Volume 45; Issue 6

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Xenobiotica
Volume 45; Issue 6

Xenobiotica

Volume 45; Issue 6

1

The mechanism of rapamycin in the intervention of paraquat-induced acute lung injury in rats

Chen, Da, Jiao, Guangyu, Ma, Tao, Liu, Xiaowei, Yang, Chen, Liu, Zhi

Journal:

Year:

2015

Language:

english

File:

PDF, 581 KB

english, 2015

2

Effects of Guanxinning injection on rat cytochrome P450 isoforms activities in vivo and in vitro

Yu, Yue, Liu, Yan, Li, Qian, Sun, Jiahui, Lin, Haiou, Liu, Gaofeng

Journal:

Year:

2015

Language:

english

File:

PDF, 512 KB

english, 2015

3

In vitro metabolism of a novel JNK inhibitor tanzisertib: interspecies differences in oxido-reduction and characterization of enzymes involved in metabolism

Atsriku, Christian, Hoffmann, Matthew, Moghaddam, Mehran, Kumar, Gondi, Surapaneni, Sekhar

Journal:

Year:

2015

Language:

english

File:

PDF, 1.41 MB

english, 2015

4

In vitro/in vivo investigations to examine the gender differences in the pharmacokinetics of novel oral Janus kinase (JAK) inhibitor ASP015K and sulfate metabolite M2 in rats

Oda, Kazuo, Nakada, Naoyuki, Nagasaka, Yasuhisa

Journal:

Year:

2015

Language:

english

File:

PDF, 542 KB

english, 2015

5

Characterization of bovine phenol sulfotransferases: evidence of a major role for SULT1B1 in the liver

Choughule, Kanika V., Locuson, Charles W., Coughtrie, Michael W. H.

Journal:

Year:

2015

Language:

english

File:

PDF, 484 KB

english, 2015

6

Differences in the glucuronidation of bisphenols F and S between two homologous human UGT enzymes, 1A9 and 1A10

Gramec Skledar, Darja, Troberg, Johanna, Lavdas, Jason, Peterlin Mašič, Lucija, Finel, Moshe

Journal:

Year:

2015

Language:

english

File:

PDF, 437 KB

english, 2015

7

Identification and functional characterization of novel feline cytochrome P450 2A

Okamatsu, Gaku, Komatsu, Tetsuya, Kubota, Akira, Onaga, Takenori, Uchide, Tsuyoshi, Endo, Daiji, Kirisawa, Rikio, Yin, Guojun, Inoue, Hiroki, Kitazawa, Takio, Uno, Yasuhiro, Teraoka, Hiroki

Journal:

Year:

2015

Language:

english

File:

PDF, 519 KB

english, 2015

8

Pharmacokinetics and tissue distribution study of novel potent antiplatelet agent S007-867 in mice using HPLC-MS/MS

Chandasana, Hardik, Chhonker, Yashpal S., Prasad, Yarra Durga, Laxman, Tulsankar Sachin, Anil Kumar, K. S., Dikshit, Dinesh K., Bhatta, Rabi S.

Journal:

Year:

2015

Language:

english

File:

PDF, 345 KB

english, 2015

9

Differential role of P-glycoprotein and breast cancer resistance protein in drug distribution into brain, CSF and peripheral nerve tissues in rats

Huang, Liyue, Li, Xingwen, Roberts, Jonathan, Janosky, Brett, Lin, Min-Hwa Jasmine

Journal:

Year:

2015

Language:

english

File:

PDF, 322 KB

english, 2015

10

Biotransformation and mass balance of the SGLT2 inhibitor empagliflozin in healthy volunteers

Chen, Lin-Zhi, Jungnik, Arvid, Mao, Yanping, Philip, Elsy, Sharp, Dale, Unseld, Anna, Seman, Leo, Woerle, Hans-Jürgen, Macha, Sreeraj

Journal:

Year:

2015

Language:

english

File:

PDF, 679 KB

english, 2015

11

Key determinants of the circulatory exposure of organic anions: differences in hepatic uptake between multidrug resistance-associated protein 2 (Mrp2)-deficient rats and wild-type rats

Kosaka, Keigo, Watanabe, Tomoko, Susukida, Takeshi, Aoki, Shigeki, Sekine, Shuichi, Kume, Toshiyuki, Ito, Kousei

Journal:

Year:

2015

Language:

english

File:

PDF, 878 KB

english, 2015

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