Volume 86; Issue 8

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Biochemical Pharmacology
Volume 86; Issue 8

Biochemical Pharmacology

Volume 86; Issue 8

1

Structural insights into Cys-loop receptor function and ligand recognition

Nys, Mieke, Kesters, Divya, Ulens, Chris

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 590 KB

english, 2013

2

Potential substrates for nicotine and alcohol interactions: A focus on the mesocorticolimbic dopamine system

Doyon, William M., Thomas, Alyse M., Ostroumov, Alexey, Dong, Yu, Dani, John A.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 363 KB

english, 2013

3

Nicotine signaling and progression of chronic kidney disease in smokers

Jain, Gaurav, Jaimes, Edgar A.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 711 KB

english, 2013

4

Transcriptional regulation by nicotine in dopaminergic neurons

Henley, Beverley M., Williams, Brian A., Srinivasan, Rahul, Cohen, Bruce N., Xiao, Cheng, Mackey, Elisha D.W., Wold, Barbara J., Lester, Henry A.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.46 MB

english, 2013

5

Complex relationships of nicotinic receptor actions and cognitive functions

Levin, Edward D.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 450 KB

english, 2013

6

Cognition as a therapeutic target in late-life depression: Potential for nicotinic therapeutics

Zurkovsky, Lilia, Taylor, Warren D., Newhouse, Paul A.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 304 KB

english, 2013

7

Cortical control of VTA function and influence on nicotine reward

Wu, Jie, Gao, Ming, Shen, Jian-Xin, Shi, Wei-Xing, Oster, Andrew M., Gutkin, Boris S.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.36 MB

english, 2013

8

Choline transporter hemizygosity results in diminished basal extracellular dopamine levels in nucleus accumbens and blunts dopamine elevations following cocaine or nicotine

Dong, Yu, Dani, John A., Blakely, Randy D.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 364 KB

english, 2013

9

Effects of neuronal nicotinic acetylcholine receptor allosteric modulators in animal behavior studies

Pandya, Anshul A., Yakel, Jerrel L.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 501 KB

english, 2013

10

Nicotinic modulation of intrinsic brain networks in schizophrenia

Smucny, Jason, Tregellas, Jason

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 915 KB

english, 2013

11

Evaluating the role of the alpha-7 nicotinic acetylcholine receptor in the pathophysiology and treatment of schizophrenia

Young, Jared W., Geyer, Mark A.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 666 KB

english, 2013

12

Biogenesis, trafficking and up-regulation of nicotinic ACh receptors

Colombo, Sara Francesca, Mazzo, Francesca, Pistillo, Fancesco, Gotti, Cecilia

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 770 KB

english, 2013

13

Vestibular dysfunction in alpha9 and alpha9/10 knockout mice

Morley, Barbara, Vijayakumar, Sarath, Menapace, Deeana, Jones, Timothy

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 242 KB

english, 2013

14

Editorial Board

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 39 KB

english, 2013

15

Nicotinic acetylcholine receptors controlling attention: Behavior, circuits and sensitivity to disruption by nicotine

Poorthuis, Rogier B., Mansvelder, Huibert D.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 843 KB

english, 2013

16

Nicotinic regulation in a hyperdopaminergic state

Aline, Ostos-Valverde, Galicia, O., Sanchez-Castillo, H.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 290 KB

english, 2013

17

Dicarba modification of α-conotoxin RgIA conferring selectivity towards α9α10 nicotinic acetylcholine receptors

Kompella, S.N., van Lierop, B.J., Robinson, S.D., Belgi, A., Callaghan, B., Hung, A., MacRaild, C.A., Norton, R.S., Robinson, A.J., Adams, D.J.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 190 KB

english, 2013

18

Varenicline ameliorates spatial and temporal gait deficits following 3-acetylpyridine-induced ataxia in rats

Lambert, C.S., Philpot, R.M., Engberg, M.E., Wecker, L.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 140 KB

english, 2013

19

The deletion of both the α9 and α10 nAChR subunits results in a different phenotype than the single deletion of the α9 or α10 subunit

Morley, B.J., Dolan, D.F., Halsey, K., Simmons, D.D.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 94 KB

english, 2013

20

Nicotine effects on time perception in rats

Sanchez-Castillo, H., Rivera, I. Gonzalez, Valverde, A. Ostos, Paz-Trejo, D., Galicia, O.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 142 KB

english, 2013

21

Functional role of alpha7 nicotinic receptor in chronic neuropathic and inflammatory pain: Studies in transgenic mice

AlSharari, Shakir D., Freitas, Kelen, Damaj, M. Imad

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.00 MB

english, 2013

22

Proteomic investigation of human α7-nicotinic acetylcholine receptor signaling mechanisms

Mulcahy, Matthew J., Lukas, Ronald J., Barrantes, Francisco J., Hawrot, Edward

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 288 KB

english, 2013

23

A Type-II positive allosteric modulator of α7 nAChRs significantly reduces brain injury and improves neurological function after focal cerebral ischemia in rats

Uteshev, Victor V., Jin, Kunlin, Sun, Fen

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 289 KB

english, 2013

24

Neuronal nicotinic receptors as analgesic targets: It's a winding road

Umana, Iboro C., Daniele, Claire A., McGehee, Daniel S.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 449 KB

english, 2013

25

Effects of positive allosteric modulators (PAMs) of nicotinic receptors on intracellular Ca2+ concentration [Ca2+]i in mouse embryonic mesencephalic neurons in primary culture

Cosi, Cristina, Marty, Fabien, Maillos, Philippe, Moser, Paul

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 185 KB

english, 2013

26

Multiple CNS nicotinic receptors mediate l-dopa-induced dyskinesias: Studies with parkinsonian nicotinic receptor knockout mice

Quik, Maryka, Campos, Carla, Grady, Sharon R.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 637 KB

english, 2013

27

Null mutation of the β2 nAChR subunit attenuated anhedonia induced by spontaneous and mecamylamine-precipitated nicotine withdrawal in mice

Stoker, Astrid K., Marks, Michael J., Markou, Athina

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 187 KB

english, 2013

28

Discovery of Lu AF58801, a novel, selective and brain penetrant positive allosteric modulator of alpha-7 nicotinic acetylcholine receptors: Attenuation of subchronic phencyclidine (PCP)-induced cognitive deficits in rats following oral administration

Bastlund, Jesper F., Bundgaard, Christoffer, Dekermendjian, Kim, Papke, Roger L., Redrobe, John P., Frederiksen, Kristen, Eskildsen, Jørgen

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 186 KB

english, 2013

29

Structures of α7 and α4β2 nAChR transmenbrane domains and associated binding sites for allosteric modulators

Bondarenko, Vasyl, Mowrey, David, Xu, Yan, Tang, Pei

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 141 KB

english, 2013

30

Nicotinic α4β2 antagonist treatment attenuates impairments in radial-arm maze repeated acquisition caused by dizocilpine in rats

Burke, Dennis, Levin, Edward D.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 186 KB

english, 2013

31

Nicotinic receptor-mediated direct and indirect excitation of periaqueductal gray neurons that project to the rostral ventromedial medulla

Umana, I.C., Daniele, C.A., McGehee, D.S.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 186 KB

english, 2013

32

Nicotine-induced subunit stoichiometry affects the stability and intracellular trafficking of α3β4 nicotinic receptors

Mazzo, Francesca, Pistillo, Francesco, Clementi, Francesco, Borgese, Nica, Gotti, Cecilia, Colombo, Sara Francesca

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 320 KB

english, 2013

33

Nicotine perturbs PFC–VTA coupling: A new mechanism for nicotine addiction

Gao, M., Lukas, R.J., Wu, J.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 288 KB

english, 2013

34

Contents

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 149 KB

english, 2013

35

Does the β2 C loop of the neuronal nicotinic acetylcholine receptor dictate the type of allosteric modulation?

Levandoski, M.M., Short, C.A., Sibbald, C.A., Kljaic, T.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 144 KB

english, 2013

36

Nicotinic acetylcholine receptor regulation of striatal dopamine transmission: The different requirement for diverse subtypes in ventral versus dorsal striatum

Exley, Richard, McIntosh, J. Michael, Marks, Michael, Maskos, Uwe, Cragg, Stephanie J.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 293 KB

english, 2013

37

In vitro exposure to nicotine modulate the function of presynaptic NMDA receptors present on dopaminergic terminals in rat Nucleus Accumbens

Marchi, M., Salamone, A., Zappettini, S., Grilli, M., Olivero, G., Chen, J., Cunha, R., Pittaluga, A.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 187 KB

english, 2013

38

Nicotinic acetylcholine receptors as therapeutic targets: Emerging frontiers in basic research and clinical science—Editorial comments

Dani, John A., Donnelly-Roberts, Diana, Bertrand, Daniel

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 102 KB

english, 2013

39

Mining the depths of chemical space for new nicotinic ligands

Ruddigkeit, Lars, Awale, Mahendra, Reymond, Jean-Louis

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 187 KB

english, 2013

40

Genetic matters: Thirty years of progress using mouse models in nicotinic research

Marks, Michael J.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 445 KB

english, 2013

41

Novel strategy of blocking nAChR revealed by dissecting a dimeric conotoxin αD-GeXXA

Kompella, S.N., Xu, S., Zhang, T., Yan, M., Shao, X., Chi, C., Ding, J., Wang, C., Adams, D.J.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 144 KB

english, 2013

42

Cellular and synaptic mechanisms of nicotine aversion

Wolfman, S.L., Metz, R.A.E., Hatz, S., McGehee, D.S.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 186 KB

english, 2013

43

Functional chimera of the human α7 acetylcholine receptor for mechanistic investigations of allosteric modulation

Tillman, Tommy S., Seyoum, Edom, Xu, Yan, Tang, Pei

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 286 KB

english, 2013

44

Nicotine decreases ethanol-induced dopamine signaling and increases ethanol self-administration via stress hormones

Thomas, A.M., Doyon, W.M., Dong, Y., Ostroumov, A., Zhang, T.A., Dani, J.A.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 333 KB

english, 2013

45

Characterization of BNC375, a novel α7 nAChR positive allosteric modulator for the treatment of cognitive impairment in Alzheimer's disease

Grishin, A.A., Huyard, B., Coles, C., Kolesik, P., Kolev, Y., Wagner, S., Anddriambeloson, E., Harvey, A., O’Connor, S.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 290 KB

english, 2013

46

Pharmacokinetics and toxicity of a neuroprotective cembranoid

Ferchmin, P., Catz, P., Furimsky, A., O’Loughlin, K., Rausch, L., Green, C., Eterovic, V.A.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 187 KB

english, 2013

47

Subunit composition and kinetics of the Renshaw cell heteromeric nicotinic receptors

Lamotte d’Incamps, Boris, Ascher, Philippe

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 967 KB

english, 2013

48

Nicotinic acetylcholine receptors containing the α6 subunit contribute to ethanol activation of ventral tegmental area dopaminergic neurons

Liu, Liwang, Zhao-Shea, Rubing, McIntosh, J. Michael, Tapper, Andrew R.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.14 MB

english, 2013

49

Antipsychotic compounds show inhibition of the human nicotinic acetylcholine α-7 receptor at high concentrations

Frederiksen, Kristen, Bundgaard, Christoffer, Dekermendjian, Kim, Redrobe, John P., FullertonStøier, Jonatan, Eskildsen, Jørgen, Bastlund, Jesper F.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 185 KB

english, 2013

50

An additional binding site for methyllycaconitine (MLA) and analogs occurs at the α4–α4 interface of the (α4)3(β2)2 nAChR

Chebib, Mary, Absalom, Nathan L., Quek, Gracia, Indurthi, Dinesh, Lewis, Trevor M., Qudah, Taima, von Arenstorff, Ida, Halliday, Jill I., Ambrus, Joseph I., Harpsøe, Kasper, Karim, Nasiara, Balle, Tho

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 176 KB

english, 2013

51

Pacemaking of midbrain habenular cholinergic neurons in nicotine withdrawal

Görlich, Andreas, Antolin-Fontes, Beatriz, Ables, Jessica L., Frahm, Silke, Ślimak, Marta A., Dougherty, Joseph D., Ibañez-Tallon, Inés

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 187 KB

english, 2013

52

Protective activity of (1S,2E,4R,6R,7E,11E)-2,7,11-cembratriene-4,6-diol analogues against diisopropylfluorophosphate neurotoxicity

Eterovic, V.A., Del Valle-Rodrigez, A., Perez, D., Carrasco, M., Khanfar, M.A., El Sayed, K.A., Ferchmin, P.A.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 188 KB

english, 2013

53

Dendritic spine density of prefrontal layer VI neurons is disrupted following chronic in vivo nicotine exposure in development

Kang, Lily, Bailey, Craig D.C., Tian, Michael K., Lambe, Evelyn K.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 190 KB

english, 2013

54

Region-specific cholinergic excitation of layer VI cortical neurons depends on receptor balance and chrna5 expression

Tian, Michael K., Bailey, Craig D.C., Lambe, Evelyn K.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 334 KB

english, 2013

55

α7 Nicotinic receptor agonist reactivates neurogenesis in adult brain

Narla, Sridhar, Klejbor, Ilona, Birkaya, Barbara, Lee, Yu-Wei, Morys, Janusz, Stachowiak, Ewa K., Terranova, Christopher, Bencherif, Merouane, Stachowiak, Michal K.

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.15 MB

english, 2013

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