Volume 7; Issue 22

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Bioorganic & Medicinal Chemistry Letters
Volume 7; Issue 22

Bioorganic & Medicinal Chemistry Letters

Volume 7; Issue 22

1

Synthesis and anti-thrombin activity of a hexasaccharide corresponding to the binding site of dermatan sulfate to heparin cofactor II

Pascal Bourhis, Françoise Machetto, Philippe Duchaussoy, J.-P Hérault, Jean-Maurice Mallet, J.-M Herbert, Maurice Petitou, Pierre Sinay

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 244 KB

english, 1997

2

First total synthesis of the bone resorption markers deoxypyridinoline and hydroxypyridinoline

Rudolf Waelchli, Ch Beerli, H Meigel, L Révész

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 244 KB

english, 1997

3

Novel pyridazino[4,5-b][1,5]oxazepines and -thiazepines as 5-HT1A receptor ligands

P. Mátyus, I. Varga, E. Zára, A. Mezei, Á. Behr, A. Simay, N. Haider, S. Boros, A. Bakonyi, E. Horváth, K. Horváth

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 377 KB

english, 1997

4

Synthesis of UB-165: A novel nicotinic ligand and anatoxin-a/epibatidine hybrid

Emma Wright, Timothy Gallagher, Christopher G.V. Sharples, Susan Wonnacott

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 220 KB

english, 1997

5

Convergent synthesis of 1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3 (ED-71)

Susumi Hatakeyama, Tatsuhiko Ikeda, Junji Maeyama, Tomoyuki Esumi, Yoshiharu Iwabuchi, Hiroshi Irie, Akira Kawase, Noboru Kubodera

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 170 KB

english, 1997

6

Nucleosides and nucleotides. 171. Thermal and nuclease stabilities of G-quadruplexes consisting of oligodeoxynucleotides containing 5-[N-[2-[N,N-bis(2-amino-ethyl)amino]ethyl]carbamoyl]-2′-deoxyuridine or 5-[N-[3-[N,N-bis(3-aminopropyl)amino]propyl]carbamoyl]-2′-deoxyuridine

Yoshihito Ueno, Mai Mikawa, Akira Matsuda

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 240 KB

english, 1997

7

Synthesis and sar of 4-(1H-benzimidazole-2-carbonyl)piperidines with dual histamine H1/tachykinin NK1 receptor antagonist activity

George D Maynard, Larry D Bratton, John M Kane, Timothy P Burkholder, Braulio Santiago, Kenneth T Stewart, Elizabeth M Kudlacz, Scott A Shatzer, Robert W Knippenberg, Amy M Farrell, Deborah E Logan

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 313 KB

english, 1997

8

Use of CoMFA in validating the conformation used in designing 4-(1H-benzimidazole-2-carbonyl)piperidines with H1/NK1 receptor antagonist activity

Roy J Vaz, George D Maynard, Elizabeth M Kudlacz, Larry D Bratton, John M Kane, Scott A Shatzer, Robert W Knippenberg

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 301 KB

english, 1997

9

7α,11β-Disubstituted estrogens: Probes for the shape of the ligand binding pocket in the estrogen receptor

Rosanna Tedesco, John A. Katzenellenbogen, Elio Napolitano

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 327 KB

english, 1997

10

On the mechanism of chorismate mutases: Revisiting structural requirements for catalysis

Christophe C Galopin, Bruce Ganem

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 121 KB

english, 1997

11

Inhibition of nitric oxide synthase by benzoxazolones

K Shankaran, Karla L Donnelly, Shrenik K Shah, John L Humes, Stephen G Pacholok, Stephan K Grant, Barbara G Green, Malcolm MacCoss

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 263 KB

english, 1997

12

Non-peptide itam mimics as ZAP-70 antagonists

Laszlo Revesz, Ernst Blum, Ute Manning, B.Jachez Demange, Armin Widmer, Jean-François Zuber

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 214 KB

english, 1997

13

Synthesis of trimethylated phosphonium and arsonium analogues of the osmoprotectant glycine betaine; contrasted biological activities in two bacterial species

Vianney Pichereau, Anne Cosquer, Annie-Claude Gaumont, Théophile Bernard

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 263 KB

english, 1997

14

(−)-Phenylahistin: A new mammalian cell cycle inhibitor produced by aspergillus ustus

Kaneo Kanoh, Shinkichi Kohno, Tohru Asari, Takeo Harada, Jun Katada, Michiko Muramatsu, Hiroshi Kawashima, Hirokatsu Sekiya, Isao Uno

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 271 KB

english, 1997

15

Oligonucleotides with (N-thymin-1-ylacetyl) 1-phenylserinol in backbone: Chiral acyclic analogues that form dna triplexes

Vipul S. Rana, Vaijayanti A. Kumar, Krishma N. Ganesh

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 306 KB

english, 1997

16

Simple cis-epoxide-based inhibitors of HIV-1 protease

Andrew D Abell, Deborah A Hoult, Douglas A Bergman, David P Fairlie

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 167 KB

english, 1997

17

Synthesis and structure-activity relationships of novel 3′-Hty-substituted pneumocandins

Regina M Black, James M Balkovec, Karl M Nollstadt, Sarah Dreikorn, Kenneth F Bartizal, George K Abruzzo

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 361 KB

english, 1997

18

Anti-AIDS agents. 291. Anti-HIV activity of modified podophyllotoxin derivatives

Catherine Tung-Ling Lee, Victor Chih-Kuang Lin, Shun-Xiang Zhang, Xiao-Kang Zhu, David VanVliet, Hong Hu, Scott A. Beers, Zhe-Qing Wang, L. Mark Cosentino, Susan L. Morris-Natschke, Kuo-Hsiung Lee

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 226 KB

english, 1997

19

Rapid decomposition of peroxynitrite by manganese porphyrin-antioxidant redox couples

Jinbo Lee, Julianne A. Hunt, John T. Groves

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 367 KB

english, 1997

20

1-Oxo-3-aryl-1H-indene-2-carboxylic acid derivatives as selective inhibitors of fibroblast growth factor receptor-1 tyrosine kinase

M.R. Barvian, R.L. Panek, G.H. Lu, A.J. Kraker, A. Amar, B. Hartl, J.M. Hamby, H.D.H. Showalter

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 270 KB

english, 1997

21

Synthesis of (alkoxycarbonyloxy)methyl, (acyloxy)methyl and (oxodioxolenyl)methyl carbamates as bioreversible prodrug moieties for amines

Zhong Li, Panayota Bitha, Stanley A. Lang Jr., Yang-I Lin

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 178 KB

english, 1997

22

Contributors to this issue

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 51 KB

english, 1997

23

Graphical abstracts

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 297 KB

english, 1997

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