Volume 8; Issue 24

Main
Bioorganic & Medicinal Chemistry Letters
Volume 8; Issue 24

Bioorganic & Medicinal Chemistry Letters

Volume 8; Issue 24

1

Dual antagonists of platelet activating factor and histamine 3. synthesis, biological activity and conformational implications of substituted N-acyl-bis-arylcycloheptapiperazines

John J. Piwinski, Jesse K. Wong, Michael J. Green, James J. Kaminski, Frank Colizzo, Margaret M. Albanese, Ashit K. Ganguly, M.Motasim Billah, John C. Anthes, Robert E. West Jr.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 333 KB

english, 1998

2

Antiinflammatory 4,5-diarylimidazoles as selective cyclooxygenase inhibitors

Thomas E. Barta, Michael A. Stealey, Paul W. Collins, Richard M. Weier

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 238 KB

english, 1998

3

Anti-HIV coumarins from calophyllum seed oil

Claude Spino, Marco Dodier, Subramaniam Sotheeswaran

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 160 KB

english, 1998

4

Coprophilin: An anticoccidial agent produced by a dung inhabiting fungus

John G. Ondeyka, Robert A. Giacobbe, Gerald F. Bills, Cristina Cuadrillero, Dennis Schmatz, Michael A. Goetz, Deborah L. Zink, Sheo B. Singh

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 234 KB

english, 1998

5

Novel cytotoxic diterpenes from the stem of dysoxylum kuskusense

Toshihiro Fujioka, Miyako Yamamoto, Yoshiki Kashiwada, Hiroko Fujii, Kunihide Mihashi, Yasumasa Ikeshiro, Ih-Sheng Chen, Kuo-Hsiung Lee

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 235 KB

english, 1998

6

Aromatic analogs of arcaine inhibit MK-801 binding to the NMDA receptor

Terre A. Sharma, Andrew J. Carr, Rebecca S. Davis, Ian.J. Reynolds, Andrew D. Hamilton

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 382 KB

english, 1998

7

An improved route to 1,2-dideoxy-β-1-phenyl-d-ribofuranose

Uthai Wichai, Stephen A. Woski

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 228 KB

english, 1998

8

The use of neamine as a molecular template: Inactivation of bacterial antibiotic resistance enzyme aminoglycoside 3′-phosphotransferase type IIa

Juliatiek Roestamadji, Shahriar Mobashery

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 378 KB

english, 1998

9

The use of neamine as a molecular template: Identification of active site residues in the bacterial antibiotic resistance enzyme aminoglycoside 3′-phosphotransferase type IIa by mass spectroscopy

Yi Yang, Juliatiek Roestamadji, Shahriar Mobashery, Ron Orlando

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 262 KB

english, 1998

10

Synthesis and structure-activity relationships of adenosine analogs as inhibitors of trypanosomal glyceraldehyde-3-phosphate dehydrogenase. Modifications at positions 5′ and 8

Alex M. Aronov, Michael H. Gelb

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 294 KB

english, 1998

11

Potent and selective thrombin inhibitors featuring hydrophobic, basic P3P4-aminoalkyllactam moieties

J.Edward Semple, David C. Rowley, Timothy D. Owens, Nathaniel K. Minami, Theresa H. Uong, Terence K. Brunck

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 364 KB

english, 1998

12

Synthesis and antiplatelet effects of an isoxazole series of glycoprotein IIb/IIIa antagonists

Chu-Biao Xue, John Roderick, Shaker Mousa, Richard E. Olson, William F. DeGrado

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 271 KB

english, 1998

13

Organometallic flavonoid derivatives as spectroscopic probes

Christopher E. Anson, Colin S. Creaser, J.Allan Downie, Orsolya Egyed, Andrej V. Malkov, Ljubica Mojovic, G.Richard Stephenson, Andrew T. Turner, Karen E. Wilson

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 351 KB

english, 1998

14

Butyrophenone analogues in the carbazole series: Synthesis and determination of affinities at D2 and 5-HT2A receptors

Christian F. Masaguer, Emilio Formoso, Enrique Raviña, Helena Tristán, M.Isabel Loza, Emilia Rivas, JoséAngel Fontenla

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 381 KB

english, 1998

15

The Discovery of orally available thrombin inhibitors : Studies towards the optimisation of CGH1668

John Ambler, Emma Baker, Lyndon Brown, Paul Butler, Dave Farr, Karen Dunnet, Darren Le Grand, Diana Janus, Darryl Jones, Keith Menear, Mark Mercer, Garrick Smith, Mark Talbot, Morris Tweed

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 275 KB

english, 1998

16

Design and synthesis of new secretory phospholipase A2 inhibitor of a phospholipid analog

Seiji Iwama, Masaki Segawa, Shinobu Fujii, Kiyoshi Ikeda, Shigeo Katsumura

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 238 KB

english, 1998

17

Methionine analogues as inhibitors of methionyl-tRNA synthetase

Jeewoo Lee, Mee Kyoung Kang, Moon Woo Chun, Yeong Joon Jo, Jin Hwan Kwak, Sunghoon Kim

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 306 KB

english, 1998

18

Inhibition stereochemistry of hydroxamate inhibitors for thermolysin

Yonghao Jin, Dong H. Kim

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 203 KB

english, 1998

19

Cytotoxic cycloartane-type triterpenes from Combretum quadrangulare

Arjun H. Banskota, Yasuhiro Tezuka, Le Kim Phung, Kim Qui Tran, Ikuo Saiki, Yoshihisa Miwa, Tooru Taga, Shigetoshi Kadota

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 407 KB

english, 1998

20

Synthesis and phototoxic property of tetra- and octa-glycoconjugated tetraphenylchlorins

Yuji Mikata, Yoko Onchi, Minako Shibata, Toyoji Kakuchi, Hiroshi Ono, Shun-ichiro Ogura, Ichiro Okura, Shigenobu Yano

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 305 KB

english, 1998

21

Phenylpiperazine derivatives with strong affinity for 5HT1A, D2A and D3 receptors

Carmen Terán, Lourdes Santana, Eugenio Uriarte, Yagamare Fall, Lena Unelius, Bo-Ragnar Tolf

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 228 KB

english, 1998

22

The solid phase synthesis of a series of tri-substituted hydantoin ligands for the somatostatin SST5 receptor

Jan J. Sciciński, Michael D. Barker, Peter John Murray, Emma M. Jarvie

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 285 KB

english, 1998

23

Design and synthesis of a novel class of nucleotide analogs with anti-HCMV activity

Paul Nguyen-Ba, Nola Lee, Helen Mitchell, Laval Chan, Miguel Quimpère

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 229 KB

english, 1998

24

Identification of novel nucleotide phosphonate analogs with potent anti-HCMV activity

Paul Nguyen-Ba, Nathalie Turcotte, Leonard Yuen, Jean Bédard, Miguel Quimpère, Laval Chan

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 256 KB

english, 1998

25

Novel acylguanidine containing thrombin inhibitors with reduced basicity at the P1 moiety

Anton E.P. Adang, Hans Lucas, Adrianus P.A. de Man, Richard A. Engh, Peter D.J. Grootenhuis

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 347 KB

english, 1998

26

4,4,14α-trimethyl 9β,19-cyclo-5α-26-homocholesta-24,26-dien-3β-ol: a potent mechanism-based inactivator of Δ24(25)- to Δ25(27)-sterol methyl transferase

W. David Nes, Ling He, Anil T. Mangla

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 237 KB

english, 1998

27

Facile synthesis of high affinity styrylpyridine systems as inherently fluorescent ligands for the estrogen receptor

Marvin J. Meyers, Kathryn E. Carlson, John A. Katzenellenbogen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 349 KB

english, 1998

28

Potent piperazine hydroxyethylamine HIV protease inhibitors containing novel P3 ligands

Xiaoqi Chen, Dale J. Kempf, Hing L. Sham, Brian E. Green, Akhteruzaman Molla, Marina Korneyeva, Sudthida Vasavanonda, Norman E. Wideburg, Ayda Saldivar, Kennan C. Marsh, Edith McDonald, Daniel W. Norb

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 327 KB

english, 1998

29

Development of 2,2-dimethylchromanol cysteinyl LT1 receptor antagonists

R.J. Chambers, G.W. Antognoli, J.B. Cheng, A.V. Kuperman, T.C. Liston, A. Marfat, B.S. Owens, J.S. Pillar, J.T. Shirley, J.W. Watson

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 316 KB

english, 1998

30

Synthesis of photoaffinity label analogues of α-tocopherol

Huangshu Lei, Virginia Marks, Tony Pasquale, Jeffrey K. Atkinson

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 323 KB

english, 1998

31

TracermerTM signal generators: An arborescent approach to the incorporation of multiple chemiluminescent labels

Maciej Adamczyk, Jeffrey Fishpaugh, Phillip G. Mattingly, Kevin Shreder

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 177 KB

english, 1998

32

Unsymmetric nonpeptidic HIV protease inhibitors containing anthranilamide as a P2′ ligand

Ramnarayan S. Randad, Lucyna Lubkowska, Michael A. Eissenstat, Sergei V. Gulnik, Betty Yu, T. Narayana Bhat, David J. Clanton, Tyra House, Sherman F. Stinson, John W. Erickson

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 350 KB

english, 1998

33

O-(Fluoresceinylmethyl)hydroxylamine (OFMHA): A fluorescent reagent for detection of damaged nucleic acids

Maciej Adamczyk, Phillip G Mattingly, Jeffrey A Moore

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 188 KB

english, 1998

34

Tricyclic ureas: A new class of HIV-1 protease inhibitors

Wei Han, Jeffrey C. Pelletier, C.Nicholas Hodge

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 276 KB

english, 1998

35

(2Z,4E)-5-(5,6-dichloro-2-indolyl)-2-methoxy-N-(1,2,2,6,6-pentamethylpiperidin-4-yl)-2,4-pentadienamide, a novel, potent and selective inhibitor of the osteoclast V-ATPase

Guy Nadler, Marcel Morvan, Isabelle Delimoge, Pietro Belfiore, Andrea Zocchetti, Ian James, Denise Zembryki, Elizabeth Lee-Rycakzewski, Carlo Parini, Emanuela Consolandi, Stefania Gagliardi, Carlo Far

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 313 KB

english, 1998

36

Synthesis of 6(α,β)-aminocholestanols as ergosterol biosynthesis inhibitors

Pierre Beuchet, Laïla El kihel, Michel Dherbomez, Georges Charles, Yves Letourneux

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 221 KB

english, 1998

37

Synthesis and biological activity of [Tic5] didemnin B

Amy J. Pfizenmayer, Matthew D. Vera, Xiaobin Ding, Dong Xiao, Wei-Chuan Chen, Madeleine M. Joullié, Deepika Tandon, Peter L. Toogood

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 236 KB

english, 1998

38

Tobramycin-edta conjugate: A noninnocent affinity-cleaving reagent

Hai Wang, Yitzhak Tor

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 381 KB

english, 1998

39

Differential activity of rosiglitazone enantiomers at PPARγ

Derek J. Parks, Nicholas C.O. Tomkinson, Manon S. Villeneuve, Steven G. Blanchard, Timothy M. Willson

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 112 KB

english, 1998

40

Conjugation of oligonucleotides via an electrophilic tether: N-chloroacetamidohexyl phosphoramidite reagent

Andrei Guzaev, Muthiah Manoharan

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 318 KB

english, 1998

41

Benzothiopyran-4-one based reversible inhibitors of the human cytomegalovirus (HCMV) protease

Dashyant Dhanak, Richard M. Keenan, George Burton, Arun Kaura, Michael G. Darcy, Dinubhai H. Shah, Lance H. Ridgers, Ann Breen, Paddy Lavery, David G. Tew, Andrew West

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 340 KB

english, 1998

42

Alkoxide-catalyzed ring-opening of a novel homosaccharin derivative: synthesis of potent, selective P3-lactam thrombin inhibitors containing P4-o-alkoxycarbonylbenzylsulfonamide residues

Timothy D. Owens, J. Edward Semple

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 378 KB

english, 1998

43

N6-(5,6-epoxynorbornyl)adenosine analogs as A1 adenosine agonists

Denis M.J. Wright, Stephen P. Baker, Scott G. Stewart, Peter J. Scammells

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 144 KB

english, 1998

44

Design, synthesis, and conformational analysis of a novel series of HIV protease inhibitors

Christopher T. Baker, Francesco G. Salituro, John J. Court, David D. Deininger, Eunice E. Kim, Biquin Li, Perry M. Novak, Bhisetti G. Rao, S. Pazhanisamy, Wayne C. Schairer, Roger D. Tung

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 305 KB

english, 1998

45

Design and synthesis of novel conformationally restricted HIV protease inhibitors

Francesco G. Salituro, Christopher T. Baker, John J. Court, David D. Deininger, Eunice E. Kim, Biquin Li, Perry M. Novak, Bhisetti G. Rao, S. Pazhanisamy, Margaret D. Porter, Wayne C. Schairer, Roger

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 293 KB

english, 1998

46

Novel cytokine release inhibitors. Part III: Truncated analogs of tripterine

Wei He, Fu-Chih Huang, Ashvin Gavai, Wan K. Chan, George Amato, Kin-Tak Yu, Asher Zilberstein

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 271 KB

english, 1998

47

Synthesis and guanase inhibition studies of a novel ring-expanded purine analogue containing a 5:7-fused, planar, aromatic heterocyclic ring system

Vasanthakumar Rajappan, Ramachandra S. Hosmane

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 260 KB

english, 1998

48

Synthesis and transporter binding properties of (R)-2β,3β- and (R)-2α,3α-diaryltropanes

Songchun Jiang, An-Chih Chang, Philip Abraham, Michael J. Kuhar, F.Ivy Carroll

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 231 KB

english, 1998

49

Synthesis of gem-difluoro-avermectin derivatives: Potent anthelmintic and anticonvulsant agents

Peter T. Meinke, Wesley L. Shoop, Bruce F. Michael, Timothy A. Blizzard, Gerard R. Dawson, Michael H. Fisher, Helmut Mrozik

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 259 KB

english, 1998

50

Contributors to this issue

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 124 KB

english, 1998

51

Graphical abstracts

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 750 KB

english, 1998

To build up a library is to create a life. It’s never just a random collection of books.

— Carlos María Domínguez

Official channel

Z-Library Desktop Launcher

Tor version

Z-Library

Z-Library Since 2009 support@z-lib.do

EnglishРусскийEspañolItalianoελληνικάاللغة العربيةBahasa IndonesiaBahasa Malaysiaहिन्दीDeutschFrançaisPortuguêsУкраїнськаPolski中文繁體中文日本語Tiếng ViệtAzərbaycan DiliՀայոց լեզուภาษาไทยTürk Diliქართველიবাংলাپښتوతెలుగుاردو한국어SrpskiБългарски