Volume 39; Issue 9

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Xenobiotica
Volume 39; Issue 9

Xenobiotica

Volume 39; Issue 9

1

Effect of continuous silymarin administration on oral talinolol pharmacokinetics in healthy volunteers

Han, Y., Guo, D., Chen, Y., Tan, Z.-R., Zhou, H.-H.

Journal:

Year:

2009

Language:

english

File:

PDF, 734 KB

english, 2009

2

Prediction of Phase I single-dose pharmacokinetics using recombinant cytochromes P450 and physiologically based modelling

Gibson, C. R., Bergman, A., Lu, P., Kesisoglou, F., Denney, W. S., Mulrooney, E.

Journal:

Year:

2009

Language:

english

File:

PDF, 1.06 MB

english, 2009

3

Cytochrome P450-catalysed arene-epoxidation of the bioactive tea tree oil ingredient p- cymene: indication for the formation of a reactive allergenic intermediate?

Meesters, R. J. W., Duisken, M., Hollender, J.

Journal:

Year:

2009

Language:

english

File:

PDF, 846 KB

english, 2009

4

Flavin-containing monooxygenase 1-catalysed N , N -dimethylamphetamine N -oxidation

Lee, S. K., Kang, M. J., Jin, C., In, M. K., Kim, D.-H., Yoo, H. H.

Journal:

Year:

2009

Language:

english

File:

PDF, 941 KB

english, 2009

5

Disposition of GDC-0879, a B-RAF kinase inhibitor in preclinical species

Choo, E. F., Driscoll, J. P., Feng, J., Liederer, B., Plise, E., Randolph, N., Shin, Y., Wong, S., Ran, Y.

Journal:

Year:

2009

Language:

english

File:

PDF, 867 KB

english, 2009

6

Species differences for stereoselective metabolism of ethofumesate and its enantiomers in vitro

Zhu, W., Dang, Z., Qiu, J., Liu, Y., Lv, C., Diao, J., Zhou, Z.

Journal:

Year:

2009

Language:

english

File:

PDF, 776 KB

english, 2009

7

CYP1A2 is the major isoform responsible for paeonol O -demethylation in human liver microsomes

Liu, H.-X., Hu, Y., Liu, Y., He, Y.-Q., Li, W., Yang, L.

Journal:

Year:

2009

Language:

english

File:

PDF, 941 KB

english, 2009

8

Comparison of intrinsic metabolic clearance in fresh and cryopreserved human hepatocytes

Floby, E., Johansson, J., Hoogstraate, J., Hewitt, N. J., Hill, J., Sohlenius-Sternbeck, A.-K.

Journal:

Year:

2009

Language:

english

File:

PDF, 689 KB

english, 2009

9

Utility of unbound plasma drug levels and P-glycoprotein transport data in prediction of central nervous system exposure

He, H., Lyons, K.A., Shen, X., Yao, Z., Bleasby, K., Chan, G., Hafey, M., Li, X., Xu, S., Salituro, G. M., Cohen, L. H., Tang, W.

Journal:

Year:

2009

Language:

english

File:

PDF, 714 KB

english, 2009