Volume 25; Issue 24

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Bioorganic & Medicinal Chemistry Letters
Volume 25; Issue 24

Bioorganic & Medicinal Chemistry Letters

Volume 25; Issue 24

1

Synthesis, in vitro, and in vivo evaluation of novel functionalized quaternary ammonium curcuminoids as potential anti-cancer agents

Solano, Lucas N., Nelson, Grady L., Ronayne, Conor T., Lueth, Erica A., Foxley, Melissa A., Jonnalagadda, Sravan K., Gurrapu, Shirisha, Mereddy, Venkatram R.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 872 KB

english, 2015

2

Development of surface immobilized 3-azidocoumarin-based fluorogenic probe via strain promoted click chemistry

Bharathi, M. Vijaya, Chhabra, Mohit, Paira, Priyankar

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 1.16 MB

english, 2015

3

Discovery of AZ0108, an orally bioavailable phthalazinone PARP inhibitor that blocks centrosome clustering

Johannes, Jeffrey W., Almeida, Lynsie, Daly, Kevin, Ferguson, Andrew D., Grosskurth, Shaun E., Guan, Huiping, Howard, Tina, Ioannidis, Stephanos, Kazmirski, Steven, Lamb, Michelle L., Larsen, Nicholas

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 880 KB

english, 2015

4

Synthesis of apoptotic chalcone analogues in HepG2 human hepatocellular carcinoma cells

Park, Cheon-Soo, Ahn, Yongchel, Lee, Dahae, Moon, Sung Won, Kim, Ki Hyun, Yamabe, Noriko, Hwang, Gwi Seo, Jang, Hyuk Jai, Lee, Heesu, Kang, Ki Sung, Lee, Jae Wook

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 731 KB

english, 2015

5

Synthesis and biological evaluation of pyrazolopyrimidines as potential antibacterial agents

Goshu, Gashaw M., Ghose, Debarati, Bain, Joy M., Pierce, Phillip G., Begley, Darren W., Hewitt, Stephen N., Udell, Hannah S., Myler, Peter J., Meganathan, R., Hagen, Timothy J.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 2.66 MB

english, 2015

6

Click-based synthesis of bromotyrosine alkaloid analogs as potential anti-biofilm leads for SAR studies

Andjouh, S., Blache, Y.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 1.23 MB

english, 2015

7

Benzo[7]annulene-based GluN2B selective NMDA receptor antagonists: Surprising effect of a nitro group in 2-position

Gawaskar, Sandeep, Schepmann, Dirk, Bonifazi, Alessandro, Robaa, Dina, Sippl, Wolfgang, Wünsch, Bernhard

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 744 KB

english, 2015

8

PPL catalyzed four-component PASE synthesis of 5-monosubstituted barbiturates: Structure and pharmacological properties

Bihani, Manisha, Bora, Pranjal P., Verma, Alakesh K., Baruah, Reshita, Boruah, Hari Prasanna Deka, Bez, Ghanashyam

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 859 KB

english, 2015

9

Design, synthesis, and fungicidal activities of imino diacid analogs of valine amide fungicides

Sun, Man, Yang, Hui-Hui, Tian, Lei, Li, Jian-Qiang, Zhao, Wei-Guang

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 415 KB

english, 2015

10

A new cerebroside from the fruiting bodies of Hericium erinaceus and its applicability to cancer treatment

Lee, Seoung Rak, Jung, Kiwon, Noh, Hyung Jun, Park, Yong Joo, Lee, Hye Lim, Lee, Kang Ro, Kang, Ki Sung, Kim, Ki Hyun

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 728 KB

english, 2015

11

1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as potent GR antagonists with reduced hERG inhibition and an improved pharmacokinetic profile

Hunt, Hazel J., Belanoff, Joseph K., Golding, Emily, Gourdet, Benoit, Phillips, Timothy, Swift, Denise, Thomas, Jennifer, Unitt, John F., Walters, Iain

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 933 KB

english, 2015

12

Identification, synthesis and pharmacological evaluation of novel anti-EV71 agents via cyclophilin A inhibition

Yan, Wenzhong, Qing, Jie, Mei, Hanbing, Nong, Junxiu, Huang, Jin, Zhu, Jin, Jiang, Hualiang, Liu, Lei, Zhang, Linqi, Li, Jian

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 1.09 MB

english, 2015

13

Selective oxidation of 5-hydroxymethylcytosine with micelle incarcerated oxidants to determine it at single base resolution

Fukuzawa, Seketsu, Tachibana, Kazuo, Tajima, Shoji, Suetake, Isao

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 1.92 MB

english, 2015

14

2,3′-Bis(1′H-indole) heterocycles: New p53/MDM2/MDMX antagonists

Neochoritis, Constantinos G., Wang, Kan, Estrada-Ortiz, Natalia, Herdtweck, Eberhardt, Kubica, Katarzyna, Twarda, Aleksandra, Zak, Krzysztof M., Holak, Tad A., Dömling, Alexander

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 1.42 MB

english, 2015

15

Discovery of novel 2-benzylisoquinolin-1(2H)-ones as potent vasodilative agents

Kang, Bo-Rui, Li, Sen, Mao, Shuai, Cao, Yong-Xiao, Zhang, San-Qi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 757 KB

english, 2015

16

Litomosoides sigmodontis: A jird urine metabolome study

Globisch, Daniel, Specht, Sabine, Pfarr, Kenneth M., Eubanks, Lisa M., Hoerauf, Achim, Janda, Kim D.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 739 KB

english, 2015

17

Divinyl BODIPY derivative: Synthesis, photophysical properties, crystal structure, photostability and bioimaging

Yang, Liutao, Liu, Ying, Liu, Wei, Ma, Chunping, Zhang, Chun, Li, Yang

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 501 KB

english, 2015

18

Charge-switching amino acids-based cationic lipids for efficient gene delivery

Zheng, Li-Ting, Yi, Wen-Jing, Liu, Qiang, Su, Rong-Chuan, Zhao, Zhi-Gang

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 2.09 MB

english, 2015

19

Novel orally active inhibitors of β-1,3-glucan synthesis derived from enfumafungin

Apgar, James M., Wilkening, Robert R., Greenlee, Mark L., Balkovec, James M., Flattery, Amy M., Abruzzo, George K., Galgoci, Andrew M., Giacobbe, Robert A., Gill, Charles J., Hsu, Ming Jo, Liberator,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 1.13 MB

english, 2015

20

Structural measurements and cell line studies of the copper–PEG–Amikacin complex against Mycobacterium tuberculosis

Manning, Thomas, Patel, Hatel, Wylie, Greg, Phillips, Dennis, Jarvis, Jackie

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 1.12 MB

english, 2015

21

Graphical contents list

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 2.82 MB

english, 2015

22

Editorial board

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 31 KB

english, 2015

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