Volume 409; Issue 2

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Biochemical Journal
Volume 409; Issue 2

Biochemical Journal

Volume 409; Issue 2

1

Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors

Khan, Nagma, Jeffers, Michael, Kumar, Sampath, Hackett, Craig, Boldog, Ferenc, Khramtsov, Nicholai, Qian, Xiaozhong, Mills, Evan, Berghs, Stanny C., Carey, Nessa, Finn, Paul W., Collins, Laura S., Tum

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 520 KB

english, 2008

2

SPAK and OSR1: STE20 kinases involved in the regulation of ion homoeostasis and volume control in mammalian cells

Delpire, Eric, Gagnon, Kenneth B. E.

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 868 KB

english, 2008

3

The histidine phosphatase superfamily: structure and function

Rigden, Daniel J.

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 1.42 MB

english, 2008

4

The lectin-like oxidized low-density-lipoprotein receptor: a pro-inflammatory factor in vascular disease

Dunn, Sarah, Vohra, Ravinder S., Murphy, Jane E., Homer-Vanniasinkam, Shervanthi, Walker, John H., Ponnambalam, Sreenivasan

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 1.19 MB

english, 2008

5

Effects of oncogenic p110α subunit mutations on the lipid kinase activity of phosphoinositide 3-kinase

Carson, Jeffrey D., Van Aller, Glenn, Lehr, Ruth, Sinnamon, Robert H., Kirkpatrick, Robert B., Auger, Kurt R., Dhanak, Dashyant, Copeland, Robert A., Gontarek, Richard R., Tummino, Peter J., Luo, Luso

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 317 KB

english, 2008

6

A novel zinc-dependent D-serine dehydratase from Saccharomyces cerevisiae

Ito, Tomokazu, Hemmi, Hisashi, Kataoka, Kunishige, Mukai, Yukio, Yoshimura, Tohru

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 170 KB

english, 2008

7

Glucosylated free oligosaccharides are biomarkers of endoplasmic- reticulum α-glucosidase inhibition

Alonzi, Dominic S., Neville, David C. A., Lachmann, Robin H., Dwek, Raymond A., Butters, Terry D.

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 186 KB

english, 2008

8

The role of loop and β-turn residues as structural and functional determinants for the lipoyl domain from the Escherichia coli 2-oxoglutarate dehydrogenase complex

Jones, D. Dafydd, Perham, Richard N.

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 617 KB

english, 2008

9

Chelator-facilitated removal of iron from transferrin: relevance to combined chelation therapy

Devanur, Lakshmi D., Evans, Robert W., Evans, Patricia J., Hider, Robert C.

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 247 KB

english, 2008

10

Novel molecules for intra-oral delivery of antimicrobials to prevent and treat oral infectious diseases

Raj, Periathamby Antony, Rajkumar, Latha, Dentino, Andrew R.

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 172 KB

english, 2008

11

Mammalian GPI-anchored proteins require p24 proteins for their efficient transport from the ER to the plasma membrane

Takida, Satoshi, Maeda, Yusuke, Kinoshita, Taroh

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 787 KB

english, 2008

12

Polyamines modulate the subcellular localization of RNA-binding protein HuR through AMP-activated protein kinase-regulated phosphorylation and acetylation of importin α1

Zou, Tongtong, Liu, Lan, Rao, Jaladanki N., Marasa, Bernard S., Chen, Jie, Xiao, Lan, Zhou, Huiping, Gorospe, Myriam, Wang, Jian-Ying

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 948 KB

english, 2008

13

Conserved substrate binding by chaperones in the bacterial periplasm and the mitochondrial intermembrane space

Alcock, Felicity H., Grossmann, J. Günter, Gentle, Ian E., Likić, Vladimir A., Lithgow, Trevor, Tokatlidis, Kostas

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 920 KB

english, 2008

14

An insight into the mechanism of inhibition of unusual bi-subunit topoisomerase I from Leishmania donovani by 3,3′-di-indolylmethane, a novel DNA topoisomerase I poison with a strong binding affinity to the enzyme

Roy, Amit, Das, Benu Brata, Ganguly, Agneyo, Bose Dasgupta, Somdeb, Khalkho, Neeta V. M., Pal, Churala, Dey, Sumit, Giri, Venkatachalam Sesha, Jaisankar, Parasuraman, Dey, Sanjit, Majumder, Hemanta K.

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 698 KB

english, 2008

15

Insights into the structural basis of the pH-dependent dimer–tetramer equilibrium through crystallographic analysis of recombinant Diocleinae lectins

Nagano, Celso S., Calvete, Juan J., Barettino, Domingo, Pérez, Alicia, Cavada, Benildo S., Sanz, Libia

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 2.04 MB

english, 2008

16

A gain-of-function mutant of Munc18-1 stimulates secretory granule recruitment and exocytosis and reveals a direct interaction of Munc18-1 with Rab3

Graham, Margaret E., Handley, Mark T. W., Barclay, Jeff W., Ciufo, Leo F., Barrow, Stephanie L., Morgan, Alan, Burgoyne, Robert D.

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 874 KB

english, 2008

17

A conserved mechanism for replication origin recognition and binding in archaea

Majerník, Alan I., Chong, James P. J.

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 304 KB

english, 2008

18

Prototype chicken galectins revisited: characterization of a third protein with distinctive hydrodynamic behaviour and expression pattern in organs of adult animals

Kaltner, Herbert, Solís, Dolores, Kopitz, Jürgen, Lensch, Martin, Lohr, Michaela, Manning, Joachim C., Mürnseer, Michael, Schnölzer, Martina, André, Sabine, Sáiz, José Luis, Gabius, Hans-Joachim

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 528 KB

english, 2008

19

Regulation of clathrin-dependent endocytosis by diacylglycerol kinase δ: importance of kinase activity and binding to AP2α

Kawasaki, Takumi, Kobayashi, Takeshi, Ueyama, Takehiko, Shirai, Yasuhito, Saito, Naoaki

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 755 KB

english, 2008

20

Molecular determinants of activation and membrane targeting of phosphoinositol 4-kinase IIβ

Jung, Gwanghyun, Wang, Jing, Wlodarski, Pawel, Barylko, Barbara, Binns, Derk D., Shu, Hongjun, Yin, Helen L., Albanesi, Joseph P.

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 681 KB

english, 2008

21

Human group III secreted phospholipase A 2 promotes neuronal outgrowth and survival

Masuda, Seiko, Yamamoto, Kei, Hirabayashi, Tetsuya, Ishikawa, Yukio, Ishii, Toshiharu, Kudo, Ichiro, Murakami, Makoto

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 1.78 MB

english, 2008

22

Activity profiling of human deSUMOylating enzymes (SENPs) with synthetic substrates suggests an unexpected specificity of two newly characterized members of the family

Drag, Marcin, Mikolajczyk, Jowita, Krishnakumar, I. M., Huang, Ziwei, Salvesen, Guy S.

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 756 KB

english, 2008

23

Trimerization of collagen IX α-chains does not require the presence of the COL1 and NC1 domains

Jäälinoja, Juha, Ylöstalo, Joni, Beckett, William, Hulmes, David J. S., Ala-Kokko, Leena

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 424 KB

english, 2008

24

Complementary regulation of TBC1D1 and AS160 by growth factors, insulin and AMPK activators

Chen, Shuai, Murphy, Jane, Toth, Rachel, Campbell, David G., Morrice, Nick A., Mackintosh, Carol

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 798 KB

english, 2008

25

The stability and aggregation of ovine prion protein associated with classical and atypical scrapie correlates with the ease of unwinding of helix-2

Fitzmaurice, Tim J., Burke, David F., Hopkins, Lee, Yang, Sujeong, Yu, Shuiliang, Sy, Man-Sun, Thackray, Alana M., Bujdoso, Raymond

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 914 KB

english, 2008

26

High rates of superoxide production in skeletal-muscle mitochondria respiring on both complex I- and complex II-linked substrates

Muller, Florian L., Liu, Yuhong, Abdul-Ghani, Muhammad A., Lustgarten, Michael S., Bhattacharya, Arunabh, Jang, Youngmok C., Van Remmen, Holly

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 301 KB

english, 2008

27

Complementary roles of SufA and IscA in the biogenesis of iron–sulfur clusters in Escherichia coli

Lu, Jianxin, Yang, Juanjuan, Tan, Guoqiang, Ding, Huangen

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 273 KB

english, 2008

28

Validation of spermidine synthase as a drug target in African trypanosomes

Taylor, Martin C., Kaur, Harparkash, Blessington, Bernard, Kelly, John M., Wilkinson, Shane R.

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 469 KB

english, 2008

29

Function of the N-terminus of zizimin1: autoinhibition and membrane targeting

Meller, Nahum, Westbrook, M. Jody, Shannon, John D., Guda, Chittibabu, Schwartz, Martin A.

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 990 KB

english, 2008

30

Amino acids 39–456 of the large subunit and 210–262 of the small subunit constitute the minimal functionally interacting fragments of the unusual heterodimeric topoisomerase IB of Leishmania

Bosedasgupta, Somdeb, Das, Benu Brata, Sengupta, Souvik, Ganguly, Agneyo, Roy, Amit, Tripathi, Gayatri, Majumder, Hemanta K.

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 1.02 MB

english, 2008

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