Volume 45; Issue 8

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Xenobiotica
Volume 45; Issue 8

Xenobiotica

Volume 45; Issue 8

1

Pharmacokinetics, pharmacodynamics and food effect of LB30870, a novel direct thrombin inhibitor, after single oral doses in healthy men

Kim, John, Lee, Sung-Hack, Boyce, Malcolm, Warrington, Steve, Cho, Kwan Hyung, Yoon, Suk Kyoon, Park, Hee Dong, Kim, Aeri

Journal:

Year:

2015

Language:

english

File:

PDF, 406 KB

english, 2015

2

Combined effect of rifampicin-induced P-glycoprotein expression and lipopolysaccharide-induced intestinal sepsis on the effective permeability and pharmacokinetics of an anti-malarial candidate CDRI 97/78 in rats

Singh, Yeshwant, Hidau, Mahendra Kumar, Krishna, Jampala, Singh, Shio Kumar

Journal:

Year:

2015

Language:

english

File:

PDF, 611 KB

english, 2015

3

Pharmacokinetics and metabolism of AMG 232, a novel orally bioavailable inhibitor of the MDM2–p53 interaction, in rats, dogs and monkeys: in vitro–in vivo correlation

Ye, Qiuping, Jiang, Min, Huang, Wotang T., Ling, Yun, Olson, Steven H., Sun, Daqing, Xu, Guifen, Yan, Xuelei, Wong, Bradley K., Jin, Lixia

Journal:

Year:

2015

Language:

english

File:

PDF, 602 KB

english, 2015

4

Transport of trans- tiliroside (kaempferol-3- β -D-(6″- p- coumaroyl-glucopyranoside) and related flavonoids across Caco-2 cells, as a model of absorption and metabolism in the small intestine

Luo, Zijun, Morgan, Michael R. A., Day, Andrea J.

Journal:

Year:

2015

Language:

english

File:

PDF, 439 KB

english, 2015

5

In vitro and in vivo metabolism of CHF 6001, a selective phosphodiesterase (PDE4) inhibitor

Cenacchi, Valentina, Battaglia, Rosangela, Cinato, Flavio, Riccardi, Benedetta, Spinabelli, Daniele, Brogin, Giandomenico, Puccini, Paola, Pezzetta, Daniele

Journal:

Year:

2015

Language:

english

File:

PDF, 1.21 MB

english, 2015

6

In vitro effects of standardized extract of Bacopa monniera and its five individual active constituents on human P-glycoprotein activity

Singh, Rajbir, Rachumallu, Ramakrishna, Bhateria, Manisha, Panduri, Jagadeesh, Bhatta, Rabi Sankar

Journal:

Year:

2015

Language:

english

File:

PDF, 481 KB

english, 2015

7

Establishment of pharmacophore and VolSurf models to predict the substrates of UDP-glucuronosyltransferase1A3

Wu, Zhufeng, Zhang, Xingwang, Ma, Zhiguo, Wu, Baojian

Journal:

Year:

2015

Language:

english

File:

PDF, 621 KB

english, 2015

8

The metabolism of 4-bromoaniline in the bile-cannulated rat: application of ICPMS ( 79/81 Br), HPLC-ICPMS & HPLC-oaTOFMS

Duckett, Catherine, McCullagh, Michael, Smith, Christopher, Wilson, Ian D

Journal:

Year:

2015

Language:

english

File:

PDF, 1.13 MB

english, 2015

9

Metabolic disposition of the anti-cancer agent [ 14 C]laromustine in male rats

Nassar, Ala F., Wisnewski, Adam, King, Ivan

Journal:

Year:

2015

Language:

english

File:

PDF, 1.18 MB

english, 2015