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Volume 44; Issue 2
Main
Xenobiotica
Volume 44; Issue 2
Xenobiotica
Volume 44; Issue 2
1
Chimeric rodents with humanized liver: bridging the preclinical/clinical trial gap in ADME/toxicity studies
Foster, John R.
,
Lund, Garry
,
Sapelnikova, Svetlana
,
Tyrrell, D. Lorne
,
Kneteman, Norman M.
Journal:
Xenobiotica
Year:
2014
Language:
english
File:
PDF, 348 KB
Your tags:
english, 2014
2
Current status of prediction of drug disposition and toxicity in humans using chimeric mice with humanized liver
Kitamura, Shigeyuki
,
Sugihara, Kazumi
Journal:
Xenobiotica
Year:
2014
Language:
english
File:
PDF, 1.06 MB
Your tags:
english, 2014
3
Knockout and humanized mice as suitable tools to identify enzymes metabolizing the human carcinogen aristolochic acid
Stiborová, Marie
,
Frei, Eva
,
Arlt, Volker M.
,
Schmeiser, Heinz H.
Journal:
Xenobiotica
Year:
2014
Language:
english
File:
PDF, 478 KB
Your tags:
english, 2014
4
Genetically humanized mouse models of drug metabolizing enzymes and transporters and their applications
Scheer, Nico
,
Wolf, C. Roland
Journal:
Xenobiotica
Year:
2014
Language:
english
File:
PDF, 578 KB
Your tags:
english, 2014
5
Troglitazone metabolism and transporter effects in chimeric mice: a comparison between chimeric humanized and chimeric murinized FRG mice
Samuelsson, Kristin
,
Pickup, Kathryn
,
Sarda, Sunil
,
Foster, John R.
,
Randall, Kevin
,
Abrahamsson, Anna
,
Jacobsen, Matt
,
Weidolf, Lars
,
Wilson, Ian
Journal:
Xenobiotica
Year:
2014
Language:
english
File:
PDF, 1.07 MB
Your tags:
english, 2014
6
The metabolic fate of [ 14 C]-fenclozic acid in the hepatic reductase null (HRN) mouse
Pickup, Kathryn
,
Wills, Jonathan
,
Rodrigues, Alison
,
Jones, Huw B.
,
Page, Chris
,
Martin, Scott
,
Sarda, Sunil
,
Wilson, Ian
Journal:
Xenobiotica
Year:
2014
Language:
english
File:
PDF, 461 KB
Your tags:
english, 2014
7
The phoenix rises: a new science of in vivo drug metabolism
Samuelsson, Kristin
,
Wilson, Ian D.
Journal:
Xenobiotica
Year:
2014
Language:
english
File:
PDF, 92 KB
Your tags:
english, 2014
8
The human hepatic cell line HepaRG as a possible cell source for the generation of humanized liver TK-NOG mice
Higuchi, Yuichiro
,
Kawai, Kenji
,
Yamazaki, Hiroshi
,
Nakamura, Masato
,
Bree, Françoise
,
Guguen-Guillouzo, Christiane
,
Suemizu, Hiroshi
Journal:
Xenobiotica
Year:
2014
Language:
english
File:
PDF, 1.62 MB
Your tags:
english, 2014
9
Endogenous and xenobiotic metabolite profiling of liver extracts from SCID and chimeric humanized mice following repeated oral administration of troglitazone
Barnes, Alan J.
,
Baker, David R.
,
Hobby, Kirsten
,
Ashton, Simon
,
Michopoulos, Filippos
,
Spagou, Konstantina
,
Loftus, Neil J.
,
Wilson, Ian D.
Journal:
Xenobiotica
Year:
2014
Language:
english
File:
PDF, 1.75 MB
Your tags:
english, 2014
10
In vitro and in vivo metabolism of a novel chymase inhibitor, SUN13834, and the predictability of human metabolism using mice with humanized liver
Igawa, Yoshiyuki
,
Fujitani, Tomomichi
,
Shah, Bharti
,
Oo, Charles
,
Kanai, Yasushi
Journal:
Xenobiotica
Year:
2014
Language:
english
File:
PDF, 616 KB
Your tags:
english, 2014
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