Volume 441; Issue 3

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Biochemical Journal
Volume 441; Issue 3

Biochemical Journal

Volume 441; Issue 3

1

A mitochondrial-targeted cyclosporin A with high binding affinity for cyclophilin D yields improved cytoprotection of cardiomyocytes

Dube, Henry, Selwood, David, Malouitre, Sylvanie, Capano, Michela, Simone, Michela I., Crompton, Martin

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 483 KB

english, 2012

2

Dynamic measurements of mitochondrial hydrogen peroxide concentration and glutathione redox state in rat pancreatic β-cells using ratiometric fluorescent proteins: confounding effects of pH with HyPer but not roGFP1

Roma, Leticia P., Duprez, Jessica, Takahashi, Hilton K., Gilon, Patrick, Wiederkehr, Andreas, Jonas, Jean‑Christophe

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 692 KB

english, 2012

3

Re-examination of the dimerization state of leucine-rich repeat kinase 2: predominance of the monomeric form

Ito, Genta, Iwatsubo, Takeshi

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 1.05 MB

english, 2012

4

Ceramide synthases at the centre of sphingolipid metabolism and biology

Mullen, Thomas D., Hannun, Yusuf A., Obeid, Lina M.

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 693 KB

english, 2012

5

Glycogen and its metabolism: some new developments and old themes

Roach, Peter J., Depaoli‑Roach, Anna A., Hurley, Thomas D., Tagliabracci, Vincent S.

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 1.95 MB

english, 2012

6

Induction of oxidative stress, lysosome activation and autophagy by nanoparticles in human brain-derived endothelial cells

Halamoda Kenzaoui, Blanka, Chapuis Bernasconi, Catherine, Guney‑Ayra, Seher, Juillerat‑Jeanneret, Lucienne

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 827 KB

english, 2012

7

Large T-antigen up-regulates K v 4.3 K + channels through Sp1, and K v 4.3 K + channels contribute to cell apoptosis and necrosis through activation of calcium/calmodulin-dependent protein kinase II

Li, Qi, Zhang, Ying, Sheng, Yue, Huo, Rong, Sun, Bo, Teng, Xue, Li, Na, Zhu, Jiu‑Xin, Yang, Bao‑Feng, Dong, De‑Li

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 1.16 MB

english, 2012

8

α-Haemoglobin regulates sympathoadrenal cell metabolism to maintain a catecholaminergic phenotype

Marcos-Almaraz, María T., Rodríguez-Gómez, José A., López-Barneo, José, Pascual, Alberto

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 648 KB

english, 2012

9

The multifunctional poly(A)-binding protein (PABP) 1 is subject to extensive dynamic post-translational modification, which molecular modelling suggests plays an important role in co-ordinating its activities

Brook, Matthew, McCracken, Lora, Reddington, James P., Lu, Zhi-Liang, Morrice, Nicholas A., Gray, Nicola K.

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 1.31 MB

english, 2012

10

Detection of Rho GEF and GAP activity through a sensitive split luciferase assay system

Anderson, Erik L., Hamann, Michael J.

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 1.01 MB

english, 2012

11

Thrombin-induced shedding of tumour endothelial marker 5 and exposure of its RGD motif are regulated by cell-surface protein disulfide-isomerase

Vallon, Mario, Aubele, Philipp, Janssen, Klaus-Peter, Essler, Markus

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 495 KB

english, 2012

12

LL37 and hBD-3 elevate the β-1,3-exoglucanase activity of Candida albicans Xog1p, resulting in reduced fungal adhesion to plastic

Chang, Hao-Teng, Tsai, Pei-Wen, Huang, Hsin-Hui, Liu, Yu-Shu, Chien, Tzu-Shan, Lan, Chung-Yu

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 556 KB

english, 2012

13

Ubiquitin-specific protease 4 (USP4) targets TRAF2 and TRAF6 for deubiquitination and inhibits TNFα-induced cancer cell migration

Xiao, Ning, Li, Hui, Luo, Jian, Wang, Rui, Chen, Haiquan, Chen, Jiquan, Wang, Ping

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 843 KB

english, 2012

14

Crystallographic and X-ray absorption spectroscopic characterization of Helicobacter pylori UreE bound to Ni 2+ and Zn 2+ reveals a role for the disordered C-terminal arm in metal trafficking

Banaszak, Katarzyna, Martin-Diaconescu, Vlad, Bellucci, Matteo, Zambelli, Barbara, Rypniewski, Wojciech, Maroney, Michael J., Ciurli, Stefano

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 1.02 MB

english, 2012

15

Leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation is associated with cell-type-dependent splicing of mtAspRS mRNA

van Berge, Laura, Dooves, Stephanie, van Berkel, Carola G.M., Polder, Emiel, van der Knaap, Marjo S., Scheper, Gert C.

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 462 KB

english, 2012

16

The p101 subunit of PI3Kγ restores activation by Gβ mutants deficient in stimulating p110γ

Shymanets, Aliaksei, Ahmadian, Mohammad R., Kössmeier, Katja T., Wetzker, Reinhard, Harteneck, Christian, Nürnberg, Bernd

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 642 KB

english, 2012

17

Changes in the ratio of free NEDD8 to ubiquitin triggers NEDDylation by ubiquitin enzymes

Hjerpe, Roland, Thomas, Yann, Chen, Jesse, Zemla, Aleksandra, Curran, Siobhan, Shpiro, Natalia, Dick, Lawrence R., Kurz, Thimo

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 969 KB

english, 2012

18

BRCA1-mediated repression of mutagenic end-joining of DNA double-strand breaks requires complex formation with BACH1

Dohrn, Lisa, Salles, Daniela, Siehler, Simone Y., Kaufmann, Julia, Wiesmüller, Lisa

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 613 KB

english, 2012

19

Modulation of glucokinase by glucose, small-molecule activator and glucokinase regulatory protein: steady-state kinetic and cell-based analysis

Bourbonais, Francis J., Chen, Jing, Huang, Cong, Zhang, Yanwei, Pfefferkorn, Jeffrey A., Landro, James A.

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 364 KB

english, 2012

20

Abi-1-bridged tyrosine phosphorylation of VASP by Abelson kinase impairs association of VASP to focal adhesions and regulates leukaemic cell adhesion

Maruoka, Masahiro, Sato, Mizuho, Yuan, Yunfeng, Ichiba, Masayoshi, Fujii, Ryosuke, Ogawa, Takuya, Ishida-Kitagawa, Norihiro, Takeya, Tatsuo, Watanabe, Naoki

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 1.06 MB

english, 2012

21

Platelet-derived growth factor-C (PDGF-C) activation by serine proteases: implications for breast cancer progression

Hurst, Newton J., Najy, Abdo J., Ustach, Carolyn V., Movilla, Lisa, Kim, Hyeong-Reh Choi

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 630 KB

english, 2012

22

Identification of persulfide-binding and disulfide-forming cysteine residues in the NifS-like domain of the molybdenum cofactor sulfurase ABA3 by cysteine-scanning mutagenesis

Lehrke, Markus, Rump, Steffen, Heidenreich, Torsten, Wissing, Josef, Mendel, Ralf R., Bittner, Florian

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 2.07 MB

english, 2012

23

Homo- and hetero-dimeric architecture of the human liver Na + -dependent taurocholate co-transporting protein

Bijsmans, Ingrid T. G. W., Bouwmeester, Rianne A. M., Geyer, Joachim, Faber, Klaas Nico, van de Graaf, Stan F. J.

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 1.04 MB

english, 2012

24

The adaptor protein 14-3-3 binds to the calcium-sensing receptor and attenuates receptor-mediated Rho kinase signalling

Arulpragasam, Ajanthy, Magno, Aaron L., Ingley, Evan, Brown, Suzanne J., Conigrave, Arthur D., Ratajczak, Thomas, Ward, Bryan K.

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 787 KB

english, 2012

25

The full-length Streptococcus pneumoniae major pilin RrgB crystallizes in a fibre-like structure, which presents the D1 isopeptide bond and provides details on the mechanism of pilus polymerization

El Mortaji, Lamya, Contreras-Martel, Carlos, Moschioni, Monica, Ferlenghi, Ilaria, Manzano, Clothilde, Vernet, Thierry, Dessen, Andrea, Di Guilmi, Anne Marie

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 1.35 MB

english, 2012

26

Inactivation of mitochondrial aspartate aminotransferase contributes to the respiratory deficit of yeast frataxin-deficient cells

Sliwa, Dominika, Dairou, Julien, Camadro, Jean-Michel, Santos, Renata

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 475 KB

english, 2012