Volume 8; Issue 4

Pharmacology Research & Perspectives

Volume 8; Issue 4

1

A multicenter, phase I, pharmacokinetic study of osimertinib in cancer patients with normal renal function or severe renal impairment

Vishwanathan, Karthick, SanchezâSimon, Inmaculada, Keam, Bhumsuk, Penel, Nicolas, MiguelâLuken, Maria, Weilert, Doris, Mills, Andrew, Marotti, Marcelo, Johnson, Martin, Ravaud, Alain

Journal:

Pharmacology Research & Perspectives

Year:

2020

File:

PDF, 1.51 MB

2020

2

Introducing variability in targeting the microtubules: Review of current mechanisms and future directions in colchicine therapy

Forkosh, Esther, Kenig, Ariel, Ilan, Yaron

Journal:

Pharmacology Research & Perspectives

Year:

2020

File:

PDF, 1.60 MB

2020

3

The affinity and selectivity of Î±âadrenoceptor antagonists, antidepressants, and antipsychotics for the human Î±1A, Î±1B, and Î±1Dâadrenoceptors

Proudman, Richard G. W., Pupo, Andre S., Baker, Jillian G.

Journal:

Pharmacology Research & Perspectives

Year:

2020

File:

PDF, 2.91 MB

2020

4

The endothelin receptor antagonist macitentan for the treatment of pulmonary arterial hypertension: A crossâspecies comparison of its cytochrome P450 induction pattern

Treiber, Alexander, Delahaye, Stephane, Seeland, Swen, Gnerre, Carmela

Journal:

Pharmacology Research & Perspectives

Year:

2020

File:

PDF, 2.24 MB

2020

5

Buying time: Drug repurposing to treat the host in COVIDâ19H

Martin, Jennifer H., Clark, Julian, Head, Richard

Journal:

Pharmacology Research & Perspectives

Year:

2020

File:

PDF, 584 KB

2020

6

Characterization of TâDM1âresistant breast cancer cells

Sauveur, Juliette, Conilh, Louise, Beaumel, Sabine, Chettab, Kamel, Jordheim, LarsâPetter, Matera, EvaâLaure, Dumontet, Charles

Journal:

Pharmacology Research & Perspectives

Year:

2020

File:

PDF, 1.97 MB

2020

7

Mechanistic insights into antiretroviral drugâinduced liver injury

Pillaye, Jamie N., Marakalala, Mohlopheni J., Khumalo, Nonhlanhla, Spearman, Wendy, Ndlovu, Hlumani

Journal:

Pharmacology Research & Perspectives

Year:

2020

File:

PDF, 1.32 MB

2020

8

Endotheliumâderived dopamine modulates EFSâinduced contractions of human umbilical vessels

BrittoâJÃºnior, JosÃ©, Pinheiro, David H. A., Justo, Alberto F. O., Figueiredo Murari, Guilherme M., Campos, Rafael, Mariano, Fernanda V., Souza, ValÃ©ria B., Schenka, AndrÃ© A., MÃ³nica, Fabiola Z.

Journal:

Pharmacology Research & Perspectives

Year:

2020

File:

PDF, 2.78 MB

2020

9

The reninâangiotensinâaldosterone system: Role in pathogenesis and potential therapeutic target in COVIDâ19

Braga, CÃ¡ssia L., SilvaâAguiar, Rodrigo P., Battaglini, Denise, Peruchetti, Diogo B., Robba, Chiara, Pelosi, Paolo, Rocco, Patricia R. M., CarusoâNeves, Celso, Silva, Pedro L.

Journal:

Pharmacology Research & Perspectives

Year:

2020

File:

PDF, 1.31 MB

2020

10

A simple open source bioinformatic methodology for initial exploration of GPCR ligandsâ agonistic/antagonistic properties

Panagiotopoulos, Athanasios A., Papachristofi, Christina, Kalyvianaki, Konstantina, Malamos, Panagiotis, Theodoropoulos, Panayiotis A., Notas, George, Calogeropoulou, Theodora, Castanas, Elias, Kampa,

Journal:

Pharmacology Research & Perspectives

Year:

2020

File:

PDF, 1.83 MB

2020

11

The efficacy of steroids in reducing morbidity and mortality from extreme hyperthermia and heatstrokeâA systematic review

Walter, Edward, Gibson, Oliver R.

Journal:

Pharmacology Research & Perspectives

Year:

2020

File:

PDF, 1.66 MB

2020

12

Comparative risk of cardiac arrhythmias associated with acetylcholinesterase inhibitors used in treatment of dementias â A narrative review

Huang, Yichang, Alsabbagh, Mhd. Wasem

Journal:

Pharmacology Research & Perspectives

Year:

2020

File:

PDF, 1.57 MB

2020

13

Polypharmacy, potentially serious clinically relevant drugâdrug interactions, and inappropriate medicines in elderly people with type 2 diabetes and their impact on quality of life

ALâMusawe, Labib, Torre, Carla, Guerreiro, Jose Pedro, Rodrigues, Antonio Teixeira, Raposo, Joao Filipe, MotaâFilipe, Helder, Martins, Ana Paula

Journal:

Pharmacology Research & Perspectives

Year:

2020

File:

PDF, 1.39 MB

2020

14

Comparison between esomeprazole 20 mg Vs 40 mg as stress ulcer prophylaxis (SUP) in critically ill patients: A retrospective cohort study

Al Sulaiman, Khalid, Al Aamer, Kholoud, Al Harthi, Alaa, Jaser, Saud, Al Anazi, Abdulrahman, Al Subaie, Sultan, Vishwakarma, Ramesh

Journal:

Pharmacology Research & Perspectives

Year:

2020

File:

PDF, 1.05 MB

2020

15

Hypothesis: Pentoxifylline is a potential cytokine modulator therapeutic in COVIDâ19 patients

Hendry, Bruce M., Stafford, Nina, Arnold, Ahran D., Sangwaiya, Arvind, Manglam, Vijay, Rosen, Stuart D., Arnold, Jayantha

Journal:

Pharmacology Research & Perspectives

Year:

2020

File:

PDF, 798 KB

2020

16

A pharmacistâmanaged dosing algorithm for darbepoetin alfa and iron sucrose in hemodialysis patients: A randomized, controlled trial

Oever, Francisca Johanna, HeetmanâMeijer, Carolien F. M., Birnie, Erwin, Vasbinder, Erwin C., Swart, Eleonora L., Schrama, Yvonne C.

Journal:

Pharmacology Research & Perspectives

Year:

2020

File:

PDF, 1.38 MB

2020

17

Acute antioxidant and cytoprotective effects of sulforaphane in brain endothelial cells and astrocytes during inflammation and excitotoxicity

Liu, Jianxiong, Chandaka, Giri K., Zhang, Rong, Parfenova, Helena

Journal:

Pharmacology Research & Perspectives

Year:

2020

File:

PDF, 2.00 MB

2020

18

Ascorbate sensitizes human osteosarcoma cells to the cytostatic effects of cisplatin

Oka, Naohiro, Komuro, Akiyoshi, Amano, Hisayuki, Dash, Suman, Honda, Masahiko, Ota, Kazushige, Nishimura, Shunji, Ueda, Takeshi, Akagi, Masao, Okada, Hitoshi

Journal:

Pharmacology Research & Perspectives

Year:

2020

File:

PDF, 2.84 MB

2020

19

In vitro and in vivo human metabolism and pharmacokinetics of Sâ and Râpraziquantel

Kapungu, Nyasha Nicole, Li, Xueqing, Nhachi, Charles, Masimirembwa, Collen, Thelingwani, Roslyn Stella

Journal:

Pharmacology Research & Perspectives

Year:

2020

File:

PDF, 2.29 MB

2020

20

No relation between docetaxel administration route and highâgrade diarrhea incidence

Hendrikx, Jeroen J. M. A., Stuurman, Frederik E., Song, JiâYing, Weger, Vincent A., Lagas, Jurjen S., Rosing, Hilde, Beijnen, Jos H., Schinkel, Alfred H., Schellens, Jan H. M., Marchetti, Serena

Journal:

Pharmacology Research & Perspectives

Year:

2020

File:

PDF, 2.60 MB

2020

21

Effects of RAGE inhibition on the progression of the disease in hSOD1 G93A ALS mice

Liu, Liping, Killoy, Kelby M., Vargas, Marcelo R., Yamamoto, Yasuhiko, Pehar, Mariana

Journal:

Pharmacology Research & Perspectives

Year:

2020

File:

PDF, 3.00 MB

2020

22

ZYBT1, a potent, irreversible Brutonâs Tyrosine Kinase (BTK) inhibitor that inhibits the C481S BTK with profound efficacy against arthritis and cancer

Ghoshdastidar, Krishnarup, Patel, Hoshang, Bhayani, Hitesh, Patel, Ankit, Thakkar, Kinjal, Patel, Dinesh, Sharma, Manoranjan, Singh, Jaideep, Mohapatra, Jogeswar, Chatterjee, Abhijit, Patel, Dipam, Ba

Journal:

Pharmacology Research & Perspectives

Year:

2020

File:

PDF, 2.98 MB

2020

23

In vitro metabolic profile and drugâdrug interaction assessment of secnidazole, a highâdose 5ânitroimidazole antibiotic for the treatment of bacterial vaginosis

Pentikis, Helen S., Adetoro, Nikki, Kaufman, Gregory

Journal:

Pharmacology Research & Perspectives

Year:

2020

File:

PDF, 1.32 MB

2020

24

Reciprocal interference between the NRF2 and LPS signaling pathways on the immuneâmetabolic phenotype of peritoneal macrophages

Mornata, Federica, Pepe, Giovanna, Sfogliarini, Chiara, Brunialti, Electra, Rovati, Gianenrico, Locati, Massimo, Maggi, Adriana, Vegeto, Elisabetta

Journal:

Pharmacology Research & Perspectives

Year:

2020

File:

PDF, 1.53 MB

2020

25

In vivo and in silico characterization of apocynin in reducing organ oxidative stress: A pharmacokinetic and pharmacodynamic study

Liu, Fangfei, Fan, Lampson M., Michael, Nicholas, Li, JianâMei

Journal:

Pharmacology Research & Perspectives

Year:

2020

File:

PDF, 2.61 MB

2020

26

Nuances to precision dosing strategies of targeted cancer medicines

Hopkins, Ashley M., Menz, Bradley D., Wiese, Michael D., Kichenadasse, Ganessan, Gurney, Howard, McKinnon, Ross A., Rowland, Andrew, Sorich, Michael J.

Journal:

Pharmacology Research & Perspectives

Year:

2020

File:

PDF, 1.60 MB

2020

27

Issue Information

Journal:

Pharmacology Research & Perspectives

Year:

2020

File:

PDF, 1.23 MB

2020

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