Volume 6; Issue 8

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Bioanalysis
Volume 6; Issue 8

Bioanalysis

Volume 6; Issue 8

1

Matrix interference in ligand-binding assays: challenge or solution?

DeSilva, Binodh, Garofolo, Fabio

Journal:

Year:

2014

Language:

english

File:

PDF, 667 KB

english, 2014

2

Measuring biotherapeutics with endogenous counterparts and pre-existing antibodies: an interferon case study

Myler, Heather, Felix, Tonya, Zhu, Jie, Hruska, Matt, Piccoli, Steven P

Journal:

Year:

2014

Language:

english

File:

PDF, 1.27 MB

english, 2014

3

Protein-based matrix interferences in ligand-binding assays

Gorovits, Boris, McNally, Jim, Fiorotti, Corinna, Leung, Sheldon

Journal:

Year:

2014

Language:

english

File:

PDF, 719 KB

english, 2014

4

Due diligence in the characterization of matrix effects in a total IL-13 Singulex™ method

Fraser, Stephanie, Soderstrom, Catherine

Journal:

Year:

2014

Language:

english

File:

PDF, 1008 KB

english, 2014

5

Addressing matrix effects in ligand-binding assays through the use of new reagents and technology

Chilewski, Shannon D, Mora, Johanna R, Gleason, Carol, DeSilva, Binodh

Journal:

Year:

2014

Language:

english

File:

PDF, 1.31 MB

english, 2014

6

Matrix effect in ligand-binding assay: the importance of evaluating emerging technologies

Crisino, Rebecca M, Luo, Linlin, Geist, Brian, Zoghbi, Jad, Spriggs, Franklin

Journal:

Year:

2014

Language:

english

File:

PDF, 716 KB

english, 2014

7

An ultra-sensitive clinical biomarker assay: quantitation of thymus and activation-regulated chemokine in human plasma

Zhao, Xuemei, Delgado, Liliana, Weiner, Russell, Laterza, Omar F

Journal:

Year:

2014

Language:

english

File:

PDF, 871 KB

english, 2014

8

Orthogonal tools to help determine the required selectivity of ligand-binding assays in drug development

Journal:

Year:

2014

Language:

english

File:

PDF, 726 KB

english, 2014

9

Evaluating the impact of matrix effects on biomarker assay sensitivity

Thway, Theingi, Salimi-Moosavi, Hossein

Journal:

Year:

2014

Language:

english

File:

PDF, 1.38 MB

english, 2014

10

Resolution of matrix interference: quantitative and quasi-quantitative ligand-binding assays case studies

Spriggs, Franklin P, Duriga, Nicole, Rathi, Alok, Qu, Qiang

Journal:

Year:

2014

Language:

english

File:

PDF, 1.37 MB

english, 2014

11

Challenges in selectivity, specificity and quantitation range of ligand-binding assays: case studies using a microfluidics platform

Yang, Tong-Yuan, Uhlinger, David J, Ayers, Stephen A, O’Hara, Denise M, Joyce, Alison P

Journal:

Year:

2014

Language:

english

File:

PDF, 1.11 MB

english, 2014

12

Are matrix effects the Achilles heel in the bioanalysis of biotherapeutics by ligand-binding assays?

Wang, Qingqing, Ma, Mark

Journal:

Year:

2014

Language:

english

File:

PDF, 865 KB

english, 2014

13

Strategic approaches for assessment and minimization of matrix effect in ligand-binding assays

Shih, Judy Y, Patel, Vimal, Ma, Mark

Journal:

Year:

2014

Language:

english

File:

PDF, 1.36 MB

english, 2014

14

News & Analysis

Journal:

Year:

2014

Language:

english

File:

PDF, 578 KB

english, 2014