Volume 9; Issue 1

Bioorganic & Medicinal Chemistry

Volume 9; Issue 1

1

Antioxidant constituents from rhubarb: structural requirements of stilbenes for the activity and structures of two new anthraquinone glucosides

Hisashi Matsuda, Toshio Morikawa, Iwao Toguchida, Ji-Young Park, Shoichi Harima, Masayuki Yoshikawa

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 265 KB

english, 2001

2

N-(3-acyloxy-2-benzylpropyl)-N′-(4-hydroxy-3-methoxybenzyl)thiourea derivatives as potent vanilloid receptor agonists and analgesics

Jeewoo Lee, Jiyoun Lee, Jiyoung Kim, Soo Yeon Kim, Moon Woo Chun, Hawon Cho, Sun Wook Hwang, Uhtaek Oh, Young Ho Park, Victor E Marquez, Maryam Beheshti, Tamas Szabo, Peter M Blumberg

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 394 KB

english, 2001

3

Synthesis and stereostructure–activity relationship of three asymmetric center pyrethroids: 2-methyl-3-phenylcyclopropyl-methyl 3-phenoxybenzyl ether and cyanohydrin ester

Yoshinori Nishii, Nobuo Maruyama, Kazunori Wakasugi, Yoo Tanabe

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 212 KB

english, 2001

4

Chemical synthesis and biological investigation of a 77-mer oligoribonucleotide with a sequence corresponding to E. coli tRNAAsp

Tina Persson, Ursula Kutzke, Silke Busch, Rita Held, Roland K Hartmann

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 185 KB

english, 2001

5

Alternative heterocycles for DNA recognition: an N-methylpyrazole/N-methylpyrrole pair specifies for AT/TA base pairs

Doan H. Nguyen, Jason W. Szewczyk, Eldon E. Baird, Peter B. Dervan

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 734 KB

english, 2001

6

Participation of the β-hydroxyketone part for potent cytotoxicity of callystatin A, a spongean polyketide

Nobutoshi Murakami, Masanori Sugimoto, Motomasa Kobayashi

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 287 KB

english, 2001

7

Synthesis and cytotoxicity of 4′-C- and 5′-C-substituted toyocamycins

Esmir Gunic, Jean-Luc Girardet, Zbigniew Pietrzkowski, Cathey Esler, Guangyi Wang

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 228 KB

english, 2001

8

N-Nitrosoanilines: a new class of caspase-3 inhibitors

Zhengmao Guo, Ming Xian, Wei Zhang, Andrea McGill, Peng George Wang

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 220 KB

english, 2001

9

Molecular determinants of non-specific recognition of δ, μ, and κ opioid receptors

Marta Filizola, Hugo O Villar, Gilda H Loew

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 603 KB

english, 2001

10

Design and synthesis of a multivalent homing device for targeting to murine CD22

Leo A.J.M. Sliedregt, Sabine M.W. van Rossenberg, Reshma Autar, A.Rob P.M. Valentijn, Gijs A. van der Marel, Jacques H. van Boom, Christina Piperi, P. Anton van der Merwe, Johan Kuiper, Theo J.C. van

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 388 KB

english, 2001

11

New constituents and antiplatelet aggregation and anti-HIV principles of Artemisia capillaris

Tian-Shung Wu, Zhih-Jing Tsang, Pei-Lin Wu, Fu-Wen Lin, Chia-Yin Li, Che-Ming Teng, Kuo-Hsiung Lee

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 164 KB

english, 2001

12

Triarylpyrazoles with basic side chains: development of pyrazole-based estrogen receptor antagonists

Shaun R Stauffer, Ying R Huang, Zachary D Aron, Christopher J Coletta, Jun Sun, Benita S Katzenellenbogen, John A Katzenellenbogen

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 414 KB

english, 2001

13

A phosphatidylinositol 3,4,5-trisphosphate analogue with low serum protein-binding affinity

Da-Sheng Wang, Ao-Lin Hsu, Ching-Shih Chen

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 236 KB

english, 2001

14

Estrogen pyrazoles: defining the pyrazole core structure and the orientation of substituents in the ligand binding pocket of the estrogen receptor

Shaun R Stauffer, Ying Huang, Christopher J Coletta, Rosanna Tedesco, John A Katzenellenbogen

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 324 KB

english, 2001

15

2,4-Disubstituted oxazoles and thiazoles as latent pharmacophores for diacylhydrazine of SC-51089, a potent PGE2 antagonist

E.Ann Hallinan, Timothy J. Hagen, Sofya Tsymbalov, Awilda Stapelfeld, Michael A. Savage

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 191 KB

english, 2001

16

Synthesis and characterization of a tetranucleotide analogue containing alternating phosphonate-amide backbone linkages

Peilin Yu, Wei Wang, Hua Zhang, Xueyong Yang, T.Chyau Liang, Xiaolian Gao

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 406 KB

english, 2001

17

Specific inhibitor of puromycin-sensitive aminopeptidase with a homophthalimide skeleton: identification of the target molecule and a structure–activity relationship study

Masato Komoda, Hiroki Kakuta, Hiroyasu Takahashi, Yasuyuki Fujimoto, Shizuo Kadoya, Fuminori Kato, Yuichi Hashimoto

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 397 KB

english, 2001

18

Synthesis and bioactivity of 2,4-diacyl analogues of paclitaxel

Mahendra D Chordia, Haiqing Yuan, Prakash G Jagtap, John F Kadow, Byron H Long, Craig R Fairchild, Kathy A Johnston, David G.I Kingston

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 262 KB

english, 2001

19

Iantherans A and B, unique dimeric polybrominated benzofurans as Na,K-ATPase inhibitors from a marine sponge, Ianthella sp.

Yoshihiro Okamoto, Makoto Ojika, Shingo Suzuki, Masahiro Murakami, Youji Sakagami

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 202 KB

english, 2001

20

N-(Hydroxyaminocarbonyl)phenylalanine: a novel class of inhibitor for carboxypeptidase A

Sang J. Chung, Dong H. Kim

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 165 KB

english, 2001

21

Enzyme-catalyzed prodrug approaches for the histamine H3-receptor agonist (R)-α-methylhistamine

Holger Stark, Michael Krause, Agnès Rouleau, Monique Garbarg, Jean-Charles Schwartz, Walter Schunack

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 220 KB

english, 2001

22

Mechanism of toxicity of esters of Caffeic and dihydrocaffeic acids

Beth Etzenhouser, Corwin Hansch, Sanjay Kapur, C.Dias Selassie

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 212 KB

english, 2001

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