Volume 6; Issue 20

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Bioorganic & Medicinal Chemistry Letters
Volume 6; Issue 20

Bioorganic & Medicinal Chemistry Letters

Volume 6; Issue 20

1

Syntheses of trans-3′-substituted-CCG-IV analogs and their characterization to ionotropic glutamate receptors

Keiko Shimamoto, Yasushi Shigeri, Terumi Nakajima, Noboru Yumoto, Susumu Yoshikawa, Yasufumi Ohfune

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 335 KB

english, 1996

2

Concerning the thermolability of cholesta-5,8-dien-3β-ol, a sterol that accumulates in blood and tissues in a human genetic developmental disorder

B. Ruan, J. Pang, W.K. Wilson, G.J. Schroepfer Jr.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 236 KB

english, 1996

3

Halogen substitution at the isoxazole ring enhances the activity of N-(isoxazolyl)sulfonamide endothelin antagonists

Ming Fai Chan, B. Raju, Adam Kois, Rosario S. Castillo, Erik J. Verner, Chengde Wu, Emily Hwang, Ilya Okun, Fiona Stavros, V.N. Balaji

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 257 KB

english, 1996

4

D-Phe-Pro-p-Amidinobenzylamine: A potent and highly selective thrombin inhibitor

Michael R. Wiley, Nickolay Y. Chirgadze, David K. Clawson, Trelia J. Craft, Donetta S. Gifford-Moore, Noel D. Jones, Jennifer L. Olkowski, Leonard C. Weir, Gerald F. Smith

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 303 KB

english, 1996

5

New antithrombotic RGD-mimetics with high bioavailability

Joachim Gante, Horst Juraszyk, Peter Raddatz, Hanns Wurziger, Sabine Bernotat-Danielowski, Guido Melzer, Friedrich Rippmann

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 204 KB

english, 1996

6

A rapid synthesis of some 5′-amino- nucleosides and nucleotides as potential antiviral compounds

Christopher McGuigan, Stephen Turner, Naheed Mahmood, Alan J Hay

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 241 KB

english, 1996

7

Synthesis of a highly functionalized rigid template by solid phase azomethine ylide cycloaddition

Andrew J. Bicknell, Nicholas W. Hird

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 183 KB

english, 1996

8

Studies on the structural feature of S'1 subsite of neprilysin (EC.3.4.24.11): Stereochemical requirement for the enzyme-inhibitor docking process

Denis Danvy, Thierry Monteil, Jean-Christophe Plaquevent, Lucette Duhamel, Pierre Duhamel, Claude Gros, Nadine Noël, Jean-Charles Schwartz, Jeanne-Marie Lecomte

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 187 KB

english, 1996

9

Inactivation of a prototypic zinc-containing protease with (s)-2-benzyl-2-(3-oxo-2-isoxazolidinyl)acetic acid

Kyung Joo Lee, Dong H. Kim

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 225 KB

english, 1996

10

Synthesis and antibacterial activity of lipophilic carbapenems with anti-MRSA activity

Jean Claude Arnould, Ruth N Illingworth, Wright W Nichols, R. Geoffrey Wilson

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 326 KB

english, 1996

11

Palladium-catalysed synthesis of some biologically active 5, 6-disubstituted uracils

Palas Das, C.P. Spears, A.H. Shahinian, Swapan K. Dasgupta, Nitya G. Kundu

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 209 KB

english, 1996

12

Trifluoromethyl alcohol and ketone inhibitors of metallo-β-lactamases

Magnus W. Walter, Antonio Felici, Moreno Galleni, Raquel Paul Soto, Robert M. Adlington, Jack E. Baldwin, Jean-Marie Frère, Mikhail Gololobov, Christopher J. Schofield

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 250 KB

english, 1996

13

Synthesis and cytotoxic activity of phenyl-hexahydropyrrolo[3,4-c]carbazoles

Esther Caballero, Francine García, Dolores Grávalos, Manuel Medarde, Heidi Sahagún, Fernando Tomé

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 270 KB

english, 1996

14

Inhibition of HSV-1 protease by benzoxazinones

Richard L. Jarvest, Martin J. Parratt, Christine M. Debouck, Joselina G. Gorniak, L. John Jennings, Halina T. Serafinowska, James E. Strickler

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 215 KB

english, 1996

15

Synthesis and biological activity of 4′-azido- and 4′-trifluoracetamido-3′-chloro-3′-deamino-4′-deoxydaunorubicin

Nectarios Aligiannis, Nicole Pouli, Panagiotis Marakos, Alexios-Leandros Skaltsounis, Stephane Leonce, Alain Pierre, Ghanem Atassi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 239 KB

english, 1996

16

Contributors to this issue

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 72 KB

english, 1996

17

Graphical abstracts

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 331 KB

english, 1996

18

Synthesis and antifungal activity of new azole derivatives containing an oxathiane ring

Hiroshi Miyauchi, Tomoharu Tanio, Naohito Ohashi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 208 KB

english, 1996

19

Solid-phase parallel synthesis applied to lead optimization: Discovery of potent analogues of the GPIIb/IIIa antagonist RWJ-50042

William J. Hoekstra, Bruce E. Maryanoff, Patricia Andrade-Gordon, Judith H. Cohen, Michael J. Costanzo, Bruce P. Damiano, Barbara J. Haertlein, Bruce D. Harris, Jack A. Kauffman, Patricia M. Keane, Da

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 343 KB

english, 1996

20

Adenosine deaminase inhibitors. Synthesis and biological evaluation of chain modified analogs of (+)-EHNA

Palle V.P. Pragnacharyulu, Pei-Jung Lu, Elie Abushanab

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 185 KB

english, 1996

21

7,10-Bis(2-mercapto-2-methyl)propyl-7,10-diazapalmitic acid: a novel, N2S2 ligand for technetium-99m

G.S. Jones Jr., D.R. Elmaleh, H.W. Strauss, A.J. Fischman

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 362 KB

english, 1996

22

Lipophilic bioisosteres of nucleoside triphosphates

Alastair O. Goldring, Ian H. Gilbert, Naheed Mahmood, Jan Balzarini

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 308 KB

english, 1996

23

Isosteres of nucleoside triphosphates

Richard Weaver, Ian H. Gilbert, Naheed Mahmood, Jan Balzarini

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 266 KB

english, 1996

24

Novel, selective mechanism-based inhibitors of the herpes proteases

Ivan L. Pinto, Andrew West, Christine M. Debouck, Anthony G. DiLella, Joselina G. Gorniak, Kevin C. O'Donnell, Daniel J. O'Shannessy, Arunbai Patel, Richard L. Jarvest

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 274 KB

english, 1996

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