Volume 24; Issue 6

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Toxicology in Vitro
Volume 24; Issue 6

Toxicology in Vitro

Volume 24; Issue 6

1

Identifying and characterizing chemical skin sensitizers without animal testing: Colipa’s research and method development program

P. Aeby, T. Ashikaga, S. Bessou-Touya, A. Schepky, F. Gerberick, P. Kern, M. Marrec-Fairley, G. Maxwell, J.-M. Ovigne, H. Sakaguchi, K. Reisinger, M. Tailhardat, S. Martinozzi-Teissier, P. Winkler

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 578 KB

english, 2010

2

Inability to confirm estrogenicity of the heterocyclic amine PhIP in two in vitro assays

Richard M. Evans, Sinikka Rahte, Andreas Kortenkamp

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 337 KB

english, 2010

3

Partial characterization of the hemolytic activity of the nematocyst venom from the jellyfish Cyanea nozakii Kishinouye

Jinhua Feng, Huahua Yu, Ronge Xing, Song Liu, Lin Wang, Shengbao Cai, Pengcheng Li

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 597 KB

english, 2010

4

An evaluation of a cultured human corneal epithelial tissue model for the determination of the ocular irritation potential of pharmaceutical process materials

Christopher W. Seaman, Andrew Whittingham, Robert Guest, Neil Warren, Michael J. Olson, Frederick J. Guerriero, Els Adriaens, Bart De Wever

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 1.31 MB

english, 2010

5

Development of a new opacitometer for the bovine corneal opacity and permeability (BCOP) assay

Freddy Van Goethem, Erik Hansen, Marc Sysmans, Ann De Smedt, Philippe Vanparys, Jacky Van Gompel

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 716 KB

english, 2010

6

Gadolinium-promoted precipitation of calcium phosphate is associated with profibrotic activation of RAW 264.7 macrophages

Bao-Di Gou, Sha Bian, Tian-Lan Zhang, Kui Wang

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 1.34 MB

english, 2010

7

Association between diphenyl diselenide and cadmium chloride attenuates the toxicity of both in tissues of mice in vitro

Ricardo Brandão, Renata de Oliveira, Cristina W. Nogueira

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 554 KB

english, 2010

8

The sensitivity of the MDA-kb2 cell in vitro assay in detecting anti-androgenic chemicals – Identification of sources of variability and estimation of statistical power

Sibylle Ermler, Martin Scholze, Andreas Kortenkamp

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 737 KB

english, 2010

9

Identification of PDL-1 as a novel biomarker of sensitizer exposure in dendritic-like cells

Emma H. Williams, Charlotte A. Williams, Julie D. McLeod

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 3.25 MB

english, 2010

10

Passive diffusion of acetylcholinesterase oxime reactivators through the blood–brain barrier: Influence of molecular structure

Jana Zdarova Karasova, Miroslav Pohanka, Kamil Musilek, Filip Zemek, Kamil Kuca

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 2.47 MB

english, 2010

11

Finite element modelling and design of a concentration gradient generating bioreactor: Application to biological pattern formation and toxicology

Giovanni Vozzi, Daniele Mazzei, Annalisa Tirella, Federico Vozzi, Arti Ahluwalia

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 1.28 MB

english, 2010

12

Optimizing urothelial cell preparation for the human urinary micronucleus assay

F. Fortin, T. Anghel, P. Brochu, N. Lemieux

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 429 KB

english, 2010

13

Predicting skin sensitization potential and inter-laboratory reproducibility of a human Cell Line Activation Test (h-CLAT) in the European Cosmetics Association (COLIPA) ring trials

Hitoshi Sakaguchi, Cindy Ryan, Jean-Marc Ovigne, Klaus R. Schroeder, Takao Ashikaga

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 496 KB

english, 2010

14

Apoptosis-inducing action of two products from oxidation of sesamol, an antioxidative constituent of sesame oil: A possible cytotoxicity of oxidized antioxidant

Aya Fujimoto, Yoshimi Shingai, Toshihisa B. Oyama, Takuya Kawanai, Erika Hashimoto, Kazuki Koizumi, Kaori Kimura, Toshiya Masuda, Yasuo Oyama

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 954 KB

english, 2010

15

Prevention of tertiary butyl hydroperoxide induced oxidative impairment and cell death by a novel antioxidant protein molecule isolated from the herb, Phyllanthus niruri

Mrinal K. Sarkar, Parames C. Sil

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 827 KB

english, 2010

16

Midostaurin (PKC412) modulates differentiation and maturation of human myeloid dendritic cells

Yu-Chuen Huang, Hui-Ru Shieh, Yu-Jen Chen

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 742 KB

english, 2010

17

The Björn Ekwall Memorial Award

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 154 KB

english, 2010

18

Effects of acute ethanol treatment on NCCIT cells and NCCIT cell-derived embryoid bodies (EBs)

Kyoung Hwa Jung, Nando Dulal Das, Ji Hyun Park, Hyung Tae Lee, Mi Ran Choi, Mi Kyung Chung, Kyoung Sun Park, Myung Hun Jung, Boung Chul Lee, Ihn Geun Choi, Young Gyu Chai

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 1.09 MB

english, 2010

19

Microcystin-LR activates the ERK1/2 kinases and stimulates the proliferation of the monkey kidney-derived cell line Vero-E6

E. Dias, P. Matos, P. Pereira, M.C.C. Batoréu, M.J. Silva, P. Jordan

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 578 KB

english, 2010

20

NGF induced differentiated PC12 cells as in vitro tool to study 4-hydroxynonenal induced cellular damage

M.A. Siddiqui, M.P. Kashyap, V.K. Khanna, S. Yadav, A.B. Pant

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 1.22 MB

english, 2010

21

Effects of sub-toxic Cadmium concentrations on bone gene expression program: Results of an in vitro study

Maria Bodo, Stefania Balloni, Eleonora Lumare, Mauro Bacci, Mario Calvitti, Marco Dell’Omo, Nicola Murgia, Lorella Marinucci

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 1.84 MB

english, 2010

22

Isorhamnetin-3-glucoside alleviates oxidative stress and opacification in selenite cataract in vitro

V. Gayathri Devi, B.N. Rooban, V. Sasikala, V. Sahasranamam, Annie Abraham

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 749 KB

english, 2010

23

In vitro and in vivo anti-angiogenesis effect of shallot (Allium ascalonicum): A heat-stable and flavonoid-rich fraction of shallot extract potently inhibits angiogenesis

Parivash Seyfi, Ali Mostafaie, Kamran Mansouri, Delnia Arshadi, Hamid-Reza Mohammadi-Motlagh, Amir Kiani

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 670 KB

english, 2010

24

Fucoxanthin induces apoptosis in human leukemia HL-60 cells through a ROS-mediated Bcl-xL pathway

Kil-Nam Kim, Soo-Jin Heo, Sung-Myung Kang, Ginnae Ahn, You-Jin Jeon

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 864 KB

english, 2010

25

Use of IL-8 release and p38 MAPK activation in THP-1 cells to identify allergens and to assess their potency in vitro

M. Mitjans, V. Galbiati, L. Lucchi, B. Viviani, M. Marinovich, C.L. Galli, E. Corsini

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 645 KB

english, 2010

26

Enzyme activity inhibition and secondary structure disruption of nano-TiO2 on pepsin

Rong-Rong Zhu, Wen-Rui Wang, Xiao-Yu Sun, Hui Liu, Shi-Long Wang

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 1.27 MB

english, 2010

27

Cellular responses by stable and uniform ultrafine titanium dioxide particles in culture-medium dispersions when secondary particle size was 100 nm or less

Masanori Horie, Keiko Nishio, Katsuhide Fujita, Haruhisa Kato, Shigehisa Endoh, Mie Suzuki, Ayako Nakamura, Arisa Miyauchi, Shinichi Kinugasa, Kazuhiro Yamamoto, Hitoshi Iwahashi, Hideki Murayama, Ets

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 1.01 MB

english, 2010

28

AhR-agonistic, anti-androgenic, and anti-estrogenic potencies of 2-isopropylthioxanthone (ITX) as determined by in vitro bioassays and gene expression profiling

Ad Peijnenburg, Jenneke Riethof-Poortman, Hakan Baykus, Liza Portier, Toine Bovee, Ron Hoogenboom

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 561 KB

english, 2010

29

Cytotoxicity of atorvastatin and simvastatin on primary rainbow trout (Oncorhynchus mykiss) hepatocytes

Kathrin Sabine Ellesat, Knut-Erik Tollefsen, Anders Åsberg, Kevin V. Thomas, Ketil Hylland

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 1.12 MB

english, 2010

30

Activation of caspases and poly (ADP-ribose) polymerase cleavage to induce apoptosis in leukemia HL-60 cells by Inula racemosa

Harish Chandra Pal, Irum Sehar, Shashi Bhushan, Bishan Dutt Gupta, Ajit Kumar Saxena

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 1.42 MB

english, 2010

31

Protective potential of trans-resveratrol against 4-hydroxynonenal induced damage in PC12 cells

M.A. Siddiqui, M.P. Kashyap, V. Kumar, A.A. Al-Khedhairy, J. Musarrat, A.B. Pant

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 580 KB

english, 2010

32

Enhanced toxicity and ROS generation by doxorubicin in primary cultures of cardiomyocytes from neonatal metallothionein-I/II null mice

Ze Fu, Jiabin Guo, Li Jing, Ruisheng Li, Tingfen Zhang, Shuangqing Peng

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 829 KB

english, 2010

33

The roles of the thioredoxin system and peroxiredoxins in 1-methyl-4-phenyl-pyridinium ion-induced cytotoxicity in rat pheochromocytoma cells

Victor T.K. Chen, Chuen-Lin Huang, Yi-Chao Lee, Wei-Chen Liao, Nai-Kuei Huang

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 768 KB

english, 2010

34

In vitro evaluation of bis-pyridinium oximes bearing methoxy alkane linker as reactivators of sarin inhibited human acetylcholinesterase

Jyotiranjan Acharya, Devendra Kumar Dubey, Syed Kalbey Raza

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 467 KB

english, 2010

35

Anti-invasive activity of diallyl disulfide through tightening of tight junctions and inhibition of matrix metalloproteinase activities in LNCaP prostate cancer cells

Dong Yeok Shin, Gi-Young Kim, Jung-In Kim, Moo Kyoung Yoon, Taeg Kyu Kwon, Su Jae Lee, Young-Whan Choi, Ho Sung Kang, Young Hyun Yoo, Yung Hyun Choi

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 996 KB

english, 2010

36

The compound cis-(dichloro)tetrammineruthenium(III) chloride induces caspase-mediated apoptosis in K562 cells

Aliny Pereira de Lima, Flávia de Castro Pereira, Cesar Augusto Sam Tiago Vilanova-Costa, Francyelli Mariana dos Santos Mello, Alessandra de Santana Braga Barbosa Ribeiro, Polyana Lopes Benfica, Marize

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 581 KB

english, 2010

37

Formulation and stability of a novel artificial human sweat under conditions of storage and use

Christopher J. Harvey, Ryan F. LeBouf, Aleksandr B. Stefaniak

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 327 KB

english, 2010

38

Modulation of NAD(P)H:quinone oxidoreductase by vanadium in human hepatoma HepG2 cells

Ghada Abdelhamid, Anwar Anwar-Mohamed, Mohey M. Elmazar, Ayman O.S. El-Kadi

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 678 KB

english, 2010

39

A glycoprotein from Laminaria japonica induces apoptosis in HT-29 colon cancer cells

Hiroe Go, Hye-Jung Hwang, Taek-Jeong Nam

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 941 KB

english, 2010

40

Effects of 17β-estradiol and xenoestrogens on mouse embryonic stem cells

Eui-Man Jung, Kyung-Chul Choi, Frank H Yu, Eui-Bae Jeung

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 1.34 MB

english, 2010

41

Involvement of aryl hydrocarbon receptor in basal and 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced expression of target genes in primary human hepatocytes

Marc Le Vee, Elodie Jouan, Olivier Fardel

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 442 KB

english, 2010

42

Application of a multiple endpoint bacterial reporter assay to evaluate toxicological relevant endpoints of perfluorinated compounds with different functional groups and varying chain length

Ingrid Nobels, Freddy Dardenne, Wim De Coen, Ronny Blust

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 691 KB

english, 2010

43

Effect of cadmium on cortisol production and 11β-hydroxysteroid dehydrogenase 2 expression by cultured human choriocarcinoma cells (JEG-3)

Ana Maria Ronco, Emanuel Llaguno, Maria Jose Epuñan, Miguel N. Llanos

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 428 KB

english, 2010

44

In vitro mutagenicity assessment of aluminium oxide nanomaterials using the Salmonella/microsome assay

A. Balasubramanyam, N. Sailaja, M. Mahboob, M.F. Rahman, Saber M. Hussain, Paramjit Grover

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 343 KB

english, 2010

45

Chromate-induced sulfur starvation and mRNA mistranslation in yeast are linked in a common mechanism of Cr toxicity

Sara L. Holland, Ekalabya Ghosh, Simon V. Avery

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 420 KB

english, 2010

46

Inhibition of in vitro cytokine production by human peripheral blood mononuclear cells treated with xenobiotics: Implications for the prediction of general toxicity and immunotoxicity

Ron Kooijman, Sabrina Devos, Elisabeth Hooghe-Peters

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 257 KB

english, 2010

47

Biological effects and comparative cytotoxicity of thermal transformed asbestos-containing materials in a human alveolar epithelial cell line

Federica Giantomassi, Alessandro F. Gualtieri, Lory Santarelli, Marco Tomasetti, Gigliola Lusvardi, Guendalina Lucarini, Mario Governa, Armanda Pugnaloni

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 2.67 MB

english, 2010

48

Oxidative stress induction by nanoparticles in THP-1 cells with 4-HNE production: Stress biomarker or oxidative stress signalling molecule?

L. Foucaud, S. Goulaouic, A. Bennasroune, P. Laval-Gilly, D. Brown, V. Stone, J. Falla

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 678 KB

english, 2010

49

A lysosomal–mitochondrial death pathway is induced by solamargine in human K562 leukemia cells

Lingmei Sun, Ying Zhao, Xia Li, Huiqing Yuan, Aixia Cheng, Hongxiang Lou

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 1.02 MB

english, 2010

50

Human neuroblastoma cells transfected with tyrosine hydroxylase gain increased resistance to methylmercury-induced cell death

Thaís Posser, Peter R. Dunkley, Phillip W. Dickson, Jeferson Luis Franco

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 503 KB

english, 2010

51

Responses of hepatocytes to DDT and methyl mercury exposure

D. Bussolaro, F. Filipak Neto, C.A. Oliveira Ribeiro

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 492 KB

english, 2010

52

Cytotoxicity of berberine on human cervical carcinoma HeLa cells through mitochondria, death receptor and MAPK pathways, and in-silico drug-target prediction

Binan Lu, Mingming Hu, Kexin liu, Jinyong Peng

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 1.47 MB

english, 2010

53

Reversal of P-glycoprotein-mediated multidrug resistance in vitro by milbemycin compounds in adriamycin-resistant human breast carcinoma (MCF-7/adr) cells

Wensheng Xiang, Aili Gao, Hongsheng Liang, Changyu Li, Jiguo Gao, Qing Wang, Bao Shuang, Ji Zhang, Yijun Yan, Xiangjing Wang

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 700 KB

english, 2010

54

Editorial Board/Publication Information

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 36 KB

english, 2010