Volume 42; Issue 9

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Xenobiotica
Volume 42; Issue 9

Xenobiotica

Volume 42; Issue 9

1

3D-QSAR studies on UDP-glucuronosyltransferase 2B7 substrates using the pharmacophore and VolSurf approaches

Ako, Roland, Dong, Dong, Wu, Baojian

Journal:

Year:

2012

Language:

english

File:

PDF, 1.39 MB

english, 2012

2

Naturally occurring flavonoids as inhibitors of purified cytosolic glutathione S-transferase

Boušová, Iva, Hájek, Jan, Dršata, Jaroslav, Skálová, Lenka

Journal:

Year:

2012

Language:

english

File:

PDF, 819 KB

english, 2012

3

Absorption, distribution, metabolism, and excretion of macitentan, a dual endothelin receptor antagonist, in humans

Bruderer, Shirin, Hopfgartner, Gérard, Seiberling, Michael, Wank, Janine, Sidharta, Patricia N., Treiber, Alexander, Dingemanse, Jasper

Journal:

Year:

2012

Language:

english

File:

PDF, 1.26 MB

english, 2012

4

Hydrophilic anti-migraine triptans are substrates for OATP1A2, a transporter expressed at human blood-brain barrier

Cheng, Ziqiang, Liu, Houfu, Yu, Na, Wang, Fei, An, Gang, Xu, Yan, Liu, Qian, Guan, Chen-bing, Ayrton, Andrew

Journal:

Year:

2012

Language:

english

File:

PDF, 1.98 MB

english, 2012

5

Practical use of the regression offset approach for the prediction of in vivo intrinsic clearance from hepatocytes

Sohlenius-Sternbeck, Anna-Karin, Jones, Christopher, Ferguson, Douglas, Middleton, Brian J., Projean, Denis, Floby, Eva, Bylund, Johan, Afzelius, Lovisa

Journal:

Year:

2012

Language:

english

File:

PDF, 1.10 MB

english, 2012

6

Two novel creatinine adducts of andrographolide in human urine

Qiu, Feng, Cui, Liang, Chen, Lixia, Sun, Jiawen, Yao, Xinsheng

Journal:

Year:

2012

Language:

english

File:

PDF, 879 KB

english, 2012

7

Autoinduction of phase I and phase II metabolism of artemisinin in rats

Xing, J., Du, F. Y., Liu, T., Zhu, F. P.

Journal:

Year:

2012

Language:

english

File:

PDF, 787 KB

english, 2012

8

Protein quantification of UDP-glucuronosyltransferases 1A1 and 2B7 in human liver microsomes by LC-MS/MS and correlation with glucuronidation activities

Sato, Yuichiro, Nagata, Masanori, Kawamura, Akio, Miyashita, Aiji, Usui, Takashi

Journal:

Year:

2012

Language:

english

File:

PDF, 913 KB

english, 2012

9

Use of uptake intrinsic clearance from attached rat hepatocytes to predict hepatic clearance for poorly permeable compounds

Huang, Liyue, Chen, April, Roberts, John, Janosky, Brett, Be, Xuhai, Berry, Loren, Lin, Min-Hwa Jasmine

Journal:

Year:

2012

Language:

english

File:

PDF, 766 KB

english, 2012

10

Effects of silver nanoparticles on rat hepatic cytochrome P450 enzyme activity

Kulthong, Kornphimol, Maniratanachote, Rawiwan, Kobayashi, Yuki, Fukami, Tatsuki, Yokoi, Tsuyoshi

Journal:

Year:

2012

Language:

english

File:

PDF, 945 KB

english, 2012

11

A quantitative approach to hepatic clearance prediction of metabolism by aldehyde oxidase using custom pooled hepatocytes

Akabane, Takafumi, Gerst, Nicolas, Masters, Jeffrey N., Tamura, Kouichi

Journal:

Year:

2012

Language:

english

File:

PDF, 947 KB

english, 2012

12

Extensive intestinal glucuronidation of raloxifene in vivo in pigs and impact for oral drug delivery

Thörn, Helena Anna, Yasin, Mohammed, Dickinson, Paul Alfred, Lennernäs, Hans

Journal:

Year:

2012

Language:

english

File:

PDF, 1.13 MB

english, 2012

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