Volume 26; Issue 22

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Bioorganic & Medicinal Chemistry Letters
Volume 26; Issue 22

Bioorganic & Medicinal Chemistry Letters

Volume 26; Issue 22

1

MiR-106a: Promising biomarker for cancer

Pan, Yao-Jie, Zhuang, Ying, Zheng, Jun-Nian, Pei, Dong-Sheng

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 502 KB

english, 2016

2

5-Aminopyrazole-4-carboxamide analogues are selective inhibitors of Plasmodium falciparum microgametocyte exflagellation and potential malaria transmission blocking agents

Huang, Wenlin, Hulverson, Matthew A., Zhang, Zhongsheng, Choi, Ryan, Hart, Kevin J., Kennedy, Mark, Vidadala, Rama Subba Rao, Maly, Dustin J., Van Voorhis, Wesley C., Lindner, Scott E., Fan, Erkang, O

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 2.57 MB

english, 2016

3

The synthesis and antistaphylococcal activity of dehydroabietic acid derivatives: Modifications at C-12

Liu, Ming-Liang, Pan, Xue-Ying, Yang, Teng, Zhang, Wen-Ming, Wang, Tian-Qi, Wang, He-Yun, Lin, Hai-Xia, Yang, Cai-Guang, Cui, Yong-Mei

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 5.49 MB

english, 2016

4

Identification of the minimum PAR4 inhibitor pharmacophore and optimization of a series of 2-methoxy-6-arylimidazo[2,1-b][1,3,4]thiadiazoles

Temple, Kayla J., Duvernay, Matthew T., Maeng, Jae G., Blobaum, Anna L., Stauffer, Shaun R., Hamm, Heidi E., Lindsley, Craig W.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 1.23 MB

english, 2016

5

Variation of the aryl substituent on the piperazine ring within the 4-(piperazin-1-yl)-2,6-di(pyrrolidin-1-yl)pyrimidine scaffold unveils potent, non-competitive inhibitors of the inflammatory caspases

Kent, Courtney R., Bryja, Magdalena, Gustafson, Helen A., Kawarski, Margaret Y., Lenti, Gena, Pierce, Emily N., Knopp, Rachel C., Ceja, Victor, Pati, Bhabna, Walters, D. Eric, Karver, Caitlin E.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 1.70 MB

english, 2016

6

A two-step strategy to radiolabel choline phospholipids with 99mTc in S180 cell membranes via strain-promoted cyclooctyne–azide cycloaddition reaction

Chen, Qingxin, Chu, Taiwei

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 398 KB

english, 2016

7

Dihydrostilbenes and diarylpropanes: Synthesis and in vitro pharmacological evaluation as potent nitric oxide production inhibition agents

Jang, Ha Young, Park, Hyeong Jin, Damodar, Kongara, Kim, Jin-Kyung, Jun, Jong-Gab

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 756 KB

english, 2016

8

I. Discovery of a novel series of CXCR3 antagonists. Multiparametric optimization of N,N-disubstituted benzylamines

Bata, Imre, Tömösközi, Zsuzsanna, Buzder-Lantos, Péter, Vasas, Attila, Szeleczky, Gábor, Bátori, Sándor, Barta-Bodor, Veronika, Balázs, László, Ferenczy, György G.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 6.77 MB

english, 2016

9

II. Discovery of a novel series of CXCR3 antagonists with a beta amino acid core

Bata, Imre, Tömösközi, Zsuzsanna, Buzder-Lantos, Péter, Vasas, Attila, Szeleczky, Gábor, Balázs, László, Barta-Bodor, Veronika, Ferenczy, György G.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 2.85 MB

english, 2016

10

Metabolism-based structure optimization: Discovery of a potent and orally available tyrosine kinase ALK inhibitor bearing the tetracyclic benzo[b]carbazolone core

Han, Mei, Wang, Chengyan, Ji, Yinchun, Song, Zilan, Xing, Li, Su, Yi, Wang, Xisheng, Zhang, Ao, Ai, Jing, Geng, Meiyu

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 832 KB

english, 2016

11

Editorial board

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 30 KB

english, 2016

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