Volume 41; Issue 5

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Xenobiotica
Volume 41; Issue 5

Xenobiotica

Volume 41; Issue 5

1

Case report of extensive metabolism by aldehyde oxidase in humans: Pharmacokinetics and metabolite profile of FK3453 in rats, dogs, and humans

Akabane, Takafumi, Tanaka, Kohichiro, Irie, Megumi, Terashita, Shigeyuki, Teramura, Toshio

Journal:

Year:

2011

Language:

english

File:

PDF, 1007 KB

english, 2011

2

In vitro and in vivo pharmacokinetic characterizations of AMG 900, an orally bioavailable small molecule inhibitor of aurora kinases

Huang, Liyue, Be, Xuhai, Berry, Loren, Moore, Earl, Janosky, Brett, Wells, Mary, Pan, Wei-Jian, Zhao, Zhiyang, Lin, Min-Hwa Jasmine

Journal:

Year:

2011

Language:

english

File:

PDF, 741 KB

english, 2011

3

In vitro metabolism of magnolin and characterization of cytochrome P450 enzymes responsible for its metabolism in human liver microsomes

Kim, Dong Kyun, Liu, Kwang-Hyeon, Jeong, Ji Hyun, Ji, Hye Young, Oh, Sei-Ryang, Lee, Hyeong-Kyu, Lee, Hye Suk

Journal:

Year:

2011

Language:

english

File:

PDF, 1.10 MB

english, 2011

4

Effect of pregnancy on topiramate pharmacokinetics in rabbits

Matar, Kamal M., Marafie, Najlaa A.

Journal:

Year:

2011

Language:

english

File:

PDF, 652 KB

english, 2011

5

Absorption, excretion, and metabolism of a potential GABA-A α2/3 receptor modulator in rats

Guo, Jian, Davis, Patty C., Gu, Chungang, Grimm, Scott W.

Journal:

Year:

2011

Language:

english

File:

PDF, 1.14 MB

english, 2011

6

Dalcetrapib pharmacokinetics and metabolism in the cynomolgus monkey

Kuhlmann, Olaf, Heinig, Katja

Journal:

Year:

2011

Language:

english

File:

PDF, 742 KB

english, 2011

7

C5-Hydroxylation of liquiritigenin is catalyzed selectively by CYP1A2

Wang, Ao-Xue, Hu, Ying, Liu, Hui-Xin, Qi, Xiao-Yi, Liu, Yong, Tu, Cai-Xia, Yang, Ling

Journal:

Year:

2011

Language:

english

File:

PDF, 832 KB

english, 2011

8

Organophosphorus pesticide degradation product in vitro metabolic stability and time-course uptake and elimination in rats following oral and intravenous dosing

Forsberg, N. D., Rodriguez-Proteau, R., Ma, L., Morré, J., Christensen, J. M., Maier, C. S., Jenkins, J. J., Anderson, K. A.

Journal:

Year:

2011

Language:

english

File:

PDF, 749 KB

english, 2011

9

Pharmacokinetic interaction between ϵ-acetamidocaproic acid (AACA) and cimetidine in indomethacin-induced acute gastric ulcer and control rats: inhibition of active renal secretion of AACA by cimetidine

Choi, Y. H., Lee, U., Suh, J. H., Kim, Y. G., Lee, M., Oh, E., Lee, M. G.

Journal:

Year:

2011

Language:

english

File:

PDF, 706 KB

english, 2011