Volume 4; Issue 18

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Bioorganic & Medicinal Chemistry Letters
Volume 4; Issue 18

Bioorganic & Medicinal Chemistry Letters

Volume 4; Issue 18

1

Graphical abstracts

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 345 KB

english, 1994

2

Synthesis of novel monocyclic squalestatin analogues as potential inhibitors of squalene synthase

Rupert E. Shaw, Colin Burgess, Richard P.C. Cousins, Gerard M.P. Giblin, David G.H. Livermore, Anthony H. Shingler, Colin Smith, Peter M. Youds

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 417 KB

english, 1994

3

Acyclic NK1 antagonists: Replacements for the benzhydryl group.

C.J. Swain, M.A. Cascieri, A. Owens, W. Saari, S. Sadowski, C. Strader, M. Teall, M.B. Van Niel, B.J. Williams

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 212 KB

english, 1994

4

Argatroban analogs: Synthesis, thrombin inhibitory activity and cell permeability of aminoheterocyclic guanidine surrogates

Raj N. Misra, Yolanda F. Kelly, Bärbel R. Brown, Daniel G.M. Roberts, Saeho Chong, Steven M. Seiler

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 406 KB

english, 1994

5

Facile deprotection of silyl nucleosides with potassium fluoride/ 18-crown-6

Jonathan N. Kremsky, Nanda D. Sinha

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 225 KB

english, 1994

6

Examination of peptidic α′,β-diamino-α,α-difluoroketones as inhibitors of human leukocyte elastase

Peter R. Bernstein, B.J. Kosmider, E.P. Vacek, C.A. Veale, B.C. Gomes

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 266 KB

english, 1994

7

Novel non-squalenoid photoaffinity labels for mammalian squalene epoxidase

Marco Ceruso, Glenn D. Prestwich

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 324 KB

english, 1994

8

Phenytoin derivatives as potent σ ligands

Robert L. Hudkins, Diane L. DeHaven-Hudkins

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 239 KB

english, 1994

9

1-Methylguanosine substitutions of the conserved guanosine residues inactive the hammerhead ribozyme

Stacey Limauro, Fritz Benseler, Larry W. McLaughlin

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 351 KB

english, 1994

10

Dual metalloprotease inhibitors. IV. Utilization of thiazepines and thiazines as constrained peptidomimetic surrogates in mercaptoacyl dipeptides

Jagabandhu Das, Jeffrey A. Robl, Joyce A. Reid, Chong-Qing Sun, Raj N. Misra, Baerbel R. Brown, Denis E. Ryono, Magdi M. Asaad, J.Eileen Bird, Nick C. Trippodo, Edward W. Petrillo, Donald S. Karanewsk

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 425 KB

english, 1994

11

Novel conformationally constrained HIV-1 protease inhibitors: rational design, enzyme inhibition, and X-ray structure of an enzyme-inhibtor complex

B.Moon Kim, Joseph P. Vacca, Paula M.D. Fitzgerald, Paul L. Darke, M.Katharine Holloway, James P. Guare, Colleen M. Hanifin, Deborah J. Arford-Bickerstaff, Joan A. Zugay, Jenny M. Wai, Paul S. Anderso

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 2.01 MB

english, 1994

12

Synthesis and structure activity relationships of alkyl substituted analogues of the functional M1 selective muscarinic receptor agonist xanomeline

Steven J. Quimby, Harlan E. Shannon, Frank P. Bymaster, Per Sauerberg, Preben H Olesen, Malcolm J. Sheardown, Peter D. Suzdak, Charles H. Mitch

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 388 KB

english, 1994

13

A comparative molecular field analysis derived model of the binding of taxol® analogues to microtubules

Karl-Heinz A. Czaplinski, Gary L. Grunewald

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 2.73 MB

english, 1994

14

Design, synthesis, and activity of conformationally-constrained macrocyclic peptide-based inhibitors of HIV protease

Roger A. Smith, Peter J. Coles, Jian Jeffrey Chen, Valerie J. Robinson, I.David MacDonald, Julie Carrière, Allen Krantz

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 454 KB

english, 1994

15

Taxol® structure-activity relationships: synthesis and biological evaluation of taxol analogs modified at C-7

Shu-Hui Chen, Joydeep Kant, Stephen W. Mamber, Gregory P. Roth, Jian-Mei Wei, Dan Marshall, Dolatrai M. Vyas, Vittorio Farina, Annamaria Casazza, Byron H. Long, William C. Rose, Kathy Johnston, Craig

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 433 KB

english, 1994

16

Balanced angiotensin II receptor antagonists. II.1,2 4-aminomethyl- and acylaminomethylimidazoles

Richard E. Olson, Jie Liu, George K. Lalka, Mary K. VanAtten, Ruth R. Wexler, Andrew T. Chiu, Tam T. Nguyen, Dale E. McCall, Pancras C. Wong, Pieter B.M.W.M. Timmermans

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 422 KB

english, 1994

17

Balanced angiotensin II receptor antagonists. III. The effects of substitution at the imidazole 5-position.

Joseph B. Santella III, John V. Duncia, Carol L. Ensinger, Mary K. VanAtten, David J. Carini, Ruth R. Wexler, Andrew T. Chiu, Pancras C. Wong, Pieter B.M.W.M. Timmermans

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 404 KB

english, 1994

18

Synthesis and anti-HCMV activity of 9-[[(ethoxyhydroxyphosphinyl)methoxy]methoxy]guanine, an isostere of PMEG monoethyl ester

Dae-Kee Kim, Young-Woo Kim, Key H. Kim

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 317 KB

english, 1994

19

Synthesis and anti-HIV activity of poly(cysteic acid)

Young-im Oh, Mark Cushman

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 258 KB

english, 1994

20

Benzolactam growth hormone secretagogues: Carboxamides as replacements for the 2′-tetrazole moiety of L-692,429

Robert J. DeVita, William R. Schoen, Michael H. Fisher, Alison J. Frontier, Judith M. Pisano, Matthew J. Wyvratt Jr., Kang Cheng, Wanda W.-S. Chan, Bridget S. Butler, Gerard J. Hickey, Thomas M. Jacks

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 356 KB

english, 1994

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