Volume 5; Issue 13

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Bioorganic & Medicinal Chemistry Letters
Volume 5; Issue 13

Bioorganic & Medicinal Chemistry Letters

Volume 5; Issue 13

1

Thiourea analogues of resiniferatoxin as ligands for the vanilloid receptor

Jeewoo Lee, Geza Acs, Peter M. Blumberg, Victor E. Marquez

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 189 KB

english, 1995

2

Stereochemistry of the benzodiazepine based Ras farnesyltransferase inhibitors

Thomas E. Rawson, Todd C. Somers, James C. Marsters Jr., Dairian T. Wan, Mark E. Reynolds, Daniel J. Burdick

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 234 KB

english, 1995

3

Isolation and structure of the human cancer cell growth inhibitory cyclic decapeptides phakellistatins 7, 8 and 91,2

George R. Pettit, Jun-ping Xu, Ann-Christine Dorsaz, Michael D. Williams, Michael R. Boyd, Ronald L. Cerny

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 294 KB

english, 1995

4

1,2,3-Trisubstituted cyclohexyl substance P antagonists: significance of the ring nitrogen in piperidine-based NK-1 receptor antagonists

Sander G. Mills, Malcolm MacCoss, Dennis Underwood, Shrenik K. Shah, Paul E. Finke, Daniel J. Miller, Richard J. Budhu, Margaret A. Cascieri, Sharon Sadowski, Catherine D. Strader

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 283 KB

english, 1995

5

Linear peptide ETA antagonists: rational design and practical derivatization of N-terminal amino- and imino-carbonylated tripeptide derivatives

Toshio Nagase, Toshiaki Mase, Takehiro Fukami, Takashi Hayama, Kagari Fujita, Kenji Niiyama, Hirobumi Takahashi, Uno Kumagai, Yuko Urakawa, Yohko Nagasawa, Masaki Ihara, Masaru Nishikibe, Kiyofumi Ish

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 373 KB

english, 1995

6

A regio- and stereoselective synthesis of 4-O-sulfated chondroitin di- and tetrasaccharides based on the strategy designed for the elongation of the repeating unit

Jun-ichi Tamura, Klaus W. Neumann, Tomoya Ogawa

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 226 KB

english, 1995

7

The discovery of CP-96,021 and CP-96,486, balanced, combined, potent and orally active leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor antagonists.

A. Marfat, R. Chambers, J. Cheng, K. Cooper, D. Damon, J. Delehunt, J. Eggler, H. Masamune, L. Melvin, J. Watson

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 343 KB

english, 1995

8

Enantioselective oxidation of 2-methyl-1-alkanols by alcohol oxidase from methylotrophic yeasts

Dawn S. Clark, Shimona Geresh, Robert DiCosimo

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 373 KB

english, 1995

9

Discovery of substituted 8,9-dicarboxyldibenzo [2,3:5,6] bicyclo [5.2.0] nonan-4-ones with moderate binding affinity to the endothelin ETA and ETB receptors

R.A. Rivero, W.J. Greenlee, P.D. Williams, G.R. Kieczykowski, D.L. Williams Jr.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 235 KB

english, 1995

10

Inhibition of interleukin-1β converting enzyme by N-Acyl-aspartic acid ketones

Adnan M.M. Mjalli, Kevin T. Chapman, Justin J. Zhao, Nancy A. Thornberry, Erin P. Peterson, Malcolm MacCoss

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 190 KB

english, 1995

11

CCKB selective receptor ligands: novel 1,3,5-trisubstituted benzazepin-2-ones

Monique B. van Niel, Stephen B. Freedman, Victor G. Matassa, Smita Patel, Roy R. Pengilley, Alison J. Smith

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 298 KB

english, 1995

12

Benzothiazolylthio carbapenems: potent anti-MRSA agents

Sherman T. Waddell, Ronald W. Ratcliffe, Sandra P. Szumiloski, Kenneth J. Wildonger, Robert R. Wilkening, Timothy A. Blizzard, Joann Huber, Joyce Kohler, Karen Dorso, Earl St. Rose, Jon G. Sundelof, G

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 305 KB

english, 1995

13

Contributors to this issue

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 80 KB

english, 1995

14

Graphical abstracts

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 287 KB

english, 1995

15

Synthesis and bioactivity of photolabile sirolimus (rapamycin) analogs

Yanqui Chen, Koji Nakanishi, Diana Merrill, Chee P. Eng, Katherine L. Molnar-Kimber, Amedeo Failli, Thomas J. Caggiano

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 199 KB

english, 1995

16

The SAR of 6-(N-alkyl-N-acyl)-2-propyl-3-[(2′-tetrazol-5-yl)biphen-4-yl)methyl]-quinazolinones as balanced affinity antagonists of the human AT1 and AT2 receptors

Stephen E. de Laszlo, Raymond S. Chang, Tsing-Bau Chen, Kristie A. Faust, William J. Greenlee, Salah D. Kivlighn, Victor J. Lotti, Stacey S. O'Malley, Terry W. Schorn, Terry W. Schorn, Peter K. Siegl,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 380 KB

english, 1995

17

Synthesis and pharmacological profile of two novel heterocyclic chromanols, CP-80,798 and CP-85,958, as potent LTD4 receptor antagonists

E.G. Andrews, G.W. Antognoli, R. Breslow, M.P. Carta, T.J. Carty, R.J. Chambers, J.B. Cheng, V.L. Cohan, J.L. Collins, D.B. Damon, J. Delehunt, J.F. Eggler, J.D. Eskra, K.W. Freiert, W.A. Hada, A. Mar

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 298 KB

english, 1995

18

LTD4 Receptor binding activity of novel pyridine chromanols: qualitative correlation with pKa

Hiroko Masamune, James F. Eggler, Anthony Marfat, Lawrence S. Melvin Jr., Frank W. Rusek, Jeanene E. Tickner, John B. Cheng, John T. Shirley

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 256 KB

english, 1995

19

A convenient synthesis of sulfated and sialyl oligosaccharides as potential ligands for CD22 adhesion protein

Rakesh K. Jain, Conrad F. Piskorz, Khushi L. Matta

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 253 KB

english, 1995

20

Inhibition of interleukin-1β converting enzyme by N-acyl-aspartyl aryloxymethyl ketones

Adnan M.M. Mjalli, Justin J. Zhao, Kevin T. Chapman, Nancy A. Thornberry, Erin P. Peterson, Malcolm MacCoss, William K. Hagmann

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 271 KB

english, 1995

21

Novel indolactam-based inhibitors of matrix metalloproteinases

Arlindo L. Castelhano, Roland Billedeau, Nolan Dewdney, Sheila Donnelly, Stephen Horne, Lilia J. Kurz, T.J. Liak, Robert Martin, Rhonda Uppington, Zhengyu Yuan, Allen Krantz

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 343 KB

english, 1995