tripti, Prasad, Ram, Katiyar, Santosh K.

Journal:

Toxicology and Applied Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.25 MB

english, 2014

12

Combination of ascorbate/epigallocatechin-3-gallate/gemcitabine synergistically induces cell cycle deregulation and apoptosis in mesothelioma cells

Martinotti, Simona, Ranzato, Elia, Parodi, Monica, Vitale, Massimo, Burlando, Bruno

Journal:

Toxicology and Applied Pharmacology

Year:

2014

Language:

english

File:

PDF, 878 KB

english, 2014

13

Allosteric modulators of the hERG K+ channel

Yu, Zhiyi, Klaasse, Elisabeth, Heitman, Laura H., IJzerman, Adriaan P.

Journal:

Toxicology and Applied Pharmacology

Year:

2014

Language:

english

File:

PDF, 961 KB

english, 2014

14

CYP2E1-dependent and leptin-mediated hepatic CD57 expression on CD8+ T cells aid progression of environment-linked nonalcoholic steatohepatitis

Seth, Ratanesh Kumar, Das, Suvarthi, Kumar, Ashutosh, Chanda, Anindya, Kadiiska, Maria B., Michelotti, Gregory, Manautou, Jose, Diehl, Anna Mae, Chatterjee, Saurabh

Journal:

Toxicology and Applied Pharmacology

Year:

2014

Language:

english

File:

PDF, 2.50 MB

english, 2014

15

Case study on the utility of hepatic global gene expression profiling in the risk assessment of the carcinogen furan

Jackson, Anna Francina, Williams, Andrew, Recio, Leslie, Waters, Michael D., Lambert, Iain B., Yauk, Carole L.

Journal:

Toxicology and Applied Pharmacology

Year:

2014

Language:

english

File:

PDF, 2.04 MB

english, 2014

16

The contribution of heavy metals in cigarette smoke condensate to malignant transformation of breast epithelial cells and in vivo initiation of neoplasia through induction of a PI3K–AKT–NFκB cascade

Mohapatra, Purusottam, Preet, Ranjan, Das, Dipon, Satapathy, Shakti Ranjan, Siddharth, Sumit, Choudhuri, Tathagata, Wyatt, Michael D., Kundu, Chanakya Nath

Journal:

Toxicology and Applied Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.96 MB

english, 2014

17

Growth inhibitory effect of KYKZL-1 on Hep G2 cells via inhibition of AA metabolites and caspase-3 pathway and cell cycle arrest

Cheng, Jing, Du, Yi-Fang, Xiao, Zhi-Yi, Pan, Li-Li, Li, Wei, Huan, Lin, Gong, Zhu-Nan, Wei, Shao-Hua, Huang, Shi-Qian, Xun, Wei, Zhang, Yi, Chang, Lei-Lei, Xie, Meng-Yu, Ao, Gui-Zhen, Cai, Jie, Qiu, T

Journal:

Toxicology and Applied Pharmacology

Year:

2014

Language:

english

File:

PDF, 2.24 MB

english, 2014

18

Contents

Journal:

Toxicology and Applied Pharmacology

Year:

2014

Language:

english

File:

PDF, 42 KB

english, 2014

19

High-throughput identification of off-targets for the mechanistic study of severe adverse drug reactions induced by analgesics

Pan, Jian-Bo, Ji, Nan, Pan, Wen, Hong, Ru, Wang, Hao, Ji, Zhi-Liang

Journal:

Toxicology and Applied Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.13 MB

english, 2014

20

Bidirectional regulation of bakuchiol, an estrogenic-like compound, on catecholamine secretion

Mao, Haoping, Wang, Hong, Ma, Shangwei, Xu, Yantong, Zhang, Han, Wang, Yuefei, Niu, Zichang, Fan, Guanwei, Zhu, Yan, Gao, Xiu Mei

Journal:

Toxicology and Applied Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.55 MB

english, 2014

21

Editorial Board

Journal:

Toxicology and Applied Pharmacology

Year:

2014

Language:

english

File:

PDF, 34 KB

english, 2014

22

Contents Continued

Journal:

Toxicology and Applied Pharmacology

Year:

2014

Language:

english

File:

PDF, 34 KB

english, 2014