Volume 4; Issue 11

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Bioorganic & Medicinal Chemistry Letters
Volume 4; Issue 11

Bioorganic & Medicinal Chemistry Letters

Volume 4; Issue 11

1

Graphical abstracts

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 584 KB

english, 1994

2

Peptoid mimics of a C2-symmetric inhibitor of the HIV-1 protease.

Jean-Paul Mazaleyrat, Isabelle Rage, Abdel Malek Mouna, Jaroslav Šavrda, Michel Wakselman, Raymond Boulay, Yves Lelièvre

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 348 KB

english, 1994

3

Benzopyran potassium channel activators related to cromakalim - heterocyclic amide replacements at position 4.

Gordon Burrell, John M. Evans, Michael S. Hadley, Frances Hicks, Geoffrey Stemp

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 435 KB

english, 1994

4

The identification of a novel renin inhibitor of equivalent efficacy following oral or intravenous administration.

S.A. Smith, K.A. Al-Barazanji, R.E. Buckingham, F. Cassidy, M.C. Coldwell, F.J.L. Finney, M.S. Hadley, P. Ham, S.A. Lawrence, D.J. Nash, E.J.R. Tingley, J.M. Watson

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 439 KB

english, 1994

5

Bisindolylmaleimide inhibitors of protein kinase C. Further conformational restriction of a tertiary amine side chain.

Peter D. Davis, Trevor J. Hallam, William Harris, Christopher H. Hill, Geoffrey Lawton, John S. Nixon, Janet L. Smith, David R. Vesey, Sandra E. Wilkinson

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 407 KB

english, 1994

6

Design and synthesis of 6-fluoropurine acyclonucleosides : potential prodrugs of acyclovir and ganciclovir

Dae-Kee Kim, Hee-Kap Kim, Young-Bok Chae

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 325 KB

english, 1994

7

Inhibition of oxidosqualene cyclase by substituted quinolizidines

Angela L. Marquart, Gerald L. Schatzman, Norton P. Peet, William R. Moore, Edward W. Huber, Steven L. Gallion, Michael R. Angelastro

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 167 KB

english, 1994

8

Cucurbitacin F derivatives, anti-HIV principles from cowania mexicana

Takao Konoshima, Yoshiki Kashiwada, Midori Takasaki, Mutsuo Kozuka, Ichiro Yasuda, L.Mark Cosentino, Kuo-Hsiung Lee

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 250 KB

english, 1994

9

Anti-allergy agents. 3. Angular tricyclic ether derivatives of the 1,8-naphthyridin-2(1H)-one ring system

David J. Blythin, Ho-Jane Shue, Emilie Carlon, James Spitler, William Kreutner

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 522 KB

english, 1994

10

Indolocarbazole nitrogens linked by three-atom bridges: a potent new class of PKC inhibitors

Susan F. Vice, W.Robert Bishop, Stuart W. McCombie, Huong Dao, Emily Frank, Ashit K. Ganguly

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 494 KB

english, 1994

11

A convenient procedure for the deprotection of silylated nucleosides and nucleotides using triethylamine trihydrofluoride

Michael C. Pirrung, Steven W. Shuey, Davic C. Lever, Lara Fallon

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 156 KB

english, 1994

12

Potent, acid-stable and orally active macrolide-type motilin receptor agonists, GM-611 and the derivatives

Hiroshi Koga, Tsutomu Sato, Koichi Tsuzuki, Harumi Onoda, Hitoshi Kuboniwa, Hisanori Takanashi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 442 KB

english, 1994

13

The selenium mediated de-iodination of iodophenols: a model for the mechanism of 5′ thyronine de-iodinase.

Christine Beck, Svend B. Jensen, John Reglinski

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 321 KB

english, 1994

14

Preparative chiral HPLC separation of all possible stereoisomers of LY191704 and LY266111 and their in vitro inhibition of human types 1 and 2 steroid 5α-reductases

Andrew D. Abell, Karl F. Erhard, Hwa-Kwo Yen, Dennis S. Yamashita, Martin Brandt, Hadiza Mohammed, Mark A. Levy, Dennis A. Holt

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 395 KB

english, 1994

15

Conformationally constrained analogues of dag .8. Changes in PK-C binding affinity produced by isosteric groups of the 3-O-acyl function in 2-deoxy-L-ribonolactones

Jeewoo Lee, Rajiv Sharma, Kelly Teng, Nancy E. Lewin, Peter M. Blumberg, Victor E. Marquez

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 539 KB

english, 1994

16

Heteroaromatic Taxol Analogues: The Chemistry and Biological Activities of 3′-Furyl and 3′-Pyridyl Substituted Taxanes

Gunda I. Georg, Gerlandine C.B. Harriman, Michael Hepperle, Richard H. Himes

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 384 KB

english, 1994

17

New dipeptide isosteres useful for the inhibition of HIV-1 protease

Stephen W. Kaldor, Maryls Hammond, Bruce A. Dressman, James E. Fritz, Thomas A. Crowell, Robert A. Hermann

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 425 KB

english, 1994

18

D-amino acids as novel P2/P3 ligands for inhibitors of HIV-1 protease

Timothy A. Shepherd, Louis N. Jungheim, Angela J. Baxter

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 369 KB

english, 1994

19

Design and synthesis of a prototype model antagonist of tachykinin NK-2 receptor

Stephen Hanessian, Baptiste Ronan, Abdel Laoui

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 480 KB

english, 1994

20

(6-oxo-3-pyridazinyl)-benzimidazoles as potent angiotensin II receptor antagonists

Dieter Dorsch, Werner W.K.R. Mederski, Norbert Beier, Inge Lues, Klaus-Otto Minck, Pierre Schelling

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 439 KB

english, 1994

21

The synthesis of 2,2,24- trisubstituted oxetanes as new azole antifungal agents

Dinanath F. Rane, Viyyoor M. Girijavallabhan, Mohindar S. Puar, Anil K. Saksena, David Loebenberg, Raolo M. Parmegiani

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 433 KB

english, 1994

22

Synthesis and pharmacological characterization of ABT-200: a putative novel antidepressant combining potent α-2 antagonism with moderate NE uptake inhibition

Robert E. Zelle, Arthur A. Hancock, Steven A. Buckner, Fatima Z. Basha, Karin Tietje, John F. DeBernardis, Michael D. Meyer

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 354 KB

english, 1994

23

The role of oxygen in the photoinduced antiviral activity of hypericin

M.J. Fehr, S.L. Carpenter, J.W. Petrich

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 512 KB

english, 1994

24

The structure of methimazole and its consequences for current therapeutic models of graves' disease.

Mark Garner, David R. Armstrong, John Reglinski, W.Ewen. Smith, Rhoda Wilson, James H. McKillop

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 397 KB

english, 1994

25

Adamantane and Nipecotic Acid Derivatives as Novel β-Turn Mimics

William J. Hoekstra, Jeffery B. Press, Mary Pat Bonner, Patricia Andrade-Gordon, Patricia M. Keane, Kathleen A. Durkin, Dennis C. Liotta, Kevin H. Mayo

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 334 KB

english, 1994

26

Synthesis of β-estradiol-3-benzoate-17-(succinyl-12A-tetracycline): A potential bone-seeking estrogen

Mark W. Orme, Virender M. Labroo

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 429 KB

english, 1994