Volume 44; Issue 8

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Xenobiotica
Volume 44; Issue 8

Xenobiotica

Volume 44; Issue 8

1

Contribution of cytochrome P450 and UDT-glucuronosyltransferase to the metabolism of drugs containing carboxylic acid groups: risk assessment of acylglucuronides using human hepatocytes

Jinno, Norimasa, Tagashira, Mizuka, Tsurui, Kazuyuki, Yamada, Shizuo

Journal:

Year:

2014

Language:

english

File:

PDF, 299 KB

english, 2014

2

Gradient elution liquid chromatography mass spectrometry determination of acetylcorynoline in rat plasma and its application to a pharmacokinetic study

Wen, Congcong, Cai, Jinzhang, Lin, Chongliang, Ma, Jianshe, Wang, Xianqin

Journal:

Year:

2014

Language:

english

File:

PDF, 456 KB

english, 2014

3

Identification of glucuronidation and biliary excretion as the main mechanisms for gossypol clearance: in vivo and in vitro evidence

Liu, Hongming, Sun, Hua, Lu, Danyi, Zhang, Yuchen, Zhang, Xingwang, Ma, Zhiguo, Wu, Baojian

Journal:

Year:

2014

Language:

english

File:

PDF, 1.24 MB

english, 2014

4

P-glycoprotein (P-gp)-mediated efflux limits intestinal absorption of the Hsp90 inhibitor SNX-2112 in rats

Liu, Hongming, Sun, Hua, Wu, Zhufeng, Zhang, Xingwang, Wu, Baojian

Journal:

Year:

2014

Language:

english

File:

PDF, 277 KB

english, 2014

5

Acyclic nucleoside phosphonates: a study on cytochrome P450 gene expression

Nekvindova, Jana, Contreras, Juan Antonio, Juvan, Peter, Fon Tacer, Klementina, Anzenbacher, Pavel, Zidek, Zdenek, Kopecna Zapletalova, Michaela, Rozman, Damjana, Anzenbacherova, Eva

Journal:

Year:

2014

Language:

english

File:

PDF, 423 KB

english, 2014

6

Investigation on pharmacokinetics, tissue distribution and excretion of a novel platinum anticancer agent in rats by Inductively Coupled Plasma Mass Spectrometry (ICP-MS)

Zhao, Jie, Wen, Yanli, Zhang, Wei, Zhao, Di, Fan, Ali, Zhang, Yongjie, Deng, Shuhua, Wang, Xin, Liu, Qingwang, Lu, Yang, Wang, Zhimei, Gou, Shaohua, Chen, Xijing

Journal:

Year:

2014

Language:

english

File:

PDF, 294 KB

english, 2014

7

Structure identification and elucidation of mosapride metabolites in human urine, feces and plasma by ultra performance liquid chromatography-tandem mass spectrometry method

Sun, Xiaohong, Zhao, Longshan, Niu, Lili, Qin, Feng, Lu, Xiumei, Xiong, Zhili, Li, Famei

Journal:

Year:

2014

Language:

english

File:

PDF, 1.01 MB

english, 2014

8

Effect of commonly used organic solvents on Aldehyde oxidase-mediated Vanillin, Phthalazine and Methotrexate oxidation in human, rat and mouse liver subcellular fractions

Behera, Dayanidhi, Pattem, Rambabu, Gudi, Girish

Journal:

Year:

2014

Language:

english

File:

PDF, 1.25 MB

english, 2014

9

Identification of saturated and unsaturated fatty acids released during microsomal incubations

Bushee, Jennifer L., Liang, Guiqing, Dunne, Christine E., Harriman, Shawn P., Argikar, Upendra A.

Journal:

Year:

2014

Language:

english

File:

PDF, 575 KB

english, 2014

10

Glucuronidation of aurantio-obtusin: identification of human UDP-glucuronosyltransferases and species differences

Mi, Bao-Li, Sun, Qi, Qu, Yan-Qing, Gao, Xiao-Xu, Yu, Zhen-Wen, Ge, Guang-Bo, Cai, Shan-Shan, Zhang, Jie, Zheng, Yan-Chao, Zhang, Zhen-Qiu

Journal:

Year:

2014

Language:

english

File:

PDF, 359 KB

english, 2014

11

Disposition of fragrance ingredient [ 14 C]1-(1,2,3,4,5,6,7,8-octahydro-2,3,8,8-tetramethyl-2-naphthalenyl)ethanone in male Fisher rats following oral administration and dermal application

Waidyanatha, Suramya, Ryan, Kristen

Journal:

Year:

2014

Language:

english

File:

PDF, 271 KB

english, 2014

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