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Volume 11; Issue 1

Main
Trials
Volume 11; Issue 1

Trials

Volume 11; Issue 1

1

A prospective evaluation of the safety and efficacy of the TAXUS Element paclitaxel-eluting coronary stent system for the treatment of de novo coronary artery lesions: Design and statistical methods of the PERSEUS clinical program

Dominic J Allocco, Louis A Cannon, Amy Britt, John E Heil, Andrey Nersesov, Scott Wehrenberg, Keith D Dawkins, Dean J Kereiakes

Journal:

Year:

2010

Language:

english

File:

PDF, 1.27 MB

english, 2010

2

The STRIPES Trial - Support to Rural India's Public Education System

Alex Eble, Vera Mann, Preetha Bhakta, Rashmi Lakshminarayana, Chris Frost, Diana Elbourne, Peter Boone

Journal:

Year:

2010

Language:

english

File:

PDF, 269 KB

english, 2010

3

Study protocol for the evaluation of an Infant Simulator based program delivered in schools: a pragmatic cluster randomised controlled trial

Sally A Brinkman, Sarah E Johnson, David Lawrence, James P Codde, Michael B Hart, Judith AY Straton, Sven Silburn

Journal:

Year:

2010

Language:

english

File:

PDF, 458 KB

english, 2010

4

Guided self-help on the internet for turkish migrants with depression: the design of a randomized controlled trial

Burçin Ünlü, Heleen Riper, Annemieke van Straten, Pim Cuijpers

Journal:

Year:

2010

Language:

english

File:

PDF, 474 KB

english, 2010

5

CRIMSON [CRisis plan IMpact: Subjective and Objective coercion and eNgagement] Protocol: A randomised controlled trial of joint crisis plans to reduce compulsory treatment of people with psychosis

Graham Thornicroft, Simone Farrelly, Max Birchwood, Max Marshall, George Szmukler, Waquas Waheed, Sarah Byford, Graham Dunn, Claire Henderson, Helen Lester, Morven Leese, Diana Rose, Kim Sutherby

Journal:

Year:

2010

Language:

english

File:

PDF, 278 KB

english, 2010

6

Can a management pathway for chronic cough in children improve clinical outcomes: protocol for a multicentre evaluation

AB Chang, CF Robertson, PP van Asperen, NJ Glasgow, IB Masters, CM Mellis, LI Landau, L Teoh, PS Morris

Journal:

Year:

2010

Language:

english

File:

PDF, 1.10 MB

english, 2010

7

Compassionate use of interventions: results of a European Clinical Research Infrastructures Network (ECRIN) survey of ten European countries

Kate Whitfield, Karl-Heinz Huemer, Diana Winter, Steffen Thirstrup, Christian Libersa, Béatrice Barraud, Christine Kubiak, Lea Stankovski, Xina Grählert, Gabriele Dreier, Sebastian Geismann, Wolfgang

Journal:

Year:

2010

Language:

english

File:

PDF, 286 KB

english, 2010

8

Physical activity as a treatment for depression: the TREAD randomised trial protocol

Helen Baxter, Rachel Winder, Melanie Chalder, Christine Wright, Sofie Sherlock, Anne Haase, Nicola J Wiles, Alan A Montgomery, Adrian H Taylor, Ken R Fox, Debbie A Lawlor, Tim J Peters, Deborah J Shar

Journal:

Year:

2010

Language:

english

File:

PDF, 295 KB

english, 2010

9

The influence of a biopsychosocial-based treatment approach to primary overt hypothyroidism: a protocol for a pilot study

Benjamin T Brown, Rod Bonello, Henry Pollard, Petra Graham

Journal:

Year:

2010

Language:

english

File:

PDF, 297 KB

english, 2010

10

Acupuncture for dry eye: a multicentre randomised controlled trial with active comparison intervention (artificial tear drop) using a mixed method approach protocol

Tae-Hun Kim, Jung Won Kang, Kun Hyung Kim, Kyung-Won Kang, Mi-Suk Shin, So-Young Jung, Ae-Ran Kim, Hee-Jung Jung, Seung-Deok Lee, Jin-Bong Choi, Sun-Mi Choi

Journal:

Year:

2010

Language:

english

File:

PDF, 448 KB

english, 2010

11

Statistical design of personalized medicine interventions: The Clarification of Optimal Anticoagulation through Genetics (COAG) trial

Benjamin French, Jungnam Joo, Nancy L Geller, Stephen E Kimmel, Yves Rosenberg, Jeffrey L Anderson, Brian F Gage, Julie A Johnson, Jonas H Ellenberg, the COAG (Clarification of Optimal Anticoagulation

Journal:

Year:

2010

Language:

english

File:

PDF, 340 KB

english, 2010

12

Comparison of the collagen haemostat Sangustop®versus a carrier-bound fibrin sealant during liver resection; ESSCALIVER-Study

Christian Moench, Wolf O Bechstein, Valentin Hermanutz, Godehard Hoexter, Hanns-Peter Knaebel

Journal:

Year:

2010

Language:

english

File:

PDF, 390 KB

english, 2010

13

Feasibility study to inform the design of a randomised controlled trial to eradicatePseudomonas aeruginosainfection in individuals with Cystic Fibrosis

Helen R Hickey, Ashley P Jones, Warren Lenney, Paula R Williamson, Rosalind L Smyth

Journal:

Year:

2010

Language:

english

File:

PDF, 275 KB

english, 2010

14

Interaction between drug and placebo effects: a cross-over balanced placebo design trial

Muhammad M Hammami, Eman A Al-Gaai, Syed Alvi, Muhammad B Hammami

Journal:

Year:

2010

Language:

english

File:

PDF, 778 KB

english, 2010

15

The impact of care pathways for exacerbation of Chronic Obstructive Pulmonary Disease: rationale and design of a cluster randomized controlled trial

Kris Vanhaecht, Walter Sermeus, Jan Peers, Cathy Lodewijckx, Svin Deneckere, Fabrizio Leigheb, Marc Decramer, Massimiliano Panella, the EQCP Study Group

Journal:

Year:

2010

Language:

english

File:

PDF, 549 KB

english, 2010

16

Sharing clinical research data in the United States under the health insurance portability and accountability act and the privacy rule

Journal:

Year:

2010

Language:

english

File:

PDF, 217 KB

english, 2010

17

Can herpes simplex virus type 2 suppression slow HIV disease progression: a study protocol for the VALacyclovir In Delaying Antiretroviral Treatment Entry (VALIDATE) trial

Darrell HS Tan, Janet M Raboud, Rupert Kaul, Beatriz Grinsztejn, Pedro Cahn, Sharon L Walmsley

Journal:

Year:

2010

Language:

english

File:

PDF, 590 KB

english, 2010

18

Protocol for a randomised controlled trial of a school based cognitive behaviour therapy (CBT) intervention to prevent depression in high risk adolescents (PROMISE)

Paul Stallard, Alan A Montgomery, Ricardo Araya, Rob Anderson, Glynn Lewis, Kapil Sayal, Rhiannon Buck, Abigail Millings, John A Taylor

Journal:

Year:

2010

Language:

english

File:

PDF, 244 KB

english, 2010

19

A GP caregiver needs toolkit versus usual care in the management of the needs of caregivers of patients with advanced cancer: a randomized controlled trial

Geoffrey Mitchell, Afaf Girgis, Moyez Jiwa, David Sibbritt, Letitia Burridge

Journal:

Year:

2010

Language:

english

File:

PDF, 283 KB

english, 2010

20

Participants' preference for type of leaflet used to feed back the results of a randomised trial: a survey

Stephen Brealey, Lazaros Andronis, Laura Dennis, Christine Atwell, Stirling Bryan, Simon Coulton, Helen Cox, Ben Cross, Fiona Fylan, Andrew Garratt, Fiona Gilbert, Maureen Gillan, Maggie Hendry, Keren

Journal:

Year:

2010

Language:

english

File:

PDF, 280 KB

english, 2010

21

A study of the perceived risks, benefits and barriers to the use of SDD in adult critical care units (The SuDDICU study)

BH Cuthbertson, J Francis, MK Campbell, L MacIntyre, I Seppelt, J Grimshaw, the SuDDICU study groups

Journal:

Year:

2010

Language:

english

File:

PDF, 611 KB

english, 2010

22

Strengthening health human resources and improving clinical outcomes through an integrated guideline and educational outreach in resource-poor settings: a cluster-randomized trial

Michael J Schull, Hastings Banda, Damson Kathyola, Lara Fairall, Alexandra Martiniuk, Barry Burciul, Merrick Zwarenstein, Sumeet Sodhi, Sandy Thompson, Martias Joshua, Martha Mondiwa, Eric Bateman

Journal:

Year:

2010

Language:

english

File:

PDF, 254 KB

english, 2010

23

PRALIMAP: study protocol for a high school-based, factorial cluster randomised interventional trial of three overweight and obesity prevention strategies

Serge Briançon, Emilie Bonsergent, Nelly Agrinier, Sabrina Tessier, Karine Legrand, Edith Lecomte, Evelyne Aptel, Serge Hercberg, Jean-François Collin, PRALIMAP Trial Group

Journal:

Year:

2010

Language:

english

File:

PDF, 421 KB

english, 2010

24

The EVERT (effective verruca treatments) trial protocol: a randomised controlled trial to evaluate cryotherapy versus salicylic acid for the treatment of verrucae

E Sarah Cockayne

Journal:

Year:

2010

Language:

english

File:

PDF, 241 KB

english, 2010

25

The fitness for the Ageing Brain Study II (FABS II): protocol for a randomized controlled clinical trial evaluating the effect of physical activity on cognitive function in patients with Alzheimer's disease

Elizabeth V Cyarto, Kay L Cox, Osvaldo P Almeida, Leon Flicker, David Ames, Gerard Byrne, Keith D Hill, Christopher D Beer, Dina LoGiudice, Kana Appadurai, Muireann Irish, Emma Renehan, Nicola T Laute

Journal:

Year:

2010

Language:

english

File:

PDF, 342 KB

english, 2010

26

Comparison of heat-sensitive moxibustion versus fluticasone/salmeterol (seretide) combination in the treatment of chronic persistent asthma: design of a multicenter randomized controlled trial

Rixin Chen, Mingren Chen, Jun Xiong, Fan Yi, Zhenhai Chi, Bo Zhang

Journal:

Year:

2010

Language:

english

File:

PDF, 416 KB

english, 2010

27

The prevention of contrast induced nephropathy by sarpogrelate in patients with chronic kidney disease: a study protocol for a prospective randomized controlled clinical trial

Kyungil Park, Woo-Young Chung, Jae-Bin Seo, Sang-Hyun Kim, Joo-Hee Zo, Myung-A Kim, Young-Bae Park

Journal:

Year:

2010

Language:

english

File:

PDF, 447 KB

english, 2010

28

Cognitive behavioural therapy versus supportive therapy for persistent positive symptoms in psychotic disorders: The POSITIVE Study, a multicenter, prospective, single-blind, randomised controlled clinical trial

Stefan Klingberg, Andreas Wittorf, Christoph Meisner, Wolfgang Wölwer, Georg Wiedemann, Jutta Herrlich, Andreas Bechdolf, Bernhard W Müller, Gudrun Sartory, Michael Wagner, Tilo Kircher, Hans-Helmut K

Journal:

Year:

2010

Language:

english

File:

PDF, 699 KB

english, 2010

29

Evidence-based interventions in dementia: A pragmatic cluster-randomised trial of an educational intervention to promote earlier recognition and response to dementia in primary care (EVIDEM-ED)

Steve Iliffe, Jane Wilcock, Mark Griffin, Priya Jain, Ingela Thuné-Boyle, Tamar Koch, Frances Lefford

Journal:

Year:

2010

Language:

english

File:

PDF, 570 KB

english, 2010

30

Effects of a mouthwash with chlorine dioxide on oral malodor and salivary bacteria: a randomized placebo-controlled 7-day trial

Kayoko Shinada, Masayuki Ueno, Chisato Konishi, Sachiko Takehara, Sayaka Yokoyama, Takashi Zaitsu, Mari Ohnuki, Allan Clive Fredrick Wright, Yoko Kawaguchi

Journal:

Year:

2010

Language:

english

File:

PDF, 338 KB

english, 2010

31

The randomized shortened dental arch study (RaSDA): design and protocol

Ralph G Luthardt, Birgit Marré, Achim Heinecke, Joachim Gerss, Hans Aggstaller, Eckhard Busche, Paul Dressler, Ingrid Gitt, Wolfgang Hannak, Sinsa Hartmann, Guido Heydecke, Florentine Jahn, Matthias K

Journal:

Year:

2010

Language:

english

File:

PDF, 769 KB

english, 2010

32

Rationale and design of the ADDITION-Leicester study, a systematic screening programme and Randomised Controlled Trial of multi-factorial cardiovascular risk intervention in people with Type 2 Diabetes Mellitus detected by screening

DR Webb, K Khunti, B Srinivasan, LJ Gray, N Taub, S Campbell, J Barnett, J Henson, S Hiles, A Farooqi, SJ Griffin, NJ Wareham, MJ Davies

Journal:

Year:

2010

Language:

english

File:

PDF, 860 KB

english, 2010

33

A systematic review of techniques and interventions for improving adherence to inclusion and exclusion criteria during enrolment into randomised controlled trials

Fiona Simpson, Elizabeth A Sweetman, Gordon S Doig

Journal:

Year:

2010

Language:

english

File:

PDF, 466 KB

english, 2010

34

The effectiveness of joint crisis plans for people with borderline personality disorder: protocol for an exploratory randomised controlled trial

Paul Moran, Rohan Borschmann, Clare Flach, Barbara Barrett, Sarah Byford, Joanna Hogg, Morven Leese, Kim Sutherby, Claire Henderson, Diana Rose, Mike Slade, George Szmukler, Graham Thornicroft

Journal:

Year:

2010

Language:

english

File:

PDF, 297 KB

english, 2010

35

Prevention of depression and sleep disturbances in elderly with memory-problems by activation of the biological clock with light - a randomized clinical trial

Els IS Most, Philip Scheltens, Eus JW Van Someren

Journal:

Year:

2010

Language:

english

File:

PDF, 443 KB

english, 2010

36

Questionnaires in clinical trials: guidelines for optimal design and administration

Journal:

Year:

2010

Language:

english

File:

PDF, 249 KB

english, 2010

37

Applicability and generalisability of the results of systematic reviews to public health practice and policy: a systematic review

Nizar Ahmad, Isabelle Boutron, Agnès Dechartres, Pierre Durieux, Philippe Ravaud

Journal:

Year:

2010

Language:

english

File:

PDF, 467 KB

english, 2010

38

Rationale and design of the randomised clinical trial comparing early medication change (EMC) strategy with treatment as usual (TAU) in patients with Major Depressive Disorder - the EMC trial

André Tadić, Stanislav Gorbulev, Norbert Dahmen, Christoph Hiemke, Dieter F Braus, Joachim Röschke, Dietrich van Calker, Daniel Wachtlin, Kai Kronfeld, Thorsten Gorbauch, Monika Seibert-Grafe, Klaus L

Journal:

Year:

2010

Language:

english

File:

PDF, 926 KB

english, 2010

39

Studying a disease with no home - lessons in trial recruitment from the PATCH II study

Kim S Thomas, the UK Dermatology Clinical Trials Network's PATCH study group

Journal:

Year:

2010

Language:

english

File:

PDF, 243 KB

english, 2010

40

Correction: Protocol for the PINCER trial: a cluster randomised trial comparing the effectiveness of a pharmacist-led IT-based intervention with simple feedback in reducing rates of clinically important errors in medicines management in general practices

Anthony J Avery, Sarah Rodgers, Judith A Cantrill, Sarah Armstrong, Rachel Elliott, Rachel Howard, Denise Kendrick, Caroline J Morris, Scott A Murray, Robin J Prescott, Kathrin Cresswell, Aziz Sheikh

Journal:

Year:

2010

Language:

english

File:

PDF, 153 KB

english, 2010

41

Individualized chiropractic and integrative care for low back pain: the design of a randomized clinical trial using a mixed-methods approach

Kristine K Westrom, Michele J Maiers, Roni L Evans, Gert Bronfort

Journal:

Year:

2010

Language:

english

File:

PDF, 321 KB

english, 2010

42

The effectiveness of a web-based self-help intervention to reduce suicidal thoughts: A randomized controlled trial

Bregje AJ van Spijker, Annemieke van Straten, Ad JFM Kerkhof

Journal:

Year:

2010

Language:

english

File:

PDF, 265 KB

english, 2010

43

Protocol for a pilot randomised controlled clinical trial to compare the effectiveness of a graduated three layer straight tubular bandaging system when compared to a standard short stretch compression bandaging system in the management of people with venous ulceration: 3VSS2008

Carolina D Weller, Sue Evans, Christopher M Reid, Rory Wolfe, John McNeil

Journal:

Year:

2010

Language:

english

File:

PDF, 303 KB

english, 2010

44

JinQi-Jiangtang tablet, a Chinese patent medicine, for pre-diabetes: a randomized controlled trial

Hongbo Cao, Ming Ren, Liping Guo, Hongcai Shang, Junhua Zhang, Yuzhen Song, Hui Wang, Baohe Wang, Xiantao Li, Jing Hu, Xuemei Wang, Dehui Wang, Jianzong Chen, Shuanglei Li, Liming Chen

Journal:

Year:

2010

Language:

english

File:

PDF, 908 KB

english, 2010

45

Obstacles to researching the researchers: A case study of the ethical challenges of undertaking methodological research investigating the reporting of randomised controlled trials

Joanne E McKenzie, G Peter Herbison, Paul Roth, Charlotte Paul

Journal:

Year:

2010

Language:

english

File:

PDF, 1014 KB

english, 2010

46

Improvement of pain related self management for oncologic patients through a trans institutional modular nursing intervention: protocol of a cluster randomized multicenter trial

Patrick Jahn, Maria Kitzmantel, Petra Renz, Ene Kukk, Oliver Kuss, Anette Thoke-Colberg, Ingrid Horn, Margarete Landenberger

Journal:

Year:

2010

Language:

english

File:

PDF, 1.24 MB

english, 2010

47

Losartan therapy in adults with Marfan syndrome: study protocol of the multi-center randomized controlled COMPARE trial

Teodora Radonic, Piet de Witte, Marieke JH Baars, Aeilko H Zwinderman, Barbara JM Mulder, Maarten Groenink, COMPARE study group

Journal:

Year:

2010

Language:

english

File:

PDF, 422 KB

english, 2010

48

A single blind randomized controlled trial of cognitive behavioural therapy in a help-seeking population with an At Risk Mental State for psychosis: the Dutch Early Detection and Intervention Evaluation (EDIE-NL) trial

Judith Rietdijk, Sara Dragt, Rianne Klaassen, Helga Ising, Dorien Nieman, Lex Wunderink, Philippe Delespaul, Pim Cuijpers, Don Linszen, Mark van der Gaag

Journal:

Year:

2010

Language:

english

File:

PDF, 273 KB

english, 2010

49

Reasons for participating in randomised controlled trials: conditional altruism and considerations for self

Sharon K McCann, Marion K Campbell, Vikki A Entwistle

Journal:

Year:

2010

Language:

english

File:

PDF, 1.87 MB

english, 2010

50

CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials

Kenneth F Schulz, Douglas G Altman, David Moher, the CONSORT Group

Journal:

Year:

2010

Language:

english

File:

PDF, 587 KB

english, 2010

51

Cars, CONSORT 2010, and Clinical Practice

Hywel C Williams

Journal:

Year:

2010

Language:

english

File:

PDF, 216 KB

english, 2010

52

Bojungikgitang and banhabaekchulchonmatang in adult patients with tinnitus, a randomized, double-blind, three-arm, placebo-controlled trial - study protocol

Nam-Kwen Kim, Dong-Hyo Lee, Jung-Hun Lee, Yong-Leol Oh, In-Hwan Yoon, Eun-Sung Seo, Chung-Ho Lee

Journal:

Year:

2010

Language:

english

File:

PDF, 411 KB

english, 2010

53

Rationale and design: telephone-delivered behavioral skills interventions for African Americans with type 2 diabetes

Leonard E Egede, Joni L Strom, Valerie L Durkalski, Patrick D Mauldin, William P Moran

Journal:

Year:

2010

Language:

english

File:

PDF, 356 KB

english, 2010

54

Comparison of yoga versus stretching for chronic low back pain: protocol for the Yoga Exercise Self-care (YES) trial

Karen J Sherman, Daniel C Cherkin, Andrea J Cook, Rene J Hawkes, Richard A Deyo, Robert Wellman, Partap S Khalsa

Journal:

Year:

2010

Language:

english

File:

PDF, 918 KB

english, 2010

55

Reporting bias in medical research - a narrative review

Natalie McGauran, Beate Wieseler, Julia Kreis, Yvonne-Beatrice Schüler, Heike Kölsch, Thomas Kaiser

Journal:

Year:

2010

Language:

english

File:

PDF, 1.25 MB

english, 2010

56

Does a colour-coded blood pressure diary improve blood pressure control for patients in general practice: The CoCo trial

Claudia Steurer-Stey, Marco Zoller, Corinne Chmiel Moshinsky, Oliver Senn, Thomas Rosemann

Journal:

Year:

2010

Language:

english

File:

PDF, 447 KB

english, 2010

57

The Health Informatics Trial Enhancement Project (HITE): Using routinely collected primary care data to identify potential participants for a depression trial

Joanna McGregor, Caroline Brooks, Padmaja Chalasani, Jude Chukwuma, Hayley Hutchings, Ronan A Lyons, Keith Lloyd

Journal:

Year:

2010

Language:

english

File:

PDF, 376 KB

english, 2010

58

Alberta Diabetes and Physical Activity Trial (ADAPT): A randomized theory-based efficacy trial for adults with type 2 diabetes - rationale, design, recruitment, evaluation, and dissemination

Ronald C Plotnikoff, Kerry S Courneya, Ronald J Sigal, Jeffrey A Johnson, Nicholas Birkett, David Lau, Kim Raine, Steven T Johnson, Nandini Karunamuni

Journal:

Year:

2010

Language:

english

File:

PDF, 557 KB

english, 2010

59

The WOMAN Trial (World Maternal Antifibrinolytic Trial): tranexamic acid for the treatment of postpartum haemorrhage: an international randomised, double blind placebo controlled trial

Haleema Shakur, Diana Elbourne, Metin Gülmezoglu, Zarko Alfirevic, Carine Ronsmans, Elizabeth Allen, Ian Roberts

Journal:

Year:

2010

Language:

english

File:

PDF, 929 KB

english, 2010

60

A pragmatic multi-centre randomised controlled trial of fluid loading and level of dependency in high-risk surgical patients undergoing major elective surgery: trial protocol

Brian H Cuthbertson, Marion K Campbell, Stephen A Stott, Luke Vale, John Norrie, John Kinsella, Jonathan Cook, Julie Brittenden, Adrian Grant, FOCCUS Study Group

Journal:

Year:

2010

Language:

english

File:

PDF, 395 KB

english, 2010

61

The SINS trial: A randomised controlled trial of excisional surgery versus imiquimod 5% cream for nodular and superficial basal cell carcinoma

Mara Ozolins, Hywel C Williams, Sarah J Armstrong, Fiona J Bath-Hextall

Journal:

Year:

2010

Language:

english

File:

PDF, 409 KB

english, 2010

62

Evaluation of a toolkit to improve cardiovascular disease screening and treatment for people with type 2 diabetes: protocol for a cluster-randomized pragmatic trial

Baiju R Shah, Onil Bhattacharyya, Catherine Yu, Muhammad Mamdani, Janet A Parsons, Sharon E Straus, Merrick Zwarenstein

Journal:

Year:

2010

Language:

english

File:

PDF, 619 KB

english, 2010

63

Comparative effectiveness research: Challenges for medical journals

Harold C Sox, Mark Helfand, Jeremy Grimshaw, Kay Dickersin, The PLoS Medicine Editors, David Tovey, J André Knottnerus, Peter Tugwell

Journal:

Year:

2010

Language:

english

File:

PDF, 269 KB

english, 2010

64

Maintenance Cognitive Stimulation Therapy (CST) for dementia: A single-blind, multi-centre, randomized controlled trial of Maintenance CST vs. CST for dementia

Elisa Aguirre, Aimee Spector, Juanita Hoe, Ian T Russell, Martin Knapp, Robert T Woods, Martin Orrell

Journal:

Year:

2010

Language:

english

File:

PDF, 875 KB

english, 2010

65

ChroPac-Trial: Duodenum-preserving pancreatic head resection versus pancreatoduodenectomy for chronic pancreatitis. Trial protocol of a randomised controlled multicentre trial

Markus K Diener, Thomas Bruckner, Pietro Contin, Christopher Halloran, Matthias Glanemann, Hans Jürgen Schlitt, Joachim Mössner, Meinhard Kieser, Jens Werner, Markus W Büchler, Christoph M Seiler

Journal:

Year:

2010

Language:

english

File:

PDF, 981 KB

english, 2010

66

Protocol for a randomised controlled trial investigating the effectiveness of an online e-health application compared to attention placebo or sertraline in the treatment of generalised anxiety disorder

Helen Christensen, Adam J Guastella, Andrew J Mackinnon, Kathleen M Griffiths, Claire Eagleson, Philip J Batterham, Kanupriya Kalia, Justin Kenardy, Kylie Bennett, Ian B Hickie

Journal:

Year:

2010

Language:

english

File:

PDF, 584 KB

english, 2010

67

Multicenter data acquisition made easy

Jacob Rosenberg, Abdelaal Nadia Henriksen, Lars Nannestad Jørgensen

Journal:

Year:

2010

Language:

english

File:

PDF, 475 KB

english, 2010

68

Improving the management of non-ST elevation acute coronary syndromes: systematic evaluation of a quality improvement programmeEuropeanQUalityImprovementProgramme forAcuteCoronarySyndrome: The EQUIP-ACS project protocol and design

Marcus D Flather, Jean Booth, Daphne Babalis, Hector Bueno, Philippe G Steg, Grzegorz Opolski, Filippo Ottani, Jacques Machecourt, Alfredo Bardaji, Mats Bojestig, Anthony R Brady, Bertil Lindahl

Journal:

Year:

2010

Language:

english

File:

PDF, 506 KB

english, 2010

69

The SPARK Study: a phase II randomized blinded controlled trial of the effect of furosemide in critically ill patients with early acute kidney injury

Sean M Bagshaw, RT Noel Gibney, Finlay A McAlister, Rinaldo Bellomo

Journal:

Year:

2010

Language:

english

File:

PDF, 737 KB

english, 2010

70

A randomised controlled trial of antiplatelet therapy in combination with Rt-PA thrombolysis in ischemic stroke: rationale and design of the ARTIS-Trial

SM Zinkstok, M Vermeulen, J Stam, RJ de Haan, YB Roos

Journal:

Year:

2010

Language:

english

File:

PDF, 447 KB

english, 2010

71

Assessing the potential for outcome reporting bias in a review: a tutorial

Kerry Dwan, Carrol Gamble, Ruwanthi Kolamunnage-Dona, Shabana Mohammed, Colin Powell, Paula R Williamson

Journal:

Year:

2010

Language:

english

File:

PDF, 377 KB

english, 2010

72

Evaluation of exercise on individuals with dementia and their carers: a randomised controlled trial

Arlinda Cerga-Pashoja, David Lowery, Rahul Bhattacharya, Mark Griffin, Steve Iliffe, James Lee, Claire Leonard, Sue Ricketts, Lyn Strother, Fiona Waters, Craig W Ritchie, James Warner

Journal:

Year:

2010

Language:

english

File:

PDF, 788 KB

english, 2010

73

Design and implementation of a dental caries prevention trial in remote Canadian Aboriginal communities

Rosamund Harrison, Jacques Veronneau, Brian Leroux

Journal:

Year:

2010

Language:

english

File:

PDF, 524 KB

english, 2010

74

Spatial effects should be allowed for in primary care and other community-based cluster RCTS

Paul Silcocks, Denise Kendrick

Journal:

Year:

2010

Language:

english

File:

PDF, 666 KB

english, 2010

75

Case management for patients with chronic systolic heart failure in primary care: The HICMan exploratory randomised controlled trial

Frank Peters-Klimm, Stephen Campbell, Katja Hermann, Cornelia U Kunz, Thomas Müller-Tasch, Joachim Szecsenyi, the Competence Network Heart Failure

Journal:

Year:

2010

Language:

english

File:

PDF, 873 KB

english, 2010

76

TheChest Pain Choicetrial: a pilot randomized trial of a decision aid for patients with chest pain in the emergency department

Meghan A Pierce, Erik P Hess, Jeffrey A Kline, Nilay D Shah, Maggie Breslin, Megan E Branda, Laurie J Pencille, Brent R Asplin, David M Nestler, Annie T Sadosty, Ian G Stiell, Henry H Ting, Victor M M

Journal:

Year:

2010

Language:

english

File:

PDF, 658 KB

english, 2010

77

NEWHINTS cluster randomised trial to evaluate the impact on neonatal mortality in rural Ghana of routine home visits to provide a package of essential newborn care interventions in the third trimester of pregnancy and the first week of life: trial protocol

Betty R Kirkwood, Alexander Manu, Charlotte Tawiah-Agyemang, Guus ten Asbroek, Thomas Gyan, Benedict Weobong, R Eric Lewandowski, Seyi Soremekun, Samuel Danso, Catherine Pitt, Kara Hanson, Seth Owusu-

Journal:

Year:

2010

Language:

english

File:

PDF, 819 KB

english, 2010

78

Reporting on covariate adjustment in randomised controlled trials before and after revision of the 2001 CONSORT statement: a literature review

Ly-Mee Yu, An-Wen Chan, Sally Hopewell, Jonathan J Deeks, Douglas G Altman

Journal:

Year:

2010

Language:

english

File:

PDF, 937 KB

english, 2010

79

Multi-centre cluster randomised trial comparing a community group exercise programme with home based exercise with usual care for people aged 65 and over in primary care: protocol of the ProAct 65+ trial

Steve Iliffe, Denise Kendrick, Richard Morris, Dawn Skelton, Heather Gage, Susie Dinan, Zoe Stevens, Mirilee Pearl, Tahir Masud

Journal:

Year:

2010

Language:

english

File:

PDF, 662 KB

english, 2010

80

Taking Action Together: A YMCA-based protocol to prevent Type-2 Diabetes in high-BMI inner-city African American children

Lorrene D Ritchie, Sushma Sharma, Joanne P Ikeda, Rita A Mitchell, Aarthi Raman, Barbara S Green, Mark L Hudes, Sharon E Fleming

Journal:

Year:

2010

Language:

english

File:

PDF, 857 KB

english, 2010

81

Fluvastatin in the first-line therapy of acute coronary syndrome: results of the multicenter, randomized, double-blind, placebo-controlled trial (the FACS-trial)

Petr Ostadal, David Alan, Jiri Vejvoda, Jiri Kukacka, Milan Macek, Petr Hajek, Martin Mates, Milan Kvapil, Jiri Kettner, Martin Wiendl, Ondrej Aschermann, Josef Slaby, Frantisek Holm, Peter Telekes, D

Journal:

Year:

2010

Language:

english

File:

PDF, 899 KB

english, 2010

82

Prospective randomized trial evaluating mandatory second look surgery with HIPEC and CRS vs. standard of care in patients at high risk of developing colorectal peritoneal metastases

Robert T Ripley, Jeremy L Davis, Clinton D Kemp, Seth M Steinberg, Mary Ann Toomey, Itzhak Avital

Journal:

Year:

2010

Language:

english

File:

PDF, 649 KB

english, 2010

83

Dementia in residential care: education intervention trial (DIRECT); protocol for a randomised controlled trial

Christopher D Beer, Barbara Horner, Osvaldo P Almeida, Samuel Scherer, Nicola T Lautenschlager, Nick Bretland, Penelope Flett, Frank Schaper, Leon Flicker

Journal:

Year:

2010

Language:

english

File:

PDF, 479 KB

english, 2010

84

Legislation for trial registration and data transparency

Zhao-Xiang Bian, Tai-Xiang Wu

Journal:

Year:

2010

Language:

english

File:

PDF, 384 KB

english, 2010

85

The BRACELET Study: surveys of mortality in UK neonatal and paediatric intensive care trials

Claire Snowdon, Sheila E Harvey, Peter Brocklehurst, Robert C Tasker, Martin P Ward Platt, Elizabeth Allen, Diana Elbourne

Journal:

Year:

2010

Language:

english

File:

PDF, 805 KB

english, 2010

86

Etoricoxib - preemptive and postoperative analgesia (EPPA) in patients with laparotomy or thoracotomy - design and protocols

Johannes Fleckenstein, Sybille Kramer, Martin Offenbächer, Gabriel Schober, Herbert Plischke, Matthias Siebeck, Thomas Mussack, Rudolf Hatz, Lukas Lehmeyer, Philip M Lang, Bernhard Heindl, Peter Conze

Journal:

Year:

2010

Language:

english

File:

PDF, 634 KB

english, 2010

87

The Viborg vascular (VIVA) screening trial of 65-74 year old men in the central region of Denmark: study protocol

Nikolaj Grøndal, Rikke Søgaard, Eskild W Henneberg, Jes S Lindholt

Journal:

Year:

2010

Language:

english

File:

PDF, 659 KB

english, 2010

88

Efficacy of n-3 polyunsaturated fatty acids and feasibility of optimizing preventive strategies in patients at high cardiovascular risk: rationale, design and baseline characteristics of the Rischio and Prevenzione study, a large randomised trial in general practice

Rischio and Prevenzione Investigators

Journal:

Year:

2010

Language:

english

File:

PDF, 733 KB

english, 2010

89

STOPFLU: is it possible to reduce the number of days off in office work by improved hand-hygiene?

Carita Savolainen-Kopra, Jaason Haapakoski, Piia A Peltola, Thedi Ziegler, Terttu Korpela, Pirjo Anttila, Ali Amiryousefi, Pentti Huovinen, Markku Huvinen, Heikki Noronen, Pia Riikkala, Merja Roivaine

Journal:

Year:

2010

Language:

english

File:

PDF, 742 KB

english, 2010

90

Hand sanitisers for reducing illness absences in primary school children in New Zealand: a cluster randomised controlled trial study protocol

Joanne E McKenzie, Patricia Priest, Rick Audas, Marion R Poore, Cheryl R Brunton, Lesley M Reeves

Journal:

Year:

2010

Language:

english

File:

PDF, 338 KB

english, 2010

91

Effects of the dose of erythropoiesis stimulating agents on cardiovascular events, quality of life, and health-related costs in hemodialysis patients: the clinical evaluation of the dose of erythropoietins (C.E. DOSE) trial protocol

Clinical Evaluation of the DOse of Erythropoietins Study Group (C.E. DOSE), Giovanni FM Strippoli

Journal:

Year:

2010

Language:

english

File:

PDF, 408 KB

english, 2010

92

P3MC: A double blind parallel group randomised placebo controlled trial of Propranolol and Pizotifen in preventing migraine in children

Paul Silcocks, Diane Whitham, William Patrick Whitehouse

Journal:

Year:

2010

Language:

english

File:

PDF, 801 KB

english, 2010

93

LICAVAL: combination therapy in acute and maintenance treatment of bipolar disorder

Rodolfo N Campos, Luis F Costa, Danielle S Bio, Márcio G Soeiro de Souza, Carla RL Garcia, Frederico N Demétrio, Doris H Moreno, Ricardo A Moreno

Journal:

Year:

2010

Language:

english

File:

PDF, 417 KB

english, 2010

94

Development of an awareness-based intervention to enhance quality of life in severe dementia: trial platform

Linda Clare, Robert T Woods, Rhiannon Whitaker, Barbara A Wilson, Murna Downs

Journal:

Year:

2010

Language:

english

File:

PDF, 496 KB

english, 2010

95

Study protocol: home-based telehealth stroke care: a randomized trial for veterans

Neale R Chumbler, Dorian K Rose, Patricia Griffiths, Patricia Quigley, Nancy McGee-Hernandez, Katherine A Carlson, Phyllis Vandenberg, Miriam C Morey, Jon Sanford, Helen Hoenig

Journal:

Year:

2010

Language:

english

File:

PDF, 749 KB

english, 2010

96

Quality of reporting of trial abstracts needs to be improved: using the CONSORT for abstracts to assess the four leading Chinese medical journals of traditional Chinese medicine

Ling Wang, Yulin Li, Jing Li, Mingming Zhang, Lin Xu, Wenming Yuan, Gang Wang, Sally Hopewell

Journal:

Year:

2010

Language:

english

File:

PDF, 437 KB

english, 2010

97

A pragmatic cluster randomized trial evaluating the impact of a community pharmacy intervention on statin adherence: rationale and design of the Community Pharmacy Assisting in Total Cardiovascular Health (CPATCH) study

Charity D Evans, Dean T Eurich, Jeff G Taylor, Alfred J Remillard, Yvonne M Shevchuk, David F Blackburn

Journal:

Year:

2010

Language:

english

File:

PDF, 462 KB

english, 2010

98

Problems in the reporting of acne clinical trials: a spot check from the 2009 Annual Evidence Update on Acne Vulgaris

John R Ingram, Douglas JC Grindlay, Hywel C Williams

Journal:

Year:

2010

Language:

english

File:

PDF, 446 KB

english, 2010

99

Managing clinical trials

Barbara Farrell, Sara Kenyon, Haleema Shakur

Journal:

Year:

2010

Language:

english

File:

PDF, 224 KB

english, 2010

100

Heterogeneity prevails: the state of clinical trial data management in Europe - results of a survey of ECRIN centres

Wolfgang Kuchinke, Christian Ohmann, Qin Yang, Nader Salas, Jens Lauritsen, Francois Gueyffier, Alan Leizorovicz, Carmen Schade-Brittinger, Michael Wittenberg, Zoltán Voko, Siobhan Gaynor, Margaret Co

Journal:

Year:

2010

Language:

english

File:

PDF, 779 KB

english, 2010

101

The B-VITAGE trial: A randomized trial of homocysteine lowering treatment of depression in later life

Andrew H Ford, Leon Flicker, Kieran McCaul, Frank van Bockxmeer, Sarah Hegarty, Varsha Hirani, Stephen Fenner, Osvaldo P Almeida

Journal:

Year:

2010

Language:

english

File:

PDF, 300 KB

english, 2010

102

Protocol for a phase 1 homeopathic drug proving trial

Michael Teut, Ute Hirschberg, Rainer Luedtke, Cristoph Schnegg, Joern Dahler, Henning Albrecht, Claudia M Witt

Journal:

Year:

2010

Language:

english

File:

PDF, 544 KB

english, 2010

103

Decision aid on radioactive iodine treatment for early stage papillary thyroid cancer - a randomized controlled trial

Anna M Sawka, Sharon Straus, James D Brierley, Richard W Tsang, Lorne Rotstein, Gary Rodin, Amiram Gafni, Shereen Ezzat, Lehana Thabane, Kevin E Thorpe, David P Goldstein

Journal:

Year:

2010

Language:

english

File:

PDF, 306 KB

english, 2010

104

The effects of a muscle resistance program on the functional capacity, knee extensor muscle strength and plasma levels of IL-6 and TNF-α in pre-frail elderly women: a randomized crossover clinical trial - a study protocol

Lygia P Lustosa, Fernanda M Coelho, Juscelio P Silva, Daniele S Pereira, Adriana N Parentoni, João MD Dias, Rosangela C Dias, Leani SM Pereira

Journal:

Year:

2010

Language:

english

File:

PDF, 377 KB

english, 2010

105

Banha-sasim-tangas an herbal formula for the treatment of functional dyspepsia: a randomized, double-blind, placebo-controlled, two-center trial

Jae-Woo Park, Bongha Ryu, Inkwon Yeo, Ui-Min Jerng, Gajin Han, Sunghwan Oh, Jinsoo Lee, Jinsung Kim

Journal:

Year:

2010

Language:

english

File:

PDF, 462 KB

english, 2010

106

Protocol for the adolescent hayfever trial: cluster randomised controlled trial of an educational intervention for healthcare professionals for the management of school-age children with hayfever

Victoria S Hammersley, Samantha Walker, Rob Elton, Aziz Sheikh

Journal:

Year:

2010

Language:

english

File:

PDF, 268 KB

english, 2010

107

Assessing and reporting heterogeneity in treatment effects in clinical trials: a proposal

David M Kent, Peter M Rothwell, John PA Ioannidis, Doug G Altman, Rodney A Hayward

Journal:

Year:

2010

Language:

english

File:

PDF, 348 KB

english, 2010

108

A randomised controlled trial to evaluate the efficacy of a 6 month dietary and physical activity intervention for prostate cancer patients receiving androgen deprivation therapy

Farhana Haseen, Liam J Murray, Roisin F O'Neill, Joe M O'Sullivan, Marie M Cantwell

Journal:

Year:

2010

Language:

english

File:

PDF, 528 KB

english, 2010

109

Study design and rationale of 'Influence of Cilostazol-based triple anti-platelet therapy on ischemic complication after drug-eluting stent implantation (CILON-T)' study: A multicenter randomized trial evaluating the efficacy of Cilostazol on ischemic vascular complications after drug-eluting stent implantation for coronary heart disease

Seung-Pyo Lee, Jung-Won Suh, Kyung Woo Park, Hae-Young Lee, Hyun-Jae Kang, Bon-Kwon Koo, In-Ho Chae, Dong-Ju Choi, Seung-Woon Rha, Jang-Whan Bae, Myeong-Chan Cho, Taek-Geun Kwon, Jang-Ho Bae, Hyo-Soo

Journal:

Year:

2010

Language:

english

File:

PDF, 586 KB

english, 2010

110

A cluster randomised controlled trial of the community effectiveness of two interventions in rural Malawi to improve health care and to reduce maternal, newborn and infant mortality

Sonia Lewycka, Charles Mwansambo, Peter Kazembe, Tambosi Phiri, Andrew Mganga, Mikey Rosato, Hilda Chapota, Florida Malamba, Stefania Vergnano, Marie-Louise Newell, David Osrin, Anthony Costello

Journal:

Year:

2010

Language:

english

File:

PDF, 1.70 MB

english, 2010

111

Rationale and design of EXPLORE: a randomized, prospective, multicenter trial investigating the impact of recanalization of a chronic total occlusion on left ventricular function in patients after primary percutaneous coronary intervention for acute ST-elevation myocardial infarction

René J van der Schaaf, Bimmer E Claessen, Loes P Hoebers, Niels J Verouden, Jacques J Koolen, Maarten J Suttorp, Emanuele Barbato, Matthijs Bax, Bradley H Strauss, Göran K Olivecrona, Vegard Tuseth, D

Journal:

Year:

2010

Language:

english

File:

PDF, 500 KB

english, 2010

112

Preparing raw clinical data for publication: guidance for journal editors, authors, and peer reviewers

Iain Hrynaszkiewicz, Melissa L Norton, Andrew J Vickers, Douglas G Altman

Journal:

Year:

2010

Language:

english

File:

PDF, 257 KB

english, 2010

113

Individual patient data meta-analysis of acupuncture for chronic pain: protocol of the Acupuncture Trialists' Collaboration

Andrew J Vickers, Angel M Cronin, Alexandra C Maschino, George Lewith, Hugh Macpherson, Norbert Victor, Karen J Sherman, Claudia Witt, Klaus Linde

Journal:

Year:

2010

Language:

english

File:

PDF, 797 KB

english, 2010

114

A randomized, placebo-controlled, double-blind, prospective trial to evaluate the effect of vildagliptin in new-onset diabetes mellitus after kidney transplantation

Michael Haidinger, Johannes Werzowa, Hans-Christian Voigt, Johannes Pleiner, Gunar Stemer, Manfred Hecking, Dominik Döller, Walter H Hörl, Thomas Weichhart, Marcus D Säemann

Journal:

Year:

2010

Language:

english

File:

PDF, 534 KB

english, 2010

115

Exercise rehabilitation on home-dwelling patients with Alzheimer's disease - a randomized, controlled trial. Study protocol

Kaisu H Pitkala, Minna M Raivio, Marja-Liisa Laakkonen, Reijo S Tilvis, Hannu Kautiainen, Timo E Strandberg

Journal:

Year:

2010

Language:

english

File:

PDF, 691 KB

english, 2010

116

Improving educational achievement and anaemia of school children: design of a cluster randomised trial of school-based malaria prevention and enhanced literacy instruction in Kenya

Simon Brooker, George Okello, Kiambo Njagi, Margaret M Dubeck, Katherine E Halliday, Hellen Inyega, Matthew CH Jukes

Journal:

Year:

2010

Language:

english

File:

PDF, 1.13 MB

english, 2010

117

Trial Protocol: Randomised controlled trial of the effects of very low calorie diet, modest dietary restriction, and sequential behavioural programme on hunger, urges to smoke, abstinence and weight gain in overweight smokers stopping smoking

Deborah Lycett, Peter Hajek, Paul Aveyard

Journal:

Year:

2010

Language:

english

File:

PDF, 506 KB

english, 2010

118

Study protocol: The Adherence and Intensification of Medications (AIM) study - a cluster randomized controlled effectiveness study

Michele Heisler, Timothy P Hofer, Mandi L Klamerus, Julie Schmittdiel, Joe Selby, Mary M Hogan, Hayden B Bosworth, Adam Tremblay, Eve A Kerr

Journal:

Year:

2010

Language:

english

File:

PDF, 1.78 MB

english, 2010

119

Brief cognitive behavioral therapy compared to general practitioners care for depression in primary care: a randomized trial

Kim D Baas, Maarten WJ Koeter, Henk C van Weert, Peter Lucassen, Claudi LH Bockting, Karin A Wittkampf, Aart H Schene

Journal:

Year:

2010

Language:

english

File:

PDF, 272 KB

english, 2010

120

Effects of erythropoietin on depressive symptoms and neurocognitive deficits in depression and bipolar disorder

Kamilla W Miskowiak, Maj Vinberg, Catherine J Harmer, Hannelore Ehrenreich, Gitte M Knudsen, Julian Macoveanu, Allan R Hansen, Olaf B Paulson, Hartwig R Siebner, Lars V Kessing

Journal:

Year:

2010

Language:

english

File:

PDF, 328 KB

english, 2010

121

The addition of a goal-based motivational interview to standardised treatment as usual to reduce dropouts in a service for patients with personality disorder: a feasibility study

Mary McMurran, W Miles Cox, Stephen Coupe, Diane Whitham, Lucy Hedges

Journal:

Year:

2010

Language:

english

File:

PDF, 450 KB

english, 2010

122

Study protocol for a randomized controlled trial comparing mindfulness-based cognitive therapy with maintenance anti-depressant treatment in the prevention of depressive relapse/recurrence: the PREVENT trial

Willem Kuyken, Sarah Byford, Richard Byng, Tim Dalgleish, Glyn Lewis, Rod Taylor, Edward R Watkins, Rachel Hayes, Paul Lanham, David Kessler, Nicola Morant, Alison Evans

Journal:

Year:

2010

Language:

english

File:

PDF, 759 KB

english, 2010

123

A systematic review of clinical trials of pharmacological interventions for acute ischaemic stroke (1955-2008) that were completed, but not published in full

Lorna M Gibson, Miriam Brazzelli, Brenda M Thomas, Peter AG Sandercock

Journal:

Year:

2010

Language:

english

File:

PDF, 1.09 MB

english, 2010