Volume 7; Issue 23

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Bioorganic & Medicinal Chemistry Letters
Volume 7; Issue 23

Bioorganic & Medicinal Chemistry Letters

Volume 7; Issue 23

1

Synthesis of conformationally restricted progestational 13-ethylsteroids

A.I.A. Broess, M.B. Groen, H. Hamersma

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 397 KB

english, 1997

2

Synthesis of 11,13-bridged progestational steroids

A.I.A. Broess, M.B. Groen, H. Hamersma

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 244 KB

english, 1997

3

Synthesis and in vitro cytotoxic activity of novel hexahydro-2H-pyrido[1,2-b]isoquinolines against human brain tumor cell lines

Axel Monsees, Sabine Laschat, Marc Hotfilder, Johannes Wolff, Klaus Bergander, Lothar Terfloth, Roland Fröhlich

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 280 KB

english, 1997

4

Naphtho-fused azepines as potent growth hormone secretagogues

Thomas Kruse Hansen, Henning Thøgersen, Birgit Sehested Hansen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 204 KB

english, 1997

5

Synthesis of 2′-O-[(4″-O-stearoyl)-α-l-fucopyranosyl]thymidine: A shimofuridin analogue

Jun Ning, Fanzuo Kong

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 209 KB

english, 1997

6

A novel series of 4-phenoxyquinolines: potent and highly selective inhibitors of PDGF receptor autophosphorylation

Kazuo Kubo, Toshiyuki Shimizu, Shin-ichi Ohyama, Hideko Murooka, Tsuyoshi Nishitoba, Shinichiro Kato, Yoshiko Kobayashi, Mikio Yagi, Toshiyuki Isoe, Kazuhide Nakamura, Tatsushi Osawa, Toshio Izawa

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 276 KB

english, 1997

7

3-Benzyloxy-2-phenylpiperidine NK1 antagonists: the influence of alpha methyl substitution

C.J. Swain, B.J. Williams, R. Baker, M.A. Cascieri, G. Chicchi, M. Forrest, R. Herbert, L. Keown, T. Ladduwahetty, S. Luell, D.E. MacIntyre, J. Metzger, S. Morton, A.P. Owens, S. Sadowski, A.P. Watt

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 176 KB

english, 1997

8

Pyrrolooctahydroisoquinolines as potent and selective ° opioid receptor ligands: SAR analysis and docking studies

Giulio Dondio, Silvano Ronzoni, Paola Petrillo, Renee L. DesJarlais, Luca F. Raveglia

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 326 KB

english, 1997

9

Novel phenyl nitrogen mustard and half-mustard derivatives of amidino-modified distamycin

Paolo Cozzi, Italo Beria, Giovanni Biasoli, Marina Caldarelli, Laura Capolongo, Cristina Geroni, Nicola Mongelli

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 311 KB

english, 1997

10

Novel phenyl nitrogen mustard and half-mustard derivatives of distamycin A

Paolo Cozzi, Italo Beria, Giovanni Biasoli, Marina Caldarelli, Laura Capolongo, Roberto D'Alessio, Cristina Geroni, Stefania Mazzini, Enzio Ragg, Carla Rossi, Nicola Mongelli

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 342 KB

english, 1997

11

New 7-aryl analogues of anthracyclines: Synthesis and cytotoxic activity of (±)-7-(3,4,5-trimethoxyphenyl)-7-deoxyidarubicinone

J.C. Acosta, E. Caballero, D.Ga Grávalos, M. Medarde, H. Sahagún, R.J. Stoodley, F. Tomé

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 242 KB

english, 1997

12

Reversible acylation of elastase by γ-lactam analogues of β-lactam inhibitors

Nicholas J Westwood, Timothy D.W Claridge, Philip N Edwards, Christopher J Schofield

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 334 KB

english, 1997

13

First synthesis and cytotoxic activity of novel docetaxel analogs modified at the C18-position

Kouichi Uoto, Ikuo Mitsui, Hirofumi Terasawa, Tsunehiko Soga

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 247 KB

english, 1997

14

Novel conformationally constrained analogues of diacylglycerol. Protein kinase C binding affinity of simplified compounds based on a 6-membered lactam moiety

Yasuyuki Endo, Masaaki Hirano, Paul E. Driedger, Silvia Stabel, Koichi Shudo

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 269 KB

english, 1997

15

One step synthesis of orthogonally protected diaminodicarboxylic acids by mixed kolbe electrolysis

Johann Hiebl, Hermann Kollmann, Franz Rovenszky, Karin Winkler

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 244 KB

english, 1997

16

Synthesis and characterization of a novel ranitidine dimer

Rogelio P. Frutos, Gregory P. Roth

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 208 KB

english, 1997

17

N-Hydroxyglycine derivatives as novel inhibitors of squalene synthase

Sompong Wattanasin, Brian R. Boettcher, Terry Scallen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 276 KB

english, 1997

18

Syntheses of and chemotactic responses elicited by fMet-Leu-Phe analogs containing difluoro- and trifluoromethionine

Michael E. Houston, Liana Harvath, John F. Honek

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 344 KB

english, 1997

19

Acyclic nucleoside triphosphate analogs as terminators in biocatalytic DNA replication

Carlos I. Martinez, M. Ali Ansari, Richard Gibbs, Kevin Burgess

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 209 KB

english, 1997

20

Synthesis and membrane permeability of PNA-peptide conjugates

Carla G. Simmons, Anne E. Pitts, Lynn D. Mayfield, Jerry W. Shay, David R. Corey

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 365 KB

english, 1997

21

Diastereoselective synthesis of trans-2-(1-triphenylmethyl-1H-imidazol-4-yl)cyclopropanecarboxylic acids: key intermediates for the preparation of potent and chiral histamine H3 receptor agents

M.Amin Khan, Stephen L. Yates, Clark E. Tedford, Kristin Kirschbaum, James G. Phillips

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 423 KB

english, 1997

22

Design and synthesis of 3,5-dialkylamino substituted 8H,10H-3(R),5(R),15b(S)-2,3,6,7-tetrahydro-1,5,3-dioxazepino[3,2-c]indolo[3,2-g]pteridine-7-ones

Ping Ge, Thomas I. Kalman

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 171 KB

english, 1997

23

A novel photoaffinity label for the dopamine transporter based on N-substituted 3α-[bis(4′-fluorophenyl)methoxy]tropane

Gregory E. Agoston, Roxanne Vaughan, John R. Lever, Sari Izenwasser, Phyllis D. Terry, Amy Hauck Newman

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 248 KB

english, 1997

24

N-linked glycoside/glucuronide conjugates of retinoids: acitretin

V. Balakrishnan, N.E. Gilbert, R.W. Brueggemeier, R.W. Curley Jr.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 269 KB

english, 1997

25

Fluorescent molecular probes III. 2′,7′-Bis-(3-carboxypropyl)-5-(and-6)-carboxyfluorescein (BCPCF): a new polar dual-excitation and dual-emission pH indicator with a pKa of 7.0

Jixiang Liu, Zhenjun Diwu, Dieter H. Klaubert

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 197 KB

english, 1997

26

Structure-activity relationships study at the 3′-N position of paclitaxel-part 1: Synthesis and biological evaluation of the 3′-(t)-butylaminocarbonyloxy bearing paclitaxel analogs

Shu-Hui Chen, May Xue, Stella Huang, Byron H Long, Craig A Fairchild, William C Rose, John F Kadow, Dolatrai Vyas

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 256 KB

english, 1997

27

Synthesis and structure-activity relationships of novel THF 1β-methylcarbapenems II

Yang-I Lin, Panayota Bitha, Subas M. Sakya, Stanley A. Lang Jr., Youjun Yang, William J. Weiss, Peter J. Petersen, Karen Bush, Raymond T. Testa

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 230 KB

english, 1997

28

Eicosanoid biosynthesis: differential inhibition of cytochrome P450 epoxygenase and ω-hydroxylase

J.R. Falck, Yuri Y. Belosludtsev, K.Kishta Reddy, Komandla Malla Reddy, M.Fiona Shortt, Kamlesh Chauhan, Jorge H. Capdevila, Shozou Wei

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 201 KB

english, 1997

29

The stereochemical requirements of the novel δ-opioid selective dipeptide antagonist TMT-Tic

Subo Liao, Jun Lin, Mark D. Shenderovich, Yinglin Han, Keiko Hasohata, Peg Davis, Wei Qiu, Frank Porreca, Henry I. Yamamura, Victor J. Hruby

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 243 KB

english, 1997

30

Additions and corrections

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

File:

PDF, 18 KB

1997

31

Contributors to this issue

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 83 KB

english, 1997

32

Graphical abstracts

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 402 KB

english, 1997

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