Volume 43; Issue 10

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Xenobiotica
Volume 43; Issue 10

Xenobiotica

Volume 43; Issue 10

1

A membrane vesicle-based assay to enable prediction of human biliary excretion

Colombo, Federico, Poirier, Hugo, Rioux, Nathalie, Montecillo, Maria Arias, Duan, Jianmin, Ribadeneira, Maria D.

Journal:

Year:

2013

Language:

english

File:

PDF, 227 KB

english, 2013

2

Comparative pharmacokinetics of N ω -hydroxy-nor-L-arginine, an arginase inhibitor, after single-dose intravenous, intraperitoneal and intratracheal administration to brown Norway rats

Havlinova, Zuzana, Babicova, Andrea, Hroch, Milos, Chladek, Jaroslav

Journal:

Year:

2013

Language:

english

File:

PDF, 422 KB

english, 2013

3

Dissecting the relative contribution of OATP1B1-mediated uptake of xenobiotics into human hepatocytes using siRNA

Williamson, B., Soars, A. C., Owen, A., White, P., Riley, R. J., Soars, M. G.

Journal:

Year:

2013

Language:

english

File:

PDF, 546 KB

english, 2013

4

Correlation-based prediction of tissue-to-plasma partition coefficients using readily available input parameters

Yun, Y. E., Edginton, A. N.

Journal:

Year:

2013

Language:

english

File:

PDF, 318 KB

english, 2013

5

Effects of 17α-ethynylestradiol-induced cholestasis on the pharmacokinetics of doxorubicin in rats: reduced biliary excretion and hepatic metabolism of doxorubicin

Choi, Young Hee, Lee, Yu Kyung, Lee, Myung Gull

Journal:

Year:

2013

Language:

english

File:

PDF, 226 KB

english, 2013

6

Injection of ropivacaine into the subarachnoid changes the ultrastructure and proteome of the rat spinal cord

Li, Lin, Zhang, Tiezheng, Diao, Yugang, Wang, Junke

Journal:

Year:

2013

Language:

english

File:

PDF, 1.32 MB

english, 2013

7

Simultaneous determination by LC-MS/MS of 25-methoxydammarane-3β,12β,20-triol epimers and active metabolites in rat plasma after intravenous administration

Shi, Cai-Hong, Zhang, Xiangrong, Suo, Hao, Yin, Tian, Xu, Haiyan, Yuan, Bo, Zhao, Yuqing

Journal:

Year:

2013

Language:

english

File:

PDF, 585 KB

english, 2013

8

Effect of food intake on the pharmacokinetics of sarpogrelate and its active metabolite following oral administration to beagle dogs

Baek, In-Hwan, Lee, Byung-Yo, Kim, Min-Soo, Kwon, Kwang-Il

Journal:

Year:

2013

Language:

english

File:

PDF, 526 KB

english, 2013

9

The pre-clinical absorption, distribution, metabolism and excretion properties of IPI-926, an orally bioavailable antagonist of the hedgehog signal transduction pathway

Smith, Sherri, Hoyt, Jennifer, Whitebread, Nigel, Manna, Joseph, Peluso, Marisa, Faia, Kerrie, Campbell, Veronica, Tremblay, Martin, Nair, Somarajan, Grogan, Michael, Castro, Alfredo, Campbell, Matthe

Journal:

Year:

2013

Language:

english

File:

PDF, 651 KB

english, 2013

10

A high throughput assay for the glucuronidation of 7-hydroxy-4-trifluoromethylcoumarin by recombinant human UDP-glucuronosyltransferases and liver microsomes

Rahikainen, Tuomas, Häkkinen, Merja R., Finel, Moshe, Pasanen, Markku, Juvonen, Risto O.

Journal:

Year:

2013

Language:

english

File:

PDF, 1022 KB

english, 2013

11

Assessment of a pharmacokinetic and pharmacodynamic interaction between simvastatin and Ginkgo biloba extracts in healthy subjects

Dai, Ling-Ling, Fan, Lan, Wu, Hui-Zi, Tan, Zhi-Rong, Chen, Yao, Peng, Xiang-Dong, Shen, Min-Xue, Yang, Guo-Ping, Zhou, Hong-Hao

Journal:

Year:

2013

Language:

english

File:

PDF, 270 KB

english, 2013

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