Volume 4; Issue 19

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Bioorganic & Medicinal Chemistry Letters
Volume 4; Issue 19

Bioorganic & Medicinal Chemistry Letters

Volume 4; Issue 19

1

Methionine replacements in biologically active peptides

David C. Horwell, Paul D. Nichols, Edward Roberts

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 270 KB

english, 1994

2

Pyridine and piperidine derivatives as inhibitors of dihydrodipicolinic acid synthase, a key enzyme in the diaminopimelate pathway to l-lysine

Lynda Couper, John E. McKendrick, David J. Robins, Ewan J.T. Chrystal

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 412 KB

english, 1994

3

A new hydroxyethylamine class of HIV-1 protease inhibitors with high antiviral potency and oral bioavailability

B.Moon Kim, Joseph P. Vacca, James P. Guare, Colleen M. Hanifin, Stuart R. Michelson, PaulL. Darke, Joan A. Zugay, Emilio A. Emini, William Schleif, Jiunn H. Lin, I-Wu Chen, Kari Vastag, Drazen Ostovi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 463 KB

english, 1994

4

Synthesis and biological evaluation of 1-substituted-7-(1-hydroxyethyl) carbacephems - a class of “hybrid” bicyclic β-lactams

Stephen Hanessian, Michael J. Rozema

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 519 KB

english, 1994

5

Synthesis of tricyclic β-lactams - functionally and topologically novel carbacephems

Stephen Hanessian, G.Bhaskar Reddy

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 429 KB

english, 1994

6

β-lactam-recognizing enzymes exhibit different structural specificity in acyclic amide and ester substrates: a starting point in β-lactamase evolution?

Yang Xu, R.F. Pratt

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 478 KB

english, 1994

7

Stereochemical approach for enzyme inhibitor design

Dong H. Kim, Li Zhi-Hong

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 377 KB

english, 1994

8

Total synthesis of novel conduritol related compounds capable of modulating insulin release.

D.C. Billington, F. Perron-Sierra, I. Picard, S. Beaubras, J. Duhault, J. Espinal, S. Challal

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 406 KB

english, 1994

9

A convenient synthesis of 2-amino-2-oxazolines and their pharmacological evaluation at cloned human α adrenergic receptors

Wai C. Wong, Diana Wang, Carlos Forray, Pierre J.-J. Vaysse, Theresa A. Branchek, Charles Gluchowski

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 400 KB

english, 1994

10

A non-steroidal diene acid inhibitor of human type 2 stereoid 5α-reductase

Andrew D. Abell, Martin Brandt, Mark A. Levy, Dennis A. Holt

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 261 KB

english, 1994

11

Synthesis and biology of substituted 3′-phenyl taxol analogues

Gunda I. Georg, Zacharia S. Cheruvallath, Geraldin C.B. Harriman, Michael Hepperle, Haeil Park, Richard H. Himes

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 434 KB

english, 1994

12

Development of angiotensin II antagonists with equipotent affinity for human AT1 and AT2 receptor subtypes.

Tomasz W. Glinka, Stephen E. de Laszlo, Peter K.S. Siegl, Raymond S. Chang, Salah D. Kivlighn, Terry S. Schorn, Kristie A. Faust, Tsing-Bau Chen, Gloria J. Zingaro, Victor J. Lotti, William J. Greenle

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 464 KB

english, 1994

13

Symmetry-based HIV protease inhibitors containing a hydroxy bis-urea isostere

Ramnarayan S. Randad, Rajan H. Naik, Sergei V. Gulnik, Betty Yu, John W. Erickson

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 224 KB

english, 1994

14

Novel ether derivatives of alkyl piperidines as potential sigma / 5HT2 antipsychotic agents

Thomas E. Christos, Gary A. Cain, Alexander L. Johnson, William K. Schmidt, S.William Tam

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 340 KB

english, 1994

15

Synthesis, chemical half-life and decomposition of new N3-(substituted) derivatives of CCNU

Gilles Gallant, Romano Salvador, Hélène Dulude

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 409 KB

english, 1994

16

The synthesis and evaluation of peptidyl aspartyl aldehydes as inhibitors of ice.

Michael D. Mullican, David J. Lauffer, Roger J. Gillespie, Saroop S. Matharu, David Kay, Geoffrey M. Porritt, Phillip L. Evans, Julian M.C. Golec, Mark A. Murcko, Yu-Ping Luong, Scott A. Raybuck, Davi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 306 KB

english, 1994

17

Graphical abstracts

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 377 KB

english, 1994

18

Identification of a fluorescent glucoside isolated from the protein-free extract of human lens

Amane Inoue, Kenshi Satoh

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 247 KB

english, 1994

19

Synthesis and anti-tumour activity of 6-methyl derivatives of flavone-8-acetic acid (FAA)

R.Alan Aitken, Michael C. Bibby, John A. Double, Roger M. Phillips, Shiv Kumar Sharma

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 364 KB

english, 1994

20

On the mechanism of arylamine-DNA adduct formation

Karl A. Werbovetz, Timothy L. Macdonald

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 294 KB

english, 1994

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