Volume 78; Issue 7

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Biochemical Pharmacology
Volume 78; Issue 7

Biochemical Pharmacology

Volume 78; Issue 7

1

nAChR agonist-induced cognition enhancement: Integration of cognitive and neuronal mechanisms

Martin Sarter, Vinay Parikh, William M. Howe

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 393 KB

english, 2009

2

Nicotinic actions on neuronal networks for cognition: General principles and long-term consequences

Rogier B. Poorthuis, Natalia A. Goriounova, Jonathan J. Couey, Huibert D. Mansvelder

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 216 KB

english, 2009

3

Multiple roles for nicotine in Parkinson's disease

Maryka Quik, Luping Z. Huang, Neeraja Parameswaran, Tanuja Bordia, Carla Campos, Xiomara A. Perez

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 504 KB

english, 2009

4

Age dependent nicotinic influences over dopamine neuron synaptic plasticity

Andon N. Placzek, Tao A. Zhang, John A. Dani

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 224 KB

english, 2009

5

Alpha9 nicotinic acetylcholine receptors and the treatment of pain

J. Michael McIntosh, Nathan Absalom, Mary Chebib, Ana Belén Elgoyhen, Michelle Vincler

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 238 KB

english, 2009

6

Nicotinic antagonist effects in the mediodorsal thalamic nucleus: Regional heterogeneity of nicotinic receptor involvement in cognitive function

Reginald Cannady, Ruth Weir, Boyoung Wee, Emily Gotschlich, Nadeem Kolia, Edward Lau, Jesse Brotherton, Edward D. Levin

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 513 KB

english, 2009

7

Selectivity of ABT-089 for α4β2* and α6β2* nicotinic acetylcholine receptors in brain

Michael J. Marks, Charles R. Wageman, Sharon R. Grady, Murali Gopalakrishnan, Clark A. Briggs

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 401 KB

english, 2009

8

The nicotinic receptor of cochlear hair cells: A possible pharmacotherapeutic target?

Ana Belén Elgoyhen, Eleonora Katz, Paul A. Fuchs

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 258 KB

english, 2009

9

Structural and functional diversity of native brain neuronal nicotinic receptors

Cecilia Gotti, Francesco Clementi, Alice Fornari, Annalisa Gaimarri, Stefania Guiducci, Irene Manfredi, Milena Moretti, Patrizia Pedrazzi, Luca Pucci, Michele Zoli

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 257 KB

english, 2009

10

TC-5619: An alpha7 neuronal nicotinic receptor-selective agonist that demonstrates efficacy in animal models of the positive and negative symptoms and cognitive dysfunction of schizophrenia

T.A. Hauser, A. Kucinski, K.G. Jordan, G.J. Gatto, S.R. Wersinger, R.A. Hesse, E.K. Stachowiak, M.K. Stachowiak, R.L. Papke, P.M. Lippiello, M. Bencherif

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 395 KB

english, 2009

11

Polypeptide and peptide toxins, magnifying lenses for binding sites in nicotinic acetylcholine receptors

Victor Tsetlin, Yuri Utkin, Igor Kasheverov

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 464 KB

english, 2009

12

Preclinical pharmacology of the α4β2 nAChR partial agonist varenicline related to effects on reward, mood and cognition

Hans Rollema, Mihály Hajós, Patricia A. Seymour, Rouba Kozak, Mark J. Majchrzak, Victor Guanowsky, Weldon E. Horner, Doug S. Chapin, William E. Hoffmann, David E. Johnson, Stafford Mclean, Jody Freema

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 562 KB

english, 2009

13

Nicotinic receptor-based therapeutics and candidates for smoking cessation

Linda P. Dwoskin, Andrew M. Smith, Thomas E. Wooters, Zhenfa Zhang, Peter A. Crooks, Michael T. Bardo

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 269 KB

english, 2009

14

Nicotinic acetylcholine receptors and the ascending dopamine pathways

Phil D. Livingstone, Susan Wonnacott

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 727 KB

english, 2009

15

Nicotine-induced upregulation of nicotinic receptors: Underlying mechanisms and relevance to nicotine addiction

Anitha P. Govind, Paul Vezina, William N. Green

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 200 KB

english, 2009

16

A review of experimental techniques used for the heterologous expression of nicotinic acetylcholine receptors

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 266 KB

english, 2009

17

Measurement of affective state during chronic nicotine treatment and withdrawal by affective taste reactivity in mice: The role of endocannabinoids

Victoria C. Wing, Barbara Cagniard, Niall P. Murphy, Mohammed Shoaib

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 525 KB

english, 2009

18

Comparative pharmacology and computational modelling yield insights into allosteric modulation of human α7 nicotinic acetylcholine receptors

David B. Sattelle, Steven D. Buckingham, Miki Akamatsu, Kazuhiko Matsuda, Ilse Pienaar, Andrew K. Jones, Benedict M. Sattelle, Andrew Almond, Charles D. Blundell

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 628 KB

english, 2009

19

Stimulation of dopamine release by nicotinic acetylcholine receptor ligands in rat brain slices correlates with the profile of high, but not low, sensitivity α4β2 subunit combination

David J. Anderson, John Malysz, Jens Halvard Grønlien, Rachid El Kouhen, Monika Håkerud, Caroline Wetterstrand, Clark A. Briggs, Murali Gopalakrishnan

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 446 KB

english, 2009

20

Functional consequences of adaptive evolution of the mammalian α9α10 nicotinic receptor

M. Lipovsek, L.F. Franchini, E. Katz, N.S. Millar, P.A. Fuchs, A.B. Elgoyhen

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 248 KB

english, 2009

21

The nicotinic acetylcholine receptors of Ascaris suum

H.M. Bennett, S.M. Williamson, S. McCavera, A.P. Robertson, R.J. Martin, T. Williams, D.J. Woods, D.B. Sattelle, A.J. Wolstenholme

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 261 KB

english, 2009

22

Pharmacological chaperoning of nicotinic receptors begins in the endoplasmic reticulum: Compartments and stoichiometries

Rahul Srinivasan, Rigo Pantoja, Sindhuja Kadambi, Elisha D.W. Mackey, Shelly Tzlil, Fraser J. Moss, Henry A. Lester

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 59 KB

english, 2009

23

Pharmacological chaperoning of nicotinic receptors begins in the endoplasmic reticulum: High-resolution imaging

Rigo Pantoja, Rahul Srinivasan, Sindhuja Kadambi, Elisha D.W. Mackey, Shelly Tzlil, Fraser J. Moss, Henry A. Lester

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 79 KB

english, 2009

24

Cloning and functional expression of the nicotinic acetylcholine receptor chaperone RIC-3 from Xenopus laevis

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 66 KB

english, 2009

25

Functional expression of an α5β2 nicotinic acetylcholine receptor

Tanguy Araud, Mario Wanischeck, Roberta Benfante, Ortrud Steinlein, Diego Fornasari, Daniel Bertrand, Jean-Charles Hoda

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 66 KB

english, 2009

26

Gain of function mutants in human or mouse nAChR β3 subunits interchangeably activate either human or mouse α6β4-nAChR, but not human or mouse α6β2-nAChR

Bhagirathi Dash, Minoti Bhakta, Paul Whiteaker, Jerry A. Stizel, Yongchang Chang, Ronald J. Lukas

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 77 KB

english, 2009

27

Characterization of insect nicotinic receptors by heterologous expression: Insecticide selectivity and the influence of molecular chaperones

Toby Collins, Stuart J. Lansdell, Neil S. Millar

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 55 KB

english, 2009

28

Labeled peptide and protein neurotoxins for basic study on nicotinic acetylcholine receptors and for practical applications

Igor Kasheverov, Maxim Zhmak, Alexey Khrushchov, Irina Shelukhina, Elena Kryukova, Victor Tsetlin

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 55 KB

english, 2009

29

Labeling α7 nAChRs on hippocampal neurons using fluorescent analogs of α-conotoxin ArIB[V11L;V16A]

Arik J. Hone, Jesse L. Mohn, Michele Jacob, Paul Whiteaker, J. Michael McIntosh

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 1.99 MB

english, 2009

30

Radioligand binding characterization of [3H]-A-998679: A novel positive allosteric modulator of α4β2 nAChRs

D.J. Anderson, S. Vaidyanathan, M. Namovic, D. Donnelly-Roberts, L. Lee, M. Gopalakrishnan

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 2.00 MB

english, 2009

31

α3* and α7* nAChR mediated Ca2+ transient generation in neuroblastoma IMR-32 cells

H. Ween, K. Thorin-Hagene, E. Andersen, J.H. Gronlien, L. Lee, M. Gopalakrishnan, J. Malysz

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 61 KB

english, 2009

32

Positive allosteric modulation of α7 neuronal nicotinic acetylcholine receptors: Lack of mechanism-based evidence for cytotoxicity in PC12 cells and rat primary cortical neurons

Min Hu, Murali Gopalakrishnan, Jinhe Li

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 61 KB

english, 2009

33

A novel nicotinic antagonist protects the function of hippocampal slices against neurotoxic organophosphates

P.A. Ferchmin, Dinely Perez, A. Henrique Martins, Brenda L. Cuadrado, Marimee Carrasco, Vesna A. Eterovic

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 135 KB

english, 2009

34

From acetyl bispidine to an extended bispidine amide framework: Synthesis and structure–affinity relationships for nicotinic acetylcholine receptors (nAChRs)

D. Gündisch, C. Eibl

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 122 KB

english, 2009

35

Probing the non-competitive binding site within the n-terminal region of α4β2 nicotinic receptors

Gracia X.J. Quek, Jill I. Halliday, Malcolm D. McLeod, Mary Chebib

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 156 KB

english, 2009

36

Mutation of proline enables subtype selectivity of α-conotoxin BuIA

Yelena Filchakova, Amy B. Godoy, Sean Christensen, J. Michael McIntosh

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 80 KB

english, 2009

37

Isoanatabine, a naturally occurring α4β2 nicotinic receptor agonist

H. Xing, A. Rouchaud, S. Keshwah, W.R. Kem

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 99 KB

english, 2009

38

Automated two-electrode voltage clamp for medium-throughput studies of ion channels with non-destructive sample analysis

Dieter D’hoedt, Victor Tsetlin, Sonia Bertrand, Daniel Bertrand

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 64 KB

english, 2009

39

Novel α7 nAChRs ligands: From virtual screening to functional assays

N. Garcia, K.T. Nguyen, S. Bertrand, D. Bertrand, J.L. Reymond

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 64 KB

english, 2009

40

Homology models of the alpha7 acetylcholine receptor based upon bacterial receptors: Comparison of experimental and in silico derived data

Sean C. Barron, Brenda R. Temple, Jennifer A. See, Robert L. Rosenberg, James T. McLaughlin

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 77 KB

english, 2009

41

Heterogenity in release probability and depression dynamics at a nicotinic CNS connection

C.L. Grove, D.S. Faber

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 59 KB

english, 2009

42

Nicotinic receptor activation increases glutamatergic transmission and plasticity in the rat cerebellum

F. Prestori, D. Bertrand, E. D’Angelo

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 73 KB

english, 2009

43

Nicotinic acetylcholine receptors differentially regulate phosphorylation of dopamine target cell proteins in the rat prefrontal cortex

Phil D. Livingstone, James Hockley, Susan Wonnacott

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 61 KB

english, 2009

44

Nicotine activates a dopamine signal that enables in vivo synaptic plasticity of the kind that underlies associative memory

Jianrong Tang, John A. Dani

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 61 KB

english, 2009

45

Distinct neural pathways mediate alpha7 nicotinic acetylcholine receptor-dependent activation of the forebrain

Morten S. Thomsen, Anders Hay-Schmidt, Henrik H. Hansen, Jens D. Mikkelsen

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 60 KB

english, 2009

46

Selectivity of ABT-089 for α4β2* and α6β2* nicotinic acetylcholine receptors in brain

Michael J. Marks, Charles R. Wageman, Sharon R. Grady, Murali Gopalakrishnan, Clark A. Briggs

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 60 KB

english, 2009

47

Role of Sp1 and AP-2 in the transcriptional regulation of the CHRNA7 gene and the link to schizophrenia

Jessica Finlay Schultz, Margaret Short, Sharon Graw, Sherry Leonard

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 60 KB

english, 2009

48

In vitro pharmacological characterization and pro-cognitive effects of the selective alpha-7 nicotinic agonist WYE-103914

J. Dunlop, T.A. Comery, T. Lock, A. Kramer, D. Kowal, S. Yeola, F. Jow, S. Aschmies, Q. Lin, C.E. Beyer, J. Brennan, C. Kelley, R. Roncarati, C. Scali, S. Haydar, C. Ghiron, K.L. Marquis, B. Harrison,

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 62 KB

english, 2009

49

Characterization of the alpha-7 nicotinic receptor agonist WYE-103914 in models relevant to schizophrenia and interaction with antipsychotics

K.L. Marquis, T.A. Comery, R.L. Navarra, S. Leiser, S.M. Grauer, C. Pulicicchio, C. Kelley, R. Roncarati, C. Scali, S. Haydar, C. Ghiron, B. Harrison, A. Robichaud, G.C. Terstappen, J. Dunlop

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 62 KB

english, 2009

50

R3487/MEM 3454, a novel nicotinic alpha 7 receptor partial agonist, improves attention and working memory performance in cynomolgus macaques

T.L. Wallace, G. Chiu, H. Dao, D.A. Lowe, R. Porter, L. Santarelli

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 60 KB

english, 2009

51

Characterization of JNJ-1930942, a novel positive allosteric modulator of the α7 nicotinic acetylcholine receptor

Anne Lesage, Theo Dinklo, Jan-Willem Thuring, Christopher Grantham, Luc Peeters, Hilde Lavreysen, Hamdy Shaban, Karen E. Stevens, Lijun Zheng

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 60 KB

english, 2009

52

Profile of A-716096, a novel thiazolylidine positive allosteric modulator of the α7 nicotinic acetylcholine receptor

D. Donnelly-Roberts, J. Malysz, R. Faghih, H. Gronlien, M. Haakerud, K. Thorin-Hagne, H. Ween, S.M. Gopalakrishnan, M. Hu, J. Li, D.J. Anderson, K. Kohlhaas, M. Namovic, R. Radek, H. Robb, C.A. Briggs

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 86 KB

english, 2009

53

2,2-Dimethylcyclopropyl-benzamides: Novel positive allosteric modulators of α7 nAChRs

Hans Maag, Daisy Joe Du Bois, David G. Loughhead, Jason Manka, Dinah Misner, Sunil Sahdeo, David B. Smith

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 73 KB

english, 2009

54

In vitro and in vivo characterization of PheTQS, a novel α7 nAChR positive allosteric modulator

James N.C. Kew, Selina Mok, Annette Weil, Caterina Virginio, Laura Castelletti, Eric Southam, Carol Jennings, Lee A. Dawson, Laurent P. Lacroix, Abbe Martyn, Simon Teague, Zeenat Atcha, Darrel Pembert

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 73 KB

english, 2009

55

Dual allosteric modulators of neuronal nicotinic-acetylcholine and GABAA receptors

Kelvin Gee, Derk Hogenkamp, Tim Johnstone

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 83 KB

english, 2009

56

Effects of 4R,6R-cembratriene diol on human α7 nicotinic acetylcholine receptor

William Castro, Richard Hann, Vesna A. Eterovi

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 57 KB

english, 2009

57

Characterization of type I and type II positive allosteric modulators of α7 nicotinic acetylcholine receptors

Gareth T. Young, Neil S. Millar

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 57 KB

english, 2009

58

Chronic nicotine exposure differentially alters gene expression in VTA from adolescent and adult rats

Menahem B. Doura, Norman H. Lee, David C. Perry

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 71 KB

english, 2009

59

Nicotine persistently activates prefrontal layer VI pyramidal neurons through α5 subunit-containing α4β2* nicotinic acetylcholine receptors

C.D. Bailey, N.C. Alves, M. De Biasi, E.K. Lambe

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 60 KB

english, 2009

60

Distinct pharmacological profiles for nicotinic AChR-evoked noradrenaline release in rat frontal cortex and hippocampus

Alexandra Kennett, David Heal, Susan Wonnacott

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 76 KB

english, 2009

61

Functional interaction between presynaptic nicotinic and D2 receptors on dopaminergic nerve endings of rat and mouse nucleus accumbens

Mario Marchi, Stefania Zappettini, Massimo Grilli, Federica Lagomarsino, Michele Zoli

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 62 KB

english, 2009

62

Effects of nicotine on real-time dopamine dynamics in rat nucleus accumbens: In vivo voltammetric study

V.P. Grinevich, J.A. O’Connor, M. Bencherif, E.A. Budygin

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 62 KB

english, 2009

63

Effect of partial nicotinic agonists on real-time dopamine responses in rat nucleus accumbens: In vivo voltammetric study

J.A. O’Connor, E.A. Budygin, V.P. Grinevich, M. Bencherif

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 59 KB

english, 2009

64

An mGlu2/3 receptor agonist blocks increases in nucleus accumbens shell dopamine induced by self-administered, but not experimenter-administered, nicotine in rats

M.S. D'Souza, M.E. Liechti, A.M. Ramirez, R. Kuczenski, A. Markou

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 59 KB

english, 2009

65

GABAB receptor positive modulators: Effects on nicotine self-administration and cue-induced reinstatement of nicotine-seeking behavior in rats

Styliani Vlachou, Sébastien Guery, Wolfgang Froestl, Klemens Kaupmann, Deboshri Banerjee, M.G. Finn, Athina Markou

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 72 KB

english, 2009

66

The localization of neuronal nicotinic receptors (nAChRs) in the zebra finch brain tested under naïve, nicotine-on board and nicotine withdrawal conditions

Susanne Cappendijk, Daniel Pirvan, Brett Mulvey, Monica Rodriguez, Michael Marks

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 60 KB

english, 2009

67

Preclinical properties of the α4β2 nAChR partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence

H. Rollema, A. Shrikhande, K.M. Ward, J.W. Coe, E. Tseng, E.Q. Wang, M. De Vries, T.H.I.F. Cremers, S. Bertrand, D. Bertrand

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 70 KB

english, 2009

68

Low efficacy partial agonists of the α4β2 nicotinic acetylcholine receptor (nAChR). Does functional efficacy govern in vivo response?

Jotham W. Coe, Paige R. Brooks, Michael C. Wirtz, Michael G. Vetelino, Eric P. Arnold, Steven B. Sands, Thomas I. Davis, Lorraine A. Lebel, Carol B. Fox, Alka Shrikhande, Robert S. Mansbach, Leslie K.

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 56 KB

english, 2009

69

The nAChR agonist AMOP-H-OH (‘sazetidine-A’) exhibits reinforcing, but not withdrawal-alleviating, properties in rats

Adrian Hackett, Barbara Caldarone, Alan P. Kozikowski, Afshin Ghavami, Berend Olivier, Taleen Hanania, Neil E. Paterson

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 56 KB

english, 2009

70

In vitro pharmacological profile of a novel α4β2 positive allosteric modulator NS9283 (A-969933)

J. Malysz, T. Dyhring, P.K. Ahring, G.M. Olsen, D. Peters, J.H. Gronlien, C. Wetterstrand, H. Ween, M. Haakerud, K. Thorin-Hagene, E. Andersen, D.J. Anderson, M. Hu, P.E. Kroeger, C.-H.L. Lee, M. Gopa

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 64 KB

english, 2009

71

Improving the efficacy-tolerability profile of nAChR agonists for the treatment of neuropathic pain in combination with positive allosteric modulators

Chih-Hung Lee, Chang Zhu, Thomas Campbell, Thomas Shaughnessy, Prisca Honore, James Polakowski, Murali Gopalakrishnan

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 55 KB

english, 2009

72

In vivo characterization of the co-administration of α4β2 neuronal nicotinic receptor agonist and positive allosteric modulator in experimental pain in rats

Chang Z. Zhu, Chih-liang Chin, Chengmin Zhong, Joe Mikusa, Prasant Chandran, Anita Salyers, Erica Wensink, Gricelda Silmer, La Geisha Lewis, Donna Gauvin, Scott Baker, Ann Tovcimak, Jordan Brown, Nath

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 55 KB

english, 2009

73

Positive allosteric modulation of α4β2 nicotinic receptors potentiates some CNS effects of the α4β2 agonist, ABT-594

S.R. Franklin, E.G. Mohler, V.A. Komater, H. Robb, R.J. Radek, N.R. Rustay, J.W. Brown, M. Gopalakrishnan, M.W. Decker, L.E. Rueter

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 58 KB

english, 2009

74

GZ556A and ZZ204G are novel small molecule antagonists of α9α10 nAChRs and are analgesic in rats

J.M. McIntosh, L.P. Dwoskin, P.A. Crooks, J.R. Holtman Jr.

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 58 KB

english, 2009

75

Antidepressant-like activity of AMOP-H-OH (‘sazetidine-A’) in the forced swim test is mediated by high affinity nicotinic acetylcholine receptors

B.J. Caldarone, M. Manzano, N.E. Paterson, A.P. Kozikowksi, B.E. Olivier, A. Ghavami

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 71 KB

english, 2009

76

nAChR agonists reduce l-dopa-induced dyskinesias in parkinsonian rats

M. Quik, L.Z. Huang, Y. Lee, I.F. Carroll, N. Parameswaran

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 60 KB

english, 2009

77

Importance of nicotinic acetylcholine receptors in the visual adverse effects associated with telithromycin

D. Bertrand, S. Bertrand, P. Fernandes

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 60 KB

english, 2009

78

Expression and characterization of nicotinic receptor polymorphisms in lung cancer cell lines

J.A. Hollister-Smith, P. Song, E.R. Spindel

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 54 KB

english, 2009

79

“Neuron-like” communication between nicotinic signaling and GABA signaling in bronchial epithelial cells: Implications for the link between smoking, asthma and COPD

Xiao Wen Fu, Eliot R. Spindel

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 54 KB

english, 2009

80

Nicotine suppresses hyperexcitability of inflamed colonic sensory neurons

G.R. Abdrakhmanova, H.I. Akbarali, Sh. Al Sharari, M.I. Damaj

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 122 KB

english, 2009

81

Anti-inflammatory effects of α4β2 nicotinic receptor activation revealed through microarray analysis of nicotine-induced gene changes

Vishnu Hosur, Scott Leppanen, Adham Abutaha, Michael Marks, Ralph H. Loring

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 122 KB

english, 2009

82

Role of α7 nicotinic acetylcholine receptors in regulating tumor necrosis factor-α (TNF-α) as Revealed by subtype selective agonists

Jinhe Li, Suzanne L. Mathieu, Richard Harris, Jianguo Ji, David J. Anderson, John Malysz, William H. Bunnelle, Jeffrey F. Waring, Kennan C. Marsh, Anwar Murtaza, Lisa M. Olson, Murali Gopalakrishnan

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 124 KB

english, 2009

83

GTS-21 inhibits pro-inflammatory cytokine release independent of the Toll-like receptor stimulated via a transcriptional mechanism involving JAK2 activation

Matthijs Kox, Jeroen F. van Velzen, Jan C. Pompe, Cornelia W. Hoedemaekers, Johannes G. van der Hoeven, Peter Pickkers

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 325 KB

english, 2009

84

Insight in nAChR subtype selectivity from AChBP crystal structures

Prakash Rucktooa, August B. Smit, Titia K. Sixma

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 1.01 MB

english, 2009

85

Enhanced nicotine reward in adulthood after exposure to nicotine during early adolescence in mice

Dena Kota, Susan E. Robinson, M. Imad Damaj

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 372 KB

english, 2009

86

Nicotinic Acetylcholine Receptors as Therapeutic Targets: Emerging Frontiers in Basic Research and Clinical Science—Editorial Perspective

Daniel Bertrand, Murali Gopalakrishnan, Diana Donnelly-Roberts

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 52 KB

english, 2009

87

A reversible model of the cognitive impairment associated with schizophrenia in monkeys: Potential therapeutic effects of two nicotinic acetylcholine receptor agonists

Jerry J. Buccafusco, Alvin V. Terry Jr.

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 651 KB

english, 2009

88

Selective α7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes

Simon Sydserff, E.J. Sutton, Dekun Song, Michael C. Quirk, Carla Maciag, Chaoying Li, Gerald Jonak, David Gurley, John C. Gordon, Edward P. Christian, James J. Doherty, Tom Hudzik, Edwin Johnson, Ladi

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 427 KB

english, 2009

89

The novel nicotinic receptor antagonist, N,N′-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB), inhibits nicotine-evoked [3H]norepinephrine overflow from rat hippocampal slices

Andrew M. Smith, Gurpreet K. Dhawan, Zhenfa Zhang, Kiran B. Siripurapu, Peter A. Crooks, Linda P. Dwoskin

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 251 KB

english, 2009

90

Editorial Advisory Board

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 31 KB

english, 2009

91

Graphical Abstracts Contents

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 1.74 MB

english, 2009

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