Volume 33; Issue 4

Biochemical Society Transactions

Volume 33; Issue 4

1

MutYH (MYH) and colorectal cancer

Sampson, J.R., Jones, S., Dolwani, S., Cheadle, J.P.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 244 KB

english, 2005

2

Localization and function of Arf family GTPases

Donaldson, J.G., Honda, A.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 301 KB

english, 2005

3

Flavocytochrome P450 BM3: an update on structure and mechanism of a biotechnologically important enzyme

Warman, A.J., Roitel, O., Neeli, R., Girvan, H.M., Seward, H.E., Murray, S.A., McLean, K.J., Joyce, M.G., Toogood, H., Holt, R.A., Leys, D., Scrutton, N.S., Munro, A.W.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 399 KB

english, 2005

4

Biodiversity of cytochrome P450 redox systems

McLean, K.J., Sabri, M., Marshall, K.R., Lawson, R.J., Lewis, D.G., Clift, D., Balding, P.R., Dunford, A.J., Warman, A.J., McVey, J.P., Quinn, A.-M., Sutcliffe, M.J., Scrutton, N.S., Munro, A.W.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 296 KB

english, 2005

5

A study of the horseradish peroxidase catalytic site by FTIR spectroscopy

Ingledew, W.J., Rich, P.R.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 259 KB

english, 2005

6

Vitamin B12: chemistry and biochemistry

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 282 KB

english, 2005

7

The role of the Wnt signalling pathway in colorectal tumorigenesis

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 140 KB

english, 2005

8

Phenotype associated with recessively inherited mutations in DNA mismatch repair (MMR) genes

de Vos, M., Hayward, B., Bonthron, D.T., Sheridan, E.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 106 KB

english, 2005

9

The production of hydrogen peroxide during early-stage protein aggregation: a common pathological mechanism in different neurodegenerative diseases?

Tabner, B.J., Turnbull, S., Fullwood, N.J., German, M., Allsop, D.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 127 KB

english, 2005

10

Molecular chaperones as therapeutic targets in amyotrophic lateral sclerosis

Kalmar, B., Kieran, D., Greensmith, L.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 51 KB

english, 2005

11

Evidence suggesting that Homo neanderthalensis contributed the H2 MAPT haplotype to Homo sapiens

Hardy, J., Pittman, A., Myers, A., Gwinn-Hardy, K., Fung, H.C., de Silva, R., Hutton, M., Duckworth, J.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 227 KB

english, 2005

12

Mechanism and role of localized activation of Rho-family GTPases in growth factor-stimulated fibroblasts and neuronal cells

Kurokawa, K., Nakamura, T., Aoki, K., Matsuda, M.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 162 KB

english, 2005

13

Epigenetic events in the colorectum and in colon cancer

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 79 KB

english, 2005

14

Cannabinoids and cancer: potential for colorectal cancer therapy: Table 1

Patsos, H.A., Hicks, D.J., Greenhough, A., Williams, A.C., Paraskeva, C.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 59 KB

english, 2005

15

Rewiring photosynthesis: engineering wrong-way electron transfer in the purple bacterial reaction centre

Wakeham, M.C., Jones, M.R.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 259 KB

english, 2005

16

‘Nature-inspired’ drug–protein complexes as inhibitors of Aβ aggregation

Bose, M., Gestwicki, J.E., Devasthali, V., Crabtree, G.R., Graef, I.A.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 388 KB

english, 2005

17

Disease modifying strategies for the treatment of Alzheimer's disease targeted at modulating levels of the β-amyloid peptide

Pangalos, M.N., Jacobsen, S.J., Reinhart, P.H.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 186 KB

english, 2005

18

Presenilin 1: more than just γ-secretase

Raemaekers, T., Esselens, C., Annaert, W.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 68 KB

english, 2005

19

Synaptic plasticity disruption by amyloid β protein: modulation by potential Alzheimer's disease modifying therapies: Figure 1

Rowan, M.J., Klyubin, I., Wang, Q., Anwyl, R.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 194 KB

english, 2005

20

Involvement of presenilins in cell-survival signalling pathways: Table 1

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 80 KB

english, 2005

21

Evidence that vitamin D 3 reverses age-related inflammatory changes in the rat hippocampus

Moore, M.E., Piazza, A., McCartney, Y., Lynch, M.A.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 283 KB

english, 2005

22

Expression of normal sequence pathogenic proteins for neurodegenerative disease contributes to disease risk: ‘permissive templating’ as a general mechanism underlying neurodegeneration

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 63 KB

english, 2005

23

Pathophysiology, pleotrophy and paradigm shifts: genetic lessons from Parkinson's disease

Ross, O.A., Farrer, M.J.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 209 KB

english, 2005

24

Mechanisms of memory loss in Aβ and tau mouse models

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 70 KB

english, 2005

25

Clinicopathological features of the tauopathies

Murray, B., Lynch, T., Farrell, M.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 260 KB

english, 2005

26

The Arf-like GTPase Arl1 and its role in membrane traffic

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 221 KB

english, 2005

27

A role of SAND-family proteins in endocytosis

Poteryaev, D., Spang, A.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 183 KB

english, 2005

28

Integrin regulation of membrane domain trafficking and Rac targeting: Figure 1

Grande-García, A., Echarri, A., Del Pozo, M.A.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 126 KB

english, 2005

29

Insights into biological functions across species: examining the role of Rab proteins in YIP1 family function

Chen, C.Z., Collins, R.N.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 446 KB

english, 2005

30

Membrane curvature and the control of GTP hydrolysis in Arf1 during COPI vesicle formation

Antonny, B., Bigay, J., Casella, J.-F., Drin, G., Mesmin, B., Gounon, P.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 138 KB

english, 2005

31

RhoGDI-3, a promising system to investigate the regulatory function of rhoGDIs: uncoupling of inhibitory and shuttling functions of rhoGDIs

Dransart, E., Morin, A., Cherfils, J., Olofsson, B.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 246 KB

english, 2005

32

A model for Rab GTPase localization: Figure 1

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 83 KB

english, 2005

33

On the action of Brefeldin A on Sec7-stimulated membrane-recruitment and GDP/GTP exchange of Arf proteins: Figure 1

Cherfils, J., Melançon, P.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 300 KB

english, 2005

34

ARL1 has an essential role in Trypanosoma brucei : Figure 1

Price, H.P., Goulding, D., Smith, D.F.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 167 KB

english, 2005

35

Spatiotemporal regulation of the Pak1 kinase

Parrini, M.C., Matsuda, M., de Gunzburg, J.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 207 KB

english, 2005

36

Function and regulation of RhoE

Riento, K., Villalonga, P., Garg, R., Ridley, A.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 104 KB

english, 2005

37

Targeting of Rab GTPases to cellular membranes

Ali, B.R., Seabra, M.C.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 209 KB

english, 2005

38

Compartmentalized signalling of Ras

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 288 KB

english, 2005

39

Use of the Ras binding domain of c-Raf for biochemical and live-cell analysis of Ras activation: Figure 1

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 81 KB

english, 2005

40

Studying the consequences of immediate loss of gene function in the intestine: APC

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 52 KB

english, 2005

41

Prospects in NSAID-derived chemoprevention of colorectal cancer

Chell, S., Patsos, H.A., Qualtrough, D., H-Zadeh, A.M., Hicks, D.J., Kaidi, A., Witherden, I.R., Williams, A.C., Paraskeva, C.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 198 KB

english, 2005

42

The role of the retinoblastoma protein (Rb) in the nuclear localization of BAG-1: implications for colorectal tumour cell survival

Clemo, N.K., Arhel, N.J., Barnes, J.D., Baker, J., Moorghen, M., Packham, G.K., Paraskeva, C., Williams, A.C.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 302 KB

english, 2005

43

Functional consequences of DNA mismatch repair missense mutations in murine models and their impact on cancer predisposition

Scherer, S.J., Avdievich, E., Edelmann, W.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 168 KB

english, 2005

44

Relationship between the role of the adenomatous polyposis coli protein in colon cancer and its contribution to cytoskeletal regulation: Figure 1

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 128 KB

english, 2005

45

Pro-inflammatory mediator leukotriene D 4 induces transcriptional activity of potentially oncogenic genes: Figure 1

Mezhybovska, M., Wikström, K., Öhd, J.F., Sjölander, A.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 146 KB

english, 2005

46

Molecular targets of nitric-oxide-donating aspirin in cancer

Kashfi, K., Rigas, B.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 199 KB

english, 2005

47

Design of a MUC1-based cancer vaccine

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 157 KB

english, 2005

48

Methylation of the ESR1 CpG island in the colorectal mucosa is an ‘all or nothing’ process in healthy human colon, and is accelerated by dietary folate supplementation in the mouse

Belshaw, N.J., Elliott, G.O., Williams, E.A., Mathers, J.C., Buckley, L., Bahari, B., Johnson, I.T.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 347 KB

english, 2005

49

DNA damage hypersensitivity in cells lacking BRCA2 : a review of in vitro and in vivo data

Hay, T., Clarke, A.R.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 106 KB

english, 2005

50

Action of a library of O-glycosylation inhibitors on the growth of human colorectal cancer cells in culture

Patsos, G., Hebbe-Viton, V., San Martin, R., Paraskeva, C., Gallagher, T., Corfield, A.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 97 KB

english, 2005

51

Is COX-2 a ‘collateral’ target in cancer prevention?

Kashfi, K., Rigas, B.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 137 KB

english, 2005

52

DNA mismatch repair status may influence anti-neoplastic effects of butyrate

Coxhead, J.M., Williams, E.A., Mathers, J.C.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 59 KB

english, 2005

53

DMBT1 expression and glycosylation during the adenoma–carcinoma sequence in colorectal cancer: Figure 1

Robbe, C., Paraskeva, C., Mollenhauer, J., Michalski, J.C., Sergi, C., Corfield, A.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 95 KB

english, 2005

54

The importance of colonic butyrate transport to the regulation of genes associated with colonic tissue homoeostasis

Daly, K., Cuff, M.A., Fung, F., Shirazi-Beechey, S.P.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 70 KB

english, 2005

55

Regulation of tetrapyrrole biosynthesis in higher plants

Moulin, M., Smith, A.G.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 305 KB

english, 2005

56

Pantothenate biosynthesis in higher plants

Coxon, K.M., Chakauya, E., Ottenhof, H.H., Whitney, H.M., Blundell, T.L., Abell, C., Smith, A.G.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 178 KB

english, 2005

57

Flavoenzyme catalysed oxidation of amines: roles for flavin and protein-based radicals

Rigby, S.E., Basran, J., Combe, J.P., Mohsen, A.W., Toogood, H., van Thiel, A., Sutcliffe, M.J., Leys, D., Munro, A.W., Scrutton, N.S.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 181 KB

english, 2005

58

Tetrahydrofolate biosynthesis and distribution in higher plants

Sahr, T., Ravanel, S., Rébeillé, F.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 297 KB

english, 2005

59

Mechanistic and inhibition studies of chorismate-utilizing enzymes

Kerbarh, O., Bulloch, E.M.M., Payne, R.J., Sahr, T., Rébeillé, F., Abell, C.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 244 KB

english, 2005

60

Biophysical tools to monitor enzyme–ligand interactions of enzymes involved in vitamin biosynthesis

Ciulli, A., Abell, C.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 206 KB

english, 2005

61

Studies on thiamine diphosphate-dependent enzymes

Leeper, F.J., Hawksley, D., Mann, S., Perez Melero, C., Wood, M.D.H.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 219 KB

english, 2005

62

Crystal structure of DMGO provides a prototype for a new tetrahydrofolate-binding fold

Scrutton, N.S., Leys, D.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 323 KB

english, 2005

63

Structures and reaction mechanisms of riboflavin synthases of eubacterial and archaeal origin

Fischer, M., Römisch, W., Illarionov, B., Eisenreich, W., Bacher, A.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 337 KB

english, 2005

64

Isoprenoid biosynthetic pathways as anti-infective drug targets

Rohdich, F., Bacher, A., Eisenreich, W.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 277 KB

english, 2005

65

Covalent cofactor attachment to proteins: cytochrome c biogenesis

Stevens, J.M., Uchida, T., Daltrop, O., Ferguson, S.J.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 77 KB

english, 2005

66

Inhibition of 7,8-diaminopelargonic acid aminotransferase by amiclenomycin and analogues

Mann, S., Marquet, A., Ploux, O.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 201 KB

english, 2005

67

Anaerobic synthesis of vitamin B 12 : characterization of the early steps in the pathway

Frank, S., Brindley, A.A., Deery, E., Heathcote, P., Lawrence, A.D., Leech, H.K., Pickersgill, R.W., Warren, M.J.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 241 KB

english, 2005

68

Aerobic synthesis of vitamin B 12 : ring contraction and cobalt chelation

Heldt, D., Lawrence, A.D., Lindenmeyer, M., Deery, E., Heathcote, P., Rigby, S.E., Warren, M.J.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 471 KB

english, 2005

69

Biotin synthase mechanism: an overview

Lotierzo, M., Tse Sum Bui, B., Florentin, D., Escalettes, F., Marquet, A.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 176 KB

english, 2005

70

Molecular and thermodynamic bioenergetics

Williams, R.J.P.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 231 KB

english, 2005

71

Is a third proton-conducting pathway operative in bacterial cytochrome c oxidase?: Figure 1

Salje, J., Ludwig, B., Richter, O.-M.H.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 114 KB

english, 2005

72

Terminal oxidases of cyanobacteria

Hart, S.E., Schlarb-Ridley, B.G., Bendall, D.S., Howe, C.J.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 89 KB

english, 2005

73

Ion translocation by the Escherichia coli NADH:ubiquinone oxidoreductase (complex I)

Friedrich, T., Stolpe, S., Schneider, D., Barquera, B., Hellwig, P.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 154 KB

english, 2005

74

Structure–function relationships in mitochondrial complex I of the strictly aerobic yeast Yarrowia lipolytica

Brandt, U., Abdrakhmanova, A., Zickermann, V., Galkin, A., Dröse, S., Zwicker, K., Kerscher, S.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 325 KB

english, 2005

75

Ubiquinone reduction in the photosynthetic reaction centre of Rhodobacter sphaeroides : interplay between electron transfer, proton binding and flips of the quinone ring

Mulkidjanian, A.Y., Kozlova, M.A., Cherepanov, D.A.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 515 KB

english, 2005

76

Role of electron-transfer quenching of chlorophyll fluorescence by carotenoids in non-photochemical quenching of green plants

Dreuw, A., Fleming, G.R., Head-Gordon, M.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 228 KB

english, 2005

77

Channelrhodopsins: directly light-gated cation channels

Nagel, G., Szellas, T., Kateriya, S., Adeishvili, N., Hegemann, P., Bamberg, E.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 543 KB

english, 2005

78

Active membrane transport and receptor proteins from bacteria

Saidijam, M., Bettaney, K.E., Szakonyi, G., Psakis, G., Shibayama, K., Suzuki, S., Clough, J.L., Blessie, V., Abu-bakr, A., Baumberg, S., Meuller, J., Hoyle, C.K., Palmer, S.L., Butaye, P., Walravens,

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 329 KB

english, 2005

79

NMR and fluorescence spectroscopy approaches to secondary and primary active multidrug efflux pumps

Lorch, M., Lehner, I., Siarheyeva, A., Basting, D., Pfleger, N., Manolikas, T., Glaubitz, C.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 219 KB

english, 2005

80

Subunit movement in individual H + -ATP synthases during ATP synthesis and hydrolysis revealed by fluorescence resonance energy transfer

Börsch, M., Gräber, P.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 286 KB

english, 2005

81

Structural features and nucleotide-binding capability of the C subunit are integral to the regulation of the eukaryotic V 1 V o ATPases

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 118 KB

english, 2005